BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0013.0183.p (275 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr7896 [GER] COG0697 Permeases of the drug/metabolite transport... 228 9e-60 STM3796A [GER] COG0697 Permeases of the drug/metabolite transpor... 167 2e-41 BMEI1244 [GER] COG0697 Permeases of the drug/metabolite transpor... 164 1e-40 SMc01807 [GER] COG0697 Permeases of the drug/metabolite transpor... 163 3e-40 mll3062 [GER] COG0697 Permeases of the drug/metabolite transport... 161 1e-39 >mlr7896 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 278 Score = 228 bits (582), Expect = 9e-60, Method: Compositional matrix adjust. Identities = 132/271 (48%), Positives = 180/271 (66%) Query: 5 IVALILFAALLHASWNALLRGGADRLWSMTVMCLAVALASLAIALFLAPPAQASWMYAVL 64 ++ L LFAA+LHASWNA LR GADRLW++TVM + ++ +A+F PA ++W Y L Sbjct: 5 VIGLALFAAILHASWNAFLRTGADRLWTVTVMSFSDTALAIPLAIFNGFPATSAWPYVGL 64 Query: 65 SAVLHVGYNLFLVRSYRAGDLGQTYPISRGSSPLLITIAASAFAGERVAMSALLGIALVA 124 SA L VGY++FLV +YR G+LGQ YPI RGS PLL+T+ AG+++ + +G+ LV Sbjct: 65 SACLQVGYSVFLVAAYRYGELGQVYPIVRGSVPLLVTLGGFLLAGQQLTVPETVGVVLVG 124 Query: 125 GGIISLAFNGRKLAVPSLPYALGTGCFIAAYSVVDGIGVRLSGAPMAYTVWMCALWGVLM 184 GGI+ L+ + A S+ YAL TG IA Y+ VD IGVR +G AYT W+ +G L+ Sbjct: 125 GGIMGLSLGRGRAATTSILYALATGAIIAVYATVDAIGVRAAGNVGAYTAWVLLAYGALL 184 Query: 185 PAVYIGLRGANHLFTMRPGFSTAFMGGLVSLLAYGIVIYAMSGAPMGAVSALRETSVLFA 244 PA ++ RG + P A GGL +LLAYG+V+ A + P G ++A+RETSV+FA Sbjct: 185 PATFVACRGRLPVDPRAPETWKALGGGLFALLAYGVVVAAFALGPAGPITAIRETSVVFA 244 Query: 245 ALIGYFFLGETLTVRKMLACAVIAAGTIIIG 275 A IG FLGETLT R++ ACAV+A G I +G Sbjct: 245 AFIGRLFLGETLTPRRVGACAVVALGAICLG 275 >STM3796A [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sty Salmonella typhimurium LT2 Length = 286 Score = 167 bits (423), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 100/276 (36%), Positives = 164/276 (59%), Gaps = 4/276 (1%) Query: 1 MPFHIVALILFAALLHASWNALLRGGADRLWSMTVMCLAVALASLAIALFLAPPAQASWM 60 M + ++LFAALLHASWNA+++ G D+L++ + + A+ +L + F PA AS Sbjct: 10 MTLSVFCILLFAALLHASWNAIVKAGNDKLYAAIGVSGSAAVMALILLPFSPQPAHASIP 69 Query: 61 YAVLSAVLHVGYNLFLVRSYRAGDLGQTYPISRGSSPLLITIAASAFAGERVAMSALLGI 120 + S L V Y + + ++Y+ D+ QTYP+ RG++PLL+ + + F G+ ++ A +GI Sbjct: 70 FLAASTALQVVYTVLVAKTYQVSDMSQTYPLMRGTAPLLVALISVLFLGDSLSSLAWVGI 129 Query: 121 ALVAGGIISLAFNGRKLAVPSLPYALGTGCFIAAYSVVDGIGVRLSGAPMAYTVWMCALW 180 A++ I+ +A NGR + + AL CFIA Y++VDG GVRLS + YT+W L Sbjct: 130 AVICMAILGMACNGRASSQRGVVLALTNACFIAGYTLVDGTGVRLSETALGYTLWSFFLN 189 Query: 181 G--VLMPAVYIGLRGANHLFTMRPGFSTAFMGGLVSLLAYGIVIYAMSGAPMGAVSALRE 238 G +L A+ R A+ + + GG+ ++ +YG+ ++AM+ AP+ V+ALRE Sbjct: 190 GACLLTWAMIARRREASRYLAQQ--WKKGIFGGIGTMGSYGLALWAMTQAPLAVVAALRE 247 Query: 239 TSVLFAALIGYFFLGETLTVRKMLACAVIAAGTIII 274 TS+LF ALI + L E + +++A IA G I++ Sbjct: 248 TSILFGALIAWLLLKEKVAGLRLVAAGGIALGAILL 283 >BMEI1244 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bme Brucella melitensis Length = 281 Score = 164 bits (416), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 91/272 (33%), Positives = 160/272 (58%), Gaps = 4/272 (1%) Query: 5 IVALILFAALLHASWNALLRGGADRLWSMTVMCLAVALASLAIALFLAPPAQASWMYAVL 64 ++ ++LF A LH SWNA+++G D+ + + A L +L + FL P ASW+Y +L Sbjct: 5 VLLIVLFGAFLHTSWNAIVKGSGDKFFGAASVTGAAGLIALFLVPFLPLPTAASWIYMLL 64 Query: 65 SAVLHVGYNLFLVRSYRAGDLGQTYPISRGSSPLLITIAASAFAGERVAMSALLGIALVA 124 S + Y + +Y++GD+ + YPI RG+ PLL+ + + GE + + LGI L+ Sbjct: 65 STITQTFYMSLVAAAYKSGDMSEAYPIMRGTPPLLVALVSGPLVGEIMGWQSWLGIVLIC 124 Query: 125 GGIISLAFNGRKL----AVPSLPYALGTGCFIAAYSVVDGIGVRLSGAPMAYTVWMCALW 180 G++++A + R+ + ++ AL FIA+Y+++DG+GVR+SG P++YT+W+ L Sbjct: 125 SGVLAMALDARRRNRGASSRTVLLALANAGFIASYTLIDGLGVRVSGEPLSYTLWLFLLN 184 Query: 181 GVLMPAVYIGLRGANHLFTMRPGFSTAFMGGLVSLLAYGIVIYAMSGAPMGAVSALRETS 240 V + + + + +R + A +GG+ +L +YG+ ++AM+ AP+ V+ALRET+ Sbjct: 185 AVPLAGWALYREPSRFINYIRNRWRPALIGGVGTLGSYGLALWAMTMAPIAVVAALRETA 244 Query: 241 VLFAALIGYFFLGETLTVRKMLACAVIAAGTI 272 +LF LI L E + + + +A I AG I Sbjct: 245 ILFGMLISALILKEKVGLPRFVAAGFIVAGAI 276 >SMc01807 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 278 Score = 163 bits (413), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 98/271 (36%), Positives = 159/271 (58%), Gaps = 7/271 (2%) Query: 1 MPFHIVALILFAALLHASWNALLRGGADRLWSMTVMCLAVALASLAIALFLAPPAQASWM 60 MP ++AL+L ALLHA+WNAL++ G ++ ++ L A+ +L FL P + Sbjct: 1 MPPDVIALVLLGALLHATWNALVKAGTEKSLDAAMVSLGGAVVALPFLPFLPMPGSEAVP 60 Query: 61 YAVLSAVLHVGYNLFLVRSYRAGDLGQTYPISRGSSPLLITIAASAFAGERVAMSALLGI 120 Y ++SA+ Y + +YRAGD+G YP+ RG +PL++ +S GE++ A+ GI Sbjct: 61 YILVSALFQFAYFQLVAAAYRAGDIGLVYPLMRGVAPLIVAATSSLVIGEKLTGGAMAGI 120 Query: 121 ALVAGGIISLAFNGRKLAVPSLPYALGTGCFIAAYSVVDGIGVRLSGAPMAYTVWMCALW 180 ++ G+++LAF RK ++ AL C IA+Y+ VDGIG R+SG ++YT+WM L Sbjct: 121 MTISAGVLTLAFESRKGGRHAIVLALLNACVIASYTYVDGIGARISGNAISYTLWMALLP 180 Query: 181 GVLMPAVYIGLRG----ANHLFTMRPGFSTAFMGGLVSLLAYGIVIYAMSGAPMGAVSAL 236 VL+ RG A H+ + +GG S+ +YG+ ++AM+ AP+ V+AL Sbjct: 181 PVLLFGWAFARRGVKPVARHVSRH---WWRGLIGGAGSIGSYGLALWAMTKAPVATVAAL 237 Query: 237 RETSVLFAALIGYFFLGETLTVRKMLACAVI 267 RET++LFA +I FL E ++ +++A +I Sbjct: 238 RETAILFAVVISVVFLKERVSAWRIIAAFII 268 >mll3062 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 281 Score = 161 bits (408), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 99/261 (37%), Positives = 153/261 (58%), Gaps = 10/261 (3%) Query: 19 WNALLRGGADRLWSMTVMCLAVALASLAIALFLAPPAQASWMYAVLSAVLHVGYNLFLVR 78 WNAL++ DR S+T+M L + A+L + F+ P W + + S V H+GY FL+ Sbjct: 19 WNALVKVHLDRFLSITLMTLGMGFAALFVLPFVEFPKAEVWPFILASVVFHMGYRTFLIG 78 Query: 79 SYRAGDLGQTYPISRGSSPLLITIAASAFAGERVAMSALLGIALVAGGIISLAFNG---- 134 +YRAGD QTYP++RG++PLL + E A A+LGI L++ G + ++F G Sbjct: 79 AYRAGDFAQTYPLARGTAPLLAALGGIVVVQEVPAPFAILGILLLSAGTLVMSFRGGAHL 138 Query: 135 RKLAVPSLPYALGTGCFIAAYSVVDGIGVRLSGAPMAYTVWM--C-ALWGVLMPAVYIGL 191 +L + ++ +ALGT FIA+Y++ DG G RL+ +Y W+ C A W +++ V+ Sbjct: 139 ERLNLRAVGFALGTSIFIASYTLSDGSGARLAATAQSYAAWLFVCDATWALVLCVVF--- 195 Query: 192 RGANHLFTMRPGFSTAFMGGLVSLLAYGIVIYAMSGAPMGAVSALRETSVLFAALIGYFF 251 RG L + + G++S AY IV++AM+ AP+ +V++LRETS+LFA LI + Sbjct: 196 RGPQSLPVLARDWKAGLFTGVLSGAAYWIVMWAMTKAPIASVASLRETSILFAMLISVYA 255 Query: 252 LGETLTVRKMLACAVIAAGTI 272 LGE +T + A I AG I Sbjct: 256 LGEKMTGWRGAAALSIVAGVI 276