BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0013.0163.p (281 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc00270 [G] COG3959 Transketolase, N-terminal subunit Sme Sinor... 410 e-114 mll5765 Non COG 380 e-105 TM0954 [G] COG3959 Transketolase, N-terminal subunit Tma Thermot... 202 9e-52 FN0294 [G] COG3959 Transketolase, N-terminal subunit Fnu Fusobac... 190 3e-48 SP2128 [G] COG3959 Transketolase, N-terminal subunit Spn Strepto... 166 4e-41 >SMc00270 [G] COG3959 Transketolase, N-terminal subunit Sme Sinorhizobium meliloti Length = 284 Score = 410 bits (1054), Expect = e-114, Method: Compositional matrix adjust. Identities = 200/266 (75%), Positives = 224/266 (84%) Query: 7 SLRASAYRIRRFAVRMGEVQGQGYIGQALGWADVLAVAYKRAMQIRPMEPEWEGRDRFLL 66 SL A+ IRR AVRMGEVQGQGY+GQALG ADVLAV+Y A+ R +PEWEGRDRFLL Sbjct: 14 SLARRAWEIRRKAVRMGEVQGQGYVGQALGIADVLAVSYFHALTYRRQDPEWEGRDRFLL 73 Query: 67 SHGHYAIAAYAALIEAGILPEEELETYGSDDSRLPMSGMAAYTPGMEISGGSLGQGLAIG 126 S GHYAIA YAALIEAGILPE+ELETYG+DDSRLPMSGMAAYTPGMEI+GGSLGQGL IG Sbjct: 74 SIGHYAIALYAALIEAGILPEQELETYGTDDSRLPMSGMAAYTPGMEITGGSLGQGLGIG 133 Query: 127 VGMALALRHKGSASFVYNSMSDGELDEGATWEAAMGAAHHNLGNLICLVDINNQQADGPS 186 VGMAL L+ K + +FVYN MSDGEL EG+TWEAAM AAHH LGNLICLVD N+QQADG S Sbjct: 134 VGMALGLKAKKNPAFVYNLMSDGELGEGSTWEAAMSAAHHKLGNLICLVDFNDQQADGKS 193 Query: 187 GKIMGFEPLADKWASFGWHVQRVDGNDLPAVIAAFDQARQLPESKPRVILFDTLMGKGVP 246 +++ EPL KWA+FGWHVQRVDGND+PA++AAFD AR L E+ PRVI+ DTLM KGVP Sbjct: 194 TEMLCSEPLGAKWAAFGWHVQRVDGNDIPALVAAFDAARALEEAMPRVIICDTLMCKGVP 253 Query: 247 FLEQREKNHFIRVDPPEWQQALNILD 272 FLEQRE HF+RVD EWQ+AL LD Sbjct: 254 FLEQREVTHFVRVDADEWQKALAALD 279 >mll5765 Non COG Length = 279 Score = 380 bits (977), Expect = e-105, Method: Compositional matrix adjust. Identities = 186/267 (69%), Positives = 213/267 (79%) Query: 7 SLRASAYRIRRFAVRMGEVQGQGYIGQALGWADVLAVAYKRAMQIRPMEPEWEGRDRFLL 66 SL AYRIRR AVRMGEVQGQGY+GQALG ADVLAVAY A++ RP + WEGRDRFLL Sbjct: 9 SLAERAYRIRRHAVRMGEVQGQGYVGQALGVADVLAVAYFHALRYRPDDTLWEGRDRFLL 68 Query: 67 SHGHYAIAAYAALIEAGILPEEELETYGSDDSRLPMSGMAAYTPGMEISGGSLGQGLAIG 126 S GHYAIA YAALIEAG+LPEEELETYG+DDSR+PMSGMAAYTPGMEI+GGSLG GL I Sbjct: 69 SIGHYAIALYAALIEAGVLPEEELETYGTDDSRMPMSGMAAYTPGMEITGGSLGHGLGIA 128 Query: 127 VGMALALRHKGSASFVYNSMSDGELDEGATWEAAMGAAHHNLGNLICLVDINNQQADGPS 186 VGM L L+ K S FVYN +SDGEL EG+TWEAAM AAHH L NLI +VD NN QADGPS Sbjct: 129 VGMCLGLKRKQSDCFVYNLLSDGELGEGSTWEAAMSAAHHKLDNLIAIVDFNNLQADGPS 188 Query: 187 GKIMGFEPLADKWASFGWHVQRVDGNDLPAVIAAFDQARQLPESKPRVILFDTLMGKGVP 246 ++ EP+ DK+ +FGWH QRVDGND+ A+ AAFD AR L + +PR+I+ DT M KGVP Sbjct: 189 TAMLSSEPVTDKFEAFGWHAQRVDGNDIEALRAAFDNARGLKDPRPRIIVCDTRMAKGVP 248 Query: 247 FLEQREKNHFIRVDPPEWQQALNILDQ 273 FLE R+ HFIRV+P EW AL L++ Sbjct: 249 FLEARDITHFIRVEPYEWALALEALEK 275 >TM0954 [G] COG3959 Transketolase, N-terminal subunit Tma Thermotoga maritima Length = 286 Score = 202 bits (513), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 107/269 (39%), Positives = 159/269 (59%), Gaps = 2/269 (0%) Query: 8 LRASAYRIRRFAVRMGEVQGQGYIGQALGWADVLAVAYKRAMQIRPMEPEWEGRDRFLLS 67 L+ A IR+ + M G+ G +L ++L + + ++++P +P WE RDRF+LS Sbjct: 12 LKRKAIEIRKMILDMIYKAKSGHTGGSLSSVEILVTLFYKILRVKPEDPNWEDRDRFILS 71 Query: 68 HGHYAIAAYAALIEAGILPEEELETYGSDDSRLPMSGMAAYTPGMEISGGSLGQGLAIGV 127 GH A YA L + G P+EELETY SRL PG+E++ G+LG GLAIGV Sbjct: 72 KGHSVEAYYAVLADKGFFPKEELETYCKYGSRLT-GHPTRKVPGVEVNTGALGHGLAIGV 130 Query: 128 GMALALRHKGSASFVYNSMSDGELDEGATWEAAMGAAHHNLGNLICLVDINNQQADGPSG 187 GMALA + G VY M DGELDEG+ WEAA A+H++L NLI +VD N Q G + Sbjct: 131 GMALAGKMDGKDYKVYVLMGDGELDEGSVWEAAQVASHYSLDNLIGIVDRNRLQISGHTE 190 Query: 188 KIMGFEPLADKWASFGWHVQRVDGNDLPAVIAAFDQARQLPESKPRVILFDTLMGKGVPF 247 +++ EPL+ +W +FGW+V VDG+D ++ F + KP +I+ +T+ GKG+ F Sbjct: 191 EVLKLEPLSKRWEAFGWNVLEVDGHDFESLYKTFVSIPR-ETGKPHLIIANTIKGKGISF 249 Query: 248 LEQREKNHFIRVDPPEWQQALNILDQSYK 276 +E R + H E+++A+ L++ K Sbjct: 250 IEGRVEWHHKVPSDEEYRKAIEELEEQLK 278 >FN0294 [G] COG3959 Transketolase, N-terminal subunit Fnu Fusobacterium nucleatum Length = 270 Score = 190 bits (483), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 107/266 (40%), Positives = 148/266 (55%), Gaps = 1/266 (0%) Query: 3 ENLESLRASAYRIRRFAVRMGEVQGQGYIGQALGWADVLAVAYKRAMQIRPMEPEWEGRD 62 +++ L+ A IR+ V M G+ G +L D+L Y M + P P+ EGRD Sbjct: 2 KDISFLKEKAKEIRKSIVSMIAEAKSGHPGGSLSATDILTALYFSEMNVDPTNPKMEGRD 61 Query: 63 RFLLSHGHYAIAAYAALIEAGILPEEELETYGSDDSRLPMSGMAAYTPGMEISGGSLGQG 122 RF+LS GH A A YA L E G ++EL T SRL G+EIS GSLGQG Sbjct: 62 RFVLSKGHAAPAIYATLAEKGYFSKDELMTLRKFGSRLQGHPDMKKLSGIEISTGSLGQG 121 Query: 123 LAIGVGMALALRHKGSASFVYNSMSDGELDEGATWEAAMGAAHHNLGNLICLVDINNQQA 182 L++ GMAL + Y + DGE+ EG WEAAM AAH+ L NL +D NN Q Sbjct: 122 LSVANGMALNAKIFDENYRTYVVLGDGEIQEGQIWEAAMTAAHYKLDNLCAFLDSNNLQI 181 Query: 183 DGPSGKIMGFEPLADKWASFGWHVQRVDGNDLPAVIAAFDQARQLPESKPRVILFDTLMG 242 DG +I G EPL KW +FGW+V ++DG+D +++A ++AR+ + KP +I+ T+ G Sbjct: 182 DGNVTEIKGVEPLDKKWEAFGWNVIKIDGHDFEQILSALEKAREC-KGKPTMIIAKTIKG 240 Query: 243 KGVPFLEQREKNHFIRVDPPEWQQAL 268 KGV F+E H + E ++AL Sbjct: 241 KGVSFMENVCGFHGVAPTVEELERAL 266 >SP2128 [G] COG3959 Transketolase, N-terminal subunit Spn Streptococcus pneumoniae TIGR4 Length = 285 Score = 166 bits (421), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 100/281 (35%), Positives = 152/281 (54%), Gaps = 7/281 (2%) Query: 1 MSENLES-LRASAYRIRRFAVRMGEVQGQGYIGQALGWADVLAVAYKRAMQIRPMEPE-W 58 +S+N E LR A IR +R G G+ G +L +VLAV Y M PM PE + Sbjct: 3 LSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVLAVLYGEIM---PMTPEIF 59 Query: 59 EGRDR--FLLSHGHYAIAAYAALIEAGILPEEELETYGSDDSRLPMSGMAAYTPGMEISG 116 RDR F+LS GH A Y+ L G +E L + ++ ++LP TPG++++ Sbjct: 60 AARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTKLPSHPDRNLTPGIDMTT 119 Query: 117 GSLGQGLAIGVGMALALRHKGSASFVYNSMSDGELDEGATWEAAMGAAHHNLGNLICLVD 176 GSLGQG+++ G+A R + S + Y + DGEL+EG WEA A+H L NLI VD Sbjct: 120 GSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCWEAIQFASHQQLSNLIVFVD 179 Query: 177 INNQQADGPSGKIMGFEPLADKWASFGWHVQRVDGNDLPAVIAAFDQARQLPESKPRVIL 236 N +Q DG + I +K+++FG+ RV G+D+ + Q +Q S P+ I+ Sbjct: 180 DNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIREIYEGIVQLKQSNNSSPKCIV 239 Query: 237 FDTLMGKGVPFLEQREKNHFIRVDPPEWQQALNILDQSYKE 277 DT+ G+GV LE+ + NH +R E Q +++++ +E Sbjct: 240 LDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVERLSQE 280