BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0013.0146.p (411 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1177 [GEPR] COG0477 Permeases of the major facilitator superf... 427 e-119 PA4622 [GEPR] COG0477 Permeases of the major facilitator superfa... 427 e-119 CAP0049 [GEPR] COG0477 Permeases of the major facilitator superf... 419 e-117 mlr4214 [GEPR] COG0477 Permeases of the major facilitator superf... 342 9e-94 SMc03237 [GEPR] COG0477 Permeases of the major facilitator super... 338 1e-92 >RSp1177 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 424 Score = 427 bits (1099), Expect = e-119, Method: Compositional matrix adjust. Identities = 243/411 (59%), Positives = 309/411 (75%), Gaps = 5/411 (1%) Query: 1 MTSAIAPEQLLHHR-----SFRLFWLASVTSTIALQMQIVAVGWQVYQLTHSPFDLGIVG 55 ++S AP Q L H +FRLFWLA +++T A QM VAVGWQ+Y LT S + LG+VG Sbjct: 7 LSSPPAPAQTLSHAPFAYPAFRLFWLARLSTTFAYQMFGVAVGWQIYDLTRSAYVLGLVG 66 Query: 56 LVQFIPSLFLVFVVGHVADRHDRRQVARFSILVEAIAAGLLAAGSLGGWLTKEAIFAIVF 115 L QF+PS+ LV GH+ADR+DRR+V R +EA+ A +LAA +L G + + IF V Sbjct: 67 LAQFLPSVVLVLASGHIADRYDRRRVVRICQAIEALVAAMLAAATLTGHASIQPIFVFVV 126 Query: 116 VIGAGRAFSKPTMSAMLPTLMQPSLLPRAVAGSASATQVAIIIGPAIGGFLYVAGPSTVY 175 VIGA RAF PT+ A+LP+L+ P+ LPRAVA S+SA Q II+GPA+GGFLYVAG VY Sbjct: 127 VIGAMRAFETPTLQALLPSLVPPAALPRAVALSSSAGQTGIILGPAVGGFLYVAGAPVVY 186 Query: 176 ITSCVLFVLCSVLVSMIKVETPPARRENATLKSVFAGIAYIRSKPAIFGAISLDLFAVLL 235 T+ LFVL VLV+ ++ +L+S+FAGIA+I+ +P + GAISLDLFAVLL Sbjct: 187 ATAAGLFVLAHVLVACVRTGRAAPVSRPVSLESLFAGIAFIKGRPVVLGAISLDLFAVLL 246 Query: 236 GGATALLPVYAHDILHTNSVGLGLLRSAPAVGALSVAIFLARNPLKGRIGRTMFIAVGIF 295 GGATALLP+YA DIL T + GLGLLRSAPA+GAL++AIFLA PL+ +GR MF AV +F Sbjct: 247 GGATALLPIYARDILGTGAWGLGLLRSAPAIGALAMAIFLAHRPLERHVGRVMFAAVALF 306 Query: 296 GLATIAFGLSQTFVVSLLALVVLGASDMISVVVRSTFVQLETPDDMRGRVSAVNSVFIGT 355 GLAT+ FG+S+ +S+LALVVLGA DM+SVV+R++ VQL+TPD MRGRVSAVNSVF+G Sbjct: 307 GLATMVFGVSRWLPLSMLALVVLGAGDMVSVVIRTSLVQLDTPDAMRGRVSAVNSVFVGA 366 Query: 356 SNQLGEFESGLTAAWFGAVPAVLIGGIGTLVVVALWIRLFPQLFHVDRLVD 406 SNQLGEFESG+ A G VP+V++GG+GTL+VVALW+RLFP L H DRL + Sbjct: 367 SNQLGEFESGMVAGMLGPVPSVVLGGLGTLLVVALWMRLFPALTHRDRLRE 417 >PA4622 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 403 Score = 427 bits (1099), Expect = e-119, Method: Compositional matrix adjust. Identities = 231/398 (58%), Positives = 285/398 (71%) Query: 7 PEQLLHHRSFRLFWLASVTSTIALQMQIVAVGWQVYQLTHSPFDLGIVGLVQFIPSLFLV 66 P LL HR F FWLA V + QM VA+GW +Y+LT + DLG+VGLV+F+P + + Sbjct: 5 PSSLLRHRPFLAFWLARVCTASGFQMLTVAIGWHIYELTGNVLDLGLVGLVEFLPRVLFM 64 Query: 67 FVVGHVADRHDRRQVARFSILVEAIAAGLLAAGSLGGWLTKEAIFAIVFVIGAGRAFSKP 126 GHVADR+DRR++A +A+ A L G+ G +T+ IF + F +G RAF P Sbjct: 65 LHTGHVADRYDRRRIAALCQAGQALVAVALVLGAASGEITRNMIFVLAFALGTARAFEMP 124 Query: 127 TMSAMLPTLMQPSLLPRAVAGSASATQVAIIIGPAIGGFLYVAGPSTVYITSCVLFVLCS 186 T A+LP L+ L PRAVA SASA Q A I PA+GG LY G S VY+ + L+VL Sbjct: 125 TTQALLPNLVPAGLFPRAVAASASAMQAATIAAPALGGLLYAFGASWVYVPTATLYVLAC 184 Query: 187 VLVSMIKVETPPARRENATLKSVFAGIAYIRSKPAIFGAISLDLFAVLLGGATALLPVYA 246 VL + V P + ATL S+ AGI +IRS+P IFGAISLDLFAVLLGGATALLPV+A Sbjct: 185 VLTLSLPVRNQPLTQGKATLDSLLAGIRFIRSRPDIFGAISLDLFAVLLGGATALLPVFA 244 Query: 247 HDILHTNSVGLGLLRSAPAVGALSVAIFLARNPLKGRIGRTMFIAVGIFGLATIAFGLSQ 306 DIL T GLGLLRSAPAVGAL+++ +LA ++ +GR MF++VGIFGLATIAFGLS+ Sbjct: 245 KDILLTGPWGLGLLRSAPAVGALAMSFWLAHFSIERNVGRIMFLSVGIFGLATIAFGLSK 304 Query: 307 TFVVSLLALVVLGASDMISVVVRSTFVQLETPDDMRGRVSAVNSVFIGTSNQLGEFESGL 366 +F +SL LVVLGA+DM+S+V+R FVQLETPD+MRGRVSAVN +FIG SNQLGEFESGL Sbjct: 305 SFWLSLGVLVVLGAADMVSMVIRGAFVQLETPDEMRGRVSAVNGLFIGASNQLGEFESGL 364 Query: 367 TAAWFGAVPAVLIGGIGTLVVVALWIRLFPQLFHVDRL 404 TA WFG VPAV++GGIGTLVV W++LFP L DRL Sbjct: 365 TAHWFGTVPAVVLGGIGTLVVTGAWMKLFPSLAQRDRL 402 >CAP0049 [GEPR] COG0477 Permeases of the major facilitator superfamily Cac Clostridium acetobutylicum Length = 408 Score = 419 bits (1077), Expect = e-117, Method: Compositional matrix adjust. Identities = 212/381 (55%), Positives = 272/381 (71%) Query: 22 ASVTSTIALQMQIVAVGWQVYQLTHSPFDLGIVGLVQFIPSLFLVFVVGHVADRHDRRQV 81 A V+S A QM VA+GWQ+Y LTHS F LG++GLVQF+P L L VGH++DR+DRR++ Sbjct: 21 ARVSSNFAYQMLTVAIGWQMYSLTHSAFYLGLIGLVQFLPMLVLSLFVGHISDRYDRRKI 80 Query: 82 ARFSILVEAIAAGLLAAGSLGGWLTKEAIFAIVFVIGAGRAFSKPTMSAMLPTLMQPSLL 141 S LV+ I LLA G+ GW+TKE+ +VF I +F P M A+LP +++ + Sbjct: 81 VSISQLVQGICIALLAFGNYNGWITKESFLIMVFFIALAHSFEGPPMQALLPNIVERKIF 140 Query: 142 PRAVAGSASATQVAIIIGPAIGGFLYVAGPSTVYITSCVLFVLCSVLVSMIKVETPPARR 201 P+A A +SA+Q A+I+GP G LY G S +Y + L +L SVL+ I V + Sbjct: 141 PKASALVSSASQFAVIVGPGFAGILYSFGASLIYSITAGLLILASVLIIQIHVNKEERKP 200 Query: 202 ENATLKSVFAGIAYIRSKPAIFGAISLDLFAVLLGGATALLPVYAHDILHTNSVGLGLLR 261 + LKS FAGI +I+S+P I GAISLDLFAVL GGATALLP+YA IL S GLG+LR Sbjct: 201 DPVNLKSFFAGITFIKSRPIILGAISLDLFAVLFGGATALLPIYASSILKIGSFGLGVLR 260 Query: 262 SAPAVGALSVAIFLARNPLKGRIGRTMFIAVGIFGLATIAFGLSQTFVVSLLALVVLGAS 321 SAPAVGAL ++ L R PLK +G+ MF AV FGL+TI F +S++ +VS LAL VLGAS Sbjct: 261 SAPAVGALLMSALLTRKPLKRNVGKIMFTAVVCFGLSTIIFAISKSVIVSFLALFVLGAS 320 Query: 322 DMISVVVRSTFVQLETPDDMRGRVSAVNSVFIGTSNQLGEFESGLTAAWFGAVPAVLIGG 381 D+ISVV+RST VQLETPD+MRGRVS+VN +FIGTSNQLGEFESG+TA+ G VPA L+GG Sbjct: 321 DVISVVIRSTLVQLETPDNMRGRVSSVNMIFIGTSNQLGEFESGITASLLGTVPAALLGG 380 Query: 382 IGTLVVVALWIRLFPQLFHVD 402 +GT++VV +W +LF LF VD Sbjct: 381 VGTILVVLIWRKLFSSLFTVD 401 >mlr4214 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 412 Score = 342 bits (877), Expect = 9e-94, Method: Compositional matrix adjust. Identities = 195/408 (47%), Positives = 256/408 (62%), Gaps = 4/408 (0%) Query: 1 MTS-AIAPEQ---LLHHRSFRLFWLASVTSTIALQMQIVAVGWQVYQLTHSPFDLGIVGL 56 MTS +PEQ H++F +W A +T A + VAVGWQ+Y LT PFDLGIVG+ Sbjct: 1 MTSLQTSPEQRYAAFRHKAFLSYWTARFLTTFATMVVSVAVGWQMYDLTRDPFDLGIVGI 60 Query: 57 VQFIPSLFLVFVVGHVADRHDRRQVARFSILVEAIAAGLLAAGSLGGWLTKEAIFAIVFV 116 VQF+PSL LV V G VADR RR + +++VEAI A L A +L IF ++ + Sbjct: 61 VQFLPSLLLVLVTGAVADRFGRRLIMALAVVVEAICALALLALTLRSISGPLPIFCVLAM 120 Query: 117 IGAGRAFSKPTMSAMLPTLMQPSLLPRAVAGSASATQVAIIIGPAIGGFLYVAGPSTVYI 176 G RAF P +++ L+ P A+A ++SA Q A I+GP GG LY P Y Sbjct: 121 FGVARAFFGPASASLFANLVPPEDFANAIAWNSSAWQTATIVGPVAGGLLYGVSPEVAYG 180 Query: 177 TSCVLFVLCSVLVSMIKVETPPARRENATLKSVFAGIAYIRSKPAIFGAISLDLFAVLLG 236 T+ VL + +L+ I E TL+++F G +YI S+ + GAISLDLFAVLL Sbjct: 181 TAAVLMLASGLLIFTIPKPAQRTETEKPTLQNLFGGFSYIWSEKIVLGAISLDLFAVLLS 240 Query: 237 GATALLPVYAHDILHTNSVGLGLLRSAPAVGALSVAIFLARNPLKGRIGRTMFIAVGIFG 296 GA+ALLPVYA DIL GLGLLRSAP++GA+ VA++LA +P++ G M A FG Sbjct: 241 GASALLPVYARDILQLGPWGLGLLRSAPSIGAICVAVWLAGHPMRNHAGMIMLAAAASFG 300 Query: 297 LATIAFGLSQTFVVSLLALVVLGASDMISVVVRSTFVQLETPDDMRGRVSAVNSVFIGTS 356 T+ FGLS +S+ ALV LGA+DM SV +R T +QL TPD++RGRV+AVN VF+G S Sbjct: 301 AFTVLFGLSTITWLSIAALVFLGATDMFSVYIRETLIQLWTPDEVRGRVNAVNQVFVGAS 360 Query: 357 NQLGEFESGLTAAWFGAVPAVLIGGIGTLVVVALWIRLFPQLFHVDRL 404 N++GEF +G AA G VPAV+IGG+G + V LW+ LFPQL V L Sbjct: 361 NEVGEFRAGTMAALIGTVPAVVIGGVGAIAVAGLWMVLFPQLRKVRHL 408 >SMc03237 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 415 Score = 338 bits (867), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 183/397 (46%), Positives = 258/397 (64%), Gaps = 6/397 (1%) Query: 11 LHHRSFRLFWLASVTSTIALQMQIVAVGWQVYQLTHSPFDLGIVGLVQFIPSLFLVFVVG 70 H +R ++ + + + A+Q+ VAVGWQ+Y LT PF LG++GL QF+PSL L+ V G Sbjct: 13 FRHVGYRRYFFSRLLAYFAVQIMSVAVGWQIYDLTRDPFSLGLIGLFQFLPSLVLILVTG 72 Query: 71 HVADRHDRRQVARFSILVEAIAAGLLAAGSLGGWLTKEAIFAIVFVIGAGRAFSKPTMSA 130 VADR++RR + +LV + L ++ G + ++AI+ V G RAF P + Sbjct: 73 SVADRYNRRAIMGICMLVSTLCGAALLLLTVTGLFSPWPVYAILVVFGIERAFLGPASQS 132 Query: 131 MLPTLMQPSLLPRAVAGSASATQVAIIIGPAIGGFLYVAGPSTVYITSCVLFVLCSVLVS 190 + P L+ LP A+A ++++ Q A+I+GP GG LY GP+ Y S F +++V Sbjct: 133 LAPNLVPAEDLPNAIAWNSTSWQTAMIVGPVAGGLLYGFGPTVPYAVSLGFFAAGALMVF 192 Query: 191 MIKVETPPARR---ENATLKSVFAGIAYIRSKPAIFGAISLDLFAVLLGGATALLPVYAH 247 + PARR A +++ AG YI+++ + GAISLDLFAVLLGGA AL+PV+A Sbjct: 193 AVP---KPARRSPPSAANWQTITAGFRYIKAEKIVLGAISLDLFAVLLGGAVALMPVFAR 249 Query: 248 DILHTNSVGLGLLRSAPAVGALSVAIFLARNPLKGRIGRTMFIAVGIFGLATIAFGLSQT 307 D+L GLGLLR+AP VGA+ +A++LA +P++ R G MF+ V +FGLAT+ FGLS T Sbjct: 250 DVLTLGPWGLGLLRAAPGVGAVGMAVWLAAHPIRNRAGLYMFVGVALFGLATVVFGLSAT 309 Query: 308 FVVSLLALVVLGASDMISVVVRSTFVQLETPDDMRGRVSAVNSVFIGTSNQLGEFESGLT 367 +S+ ALVV+GASDMISV VR + L TPD++RGRV+AVN VF+G SN+LGEF +G+ Sbjct: 310 PWISIAALVVMGASDMISVYVREILITLWTPDELRGRVNAVNMVFVGASNELGEFRAGMM 369 Query: 368 AAWFGAVPAVLIGGIGTLVVVALWIRLFPQLFHVDRL 404 A+ FG V AV+ GG GTL+V LW FPQL +D L Sbjct: 370 ASGFGTVFAVVFGGAGTLLVSLLWALGFPQLRRIDTL 406