BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0013.0020.p (430 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4343 [GEPR] COG0477 Permeases of the major facilitator superfa... 350 3e-96 RSp0536 [GEPR] COG0477 Permeases of the major facilitator superf... 328 1e-89 RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 286 8e-77 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 281 2e-75 PA5476 [GEPR] COG0477 Permeases of the major facilitator superfa... 278 1e-74 >PA4343 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 439 Score = 350 bits (899), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 190/403 (47%), Positives = 273/403 (67%), Gaps = 5/403 (1%) Query: 23 RAVISSSIGNALEWFDVLIYGAFAVIIAKLFFPTENETVSLLVTFATFGVSFFMRPLGAV 82 R V ++ IGNALEW+D ++YG + +IA+LFFP+ +E SLL+ ATFGV FFMRP+G V Sbjct: 12 RQVAAAVIGNALEWYDFIVYGFLSSLIARLFFPSGDEYTSLLMALATFGVGFFMRPVGGV 71 Query: 83 VLGAYSDRVGRKAALSLSIVLMTIGTAMIAFMPTYASIGLWAPAGIVLARLIQGFSAGGE 142 +LG Y+DR GRKAA+ L I+LMT+ AMIAF PTYA+IG+ AP IV+AR++QGF+ GGE Sbjct: 72 LLGLYADRRGRKAAMQLIILLMTLSIAMIAFAPTYAAIGVGAPLLIVIARMLQGFATGGE 131 Query: 143 FGSSTAFLVEHA-PHRRGFFSSWQVASQGLSLLMAAVFGAGLNGLLTPEQLYSWGWRLPF 201 + S+TAFLVE A PHRRG + SWQ+ Q L++ A GA + L E L SWGWR+PF Sbjct: 132 YASATAFLVESAPPHRRGLYGSWQLFGQCLAVFAGAGMGALVTHCLDAEALESWGWRVPF 191 Query: 202 LFGLLIGPAGYYIRRHLDESPEFAAAER---TETPLRDTFSSQKMRLLIGTGSVIMATVS 258 LFGLLIGP G +IRR++ E+ F A R L + +L+ G ++ TVS Sbjct: 192 LFGLLIGPVGLWIRRYMGETEAFLEAIREPGERQGLLGVLREYRRSVLVSMGLTVVGTVS 251 Query: 259 VYLALY-MPTYAIKQLGMPAWSSYAATIVSGLIMMVFSPLVGELSDKYGRTPFMIGSSLA 317 Y+ L MPT+A KQLG+P + + + +M + PL G LSD+ GR P ++ ++LA Sbjct: 252 FYVVLVNMPTFAHKQLGLPLDEVFMVQMAAVALMTLVIPLAGGLSDRVGRRPVLLVATLA 311 Query: 318 FVVFTYPMFVFLTSAPSFVNLLLLQIVIGVLMTMYFASMPALLADVFPVQTRGTGMSLSY 377 F++ YP+F ++ +APS LLL+Q+++ + +F P +A+ FPV+ R TG++++Y Sbjct: 312 FMLMVYPLFAWVAAAPSLGRLLLMQLLLCTAIGGFFGPAPTAVAEQFPVRVRSTGLAVAY 371 Query: 378 NIAVMLFGGFAGLIITWLIQFTGNKLSVSFFVIFGAALSLIAS 420 N+AVMLFGGFA I+TWL + G+ ++ +F+V+ A L L+A+ Sbjct: 372 NLAVMLFGGFAPFIVTWLTEVGGSPVAPAFYVLGAAFLGLLAT 414 >RSp0536 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 441 Score = 328 bits (841), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 190/423 (44%), Positives = 265/423 (62%), Gaps = 11/423 (2%) Query: 19 PQTWRAVISSSIGNALEWFDVLIYGAFAVIIAKLFFPTENETVSLLVTFATFGVSFFMRP 78 P+ AV ++ +GNA EWFD +YG FA +IA + FP+ N +LL+ ATFGV F RP Sbjct: 16 PRQRHAVATAILGNAFEWFDFTLYGFFAPVIATVLFPSANPFTALLLAIATFGVGFVTRP 75 Query: 79 LGAVVLGAYSDRVGRKAALSLSIVLMTIGTAMIAFMPTYASIGLWAPAGIVLARLIQGFS 138 LG +VLG Y+DR GR+ AL+LS +LM +GTA+IA PTYA G+ AP V+ARL+QGFS Sbjct: 76 LGGIVLGIYADRRGRRPALALSALLMALGTALIAIAPTYAQAGIAAPVIAVIARLLQGFS 135 Query: 139 AGGEFGSSTAFLVEHAPH-RRGFFSSWQVASQGLSLLMAAVFGAGLNGLLTPEQLYSWGW 197 AGGE G +TA+L E AP +R F++SW AS GL+++ A+ G LL E L +WGW Sbjct: 136 AGGEMGGATAYLNEIAPPGKRAFYTSWIQASVGLAIVCGAMLGTLATSLLDAEALRAWGW 195 Query: 198 RLPFLFGLLIGPAGYYIRRHLDESPEFAAA---ERTETPLRDTFSSQKMRLLIGTGSVIM 254 R+PF G+LIGP GY IR LDE+P FA A R ++PL + + +LIG VI+ Sbjct: 196 RIPFALGVLIGPIGYVIRSRLDETPAFARAATEARADSPLLEVVRRHRRAVLIGASIVIL 255 Query: 255 ATVSVYLAL-YMPTYAIKQLGMPAWSSYAATIVSGLIMMVFSPLVGELSDKYGRTPFMIG 313 TV Y+ L YM TYAI L +P+ + +A ++ SG+ MM+ +PL G L+D+ G + G Sbjct: 256 WTVCTYVLLFYMQTYAIHVLKLPSSAGFAGSMASGVTMMLTAPLFGWLADRLGYQRVLSG 315 Query: 314 SSLAFVVFTYPMFVFLTSAPSFVNLLLLQIVIGVLMTMYFASMPALLADVFPVQTRGTGM 373 ++LA +V YP++ +L AP+ L+ +QIV G+L Y +P AD+FP + TG+ Sbjct: 316 AALAILVLAYPLYAYLNHAPAAGTLIGVQIVFGLLSAAYTGPIPVAFADLFPTKVLSTGL 375 Query: 374 SLSYNIAVMLFGGFAGLIITWLIQFTGNKLSVSFFVIFGAALSLI------ASTAARYVL 427 S +YN+ VML GGFA +TWL L+ +V+ A +SLI A+ A R V Sbjct: 376 STAYNLTVMLIGGFAPFYLTWLSHAFDPMLAPVLYVMVAALVSLIGTLWLRAAAADRSVT 435 Query: 428 RVR 430 + R Sbjct: 436 QAR 438 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 286 bits (731), Expect = 8e-77, Method: Compositional matrix adjust. Identities = 169/405 (41%), Positives = 243/405 (60%), Gaps = 10/405 (2%) Query: 23 RAVISSSIGNALEWFDVLIYGAFAVIIAKLFFPTENETVSLLVTFATFGVSFFMRPLGAV 82 R++ GN LE +D ++YG +A IA FFP +NE +SL+++ TFGV F MRPLGA+ Sbjct: 12 RSIFRVVSGNFLEMYDFMVYGYYAKAIADTFFPADNEFLSLMLSLVTFGVGFLMRPLGAL 71 Query: 83 VLGAYSDRVGRKAALSLSIVLMTIGTAMIAFMPTYASIGLWAPAGIVLARLIQGFSAGGE 142 +LGAY DR GR+A L L++ LM GT +IA +P YA+IGL AP +++ RL+QGFSAG E Sbjct: 72 ILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIGRLLQGFSAGVE 131 Query: 143 FGSSTAFLVE-HAPHRRGFFSSWQVASQGLSLLMAAVFGAGLNGLLTPEQLYSWGWRLPF 201 G + +L E P R+GFF SWQ ASQ ++++ AA+ G L+ L+P+++ WGWR+PF Sbjct: 132 LGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPKEMGEWGWRVPF 191 Query: 202 LFGLLIGPAGYYIRRHLDESPEFAAAERTETP-LRDTFSS--QKMRLLIGTGS--VIMAT 256 L G LI P + IRR L E+ EF +R P L + F S + R L+G G+ V+M T Sbjct: 192 LVGCLIVPFLFLIRRSLQETEEF--KQRKHRPALGEIFRSMGENWR-LVGAGTLLVVMTT 248 Query: 257 VSVYL-ALYMPTYAIKQLGMPAWSSYAATIVSGLIMMVFSPLVGELSDKYGRTPFMIGSS 315 VS YL Y PT+ L + S T+ G + P++G +SD+ GR P +I + Sbjct: 249 VSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIGRRPLLITFT 308 Query: 316 LAFVVFTYPMFVFLTSAPSFVNLLLLQIVIGVLMTMYFASMPALLADVFPVQTRGTGMSL 375 ++ YP +L + PSF LL +++ + L Y +M L ++ P R TG SL Sbjct: 309 ALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPPAVRTTGFSL 368 Query: 376 SYNIAVMLFGGFAGLIITWLIQFTGNKLSVSFFVIFGAALSLIAS 420 +Y++A +FGGF I TWLI TGNK ++ F A L+A+ Sbjct: 369 AYSLATAIFGGFTPAIATWLIHATGNKAMPGLWLSFAAICGLVAT 413 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 281 bits (720), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 171/422 (40%), Positives = 248/422 (58%), Gaps = 14/422 (3%) Query: 4 ISSSNTGDAKSVKLHPQTWRAVISSSIGNALEWFDVLIYGAFAVIIAKLFFPTENETVSL 63 + + N ++K+ RA+ GN LE FD ++YG +A IA FFP N +SL Sbjct: 1 MHTHNPNESKA--------RAIFRVVSGNFLEMFDFMVYGYYATAIAATFFPAGNAFLSL 52 Query: 64 LVTFATFGVSFFMRPLGAVVLGAYSDRVGRKAALSLSIVLMTIGTAMIAFMPTYASIGLW 123 +++ TFG F MRPLGA+VLGAY DR GR+A L L++VLM GT +IA +P Y +IGL Sbjct: 53 MLSLMTFGAGFLMRPLGAIVLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLA 112 Query: 124 APAGIVLARLIQGFSAGGEFGSSTAFLVEHA-PHRRGFFSSWQVASQGLSLLMAAVFGAG 182 AP +++ RL+QGFSAGGE G + +L E A P R+GF+ SWQ SQ ++++ AA+ G Sbjct: 113 APLLVLIGRLLQGFSAGGEPGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVL 172 Query: 183 LNGLLTPEQLYSWGWRLPFLFGLLIGPAGYYIRRHLDESPEFAAAERTETPLRDTFSSQK 242 L+ L+P+++ WGWR+PFL G LI P ++IRR L E+ EF + T S + Sbjct: 173 LSFKLSPKEMGEWGWRVPFLIGCLIVPFLFFIRRSLRETEEFEQRKHRPTMGELLRSMGE 232 Query: 243 MRLLIGTGSV--IMATVSVYL-ALYMPTYAIKQLGMPAWSSYAATIVSGLIMMVFSPLVG 299 L G G++ +M TVS YL Y PT+ L M + S T+ G +++ P++G Sbjct: 233 NWRLAGAGTLLAVMTTVSFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMG 292 Query: 300 ELSDKYG-RTPFMIGSSLAFVVFTYPMFVFLTSAPSFVNLLLLQIVIGVLMTMYFASMPA 358 LSD+ G RTP ++ S+L + YP +L + PSF LL +++ + L Y +M Sbjct: 293 SLSDRIGRRTPLIVFSALTLLT-AYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIV 351 Query: 359 LLADVFPVQTRGTGMSLSYNIAVMLFGGFAGLIITWLIQFTGNKLSVSFFVIFGAALSLI 418 L ++ P Q R TG SL+Y++A +FGGF I T LI TGNK ++ F A L+ Sbjct: 352 TLTEIMPPQLRTTGFSLAYSLATAIFGGFTPAIATGLIHATGNKAMPGLWLSFAAICGLV 411 Query: 419 AS 420 A+ Sbjct: 412 AT 413 >PA5476 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 429 Score = 278 bits (712), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 163/378 (43%), Positives = 228/378 (60%), Gaps = 8/378 (2%) Query: 31 GNALEWFDVLIYGAFAVIIAKLFFPTENETVSLLVTFATFGVSFFMRPLGAVVLGAYSDR 90 GN LE +D ++YG +A IAK FFP +N SL+++ ATFG F MRPLGAV LGAY DR Sbjct: 17 GNFLEMYDFMVYGFYATAIAKTFFPGDNPFASLMLSLATFGAGFLMRPLGAVFLGAYIDR 76 Query: 91 VGRKAALSLSIVLMTIGTAMIAFMPTYASIGLWAPAGIVLARLIQGFSAGGEFGSSTAFL 150 GR+ L +++ LM +GT +IAF+P YA++G+ AP ++ RL+QGFSAG E G + +L Sbjct: 77 HGRRQGLIITLGLMAMGTLLIAFVPGYATLGVAAPLLVLFGRLLQGFSAGVELGGVSVYL 136 Query: 151 VEHA-PHRRGFFSSWQVASQGLSLLMAAVFGAGLNGLLTPEQLYSWGWRLPFLFGLLIGP 209 E A P R+GFF SWQ ASQ ++++ A + G LN L+P+ + WGWR+PF G LI P Sbjct: 137 SEIATPGRKGFFVSWQSASQQVAVVFAGLLGVLLNQWLSPQDMGEWGWRVPFFIGCLIVP 196 Query: 210 AGYYIRRHLDESPEFAAAERTETP-LRDTFSSQKMR---LLIGTGSVIMATVSVYL-ALY 264 A + IRR L+E+PEF A RT P L S +L GT V+M TVS YL Y Sbjct: 197 ALFVIRRSLEETPEFEA--RTHRPSLSQVLRSIGQNFGVVLAGTAMVVMTTVSFYLITAY 254 Query: 265 MPTYAIKQLGMPAWSSYAATIVSGLIMMVFSPLVGELSDKYGRTPFMIGSSLAFVVFTYP 324 PT+ +L + S T+ GL ++ P++G SD+ GR P ++G+S ++ YP Sbjct: 255 TPTFGKNELQLSDLDSLLVTMCIGLSNFIWLPVMGAFSDRIGRKPLLLGASALALLTAYP 314 Query: 325 MFVFLTSAPSFVNLLLLQIVIGVLMTMYFASMPALLADVFPVQTRGTGMSLSYNIAVMLF 384 +L PSF LL +++ + L + Y +M L +V P R TG SL+Y++A F Sbjct: 315 ALSWLVREPSFAGLLGVELWLSFLYSSYNGAMVVALTEVMPADVRTTGFSLAYSLATATF 374 Query: 385 GGFAGLIITWLIQFTGNK 402 GGF + TWLI N+ Sbjct: 375 GGFTPAVCTWLIHTLDNR 392