BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0136.p (454 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll8348 [GEPR] COG0477 Permeases of the major facilitator superf... 458 e-128 BMEII0596 [GEPR] COG0477 Permeases of the major facilitator supe... 435 e-121 SMc00813 [GEPR] COG0477 Permeases of the major facilitator super... 411 e-114 AGc1103 [GEPR] COG0477 Permeases of the major facilitator superf... 402 e-111 mll1728 [GEPR] COG0477 Permeases of the major facilitator superf... 330 4e-90 >mll8348 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 473 Score = 458 bits (1178), Expect = e-128, Method: Compositional matrix adjust. Identities = 237/445 (53%), Positives = 314/445 (70%), Gaps = 1/445 (0%) Query: 1 MEQMDSTVISTSLPVLAIDMAVDPISLKLALTSYLVSLAVFIPISGWMADRFGALTIFRS 60 ME MDSTVI+TSLP +AID+ PI+LKLALT+YLVSLA+FIPISGWMADRFGA IFR+ Sbjct: 15 MENMDSTVIATSLPAIAIDIHTSPIALKLALTAYLVSLAIFIPISGWMADRFGAKNIFRA 74 Query: 61 AICVFMLGSILCGVSQSLPEFVAARFFQGIGGAMMVPVGRLVILRSVDKANLVKALSYLT 120 AI VF++GS+ C +S SLP FV +RF QGIGGAMM PVGRLV++R+ K++LV A+S+LT Sbjct: 75 AIAVFIVGSVACALSGSLPAFVVSRFLQGIGGAMMTPVGRLVLVRATPKSDLVAAMSWLT 134 Query: 121 IPAMFGPVLGPPLGGFITTYFHWRWIFFINIPISILGLYLATRFIANAKSESVAPLDWVG 180 +PA+ GP++GPP+GGFITTYF W WIF IN+PI ++G++LATRF+ +S PLD++G Sbjct: 135 VPALVGPLVGPPIGGFITTYFTWHWIFLINVPIGLVGIWLATRFLPETESMETPPLDFIG 194 Query: 181 FVLSALGCSMVMMGLATTGRHLVSGDISLACVVLGSLSLAAYVWHARRTEHPLIDLKLLR 240 FVLS L S V+ GL+ + V +G LS A Y+ HARR ++PL+ L+L R Sbjct: 195 FVLSGLAASGVVFGLSVVSLPYLPPATGFITVGVGLLSGALYLMHARRAKNPLLALELFR 254 Query: 241 IETLQAGVGGGSLFRLGIGAIPFLLPLMLQLGFGFSAFHSGLLTCASAAGAMFMKTIAAK 300 + ++ V GGSLFR+GIGA+PFLLPLM Q+GFG + F SG++T SA GA+ MK + A Sbjct: 255 NQVFRSSVLGGSLFRIGIGAVPFLLPLMFQIGFGLTPFQSGMITFVSAVGAIGMKFVTAL 314 Query: 301 FLKRYGFRRVMIVNGACGVMSLAAIGFFTPATPYAVMLIVLLIGGCFRSLQFTSLNAISY 360 + GFRRV+I+ S+A G FTP TPY +ML +LL+GG RS+ FT +NA+SY Sbjct: 315 IFRVAGFRRVLIIGSLVAAASIAIYGLFTPETPYVLMLAILLVGGFIRSMFFTGVNALSY 374 Query: 361 ADVDNNRLSQATSIASVAQQLSVGMGVVLGGFALQMSNHIQGHATLVSQDFWPAFLTVAV 420 A+V S+AT I +V QQLS+ +GV L G L++S I G L+ DF AF VA Sbjct: 375 AEVSAEDTSKATPITAVFQQLSIALGVALAGGILEVSTSIHG-GPLMLGDFHIAFFIVAA 433 Query: 421 AASFSIPLLMRLPPDAGAELAGRNQ 445 ++ + MRL PDAG ++G + Sbjct: 434 VSAAASLSFMRLAPDAGNAVSGHGR 458 >BMEII0596 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 469 Score = 435 bits (1118), Expect = e-121, Method: Compositional matrix adjust. Identities = 226/441 (51%), Positives = 298/441 (67%), Gaps = 1/441 (0%) Query: 1 MEQMDSTVISTSLPVLAIDMAVDPISLKLALTSYLVSLAVFIPISGWMADRFGALTIFRS 60 MEQMDS VISTSLP +A D+ PI+LKLALT+YLV+LAVFIP+SGWMADRFGA +FR+ Sbjct: 15 MEQMDSNVISTSLPAIAADIGTSPIALKLALTAYLVALAVFIPVSGWMADRFGAKNVFRA 74 Query: 61 AICVFMLGSILCGVSQSLPEFVAARFFQGIGGAMMVPVGRLVILRSVDKANLVKALSYLT 120 AI VF++GSI C S SLP FV ARF QG+GGAMM PVGRLV++RS + LV A+++LT Sbjct: 75 AIAVFVVGSIACAASNSLPAFVIARFLQGMGGAMMTPVGRLVLIRSTPRNELVSAMAWLT 134 Query: 121 IPAMFGPVLGPPLGGFITTYFHWRWIFFINIPISILGLYLATRFIANAKSESVAPLDWVG 180 IPAM GP++GPP+GGFITT+ W WIF IN+PI ++G++ AT F+ + + + LDW G Sbjct: 135 IPAMVGPLVGPPVGGFITTFLTWHWIFLINVPIGMIGIWFATHFLPDNEERIIKRLDWPG 194 Query: 181 FVLSALGCSMVMMGLATTGRHLVSGDISLACVVLGSLSLAAYVWHARRTEHPLIDLKLLR 240 F LS S V+ GL+ + I A + +G L YV HARRT PL++L+L Sbjct: 195 FFLSGFAMSGVVFGLSVVSLPALPPVIGFATLAVGMLCTVLYVLHARRTPDPLLNLRLFD 254 Query: 241 IETLQAGVGGGSLFRLGIGAIPFLLPLMLQLGFGFSAFHSGLLTCASAAGAMFMKTIAAK 300 + ++ V GGS+FR GIGAIPFLLPLM QLGFG + F SG++T SA GA+ MK A + Sbjct: 255 NQVFRSAVFGGSIFRFGIGAIPFLLPLMFQLGFGLTPFQSGMMTFVSAIGAISMKFGAKR 314 Query: 301 FLKRYGFRRVMIVNGACGVMSLAAIGFFTPATPYAVMLIVLLIGGCFRSLQFTSLNAISY 360 R FRR ++ +A G FTPATPY +++ LL+GG RSL FT +NA+++ Sbjct: 315 IFTRISFRRALMGGSLISAAFIAVNGTFTPATPYWIIIGFLLVGGFARSLFFTGVNALAF 374 Query: 361 ADVDNNRLSQATSIASVAQQLSVGMGVVLGGFALQMSNHIQGHATLVSQDFWPAFLTVAV 420 A++ N + SQAT + +VAQQ+S+ +GV L G L++S ++G A L DF F VA Sbjct: 375 AEIPNEKTSQATPLTAVAQQVSIAIGVALAGGILEISTMLRG-APLALVDFHIGFFVVAC 433 Query: 421 AASFSIPLLMRLPPDAGAELA 441 + + RL PDAG ELA Sbjct: 434 VSVLAFFWFARLAPDAGKELA 454 >SMc00813 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 470 Score = 411 bits (1057), Expect = e-114, Method: Compositional matrix adjust. Identities = 213/446 (47%), Positives = 299/446 (67%), Gaps = 1/446 (0%) Query: 1 MEQMDSTVISTSLPVLAIDMAVDPISLKLALTSYLVSLAVFIPISGWMADRFGALTIFRS 60 MEQMDSTVISTSLP +A DM V PI+LKLALTSY+V+LA+FIP+SGWMADRFGA IFR+ Sbjct: 15 MEQMDSTVISTSLPAIARDMGVGPITLKLALTSYMVALAIFIPLSGWMADRFGAKRIFRA 74 Query: 61 AICVFMLGSILCGVSQSLPEFVAARFFQGIGGAMMVPVGRLVILRSVDKANLVKALSYLT 120 AI VF+ GS+ C V+ SL FV ARF QG+GGAMM PV RLV++RS ++ LV A++ LT Sbjct: 75 AILVFIAGSVFCAVADSLFAFVVARFLQGMGGAMMTPVARLVLVRSAPRSELVSAMALLT 134 Query: 121 IPAMFGPVLGPPLGGFITTYFHWRWIFFINIPISILGLYLATRFIANAKSESVAPLDWVG 180 IPA+ GP+ GPPLGGFITTYF W WIF IN+P+ I+G +L+ ++ + + P+D +G Sbjct: 135 IPALVGPLAGPPLGGFITTYFSWHWIFLINVPVGIVGYFLSGIYLPEMERRNPPPVDIIG 194 Query: 181 FVLSALGCSMVMMGLATTGRHLVSGDISLACVVLGSLSLAAYVWHARRTEHPLIDLKLLR 240 F+L + + V+ GL+ + I +A V G + Y++HARR P++DLKL R Sbjct: 195 FLLGGIAAAGVVFGLSVISLPALPPAIGIASVSAGVAASLLYIFHARRHPAPVLDLKLFR 254 Query: 241 IETLQAGVGGGSLFRLGIGAIPFLLPLMLQLGFGFSAFHSGLLTCASAAGAMFMKTIAAK 300 +A GG++FR+ +GA+PFL+PLMLQ+GFG S F SGL+T A GA+ K +A + Sbjct: 255 DGAFRAASIGGTIFRISVGAVPFLMPLMLQVGFGLSPFQSGLITFVGAVGAITTKFLARR 314 Query: 301 FLKRYGFRRVMIVNGACGVMSLAAIGFFTPATPYAVMLIVLLIGGCFRSLQFTSLNAISY 360 GFR +++ ++ A GFFTPATPY +++ VLLI G RS FT +NA+S+ Sbjct: 315 VFAFAGFRTTLLIAAVIAAVTTFANGFFTPATPYLLLISVLLIAGFARSFFFTGVNALSF 374 Query: 361 ADVDNNRLSQATSIASVAQQLSVGMGVVLGGFALQMSNHIQGHATLVSQDFWPAFLTVAV 420 AD+D+ S+ATS+++V QQ+S+ +GV + G L+ + G L DF AF+ +A+ Sbjct: 375 ADIDDADASKATSMSAVLQQISLALGVAVAGAILEFETALSGK-PLELADFHVAFMIIAI 433 Query: 421 AASFSIPLLMRLPPDAGAELAGRNQA 446 A + + + +AGA ++G A Sbjct: 434 ANLLAAIPFIAMAKNAGASVSGHRLA 459 >AGc1103 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 475 Score = 402 bits (1032), Expect = e-111, Method: Compositional matrix adjust. Identities = 213/445 (47%), Positives = 303/445 (68%), Gaps = 3/445 (0%) Query: 1 MEQMDSTVISTSLPVLAIDMAVDPISLKLALTSYLVSLAVFIPISGWMADRFGALTIFRS 60 MEQMDSTVI+TSLP +A D+ V PI+LKLALT+Y+V+LA+FIPISGWMAD++GA IFR Sbjct: 25 MEQMDSTVIATSLPAIAKDLHVGPITLKLALTAYMVALAIFIPISGWMADKYGAKKIFRI 84 Query: 61 AICVFMLGSILCGVSQSLPEFVAARFFQGIGGAMMVPVGRLVILRSVDKANLVKALSYLT 120 AI VF++GSI C VS S+ EFV +RF QG+GGAMM PVGRLV+LR+ ++ LV A++ LT Sbjct: 85 AIGVFVVGSICCAVSSSVFEFVLSRFLQGMGGAMMTPVGRLVLLRTTKRSELVSAMALLT 144 Query: 121 IPAMFGPVLGPPLGGFITTYFHWRWIFFINIPISILGLYLATRFIANAKSESVAPLDWVG 180 IP + GP+ GPP+GGFITTYF W WIF IN+PI I+G++L+T F+ ++ + P+D G Sbjct: 145 IPGLVGPLTGPPIGGFITTYFSWHWIFLINVPIGIIGIWLSTIFLPEIETTNPPPMDGKG 204 Query: 181 FVLSALGCSMVMMGLATTGRHLVSGDISLACVVLGSLSLAAYVWHARRTEHPLIDLKLLR 240 F+LS + S V+ G++ + I +A V+G + Y+ HA R P++D ++ + Sbjct: 205 FILSGIAASGVVFGVSVVSLPALPPAIGIASTVIGFICGFLYMRHAARHPAPILDFRIFQ 264 Query: 241 IETLQAGVGGGSLFRLGIGAIPFLLPLMLQLGFGFSAFHSGLLTCASAAGAMFMKTIAAK 300 T +A GG++FR+ GAIPFL+PLMLQ+GFG + F SG++T A A GA+ K +A + Sbjct: 265 NATFRAASVGGTVFRISTGAIPFLMPLMLQIGFGLNPFQSGMITFAGAIGAITTKFMAKR 324 Query: 301 FLKRYGFRRVMIVNGACGVMSLAAIGFFTPATPYAVMLIVLLIGGCFRSLQFTSLNAISY 360 GFR +I G G + A FFTP TPY +++I L+ G RS FT NA+SY Sbjct: 325 VFAATGFRSTLIGAGIVGAFTTLANSFFTPETPYPLIMIFLVTAGFARSFFFTGSNALSY 384 Query: 361 ADVDNNRLSQATSIASVAQQLSVGMGVVLGGFALQMSNHIQG-HATLVSQDFWPAFLTVA 419 +D+++++ SQATS+ASV QQ+S+ +GV L++S+ + G H L DF AF VA Sbjct: 385 SDIEDSQASQATSMASVLQQISLALGVAFAASILEVSSMMSGTHLQLA--DFHIAFTIVA 442 Query: 420 VAASFSIPLLMRLPPDAGAELAGRN 444 + + F+I ++R+ AGA ++G Sbjct: 443 LVSLFAIVPIIRMDAQAGAAVSGHR 467 >mll1728 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 477 Score = 330 bits (846), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 189/449 (42%), Positives = 281/449 (62%), Gaps = 11/449 (2%) Query: 1 MEQMDSTVISTSLPVLAIDMAVDPISLKLALTSYLVSLAVFIPISGWMADRFGALTIFRS 60 M+ +DST+ISTSLP + V +++ + +T Y++++AVF+P+SGW+ADRFGA IF Sbjct: 30 MQLLDSTIISTSLPQMGQSYGVPAVAMSVGITVYMLTMAVFVPLSGWLADRFGARNIFLV 89 Query: 61 AICVFMLGSILCGVSQSLPEFVAARFFQGIGGAMMVPVGRLVILRSVDKANLVKALSYLT 120 AI +F L S+ CG SQ+L +FVAAR QG+G A+M PVGR+++LR+ K+ L+ A + +T Sbjct: 90 AIALFTLASLACGFSQNLTQFVAARAVQGLGSALMTPVGRILVLRNASKSELLNATALIT 149 Query: 121 IPAMFGPVLGPPLGGFITTYFHWRWIFFINIPISILGLYLATRFIANAKSESVAPLDWVG 180 PA+F PV+GP LGGFITT W W FFINIP+ ++GL L RFI + + PLDW G Sbjct: 150 WPALFAPVVGPVLGGFITTTLSWHWNFFINIPLGLIGLALVARFIPGDRVANPKPLDWPG 209 Query: 181 FVLSALGCSMVMMGLATTGRHLVSGDISL-----ACVVLGSLSLAAYVWHARRTEHPLID 235 F L++LG + ++ GL H G + A +V+G L+ V H RR HPL+D Sbjct: 210 FFLTSLGLACLLYGLERIA-HPEDGMLPTVLLIAAGIVIGWLA----VRHLRRAPHPLLD 264 Query: 236 LKLLRIETLQ-AGVGGGSLFRLGIGAIPFLLPLMLQLGFGFSAFHSGLLTCASAAGAMFM 294 L ++ T + + G++FR+ I A PFLLPL+ QLGFG S +GL+ A G + M Sbjct: 265 LSSFKVLTFAISTLAAGTIFRVAINATPFLLPLLFQLGFGLSPVDAGLMILAYFVGNLGM 324 Query: 295 KTIAAKFLKRYGFRRVMIVNGACGVMSLAAIGFFTPATPYAVMLIVLLIGGCFRSLQFTS 354 KT+ L+R+GFR VM+VNG S+ A G +P TP A++++++LI G RS+QFT+ Sbjct: 325 KTVTTPTLRRFGFRSVMVVNGIIASASIMACGVISPQTPQALVVVLMLIAGLSRSMQFTA 384 Query: 355 LNAISYADVDNNRLSQATSIASVAQQLSVGMGVVLGGFALQMSNHIQGHATLVSQDFWPA 414 LN +++AD+D R S A +++S+ QQ+++ GV + L +S + +L DF A Sbjct: 385 LNTLAFADIDAARRSSAATLSSMLQQVAMLFGVAVAAAILNLSQIARAQPSLDLVDFRIA 444 Query: 415 FLTVAVAASFSIPLLMRLPPDAGAELAGR 443 F + + + LP AGAE++G Sbjct: 445 FFVIGAIGLVAALRFLVLPRAAGAEVSGH 473