BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0135.p (299 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4287 [GER] COG0697 Permeases of the drug/metabolite transporte... 267 2e-71 YPO2761 [GER] COG0697 Permeases of the drug/metabolite transport... 261 9e-70 AGpA485 [GER] COG0697 Permeases of the drug/metabolite transport... 260 2e-69 RSp1638 [GER] COG0697 Permeases of the drug/metabolite transport... 255 1e-67 AGc4446 [GER] COG0697 Permeases of the drug/metabolite transport... 125 1e-28 >PA4287 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 296 Score = 267 bits (683), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 149/287 (51%), Positives = 203/287 (70%) Query: 10 VFPISAILIWSGNTIVSKMAAGVIEPAAMSFYRWLMAGLLLTPFCLRGVWRQRHQIRPHL 69 +FP+ A+ IW+GNT+V+K+A G+I+PA + F+RWL+ GL LTPF L V R R I +L Sbjct: 4 LFPLLAVFIWAGNTVVNKLAVGIIQPAEIGFFRWLLVGLALTPFMLGPVLRNRRYILANL 63 Query: 70 WKVVVLALFGMVLYQSLAYFAAATSSATSMGMIASLMPLLTLLLSSILLREPPTWGTLFG 129 K VVL L GM +YQSLAY+AAA +SAT+MG+I SLMPL++L L+S +L G L G Sbjct: 64 GKFVVLGLLGMAVYQSLAYYAAALTSATNMGIILSLMPLMSLGLASSILAHRLNAGALLG 123 Query: 130 GMLSLFGLAILIGKGHPAQLFTSGVVFGDLLMLVATIAYAFYSVLLKRWALPIATWHLLY 189 ++SL G+ ++I +GH L GV GD +M+VAT+AYA YSVLLK+W+L + LLY Sbjct: 124 ALVSLAGVVLVISQGHLGALLEHGVNLGDAMMIVATLAYAVYSVLLKKWSLKLPAMQLLY 183 Query: 190 LQIWVAVILLLPLCLAAPYSPVTAANLPLLLYAGIAASIISQVLWMNGVAHLGATHSIMF 249 LQ+ VA++ LLPL L +P + + AANLPL+LYA + ASI++ + WM+GVA LG + +F Sbjct: 184 LQVLVAILALLPLYLLSPRTGLNAANLPLVLYAALFASIVAALAWMHGVARLGPSRMALF 243 Query: 250 MNLSPIFTVIIAMVVLDEALHSYHAVGGGITLAGVVLAQLIKRRIVR 296 NL PI T IA +VL E L +H VGG +TLAGV+LA+ +RR R Sbjct: 244 FNLLPIITACIATLVLGERLTVHHLVGGALTLAGVLLAEFWQRRPAR 290 >YPO2761 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ype Yersinia pestis Length = 305 Score = 261 bits (668), Expect = 9e-70, Method: Compositional matrix adjust. Identities = 155/286 (54%), Positives = 206/286 (72%) Query: 11 FPISAILIWSGNTIVSKMAAGVIEPAAMSFYRWLMAGLLLTPFCLRGVWRQRHQIRPHLW 70 FP+ A++IWS N +VSK++A I+PAA+SFYRWL+A L L+PF L GV R IR + W Sbjct: 5 FPLFAVIIWSVNAVVSKISATAIDPAAISFYRWLLALLTLSPFLLLGVVRNWQAIRVYWW 64 Query: 71 KVVVLALFGMVLYQSLAYFAAATSSATSMGMIASLMPLLTLLLSSILLREPPTWGTLFGG 130 K+++L + GMVLYQSLAY+AA + SA MG+++SL+PLLT+L+S +LLR PT G G Sbjct: 65 KLMLLGMLGMVLYQSLAYYAAHSVSALFMGILSSLIPLLTVLISIVLLRVAPTVGIALGS 124 Query: 131 MLSLFGLAILIGKGHPAQLFTSGVVFGDLLMLVATIAYAFYSVLLKRWALPIATWHLLYL 190 +LSL GL LI G+P QL G+ G+L+ML A+ +YA Y VL KRWA+ + W LY+ Sbjct: 125 LLSLGGLVWLISAGNPVQLLQHGIGKGELMMLGASASYALYGVLTKRWAIQLPNWQSLYM 184 Query: 191 QIWVAVILLLPLCLAAPYSPVTAANLPLLLYAGIAASIISQVLWMNGVAHLGATHSIMFM 250 QI V+LLLP L P +TA N+PL+L+AGI ASI++ LW+ GV LGA + +FM Sbjct: 185 QIVFGVVLLLPGFLMTPDVQLTAQNIPLVLFAGIPASILAPYLWIQGVMRLGANTASIFM 244 Query: 251 NLSPIFTVIIAMVVLDEALHSYHAVGGGITLAGVVLAQLIKRRIVR 296 NL+P+FT IIA+V L E LHSYH +GGGITLAGVVLAQ ++ + R Sbjct: 245 NLTPVFTAIIAVVFLHEQLHSYHLIGGGITLAGVVLAQRLRSPLRR 290 >AGpA485 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 309 Score = 260 bits (665), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 139/287 (48%), Positives = 200/287 (69%) Query: 2 AHMQLKYSVFPISAILIWSGNTIVSKMAAGVIEPAAMSFYRWLMAGLLLTPFCLRGVWRQ 61 A M +KY +F + A+LIW GNTIVSK+AAG I P ++F RW +A ++LTP R WR Sbjct: 5 APMPVKYLLFSLLAVLIWVGNTIVSKLAAGAIAPGTIAFERWFIAFVILTPLVYRDAWRH 64 Query: 62 RHQIRPHLWKVVVLALFGMVLYQSLAYFAAATSSATSMGMIASLMPLLTLLLSSILLREP 121 R I HL K+++L L GM Q L Y+AA ++AT+M ++ SL+PLLTL+LS++ L E Sbjct: 65 RRTIAAHLPKLILLGLLGMAACQGLGYYAAGLTTATNMAIMLSLVPLLTLILSAVFLAER 124 Query: 122 PTWGTLFGGMLSLFGLAILIGKGHPAQLFTSGVVFGDLLMLVATIAYAFYSVLLKRWALP 181 P+ + GG++SL G+ I++G+G P++L + GV GD +ML A +AYA Y +LL+RWA+P Sbjct: 125 PSSLAVIGGIISLSGIFIVLGQGDPSRLLSQGVGRGDAMMLAAVLAYAGYGILLRRWAIP 184 Query: 182 IATWHLLYLQIWVAVILLLPLCLAAPYSPVTAANLPLLLYAGIAASIISQVLWMNGVAHL 241 +ATW +Y+QI AV+LL+P L + S +T N ++LYA I SI++ +WM V HL Sbjct: 185 LATWTSIYVQIGAAVVLLVPSYLLSAPSALTLPNTAMVLYAAIPGSILAPFVWMTAVKHL 244 Query: 242 GATHSIMFMNLSPIFTVIIAMVVLDEALHSYHAVGGGITLAGVVLAQ 288 GA + +FMNL PIFT I+A + L EAL+ YH +GGG+T+AG++L Q Sbjct: 245 GAARTAIFMNLIPIFTAIVAAIFLGEALYIYHLLGGGMTVAGIILVQ 291 >RSp1638 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 297 Score = 255 bits (651), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 128/278 (46%), Positives = 195/278 (70%) Query: 11 FPISAILIWSGNTIVSKMAAGVIEPAAMSFYRWLMAGLLLTPFCLRGVWRQRHQIRPHLW 70 +P+ A+L+W+ NTIVSK AAGV++PAA+S YRW++A +LTPF R +WRQR + P L Sbjct: 5 YPLLAVLVWAANTIVSKAAAGVLDPAAISLYRWVIAAAVLTPFWARPLWRQRRDVLPWLP 64 Query: 71 KVVVLALFGMVLYQSLAYFAAATSSATSMGMIASLMPLLTLLLSSILLREPPTWGTLFGG 130 ++ VLAL G+V+YQ L+Y+AA ++SAT++G+I +L+P+L L+++ ++ R+P + G Sbjct: 65 RLSVLALLGLVMYQCLSYYAAYSTSATNIGVICALIPMLGLIINGVVFRQPVGAPAVAGI 124 Query: 131 MLSLFGLAILIGKGHPAQLFTSGVVFGDLLMLVATIAYAFYSVLLKRWALPIATWHLLYL 190 +SL G+ L+G+GHPA LF GV GD+L+L+ + AYA Y++L +RWA P W LYL Sbjct: 125 AVSLLGVLYLLGRGHPASLFDGGVNRGDVLVLIGSAAYALYNILYRRWAPPFGQWLNLYL 184 Query: 191 QIWVAVILLLPLCLAAPYSPVTAANLPLLLYAGIAASIISQVLWMNGVAHLGATHSIMFM 250 Q +AV++LLPL A + + ++L+AGI ASI++ WM G+A LG+ +++ M Sbjct: 185 QALLAVVMLLPLAFTARSLAIPQQGIGMVLFAGIGASIVAMYWWMLGLARLGSERTVVMM 244 Query: 251 NLSPIFTVIIAMVVLDEALHSYHAVGGGITLAGVVLAQ 288 NL P+FT ++A +L E +H YH +GGG+ L GV L Q Sbjct: 245 NLLPVFTALMASAMLGETIHGYHWIGGGLILLGVSLVQ 282 >AGc4446 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 302 Score = 125 bits (314), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 88/288 (30%), Positives = 154/288 (53%), Gaps = 15/288 (5%) Query: 13 ISAILIWSGNTIVSKMAAGVIEPAAMSFYRWLMAGLLLTPFCLRGVWRQRHQIRPHLWKV 72 I A L W GNT+ K+A G I P A +F RW++A ++ + + + ++ L Sbjct: 17 IIATLCWGGNTVAGKLAVGHISPMAFTFLRWVLAVAIIFAISVPQLIKDWPVVKQRLPYF 76 Query: 73 VVLALFGMVLYQSLAYFAAATSSATSMGMIASLMPLLTLLLSSILLREPPTWGTLFGGML 132 VL G + Y A +SA + +I + +P++ +L+ +L R +G + G L Sbjct: 77 FVLGSVGYTAFNVFLYTALQHTSAINAAVIQAGIPMVIFVLNFVLFRTRVLFGQIAGFCL 136 Query: 133 SLFGLAILIGKGHPAQLFTSGVVFGDLLMLVATIAYAFYSVLLKRWALPIATWH-LLYLQ 191 ++ G+A+L G P L + GD +ML+A + YA Y+V+L RW P W L+ + Sbjct: 137 TISGVALLASHGDPLSLLQLEMNVGDAVMLLAVLVYAIYTVIL-RWK-PAVDWRTLMAIP 194 Query: 192 IWVAVILLLPLCLAAPYSPVTAANL--------PLLLYAGIAASIISQVLWMNGVAHLGA 243 + A++ +PL + ++ +L L++YAGI AS+I+Q+L++ GV +GA Sbjct: 195 AFFALLTSVPLV----FFEMSRESLIWPDQKGWMLVVYAGIFASLIAQILYIKGVEQIGA 250 Query: 244 THSIMFMNLSPIFTVIIAMVVLDEALHSYHAVGGGITLAGVVLAQLIK 291 + +F+NL P+F ++++ VL E LH+Y + LAG+ +A+ K Sbjct: 251 NRAGLFINLVPVFGTLLSVFVLSETLHTYQIAALFMALAGIAVAERKK 298