BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0124.p (176 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ydbS [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Eco Esc... 189 2e-48 BMEII1021 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bm... 153 2e-37 PA3591 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae P... 151 6e-37 PA1629 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae P... 150 1e-36 BMEII0214 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bm... 148 6e-36 >ydbS [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Eco Escherichia coli K12 Length = 255 Score = 189 bits (480), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 100/190 (52%), Positives = 128/190 (67%), Gaps = 16/190 (8%) Query: 1 MAQTDAIGALLDVRPQYWKAIAGFSKPLLAAVNGYALGAGCEMLMHADIAIAGRGAKIGQ 60 MA+ D L D RPQ W + F+KPL+AAVNGYALGAGCE+ + D+ +AG A+ G Sbjct: 68 MAEKDLAATLNDTRPQLWARLQAFNKPLIAAVNGYALGAGCELALLCDVVVAGENARFGL 127 Query: 61 PEINLGTIPGAGGTQRLIRTVGKPLAMKMVLSGEFLSADDALSAGLIAA----------- 109 PEI LG +PGAGGTQRLIR+VGK LA KMVLSGE ++A A AGL++ Sbjct: 128 PEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSDVFPSDLTLEYA 187 Query: 110 ---AAGQGSHAQVPLALRLAKEAMLKSYELGLEAGLNLERKSFSLLAASEDRREGIAAFK 166 A+ H+ PLAL+ AK+A+ +S E+ L+AGL ER+ F+LLAA+EDR EGI+AF Sbjct: 188 LQLASKMARHS--PLALQAAKQALRQSQEVALQAGLAQERQLFTLLAATEDRHEGISAFL 245 Query: 167 EKRTAQFVGR 176 +KRT F GR Sbjct: 246 QKRTPDFKGR 255 >BMEII1021 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bme Brucella melitensis Length = 261 Score = 153 bits (386), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 87/171 (50%), Positives = 112/171 (65%), Gaps = 12/171 (7%) Query: 18 WKAIAGFSKPLLAAVNGYALGAGCEMLMHADIAIAGRGAKIGQPEINLGTIPGAGGTQRL 77 W AIA +KP++AAVNGYALG GCE+ MH DI +AG GA GQPE+ LG +PGAGGTQRL Sbjct: 91 WDAIASCAKPVIAAVNGYALGGGCELAMHCDIIVAGEGAVFGQPEVKLGLMPGAGGTQRL 150 Query: 78 IRTVGKPLAMKMVLSGEFLSADDALSAGLIAAAAGQG-----SH------AQVP-LALRL 125 IR VGK AM++ L+G + A +ALS G+I+ +H A++P LA+ Sbjct: 151 IRAVGKFQAMRIALTGCMVPAAEALSIGMISEMTANERTLPRAHELAVEIARLPALAVAQ 210 Query: 126 AKEAMLKSYELGLEAGLNLERKSFSLLAASEDRREGIAAFKEKRTAQFVGR 176 KE ML +L L+ L LERK+F LL S+D++EG AAF EKR + GR Sbjct: 211 IKEVMLVGADLPLDGALALERKAFQLLFDSKDQKEGAAAFLEKRKPAYNGR 261 >PA3591 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae Pseudomonas aeruginosa Length = 265 Score = 151 bits (382), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 80/173 (46%), Positives = 114/173 (65%), Gaps = 12/173 (6%) Query: 16 QYWKAIAGFSKPLLAAVNGYALGAGCEMLMHADIAIAGRGAKIGQPEINLGTIPGAGGTQ 75 ++W+A+A KPL+AAV G+ALG GCE+ MH D+ +AG A+ QPEI +G +PGAGGTQ Sbjct: 93 RHWQALAACRKPLIAAVEGHALGGGCELAMHCDLIVAGASARFAQPEIRVGVMPGAGGTQ 152 Query: 76 RLIRTVGKPLAMKMVLSGEFLSADDALSAGLIAAAAGQGS--------HAQV----PLAL 123 RL+R VGK A++M+ +G + A +AL+ GL++ A G Q+ PLAL Sbjct: 153 RLVRAVGKFQALRMLFTGCTVRAPEALAIGLVSEVAADGQALDRALELARQIAGLPPLAL 212 Query: 124 RLAKEAMLKSYELGLEAGLNLERKSFSLLAASEDRREGIAAFKEKRTAQFVGR 176 KE +L +L L+ L LERK+F LL S D++EG+ AF EKRTA+++G+ Sbjct: 213 AQIKEVVLAGADLPLDQALALERKAFQLLFDSHDQKEGMRAFLEKRTAEYLGK 265 >PA1629 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae Pseudomonas aeruginosa Length = 261 Score = 150 bits (380), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 79/173 (45%), Positives = 113/173 (65%), Gaps = 12/173 (6%) Query: 16 QYWKAIAGFSKPLLAAVNGYALGAGCEMLMHADIAIAGRGAKIGQPEINLGTIPGAGGTQ 75 +YW+AIA KP++AAVNG+ALG GCE+ MH D+ +AG A+ QPEI +G +PGAGGTQ Sbjct: 89 RYWEAIARCPKPVIAAVNGFALGGGCELAMHCDLIVAGESAQFAQPEIKVGVMPGAGGTQ 148 Query: 76 RLIRTVGKPLAMKMVLSGEFLSADDALSAGLIA-AAAGQGSHAQV-----------PLAL 123 RL+R VGK A++M+ +G + A AL+ GL++ A + + A+ PLAL Sbjct: 149 RLVRAVGKFQALRMLFTGCLVKAPQALAMGLVSEVVADESTLARALELAMEIARLPPLAL 208 Query: 124 RLAKEAMLKSYELGLEAGLNLERKSFSLLAASEDRREGIAAFKEKRTAQFVGR 176 KE +L +L L++ L LERK+F LL S+D++EG+ AF EKR + G+ Sbjct: 209 AQIKEVVLAGADLPLDSALALERKAFQLLFDSQDQKEGMHAFLEKRPPNYQGK 261 >BMEII0214 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bme Brucella melitensis Length = 297 Score = 148 bits (374), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 90/189 (47%), Positives = 118/189 (62%), Gaps = 14/189 (7%) Query: 1 MAQTDAIGALLDVR-PQYWKAIAGFSKPLLAAVNGYALGAGCEMLMHADIAIAGRGAKIG 59 AQT A G+LL R +YW+++A KP++AAV GYALG GCE+ MHADI +A R A G Sbjct: 110 FAQTGA-GSLLAQRMHRYWESLAHCPKPVIAAVEGYALGGGCELAMHADIIVAARTASFG 168 Query: 60 QPEINLGTIPGAGGTQRLIRTVGKPLAMKMVLSGEFLSADDALSAGLIA--AAAGQGSHA 117 QPEI LG +PGAGGTQRL+R +GK M + L+GE L A +A GL++ + G+ Sbjct: 169 QPEIKLGLMPGAGGTQRLLRAIGKYKTMLLALTGEMLPATEAEKYGLVSRLSEEGEALEE 228 Query: 118 QVPLALRLA----------KEAMLKSYELGLEAGLNLERKSFSLLAASEDRREGIAAFKE 167 + LA ++A KEA++ + LE L LERK+F LL +ED+REGI AF Sbjct: 229 ALKLARKIALMPALAAEQIKEAVMYGEDAPLETALRLERKAFQLLFDTEDKREGIDAFLT 288 Query: 168 KRTAQFVGR 176 KR F GR Sbjct: 289 KRKPAFKGR 297