BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0012.0118.p         (229 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ydbU [I] COG1250 3-hydroxyacyl-CoA dehydrogenase Eco Escherichia...   202   6e-52
PA1628 [I] COG1250 3-hydroxyacyl-CoA dehydrogenase Pae Pseudomon...   163   4e-40
PA3590 [I] COG1250 3-hydroxyacyl-CoA dehydrogenase Pae Pseudomon...   161   1e-39
BMEII0215 [I] COG1250 3-hydroxyacyl-CoA dehydrogenase Bme Brucel...   160   3e-39
BMEII1020 [I] COG1250 3-hydroxyacyl-CoA dehydrogenase Bme Brucel...   156   3e-38

>ydbU [I] COG1250 3-hydroxyacyl-CoA dehydrogenase Eco Escherichia coli
           K12
          Length = 475

 Score =  202 bits (514), Expect = 6e-52,   Method: Compositional matrix adjust.
 Identities = 103/198 (52%), Positives = 128/198 (64%), Gaps = 14/198 (7%)

Query: 2   GMHFFNPVPLMALVEIISGLASDAAVAECVYDTALAWGKNPVHTKSTPGFIVNRVARPYY 61
           G+HFFNP P+M LVE++SGLA+ A V E + +  L+WGK PV   STPGFIVNRVARPYY
Sbjct: 140 GLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWGKQPVRCHSTPGFIVNRVARPYY 199

Query: 62  AEALRILNEQAAGPATIDAILREAGGFRMGPFELMDLIGHDVNFAVTQSVFHAYFTDPRF 121
           +EA R L EQ A P  IDA LR+  GF MGP EL DLIG DVNFAVT SVF+A++ + RF
Sbjct: 200 SEAWRALEEQVAAPEVIDAALRDGAGFPMGPLELTDLIGQDVNFAVTCSVFNAFWQERRF 259

Query: 122 TPSLIQQELVNAGFLGRKSGRGFYRYGA------------DAVAPTPATEAA--VEHASQ 167
            PSL+QQELV  G LG+KSG G Y + A            D+ +P    + +  V     
Sbjct: 260 LPSLVQQELVIGGRLGKKSGLGVYDWRAEREAVVGLEAVSDSFSPMKVEKKSDGVTEIDD 319

Query: 168 MVQLSGTGPLAEALAARL 185
           ++ +   G  A+ALA RL
Sbjct: 320 VLLIETQGETAQALAIRL 337


>PA1628 [I] COG1250 3-hydroxyacyl-CoA dehydrogenase Pae Pseudomonas
           aeruginosa
          Length = 509

 Score =  163 bits (412), Expect = 4e-40,   Method: Compositional matrix adjust.
 Identities = 83/164 (50%), Positives = 104/164 (63%), Gaps = 4/164 (2%)

Query: 2   GMHFFNPVPLMALVEIISGLASDAAVAECVYDTALAWGKNPVHTKSTPGFIVNRVARPYY 61
           G HFFNPVPLM +VE++ GLAS   V + +   A   G   V TK +PGFIVN   R Y 
Sbjct: 139 GFHFFNPVPLMRVVEVVDGLASAPEVGDALLALAARLGHRGVRTKDSPGFIVNHAGRAYG 198

Query: 62  AEALRILNEQAAGPATIDAILREAGGFRMGPFELMDLIGHDVNFAVTQSVFHAYFTDPRF 121
            EALRIL E  A  A ID +LRE  GFRMGPFEL+DL G DV+  V +S++  Y+ +PR+
Sbjct: 199 TEALRILGEGVAECAEIDRVLRECAGFRMGPFELLDLTGLDVSHPVMESIYQQYYQEPRY 258

Query: 122 TPSLIQQELVNAGFLGRKSGRGFYRY----GADAVAPTPATEAA 161
            P  + ++L+ AG LGRKSG+GFYRY      D   P P  +AA
Sbjct: 259 RPHPLTRQLLAAGRLGRKSGQGFYRYVDGQPQDKPGPQPVPQAA 302


>PA3590 [I] COG1250 3-hydroxyacyl-CoA dehydrogenase Pae Pseudomonas
           aeruginosa
          Length = 510

 Score =  161 bits (408), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 75/146 (51%), Positives = 98/146 (67%)

Query: 2   GMHFFNPVPLMALVEIISGLASDAAVAECVYDTALAWGKNPVHTKSTPGFIVNRVARPYY 61
           G+HFFNPVPLM LVE+I GLA+   +AE +      +G   V    +PGFIVN   R + 
Sbjct: 141 GLHFFNPVPLMRLVEVIEGLATRTGIAERLCALVATFGHQAVRATDSPGFIVNHAGRAFG 200

Query: 62  AEALRILNEQAAGPATIDAILREAGGFRMGPFELMDLIGHDVNFAVTQSVFHAYFTDPRF 121
            EALRIL E  A  A ID +LRE  GFRMGPFEL DL+G DV+  V +S++  Y+ +PR+
Sbjct: 201 TEALRILGEGVAPVAAIDEVLREGAGFRMGPFELFDLVGLDVSLPVMESIYRQYYEEPRY 260

Query: 122 TPSLIQQELVNAGFLGRKSGRGFYRY 147
            P  + ++++ AG LGRKSG+GFYRY
Sbjct: 261 RPHPLLRQMLAAGRLGRKSGQGFYRY 286


>BMEII0215 [I] COG1250 3-hydroxyacyl-CoA dehydrogenase Bme Brucella melitensis
          Length = 500

 Score =  160 bits (404), Expect = 3e-39,   Method: Compositional matrix adjust.
 Identities = 75/146 (51%), Positives = 97/146 (66%)

Query: 2   GMHFFNPVPLMALVEIISGLASDAAVAECVYDTALAWGKNPVHTKSTPGFIVNRVARPYY 61
           G HFFNPVPLM +VE+I G  +  AV + + + A+  G  PV+   TPGFI+N   R Y 
Sbjct: 146 GFHFFNPVPLMRVVEVIKGALTGDAVVDALKELAVRVGHRPVNATDTPGFIINHAGRAYG 205

Query: 62  AEALRILNEQAAGPATIDAILREAGGFRMGPFELMDLIGHDVNFAVTQSVFHAYFTDPRF 121
            EAL ++ E  A  ATID ILR+A GFRMGPFEL DL G +V+  V + V+H Y+ + R+
Sbjct: 206 TEALAMVKEGVADFATIDTILRDAAGFRMGPFELFDLTGLNVSHLVMEEVYHQYYEESRY 265

Query: 122 TPSLIQQELVNAGFLGRKSGRGFYRY 147
            PSLI +  + AG LGRK+GRGFY Y
Sbjct: 266 RPSLITRRRLEAGLLGRKTGRGFYDY 291


>BMEII1020 [I] COG1250 3-hydroxyacyl-CoA dehydrogenase Bme Brucella melitensis
          Length = 565

 Score =  156 bits (395), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 70/146 (47%), Positives = 97/146 (66%)

Query: 2   GMHFFNPVPLMALVEIISGLASDAAVAECVYDTALAWGKNPVHTKSTPGFIVNRVARPYY 61
           G HFFNPVPLM +VE+I GL +D AV + +   A   G + +  K  PGFI+N   R Y 
Sbjct: 180 GFHFFNPVPLMKVVEVIDGLTTDPAVGDALLVLAKRMGHHGIRAKDMPGFIINHAGRAYG 239

Query: 62  AEALRILNEQAAGPATIDAILREAGGFRMGPFELMDLIGHDVNFAVTQSVFHAYFTDPRF 121
            EAL+IL E  A    ID ILRE+ GFRMGP EL DL G DV+  V +S+++ ++ +PR+
Sbjct: 240 TEALKILGECVAPRGDIDRILRESAGFRMGPLELFDLTGLDVSHPVMESIYNQFYQEPRY 299

Query: 122 TPSLIQQELVNAGFLGRKSGRGFYRY 147
            PS + ++++  G++GRK G+GFYRY
Sbjct: 300 RPSALTRQMLEGGYVGRKVGQGFYRY 325