BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0049.p (277 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr5236 [C] COG1012 NAD-dependent aldehyde dehydrogenases Mlo Me... 333 2e-91 SMb20891 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme S... 332 7e-91 BMEI1740 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bme B... 331 1e-90 CC0822 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ccr Cau... 258 8e-69 BS_ycbD [C] COG1012 NAD-dependent aldehyde dehydrogenases Bsu Ba... 206 4e-53 >mlr5236 [C] COG1012 NAD-dependent aldehyde dehydrogenases Mlo Mesorhizobium loti Length = 479 Score = 333 bits (854), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 176/267 (65%), Positives = 206/267 (77%), Gaps = 2/267 (0%) Query: 1 MSQF-ANYINGEWLQGASVNKNINPSDLSDIVGEYAQADAAQADIAIAAAHAAFPAWSTG 59 M+QF N I+GEW+ G + + NINPSD D+VGEYA A QA AIAAA AAFP+WS Sbjct: 1 MAQFRKNLIDGEWV-GDAGSHNINPSDTGDVVGEYASAGVEQAKQAIAAAKAAFPSWSRS 59 Query: 60 NIQARSDALDKIGSEILARKEELGRLLSREEGKTLAEGIGEAGRAGNIFKFFAAEVLRIQ 119 AR L K EI+ARK+E+GR L+REEGKTLAEGIGE RA IF FFA E LR+ Sbjct: 60 GPLARHAVLKKASDEIMARKDEIGRNLAREEGKTLAEGIGETIRAAQIFDFFAGETLRLT 119 Query: 120 GQKLASVRPGMDIEITREPVGVVGIIAPWNFPMAIPAWKIAPALAYGNTVVFKPAELVPG 179 G+ + SVRPG+ +EITRE VGVVGII PWNFP+AIPAWKIAPALA+GNT+VFKPAELVP Sbjct: 120 GEMVPSVRPGVGVEITREAVGVVGIITPWNFPIAIPAWKIAPALAHGNTIVFKPAELVPE 179 Query: 180 SAWAIADIISRSGIPAGVFNLVMGRGSVVGQRFIDDRRVTALTFTGSVSTGNRVAQGCIA 239 SAW+I DI+ R+G+P GV NLVMG+GSVVGQ +D + A+TFTGSV TG RVA + Sbjct: 180 SAWSIVDILHRAGLPKGVLNLVMGKGSVVGQAMLDSPDINAITFTGSVGTGKRVAAASVE 239 Query: 240 RMAKFQLEMGGKNPLVVLNDADLSVAV 266 M KFQLEMGGKNPLVVL+DADL+VAV Sbjct: 240 HMRKFQLEMGGKNPLVVLDDADLAVAV 266 >SMb20891 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme Sinorhizobium meliloti Length = 477 Score = 332 bits (850), Expect = 7e-91, Method: Compositional matrix adjust. Identities = 177/266 (66%), Positives = 203/266 (76%), Gaps = 1/266 (0%) Query: 1 MSQFANYINGEWLQGASVNKNINPSDLSDIVGEYAQADAAQADIAIAAAHAAFPAWSTGN 60 M+ N I GEW+ G V NINPS+ D+VGEYA+A A A AIAAA AAFPAWS Sbjct: 1 MTLHQNLIAGEWVGGDGV-ANINPSNTDDVVGEYARASAEDAKAAIAAAKAAFPAWSRSG 59 Query: 61 IQARSDALDKIGSEILARKEELGRLLSREEGKTLAEGIGEAGRAGNIFKFFAAEVLRIQG 120 I R L K EILARK+ELGRLLSREEGKTLAEGIGE RAG IF+FFA E LR+ G Sbjct: 60 ILERHAILKKTADEILARKDELGRLLSREEGKTLAEGIGETVRAGQIFEFFAGETLRLAG 119 Query: 121 QKLASVRPGMDIEITREPVGVVGIIAPWNFPMAIPAWKIAPALAYGNTVVFKPAELVPGS 180 + + SVRPG+ +EITREP GVVGII PWNFP+AIPAWK+APAL YGNT+VFKPAELVPG Sbjct: 120 EVVPSVRPGIGVEITREPAGVVGIITPWNFPIAIPAWKLAPALCYGNTIVFKPAELVPGC 179 Query: 181 AWAIADIISRSGIPAGVFNLVMGRGSVVGQRFIDDRRVTALTFTGSVSTGNRVAQGCIAR 240 +WAI DI+ R+G+P GV NLVMG+GSVVGQ +D V A+TFTGS +TG RVA + Sbjct: 180 SWAIVDILHRAGLPKGVLNLVMGKGSVVGQAMLDSPDVQAITFTGSTATGKRVAVASVEH 239 Query: 241 MAKFQLEMGGKNPLVVLNDADLSVAV 266 K+QLEMGGKNP VVL+DADLSVAV Sbjct: 240 NRKYQLEMGGKNPFVVLDDADLSVAV 265 >BMEI1740 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bme Brucella melitensis Length = 477 Score = 331 bits (849), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 176/266 (66%), Positives = 199/266 (74%), Gaps = 1/266 (0%) Query: 1 MSQFANYINGEWLQGASVNKNINPSDLSDIVGEYAQADAAQADIAIAAAHAAFPAWSTGN 60 M+ N I GEW+ G + NINPSD +D+VG YA+A A AIAAA AAFPAWS Sbjct: 1 MTFHQNLIAGEWVGGDDI-ANINPSDTNDVVGTYARATAEDTKAAIAAAKAAFPAWSRSG 59 Query: 61 IQARSDALDKIGSEILARKEELGRLLSREEGKTLAEGIGEAGRAGNIFKFFAAEVLRIQG 120 I R L K EILARKEELGRLLSREEGKTL EGIGE RA IF FFA E LR+ G Sbjct: 60 ILERHAILRKTADEILARKEELGRLLSREEGKTLVEGIGETIRASQIFDFFAGECLRLAG 119 Query: 121 QKLASVRPGMDIEITREPVGVVGIIAPWNFPMAIPAWKIAPALAYGNTVVFKPAELVPGS 180 + L S RPG+ +E+TREPVGVVGII PWNFP+AIPAWKIAPAL YGNT+VFKPAELVPG Sbjct: 120 EVLPSARPGIGVEVTREPVGVVGIITPWNFPIAIPAWKIAPALCYGNTIVFKPAELVPGC 179 Query: 181 AWAIADIISRSGIPAGVFNLVMGRGSVVGQRFIDDRRVTALTFTGSVSTGNRVAQGCIAR 240 +WAIADI+ R+G+P GV NLVMG+GSVVGQ +D V A TFTGS TG RVA I Sbjct: 180 SWAIADILHRAGLPKGVLNLVMGKGSVVGQTILDSADVNAATFTGSTGTGKRVAAASIEH 239 Query: 241 MAKFQLEMGGKNPLVVLNDADLSVAV 266 +FQLEMGGKNP+VVL+DADL+VAV Sbjct: 240 NRRFQLEMGGKNPVVVLDDADLNVAV 265 >CC0822 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ccr Caulobacter vibrioides Length = 478 Score = 258 bits (660), Expect = 8e-69, Method: Compositional matrix adjust. Identities = 143/261 (54%), Positives = 186/261 (71%), Gaps = 1/261 (0%) Query: 6 NYINGEWLQGASVNKNINPSDLSDIVGEYAQADAAQADIAIAAAHAAFPAWSTGNIQARS 65 +YI GE + + +++NPS+ +D+V + A+ D A+ AA AFPAW+ + + RS Sbjct: 7 HYIGGERVAADAPAESLNPSNTNDVVAKVPMGGQAEVDAAVDAARKAFPAWADASPEVRS 66 Query: 66 DALDKIGSEILARKEELGRLLSREEGKTLAEGIGEAGRAGNIFKFFAAEVLRIQGQKLAS 125 D LDK+GS I+AR ++GRLL+REEGKTLAEGIGE RAG IFK+FA E LR GQ L S Sbjct: 67 DLLDKVGSTIIARSADIGRLLAREEGKTLAEGIGETVRAGRIFKYFAGEALRRHGQNLES 126 Query: 126 VRPGMDIEITREPVGVVGIIAPWNFPMAIPAWKIAPALAYGNTVVFKPAELVPGSAWAIA 185 RPG++I+ R+ VGV G+I PWNFP+AIPAWK APALA+GNTVV KPA P +A +A Sbjct: 127 TRPGVEIQTYRQAVGVYGLITPWNFPIAIPAWKAAPALAFGNTVVIKPAGPTPATANVLA 186 Query: 186 DIISRSGIPAGVFNLVMGRGSVVGQRFIDDRRVTALTFTGSVSTGNRVAQGCIARMAKFQ 245 DI++ G PAGVFN++ GRGS +G I + V ++FTGS G +VA +AR A+ Q Sbjct: 187 DIMAECGAPAGVFNMLFGRGS-MGDALIKHKDVDGVSFTGSQGVGAQVAAAAVARQARVQ 245 Query: 246 LEMGGKNPLVVLNDADLSVAV 266 LEMGGKNPL+VL+DADL AV Sbjct: 246 LEMGGKNPLIVLDDADLERAV 266 >BS_ycbD [C] COG1012 NAD-dependent aldehyde dehydrogenases Bsu Bacillus subtilis Length = 488 Score = 206 bits (525), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 114/255 (44%), Positives = 149/255 (58%), Gaps = 2/255 (0%) Query: 4 FANYINGEWL--QGASVNKNINPSDLSDIVGEYAQADAAQADIAIAAAHAAFPAWSTGNI 61 + N+INGEW+ Q + K NP+D++DIVG + A + A+ AA+ A AW Sbjct: 10 YLNFINGEWVKSQSGDMVKVENPADVNDIVGYVQNSTAEDVERAVTAANEAKTAWRKLTG 69 Query: 62 QARSDALDKIGSEILARKEELGRLLSREEGKTLAEGIGEAGRAGNIFKFFAAEVLRIQGQ 121 R L K + R EE+ +RE GKTL E GE R I +++A E +R G Sbjct: 70 AERGQYLYKTADIMEQRLEEIAACATREMGKTLPEAKGETARGIAILRYYAGEGMRKTGD 129 Query: 122 KLASVRPGMDIEITREPVGVVGIIAPWNFPMAIPAWKIAPALAYGNTVVFKPAELVPGSA 181 + S + TR P+GVVG+I+PWNFP+AIP WK+APAL YGNTVV KPA + Sbjct: 130 VIPSTDKDALMFTTRVPLGVVGVISPWNFPVAIPIWKMAPALVYGNTVVIKPATETAVTC 189 Query: 182 WAIADIISRSGIPAGVFNLVMGRGSVVGQRFIDDRRVTALTFTGSVSTGNRVAQGCIARM 241 I +G+PAGV NLV G GSVVGQ + V A+TFTGS G + Q +AR Sbjct: 190 AKIIACFEEAGLPAGVINLVTGPGSVVGQGLAEHDGVNAVTFTGSNQVGKIIGQAALARG 249 Query: 242 AKFQLEMGGKNPLVV 256 AK+QLEMGGKNP++V Sbjct: 250 AKYQLEMGGKNPVIV 264