BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0027.p (438 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1010 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase... 505 e-143 PA3139 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase ... 489 e-138 ZtyrB [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase E... 420 e-117 ECs5036 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase... 420 e-117 tyrB [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase Ec... 419 e-117 >RSc1010 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase Rso Ralstonia solanacearum Length = 398 Score = 505 bits (1301), Expect = e-143, Method: Compositional matrix adjust. Identities = 250/378 (66%), Positives = 297/378 (78%), Gaps = 1/378 (0%) Query: 10 SLFTAIEMAPRDPILGITDAYNADKNPGKTNLGVGVYYDDNGKVPLLECVKKAEAELAAK 69 SLF+A+E+APRDPILG+ +A+NAD K NLGVGVY+ D GK+P+L V++AE A Sbjct: 2 SLFSAVELAPRDPILGLNEAFNADARSTKVNLGVGVYFTDEGKIPVLRAVQEAEKARLAM 61 Query: 70 LAPRTYLPIDGLATYDKAVQELVFGADSAVVQEKRAITVQALGGTGALKLGADFIKHFSP 129 APR YLPI+G+A YD+AVQ+L+FGADS ++ E R +T QALGGTGALK+GADF+K P Sbjct: 62 AAPRGYLPIEGIAAYDQAVQKLLFGADSPLLAEGRVVTAQALGGTGALKIGADFLKRLYP 121 Query: 130 ASTQIWISDPSWENHRALFEMAGFTVNNYPYYDAATRGVNFAGMLDALKTMAAGSVVLLH 189 ++ ISDPSWENHRALFE AGF V NYPYYDA T G+NFA ML+AL A ++V+LH Sbjct: 122 -DAKVAISDPSWENHRALFEAAGFPVVNYPYYDAPTHGLNFAAMLEALNGYAPNTIVVLH 180 Query: 190 ACCHNPTGADLTADQWTQVIEVVTSRGLIPFLDMAYQGFGDGIEEDGKVVRRFAEAGGPL 249 ACCHNPTG DLT +QW QV+EV+ ++ LIPFLDMAYQGF DGI +DG V FAE+G Sbjct: 181 ACCHNPTGVDLTTEQWKQVVEVIKAKQLIPFLDMAYQGFADGIAQDGLAVSLFAESGLQF 240 Query: 250 FVSNSFSKSFSLYGERVGALSIVASTNEEAARVLSQLKRVVRTNYSNPPIHGGQVVATAL 309 FVS+SFSKSFSLYGERVGALSIV ++ +EAARV+SQ+KRV+RTNYSNPP HGG VVA+ L Sbjct: 241 FVSSSFSKSFSLYGERVGALSIVTTSKDEAARVMSQVKRVIRTNYSNPPTHGGTVVASVL 300 Query: 310 ASPELRALWESELAEMRVRIREMRQLLVAKLKEKAPAHDFDFVIKQRGMFSYSGLTKAQV 369 SPELRA+WE EL EMR RI+ MR LV KL K DF FV QRGMFSYSGL+ AQV Sbjct: 301 TSPELRAMWEQELGEMRDRIKSMRHALVDKLAAKGVKTDFSFVKAQRGMFSYSGLSAAQV 360 Query: 370 ERLRNEFSIYAVDTGRIC 387 +RLRNE IYAV TGRIC Sbjct: 361 DRLRNEHGIYAVSTGRIC 378 >PA3139 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase Pae Pseudomonas aeruginosa Length = 398 Score = 489 bits (1260), Expect = e-138, Method: Compositional matrix adjust. Identities = 242/378 (64%), Positives = 294/378 (77%), Gaps = 1/378 (0%) Query: 10 SLFTAIEMAPRDPILGITDAYNADKNPGKTNLGVGVYYDDNGKVPLLECVKKAEAELAAK 69 SLF+A+EMAPRDPILG+ +A+NAD PGK NLGVGVYY++ G++PLL V+ AE Sbjct: 2 SLFSAVEMAPRDPILGLNEAFNADTRPGKINLGVGVYYNEEGRIPLLRAVQAAEKARIEA 61 Query: 70 LAPRTYLPIDGLATYDKAVQELVFGADSAVVQEKRAITVQALGGTGALKLGADFIKHFSP 129 APR YLPI+G+A YD+ VQ+L+FG +S ++ R +T QA+GGTGALKLGADF+K P Sbjct: 62 HAPRGYLPIEGIAAYDQGVQKLLFGNESELLAAGRVVTTQAVGGTGALKLGADFLKRLLP 121 Query: 130 ASTQIWISDPSWENHRALFEMAGFTVNNYPYYDAATRGVNFAGMLDALKTMAAGSVVLLH 189 +T + ISDPSWENHRALFE AGF V NY YYDAA+ GVN AG+L+ L + A S+V+LH Sbjct: 122 DAT-VAISDPSWENHRALFEAAGFPVQNYRYYDAASNGVNRAGLLEDLNALPARSIVVLH 180 Query: 190 ACCHNPTGADLTADQWTQVIEVVTSRGLIPFLDMAYQGFGDGIEEDGKVVRRFAEAGGPL 249 ACCHNPTG DL D W QV++V+ ++G +PFLD+AYQGFG+GIEED VR FA++G Sbjct: 181 ACCHNPTGVDLELDDWKQVLDVLKAKGHVPFLDIAYQGFGNGIEEDAAAVRLFAQSGLSF 240 Query: 250 FVSNSFSKSFSLYGERVGALSIVASTNEEAARVLSQLKRVVRTNYSNPPIHGGQVVATAL 309 FVS+SFSKSFSLYGERVGALSIV + +E+ARVLSQ+KRV+RTNYSNPP HG VV++ L Sbjct: 241 FVSSSFSKSFSLYGERVGALSIVTESRDESARVLSQVKRVIRTNYSNPPTHGASVVSSVL 300 Query: 310 ASPELRALWESELAEMRVRIREMRQLLVAKLKEKAPAHDFDFVIKQRGMFSYSGLTKAQV 369 SPELRALWE EL EMR RIR+MR +V +L DF FV +QRGMFSYSGLT QV Sbjct: 301 NSPELRALWEQELGEMRDRIRDMRLAMVEQLAAHGAKRDFSFVGRQRGMFSYSGLTADQV 360 Query: 370 ERLRNEFSIYAVDTGRIC 387 ERL+ EF IYAV TGRIC Sbjct: 361 ERLKTEFGIYAVSTGRIC 378 >ZtyrB [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase EcZ Escherichia coli O157:H7 EDL933 Length = 397 Score = 420 bits (1080), Expect = e-117, Method: Compositional matrix adjust. Identities = 202/378 (53%), Positives = 262/378 (69%), Gaps = 2/378 (0%) Query: 11 LFTAIEMAPRDPILGITDAYNADKNPGKTNLGVGVYYDDNGKVPLLECVKKAEAEL-AAK 69 +F ++ DPIL + + + D K NL +G+YY+++G +P L+ V +AEA L A Sbjct: 1 MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIPQLKAVAEAEARLNAVP 60 Query: 70 LAPRTYLPIDGLATYDKAVQELVFGADSAVVQEKRAITVQALGGTGALKLGADFIKHFSP 129 YLP++GL +Y A+ L+FGAD V+Q++R T+Q LGG+GALK+GADF+K + P Sbjct: 61 HGASLYLPMEGLNSYRHAIAPLLFGADHPVLQQQRVATIQTLGGSGALKVGADFLKRYFP 120 Query: 130 ASTQIWISDPSWENHRALFEMAGFTVNNYPYYDAATRGVNFAGMLDALKTMAAGSVVLLH 189 S +W+SDP+WENH A+F AGF V+ YP+YD AT GV F +L LKT+ A S+VLLH Sbjct: 121 ESG-VWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRFNDLLAMLKTLPARSIVLLH 179 Query: 190 ACCHNPTGADLTADQWTQVIEVVTSRGLIPFLDMAYQGFGDGIEEDGKVVRRFAEAGGPL 249 CCHNPTGADLT DQW VIE++ +R LIPFLD+AYQGFG G+EED +R A AG P Sbjct: 180 PCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGFGAGMEEDAYAIRAIASAGLPA 239 Query: 250 FVSNSFSKSFSLYGERVGALSIVASTNEEAARVLSQLKRVVRTNYSNPPIHGGQVVATAL 309 VSNSFSK FSLYGERVG LS++ E A RVL QLK VR NYS+PP G QVVA L Sbjct: 240 LVSNSFSKIFSLYGERVGGLSVLCEDAEAAGRVLGQLKATVRRNYSSPPNFGAQVVAAVL 299 Query: 310 ASPELRALWESELAEMRVRIREMRQLLVAKLKEKAPAHDFDFVIKQRGMFSYSGLTKAQV 369 L+A W +E+ EMR RI MRQ LV L + P +FD+++ QRGMFSY+GL+ AQV Sbjct: 300 NDEALKASWLAEVEEMRTRILAMRQELVKVLSTEMPERNFDYLLNQRGMFSYTGLSAAQV 359 Query: 370 ERLRNEFSIYAVDTGRIC 387 +RLR EF +Y + +GR+C Sbjct: 360 DRLREEFGVYLIASGRMC 377 >ECs5036 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase Ecs Escherichia coli O157:H7 Length = 397 Score = 420 bits (1080), Expect = e-117, Method: Compositional matrix adjust. Identities = 202/378 (53%), Positives = 262/378 (69%), Gaps = 2/378 (0%) Query: 11 LFTAIEMAPRDPILGITDAYNADKNPGKTNLGVGVYYDDNGKVPLLECVKKAEAEL-AAK 69 +F ++ DPIL + + + D K NL +G+YY+++G +P L+ V +AEA L A Sbjct: 1 MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIPQLKAVAEAEARLNAVP 60 Query: 70 LAPRTYLPIDGLATYDKAVQELVFGADSAVVQEKRAITVQALGGTGALKLGADFIKHFSP 129 YLP++GL +Y A+ L+FGAD V+Q++R T+Q LGG+GALK+GADF+K + P Sbjct: 61 HGASLYLPMEGLNSYRHAIAPLLFGADHPVLQQQRVATIQTLGGSGALKVGADFLKRYFP 120 Query: 130 ASTQIWISDPSWENHRALFEMAGFTVNNYPYYDAATRGVNFAGMLDALKTMAAGSVVLLH 189 S +W+SDP+WENH A+F AGF V+ YP+YD AT GV F +L LKT+ A S+VLLH Sbjct: 121 ESG-VWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRFNDLLAMLKTLPARSIVLLH 179 Query: 190 ACCHNPTGADLTADQWTQVIEVVTSRGLIPFLDMAYQGFGDGIEEDGKVVRRFAEAGGPL 249 CCHNPTGADLT DQW VIE++ +R LIPFLD+AYQGFG G+EED +R A AG P Sbjct: 180 PCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGFGAGMEEDAYAIRAIASAGLPA 239 Query: 250 FVSNSFSKSFSLYGERVGALSIVASTNEEAARVLSQLKRVVRTNYSNPPIHGGQVVATAL 309 VSNSFSK FSLYGERVG LS++ E A RVL QLK VR NYS+PP G QVVA L Sbjct: 240 LVSNSFSKIFSLYGERVGGLSVLCEDAEAAGRVLGQLKATVRRNYSSPPNFGAQVVAAVL 299 Query: 310 ASPELRALWESELAEMRVRIREMRQLLVAKLKEKAPAHDFDFVIKQRGMFSYSGLTKAQV 369 L+A W +E+ EMR RI MRQ LV L + P +FD+++ QRGMFSY+GL+ AQV Sbjct: 300 NDEALKASWLAEVEEMRTRILAMRQELVKVLSTEMPERNFDYLLNQRGMFSYTGLSAAQV 359 Query: 370 ERLRNEFSIYAVDTGRIC 387 +RLR EF +Y + +GR+C Sbjct: 360 DRLREEFGVYLIASGRMC 377 >tyrB [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase Eco Escherichia coli K12 Length = 397 Score = 419 bits (1077), Expect = e-117, Method: Compositional matrix adjust. Identities = 201/378 (53%), Positives = 262/378 (69%), Gaps = 2/378 (0%) Query: 11 LFTAIEMAPRDPILGITDAYNADKNPGKTNLGVGVYYDDNGKVPLLECVKKAEAELAAK- 69 +F ++ DPIL + + + D K NL +G+YY+++G +P L+ V +AEA L A+ Sbjct: 1 MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIPQLQAVAEAEARLNAQP 60 Query: 70 LAPRTYLPIDGLATYDKAVQELVFGADSAVVQEKRAITVQALGGTGALKLGADFIKHFSP 129 YLP++GL Y A+ L+FGAD V++++R T+Q LGG+GALK+GADF+K + P Sbjct: 61 HGASLYLPMEGLNCYRHAIAPLLFGADHPVLKQQRVATIQTLGGSGALKVGADFLKRYFP 120 Query: 130 ASTQIWISDPSWENHRALFEMAGFTVNNYPYYDAATRGVNFAGMLDALKTMAAGSVVLLH 189 S +W+SDP+WENH A+F AGF V+ YP+YD AT GV F +L LKT+ A S+VLLH Sbjct: 121 ESG-VWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRFNDLLATLKTLPARSIVLLH 179 Query: 190 ACCHNPTGADLTADQWTQVIEVVTSRGLIPFLDMAYQGFGDGIEEDGKVVRRFAEAGGPL 249 CCHNPTGADLT DQW VIE++ +R LIPFLD+AYQGFG G+EED +R A AG P Sbjct: 180 PCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGFGAGMEEDAYAIRAIASAGLPA 239 Query: 250 FVSNSFSKSFSLYGERVGALSIVASTNEEAARVLSQLKRVVRTNYSNPPIHGGQVVATAL 309 VSNSFSK FSLYGERVG LS++ E A RVL QLK VR NYS+PP G QVVA L Sbjct: 240 LVSNSFSKIFSLYGERVGGLSVMCEDAEAAGRVLGQLKATVRRNYSSPPNFGAQVVAAVL 299 Query: 310 ASPELRALWESELAEMRVRIREMRQLLVAKLKEKAPAHDFDFVIKQRGMFSYSGLTKAQV 369 L+A W +E+ EMR RI MRQ LV L + P +FD+++ QRGMFSY+GL+ AQV Sbjct: 300 NDEALKASWLAEVEEMRTRILAMRQELVKVLSTEMPERNFDYLLNQRGMFSYTGLSAAQV 359 Query: 370 ERLRNEFSIYAVDTGRIC 387 +RLR EF +Y + +GR+C Sbjct: 360 DRLREEFGVYLIASGRMC 377