BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0077.p (567 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1075 [U] COG2831 Hemolysin activation/secretion protein Rso R... 602 e-172 XF2550 [U] COG2831 Hemolysin activation/secretion protein Xfa Xy... 531 e-150 YPO0598 [U] COG2831 Hemolysin activation/secretion protein Ype Y... 437 e-122 YPO2491 [U] COG2831 Hemolysin activation/secretion protein Ype Y... 436 e-122 NMB1762 [U] COG2831 Hemolysin activation/secretion protein Nme N... 420 e-117 >RSp1075 [U] COG2831 Hemolysin activation/secretion protein Rso Ralstonia solanacearum Length = 578 Score = 602 bits (1551), Expect = e-172, Method: Compositional matrix adjust. Identities = 306/559 (54%), Positives = 379/559 (67%), Gaps = 5/559 (0%) Query: 13 AMLLASGSVQAQTTGTDIAANQEQLQRERERLLRQQQEQSPDVRLPAPKEVDVSTIFPVQ 72 A LL AQ + A + Q+ERER LRQ+QE PDVRL + + P Sbjct: 21 ACLLPMSMALAQIAPAEDATQELLRQQERERALRQRQESKPDVRLERGVAAETGRL-PAD 79 Query: 73 ESPCFPISRISLIGEAAERFQFALSSVT-GQGGALGSCLGTEGVNIVIAHMQNALILRGY 131 ESPCF I RI+L G+AAERFQ+AL + A G CLGT G+N+V+ +QNA++ RGY Sbjct: 80 ESPCFRIDRITLTGDAAERFQWALPAADPSDDPATGRCLGTAGINLVMKRVQNAIVARGY 139 Query: 132 TTSQIRAATQDLKTGELVLTILPGHVRHIRFAPDASPRGTAWNALPINAGDILNLRDIEQ 191 T+++ AA QDLK G L LT++PG +R IRF+ D+SPR T WNALP GDILNLRDIEQ Sbjct: 140 VTTRVLAAPQDLKQGTLALTLVPGRIRAIRFSDDSSPRATRWNALPAAPGDILNLRDIEQ 199 Query: 192 GLENFKRVSTAQADIEVAPTEA-AERPGDSDLVIRYQQSFPFRFNVALDDGGSKATGKYQ 250 GLENFKRV TA ADI++AP + PG+SDLVI ++Q PFR NVA DD GSK TGKYQ Sbjct: 200 GLENFKRVPTADADIQIAPADGPGATPGESDLVIAWKQGLPFRLNVAADDSGSKYTGKYQ 259 Query: 251 AGATLSYDNWWTLNDLFYASWNRSLG--HYGDHGVNSYTVHYSVPAGYWMLGGTLSGSRY 308 T+SYD+WWTLNDLFYAS+N LG + G G YTVHY VP YW+LG T S Y Sbjct: 260 GSVTVSYDHWWTLNDLFYASFNHDLGGGYSGSKGTRGYTVHYEVPYDYWLLGFTTSSYDY 319 Query: 309 HQQVAGANNSIIYSGQSENAELKLSRLIYRDAVRKTTLSLKGLLRNSRNFIDDTEVGPQR 368 +Q V GAN + IYSG SEN+E++LSRL YRDAVRKT+ ++G +R+S NFIDDTEV QR Sbjct: 320 YQSVVGANQTYIYSGTSENSEVRLSRLFYRDAVRKTSAYVRGWVRSSANFIDDTEVEVQR 379 Query: 369 HRTSAWEAGVNHREFIGDATVDANLVYRRALDKQGREPESTADLPQLATRYGLFVADATI 428 R + WE G+NHREFIG AT+DAN+ YR+ P + R L ADA + Sbjct: 380 RRMAGWEIGLNHREFIGAATLDANVAYRKGTGMLSSLPAPEESFDEGTARPSLITADAQL 439 Query: 429 NAPFQIAGQRLRYNGSVRTQWNRGALPSQDQFAIGGRYTVRGFDGELILQAERGWLVRNE 488 PF +A QRLRY + R QWNR L QD+F+IGGRYTVRGFDGE L +RGWLVRN+ Sbjct: 440 TVPFAVASQRLRYTTAWRGQWNRTPLVPQDRFSIGGRYTVRGFDGENTLIGDRGWLVRND 499 Query: 489 LALALGQGNQELYAGIDAGQVSGPSAQYLLGDRLAGAVIGLRGAFWTVSYDAFIARPLNK 548 L LG QELY G+D G+V G SA+ L+G LAGAV+GLRG + + +D FI PL+K Sbjct: 500 LGWTLGNSGQELYVGVDYGEVGGQSARVLIGQHLAGAVLGLRGGYKGLFWDVFIGTPLSK 559 Query: 549 PDGFKTADVTGGFSVNLAF 567 P+GF+TA T GF+V+ ++ Sbjct: 560 PEGFRTAHTTAGFNVSWSY 578 >XF2550 [U] COG2831 Hemolysin activation/secretion protein Xfa Xylella fastidiosa 9a5c Length = 597 Score = 531 bits (1367), Expect = e-150, Method: Compositional matrix adjust. Identities = 283/565 (50%), Positives = 366/565 (64%), Gaps = 13/565 (2%) Query: 8 LLSSLAMLLASGSVQAQTTGTDIAANQEQL-QRERERLLRQQQEQSPDVRLPAPKEV--D 64 LL +A LL S AQ D QE L Q+ERER LR+Q E+ D RL +EV Sbjct: 41 LLPLIAALLQQQSAYAQVAPPD----QELLRQQERERALREQLERDTDARL---QEVPGK 93 Query: 65 VSTIFPVQESPCFPISRISLIGEAAERFQFALSSVTG-QGGALGSCLGTEGVNIVIAHMQ 123 ++ P E+PCFPI +I L G+ A RFQ+AL++ A+G CLGT G+NIVI+ +Q Sbjct: 94 TPSLLPRDETPCFPIQKIFLEGDKAARFQWALTAANPPHDPAIGRCLGTAGINIVISRVQ 153 Query: 124 NALILRGYTTSQIRAATQDLKTGELVLTILPGHVRHIRFAPDASPRGTAWNALPINAGDI 183 NA+I RGY T+++ AA QDLK+GEL LT++PG + HIRFAP P T WNA+P + GD+ Sbjct: 154 NAIISRGYVTTRVLAAPQDLKSGELHLTLIPGRLAHIRFAPGTKPDATFWNAIPAHPGDL 213 Query: 184 LNLRDIEQGLENFKRVSTAQADIEVAPTEA-AERPGDSDLVIRYQQSFPFRFNVALDDGG 242 LNLRDIEQGLENFKRV T +ADI++ PTE +PG SDL+I + Q P RFN + DD G Sbjct: 214 LNLRDIEQGLENFKRVPTVEADIQIVPTEGDNSQPGQSDLLISWTQGRPVRFNASFDDSG 273 Query: 243 SKATGKYQAGATLSYDNWWTLNDLFYASWNRSLGHYGDHGVNSYTVHYSVPAGYWMLGGT 302 SK+TGK QAGATLS D+ T NDLFY S NRS + G T+HYS+P G W++ T Sbjct: 274 SKSTGKTQAGATLSLDHALTQNDLFYISLNRSAFNGSKRGTRGITLHYSMPLGNWLIAAT 333 Query: 303 LSGSRYHQQVAGANNSIIYSGQSENAELKLSRLIYRDAVRKTTLSLKGLLRNSRNFIDDT 362 SG YHQ +AG+ + IYSG+S N+ELKLSR + R A K+ + L+G R+S+NFIDDT Sbjct: 334 HSGYNYHQSIAGSQQTYIYSGESHNSELKLSRRLIRTARSKSGIYLRGWTRDSKNFIDDT 393 Query: 363 EVGPQRHRTSAWEAGVNHREFIGDATVDANLVYRRALDKQGREPESTADLPQLATRYGLF 422 EV QR R + WE G+ +R +I AT+D L +RR G P + +R ++ Sbjct: 394 EVLVQRRRMAGWEMGLTYRRYISTATLDTTLGFRRGTGAFGALPAPEELFDEGTSRPKIY 453 Query: 423 VADATINAPFQIAGQRLRYNGSVRTQWNRGALPSQDQFAIGGRYTVRGFDGELILQAERG 482 ADA N PFQ+ Q LRY GS R QWNR L +QD+F+IGGRYTVRGFDGE L ERG Sbjct: 454 FADAQFNLPFQLGRQSLRYTGSWRAQWNRTPLITQDRFSIGGRYTVRGFDGETTLIGERG 513 Query: 483 WLVRNELALALGQGNQELYAGIDAGQVSGPSAQYLLGDRLAGAVIGLRGAFWTVSYDAFI 542 WL+RN+L L+LG G+QE Y +D + G SA G+ LAG +GLRG ++ +D F+ Sbjct: 514 WLLRNDLGLSLG-GDQEAYLALDYAHIGGASAYLQQGNHLAGTALGLRGGHRSLFWDVFV 572 Query: 543 ARPLNKPDGFKTADVTGGFSVNLAF 567 P+N+P F A GFS+N +F Sbjct: 573 GAPINRPRTFSNAYTVTGFSLNWSF 597 >YPO0598 [U] COG2831 Hemolysin activation/secretion protein Ype Yersinia pestis Length = 562 Score = 437 bits (1124), Expect = e-122, Method: Compositional matrix adjust. Identities = 235/556 (42%), Positives = 337/556 (60%), Gaps = 8/556 (1%) Query: 14 MLLASGSVQAQTTGTDIAANQEQL-QRERERLLRQQ-QEQSPDVRLPAPKEVDVSTIFPV 71 +LL ++ + G ++A Q+ + Q+ER+R L ++ +PDVRL AP IFP+ Sbjct: 13 VLLKIVAIPDASYGAELAPVQQSIHQQERQRALEERLAPPTPDVRLSAPSAFFSRIIFPL 72 Query: 72 QESPCFPISRISLIGEAAERFQFALSSVTGQGGALGSCLGTEGVNIVIAHMQNALILRGY 131 E+PCF I+RI + G L + Q A G CLG +G+N++++ MQN L+ GY Sbjct: 73 -ETPCFVINRIKISGAEPLPRWLPLQRIADQ--AQGQCLGAKGINLLMSQMQNRLVDHGY 129 Query: 132 TTSQIRAATQDLKTGELVLTILPGHVRHIRFAPDASPRGTAWNALPINAGDILNLRDIEQ 191 T+++ A QDL +G L L ++PG +R + PD++ T ++A P AG +L+LRDIEQ Sbjct: 130 VTTRVLAPQQDLNSGTLALNVVPGKIRGVELTPDSNRYVTLFSAFPARAGTLLDLRDIEQ 189 Query: 192 GLENFKRVSTAQADIEVAPTEAAERPGDSDLVIRYQQSFPFRFNVALDDGGSKATGKYQA 251 GLEN +RV T QA++ + P A PG++D+++ +QQ +R +LDD G+++TG+YQ Sbjct: 190 GLENLQRVPTVQANMVLIPGSA---PGETDIILNWQQRKMWRLAASLDDSGTRSTGRYQG 246 Query: 252 GATLSYDNWWTLNDLFYASWNRSLGHYGDHGVNSYTVHYSVPAGYWMLGGTLSGSRYHQQ 311 GATL DN +L+DLFY S +L GD G N+ T HYS+P GYW G T S Y+Q Sbjct: 247 GATLFLDNPLSLSDLFYVSAGGALQRRGDKGTNNLTGHYSLPFGYWTAGMTASRYDYYQA 306 Query: 312 VAGANNSIIYSGQSENAELKLSRLIYRDAVRKTTLSLKGLLRNSRNFIDDTEVGPQRHRT 371 VAG N I Y G+SEN +LSRL++R+A +KTT + L R+S+N+I+DTEV QR RT Sbjct: 307 VAGLNGDINYRGESENVAFQLSRLLHRNASQKTTFTYDVLTRSSKNYINDTEVEVQRRRT 366 Query: 372 SAWEAGVNHREFIGDATVDANLVYRRALDKQGREPESTADLPQLATRYGLFVADATINAP 431 SAW G+ HR FI A +DA + Y+R G P + + +A ++ P Sbjct: 367 SAWRIGLQHRHFISQAILDAGISYQRGTRWFGAIPAQEEYFGEATALSKILRLNAQLDIP 426 Query: 432 FQIAGQRLRYNGSVRTQWNRGALPSQDQFAIGGRYTVRGFDGELILQAERGWLVRNELAL 491 F + Q L YN + Q L QDQF+IGGR++VRGF+GE L A+RGW VRN++ Sbjct: 427 FVVMAQNLHYNLQYQRQSTNTPLTPQDQFSIGGRWSVRGFNGERTLIADRGWWVRNDIGW 486 Query: 492 ALGQGNQELYAGIDAGQVSGPSAQYLLGDRLAGAVIGLRGAFWTVSYDAFIARPLNKPDG 551 L ELY G+D G+V G S YLLG LAG+ +G+RG YD F +PL+KP+G Sbjct: 487 YLPLPGHELYVGVDYGEVGGRSGAYLLGRHLAGSAVGVRGNVLNTRYDLFAGKPLSKPNG 546 Query: 552 FKTADVTGGFSVNLAF 567 FKT + GF++N + Sbjct: 547 FKTDSLAVGFNLNWLY 562 >YPO2491 [U] COG2831 Hemolysin activation/secretion protein Ype Yersinia pestis Length = 562 Score = 436 bits (1121), Expect = e-122, Method: Compositional matrix adjust. Identities = 229/531 (43%), Positives = 326/531 (61%), Gaps = 7/531 (1%) Query: 38 QRERERLLRQQ-QEQSPDVRLPAPKEVDVSTIFPVQESPCFPISRISLIGEAAERFQFAL 96 Q+ER+R L ++ +PDVRL AP IFPV E PCF I R++L G L Sbjct: 38 QQERQRALEERLAPPTPDVRLSAPSASSDRLIFPV-EKPCFVIDRVTLSGTEPLPRWLPL 96 Query: 97 SSVTGQGGALGSCLGTEGVNIVIAHMQNALILRGYTTSQIRAATQDLKTGELVLTILPGH 156 + Q ALG CLG +G+N +++ +QN L+ GY T+++ A QDL +G L L ++PG Sbjct: 97 QRIANQ--ALGQCLGGQGINQLMSQLQNRLVGHGYVTTRVLAPQQDLNSGTLALQVVPGK 154 Query: 157 VRHIRFAPDASPRGTAWNALPINAGDILNLRDIEQGLENFKRVSTAQADIEVAPTEAAER 216 + + P++ T ++A P G +L+LRDIEQGLEN +R+ T QA +E+ P A Sbjct: 155 IHRVALTPESDRHVTLFSAFPARPGHLLDLRDIEQGLENLQRIPTVQASMELIPGSA--- 211 Query: 217 PGDSDLVIRYQQSFPFRFNVALDDGGSKATGKYQAGATLSYDNWWTLNDLFYASWNRSLG 276 PG++D+ + ++QS +R +LDD G+++TG+YQ GATL DN ++L+D FY S S+ Sbjct: 212 PGETDIALSWKQSKMWRLAASLDDSGTRSTGRYQGGATLFLDNPFSLSDQFYVSAGGSIK 271 Query: 277 HYGDHGVNSYTVHYSVPAGYWMLGGTLSGSRYHQQVAGANNSIIYSGQSENAELKLSRLI 336 + GD G N+ T HYS+P GYW G T S YHQ VAG N+ Y G+SEN L+LSRL+ Sbjct: 272 NRGDKGTNNLTGHYSLPFGYWTAGITASSYDYHQTVAGLNSDYNYRGESENVSLQLSRLL 331 Query: 337 YRDAVRKTTLSLKGLLRNSRNFIDDTEVGPQRHRTSAWEAGVNHREFIGDATVDANLVYR 396 +R+A +KTTL+ L R+S+N+I+DTEV QR RTSAW G+ HR FI AT+DA + Y+ Sbjct: 332 HRNASQKTTLTYDVLTRSSKNYINDTEVEVQRRRTSAWRIGLQHRHFISQATLDAGVSYQ 391 Query: 397 RALDKQGREPESTADLPQLATRYGLFVADATINAPFQIAGQRLRYNGSVRTQWNRGALPS 456 R G P + + +A ++ PF + Q YN + Q + L Sbjct: 392 RGTRWFGAVPAQEEYFDEGTALSKILQLNAQLDIPFSVMAQNFHYNVQYQRQSSSTPLTP 451 Query: 457 QDQFAIGGRYTVRGFDGELILQAERGWLVRNELALALGQGNQELYAGIDAGQVSGPSAQY 516 QDQF+IGGR++VRGF+GE L A+RGW VRN+L QE+Y G+D G+V G + Y Sbjct: 452 QDQFSIGGRWSVRGFNGERTLSADRGWTVRNDLGWYTPIQGQEIYVGLDYGEVGGRGSAY 511 Query: 517 LLGDRLAGAVIGLRGAFWTVSYDAFIARPLNKPDGFKTADVTGGFSVNLAF 567 LLG+ LAGA +G+RG YD F +PL++PDGF++ VT GF++N + Sbjct: 512 LLGNHLAGAAVGIRGNVLNTRYDLFAGKPLSEPDGFQSDAVTVGFNLNWQY 562 >NMB1762 [U] COG2831 Hemolysin activation/secretion protein Nme Neisseria meningitidis MC58 Length = 595 Score = 420 bits (1079), Expect = e-117, Method: Compositional matrix adjust. Identities = 238/581 (40%), Positives = 333/581 (57%), Gaps = 30/581 (5%) Query: 12 LAMLLASGSVQAQTTGTDIAANQEQLQRERERLLRQQQEQSPDVRLPAPKEVDVSTIFPV 71 LA ++A ++ A +I Q+ QR+RE LRQ + DVRL + Sbjct: 20 LAGIIAPATLLASPNPAEIRMQQDIQQRQREEQLRQTMQPESDVRLHQKNTGETVNQLMG 79 Query: 72 QES--PCFPISRISLIGEAAERFQFALSSVTGQGG-ALGSCLGTEGVNIVIAHMQNALIL 128 +S PCF I+ + L GE RFQFAL + G G CL +N +++ QNALI Sbjct: 80 DDSSQPCFAINEVVLEGEHHARFQFALKRALRETGFQAGKCLHAGNINQIMSLAQNALIG 139 Query: 129 RGYTTSQIRAATQDLKTGELVLTILPGHVRHIRFAPDASPRGTA------WNALPINAGD 182 RGYTT++I AA QDL +G+L LT++P ++R IR + A N P + D Sbjct: 140 RGYTTTRILAAPQDLNSGKLQLTLIPSYLRSIRIDRSNDDQTHAGRIAAFQNKFPTRSND 199 Query: 183 ILNLRDIEQGLENFKRVSTAQADIEVAPTEAAERPGDSDLVIRYQQSF-PFRFNVALDDG 241 +LNLRD+EQGLEN KR+ TA+AD+++ P E P SD+V++++Q P+R +V +D+ Sbjct: 200 LLNLRDLEQGLENLKRLPTAEADLQIVPVEG--EPNQSDVVVQWRQRLLPYRVSVGMDNS 257 Query: 242 GSKATGKYQAGATLSYDNWWTLNDLFYASWNRSLG----------HYGDHGVNSYTVHYS 291 GS+ATGKYQ T S DN L+D+FY ++ RS+G H + G N+Y VHYS Sbjct: 258 GSEATGKYQGNITFSADNPLGLSDMFYVNYGRSIGGTPDEESFDGHRKEGGSNNYAVHYS 317 Query: 292 VPAGYWMLGGTLSGSRYHQQVAGANNSIIYSGQSENAELKLSRLIYRDAVRKTTLSLKGL 351 P G W +G RYHQ V+G + Y+G+S N + +RL+YRDA RKT L +K Sbjct: 318 APFGKWTWAFNHNGYRYHQAVSGLSEVYDYNGKSYNTDFGFNRLLYRDAKRKTYLGVKLW 377 Query: 352 LRNSRNFIDDTEVGPQRHRTSAWEAGVNHREFIGDATVDANLVYRR--ALDKQGREPEST 409 +R ++++IDD E+ QR +T+ W A ++H+E+IG +T D L Y+R + R PE Sbjct: 378 MRETKSYIDDAELTVQRRKTAGWLAELSHKEYIGRSTADFKLKYKRGTGMKDALRAPEEA 437 Query: 410 ADLPQLATRYGLFVADATINAPFQIAGQRLRYNGSVRTQWNRGALPSQDQFAIGGRYTVR 469 + +R ++ A A +N PFQI Q Y+ SV QWN+ L SQD+ AIGG +TVR Sbjct: 438 --FGEGTSRMKIWTASADVNTPFQIGKQLFAYDTSVHAQWNKTPLTSQDKLAIGGHHTVR 495 Query: 470 GFDGELILQAERGWLVRNELALALGQGNQELYAGIDAGQVSGPSAQYLLGDRLAGAVIGL 529 GFDGE+ L AERGW RN+L+ G+Q LY G D G VSG SA++L G L G IG+ Sbjct: 496 GFDGEMSLSAERGWYWRNDLSWQFKPGHQ-LYLGADVGHVSGQSAKWLSGQTLVGTAIGI 554 Query: 530 RGAFW---TVSYDAFIARPLNKPDGFKTADVTGGFSVNLAF 567 RG + YD F R L KP+ F++ GF V F Sbjct: 555 RGQIKLGGNLHYDIFTGRALKKPEFFQSRKWASGFQVGYTF 595