BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0029.p (390 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1031 [H] COG1488 Nicotinic acid phosphoribosyltransferase Rso... 609 e-174 XF1097 [H] COG1488 Nicotinic acid phosphoribosyltransferase Xfa ... 554 e-157 NMA1706 [H] COG1488 Nicotinic acid phosphoribosyltransferase NmA... 415 e-116 NMB1505 [H] COG1488 Nicotinic acid phosphoribosyltransferase Nme... 412 e-115 PA4919 [H] COG1488 Nicotinic acid phosphoribosyltransferase Pae ... 385 e-107 >RSc1031 [H] COG1488 Nicotinic acid phosphoribosyltransferase Rso Ralstonia solanacearum Length = 404 Score = 609 bits (1570), Expect = e-174, Method: Compositional matrix adjust. Identities = 282/390 (72%), Positives = 325/390 (83%), Gaps = 1/390 (0%) Query: 1 MIISSLLDTDLYKFTMMQVVLHHFPGAQVEYRFKCRNDNVDLTPYIDEIKAEIAALCRLR 60 MII SLLDTDLYKFTMMQVVLHHFPGA VEYRFKCRN VDL PYI+ I+AEI LC LR Sbjct: 16 MIIRSLLDTDLYKFTMMQVVLHHFPGAHVEYRFKCRNPGVDLVPYIEAIRAEIRHLCSLR 75 Query: 61 FRESELAYLRSFRFIKSDFVDFLDLFHLNEKYISVTPSPAGNGEIEIQVKGPWLHTILFE 120 F E+EL YLR RFIKSDFVDFLDLFHL+EKYI + P+ + +G+I+I + GPWLHTI+FE Sbjct: 76 FTEAELDYLRGLRFIKSDFVDFLDLFHLSEKYIDIRPAASNDGQIDIVISGPWLHTIMFE 135 Query: 121 VPVLAIVNEVYFRATQRAPDYETGRARLRDKIALLTDNSLLEGCKIADYGTRRRFSRSWH 180 VPVLAIVNEVYF TQ P ++ G+ RL +K+A LT L E C+IADYGTRRRFS +WH Sbjct: 136 VPVLAIVNEVYFSRTQAHPQWDEGKRRLTEKLASLTRPGL-EDCRIADYGTRRRFSHTWH 194 Query: 181 AEVILAMKEHMGSHFAGTSNVQFAMQHDLTPLGTMAHEYLQACQALGPRLRDSQIYGFEM 240 V++ + +GS +AGTSNV FAM+H++TPLGTMAHEYLQACQ+LGPRLRDSQ++ E Sbjct: 195 EHVLMEARSQLGSQYAGTSNVYFAMKHNMTPLGTMAHEYLQACQSLGPRLRDSQVFALET 254 Query: 241 WAREYRGDLGIALSDVYGMDAFLRDFDMYFCKLFDGARHDSGDPFEWGERLLKHYDNNRV 300 WAREYRGDLGIALSD YG DAFLRDFDM+FCKLFDG RHDSGDPFEWGER+LKHY+ RV Sbjct: 255 WAREYRGDLGIALSDTYGFDAFLRDFDMFFCKLFDGVRHDSGDPFEWGERMLKHYEGMRV 314 Query: 301 DSKSKVLVFSDGLDFDKVVSLYLRFKDRAKVAFGVGTNLTNDLGYTPLQVVMKMVRCNGQ 360 D +SK L+FSD LD KVV LY RF+ R K+AFGVGTNLTNDLGYTPLQ+V+KMVRCNGQ Sbjct: 315 DPQSKALIFSDSLDMPKVVRLYERFRSRCKLAFGVGTNLTNDLGYTPLQIVIKMVRCNGQ 374 Query: 361 PVAKLSDTPAKNMCDDEAYVKYLRQVFEIK 390 PVAKLSD P K MCDD AY+ YL+QVF ++ Sbjct: 375 PVAKLSDAPEKTMCDDPAYLAYLKQVFGVQ 404 >XF1097 [H] COG1488 Nicotinic acid phosphoribosyltransferase Xfa Xylella fastidiosa 9a5c Length = 394 Score = 554 bits (1428), Expect = e-157, Method: Compositional matrix adjust. Identities = 262/389 (67%), Positives = 312/389 (80%), Gaps = 1/389 (0%) Query: 2 IISSLLDTDLYKFTMMQVVLHHFPGAQVEYRFKCRNDNVDLTPYIDEIKAEIAALCRLRF 61 II SLLDTDLYKFTMMQ VLH +PGAQVEYRFKCR VDL +I+EI EI LC LRF Sbjct: 4 IIKSLLDTDLYKFTMMQAVLHQYPGAQVEYRFKCRTPGVDLARFINEISHEIDGLCALRF 63 Query: 62 RESELAYLRSFRFIKSDFVDFLDLFHLNEKYISVTPSPAGNGEIEIQVKGPWLHTILFEV 121 + EL YLR RF+K DFVDFL LFHL+ KY+ + S +GEIE+ ++GPWLHTILFEV Sbjct: 64 SKEELDYLRGLRFMKPDFVDFLGLFHLDRKYLQLRASTQVSGEIELDIRGPWLHTILFEV 123 Query: 122 PVLAIVNEVYFRATQRAPDYETGRARLRDKIALLTDNSLLEGCKIADYGTRRRFSRSWHA 181 P+LAI+NEV+FR T + + GRARL K+ LL S E C IADYGTRRR+SR WHA Sbjct: 124 PLLAIINEVWFRNTSML-NLDVGRARLDAKVRLLKGESGYEECSIADYGTRRRYSRQWHA 182 Query: 182 EVILAMKEHMGSHFAGTSNVQFAMQHDLTPLGTMAHEYLQACQALGPRLRDSQIYGFEMW 241 E++ + + +GS+F GTSNV FA Q+ TPLGTMAHEYLQA QALGPRLRDSQ+ G E W Sbjct: 183 ELLPLLAQGLGSNFVGTSNVYFAKQYGYTPLGTMAHEYLQAFQALGPRLRDSQVAGLEAW 242 Query: 242 AREYRGDLGIALSDVYGMDAFLRDFDMYFCKLFDGARHDSGDPFEWGERLLKHYDNNRVD 301 AREYRGDLGIALSDV G+DAFL DFD+YFCKLFDG RHDSGDPF+WGER++ H +++R+D Sbjct: 243 AREYRGDLGIALSDVVGLDAFLGDFDLYFCKLFDGMRHDSGDPFKWGERIIMHLESHRID 302 Query: 302 SKSKVLVFSDGLDFDKVVSLYLRFKDRAKVAFGVGTNLTNDLGYTPLQVVMKMVRCNGQP 361 ++KVLVFSDGLD +KV+ LY F+ R ++AFGVGT+LTNDLG TPLQ+V+KMVRCNGQP Sbjct: 303 PRTKVLVFSDGLDMNKVMRLYQHFRGRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQP 362 Query: 362 VAKLSDTPAKNMCDDEAYVKYLRQVFEIK 390 VAKLSD+P K+MCDD AY+ YLRQVF + Sbjct: 363 VAKLSDSPGKSMCDDPAYLHYLRQVFGVS 391 >NMA1706 [H] COG1488 Nicotinic acid phosphoribosyltransferase NmA Neisseria meningitidis Z2491 Length = 419 Score = 415 bits (1067), Expect = e-116, Method: Compositional matrix adjust. Identities = 204/395 (51%), Positives = 270/395 (68%), Gaps = 9/395 (2%) Query: 2 IISSLLDTDLYKFTMMQVVLHHFPGAQVEYRFKCRNDNV--DLTPYIDEIKAEIAALCRL 59 II SLLDTDLYKFTM+QVVLH FP Y F+CRN + L ++++ E+ ALC+L Sbjct: 21 IIHSLLDTDLYKFTMLQVVLHQFPQTHSLYEFRCRNASTVYPLADIKEDLEVELDALCQL 80 Query: 60 RFRESELAYLRSFRFIKSDFVDFLDLFHLNEKYISVTPSPAGNGEIEIQVKGPWLHTILF 119 RF EL YLRS RFIKSDFVD+L+LF L +++ V G + I+++GP + + F Sbjct: 81 RFTHDELDYLRSLRFIKSDFVDYLELFQLQRRFVEVGTD--DKGRLNIRIEGPMIQAMFF 138 Query: 120 EVPVLAIVNEVYFRATQRAPDYETGRARLRDKIALLTDNSLLEGCK-----IADYGTRRR 174 E+ +LAIVNE+YFR + E G RL+ K A L + + + I+D+GTRRR Sbjct: 139 EIFILAIVNELYFRRLETPAVIEEGERRLQAKAARLKEIAAAQNPDEPPFLISDFGTRRR 198 Query: 175 FSRSWHAEVILAMKEHMGSHFAGTSNVQFAMQHDLTPLGTMAHEYLQACQALGPRLRDSQ 234 + +W VI + E S GTSNV A + +TP+GTMAHE+LQA QAL RLR+ Q Sbjct: 199 YKLAWQEHVIRTLLEAAPSIVRGTSNVFLAKKLGITPIGTMAHEFLQAFQALDVRLRNFQ 258 Query: 235 IYGFEMWAREYRGDLGIALSDVYGMDAFLRDFDMYFCKLFDGARHDSGDPFEWGERLLKH 294 E W EYRGDLG+AL+DV GMDAFLRDFD+YF KLFDG RHDSGDP+ WG++ H Sbjct: 259 KAALESWVHEYRGDLGVALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYIWGDKAYAH 318 Query: 295 YDNNRVDSKSKVLVFSDGLDFDKVVSLYLRFKDRAKVAFGVGTNLTNDLGYTPLQVVMKM 354 Y ++DS++K+L FSDGLD ++ +L+ FKDR K FG+GTNLTND+G+TPL +V+K+ Sbjct: 319 YQKLKIDSRTKMLTFSDGLDIERSWALHQYFKDRFKTGFGIGTNLTNDMGHTPLNIVLKL 378 Query: 355 VRCNGQPVAKLSDTPAKNMCDDEAYVKYLRQVFEI 389 V CNGQ VAKLSD+P K M ++ ++ YLRQVF++ Sbjct: 379 VECNGQSVAKLSDSPGKTMTNNSTFLAYLRQVFDV 413 >NMB1505 [H] COG1488 Nicotinic acid phosphoribosyltransferase Nme Neisseria meningitidis MC58 Length = 402 Score = 412 bits (1060), Expect = e-115, Method: Compositional matrix adjust. Identities = 202/395 (51%), Positives = 269/395 (68%), Gaps = 9/395 (2%) Query: 2 IISSLLDTDLYKFTMMQVVLHHFPGAQVEYRFKCRNDNV--DLTPYIDEIKAEIAALCRL 59 II SLLDTDLYKFTM+QVVLH FP Y F+CRN + L ++++AE+ ALC+L Sbjct: 4 IIHSLLDTDLYKFTMLQVVLHQFPQTHSLYEFRCRNASTVYPLADIREDLEAELDALCQL 63 Query: 60 RFRESELAYLRSFRFIKSDFVDFLDLFHLNEKYISVTPSPAGNGEIEIQVKGPWLHTILF 119 RF EL YLRS RFIKSDFVD+L+LF L +++ + + I+++GP + + F Sbjct: 64 RFTHDELGYLRSLRFIKSDFVDYLELFQLQRRFVEIGTD--DKDRLNIRIEGPMIQAMFF 121 Query: 120 EVPVLAIVNEVYFRATQRAPDYETGRARLRDKIALLTDNSLLEGCK-----IADYGTRRR 174 E+ +LAIVNE+YFR + E G RL+ K A L + + + I+D+GTRRR Sbjct: 122 EIFILAIVNELYFRRLETPAVIEEGERRLQAKAARLKEIAAAQNPDEPPFLISDFGTRRR 181 Query: 175 FSRSWHAEVILAMKEHMGSHFAGTSNVQFAMQHDLTPLGTMAHEYLQACQALGPRLRDSQ 234 + +W VI + E GTSNV A + +TP+GTMAHE+LQA QAL RLR+ Q Sbjct: 182 YKLAWQEHVIRTLLEAAPGIVRGTSNVFLAKKLGITPIGTMAHEFLQAFQALDVRLRNFQ 241 Query: 235 IYGFEMWAREYRGDLGIALSDVYGMDAFLRDFDMYFCKLFDGARHDSGDPFEWGERLLKH 294 E W EYRGDLG+AL+DV GMDAFLRDFD+YF KLFDG RHDSGDP+ WG++ H Sbjct: 242 KAALESWVHEYRGDLGVALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYVWGDKAYAH 301 Query: 295 YDNNRVDSKSKVLVFSDGLDFDKVVSLYLRFKDRAKVAFGVGTNLTNDLGYTPLQVVMKM 354 Y ++DS++K+L FSDGLD ++ +L+ FKDR K FG+GTNLTND+G+TPL +V+K+ Sbjct: 302 YQKLKIDSRTKMLTFSDGLDIERSWALHQYFKDRFKTGFGIGTNLTNDMGHTPLNIVLKL 361 Query: 355 VRCNGQPVAKLSDTPAKNMCDDEAYVKYLRQVFEI 389 V CNGQ VAKLSD+P K M ++ ++ YLRQVF++ Sbjct: 362 VECNGQSVAKLSDSPGKTMTNNSTFLAYLRQVFDV 396 >PA4919 [H] COG1488 Nicotinic acid phosphoribosyltransferase Pae Pseudomonas aeruginosa Length = 399 Score = 385 bits (989), Expect = e-107, Method: Compositional matrix adjust. Identities = 194/392 (49%), Positives = 252/392 (64%), Gaps = 8/392 (2%) Query: 2 IISSLLDTDLYKFTMMQVVLHHFPGAQVEYRFKCRNDNVDLTPYIDEIKAEIAALCRLRF 61 I+ +LLDTD YK TMMQ VLH++P A+VE+ F+CRN DL PY+ EI+ +I L + Sbjct: 10 IVQNLLDTDFYKLTMMQAVLHNYPNAEVEWEFRCRNAE-DLRPYLAEIRYQIERLAEVEV 68 Query: 62 RESELAYLRSFRFIKSDFVDFLDLFHLNEKYISVTPSPAGNGEIEIQVKGPWLHTILFEV 121 +LA+L F+K DF+ FL LF N +Y+ + +G++ I+++GPWLH ILFEV Sbjct: 69 TADQLAFLERIPFMKPDFIRFLSLFRFNLRYVH---TGIEDGQLAIRLRGPWLHVILFEV 125 Query: 122 PVLAIVNEVYFRATQRAPDYETGRARLRDKIALLTDNSLLEGC---KIADYGTRRRFSRS 178 P+LAIV+EV R R E +L K+ L+ + E ++AD+GTRRRFS Sbjct: 126 PLLAIVSEVRNRYRYREVVLEQVGEQLYRKLDWLSAQASSEELAEFQVADFGTRRRFSYR 185 Query: 179 WHAEVILAMKEHMGSHFAGTSNVQFAMQHDLTPLGTMAHEYLQACQALGPRLRDSQIYGF 238 EV+ +K F GTSNV A ++DL P+GTMAHE+L A Q LGPRL DSQ Sbjct: 186 TQEEVVHILKRDFPGRFVGTSNVHLAREYDLKPIGTMAHEWLMAHQQLGPRLVDSQQAAL 245 Query: 239 EMWAREYRGDLGIALSDVYGMDAFLRDFDMYFCKLFDGARHDSGDPFEWGERLLKHYDNN 298 + W REYRG LGIAL+D MDAFL DFD+YF KLFDG RHDSGDP W E+ + HY Sbjct: 246 DCWVREYRGQLGIALTDCITMDAFLDDFDLYFAKLFDGLRHDSGDPLAWAEKAIAHYRRL 305 Query: 299 RVDSKSKVLVFSDGLDFDKVVSLYLRFKDRAKVAFGVGTNLTNDL-GYTPLQVVMKMVRC 357 +D SK LVFSDGLD K + L+ + + V+FG+GTNLT D+ G P+ +V+KM C Sbjct: 306 GIDPLSKTLVFSDGLDMPKALQLFRALRGKINVSFGIGTNLTCDIPGVEPMNIVLKMTAC 365 Query: 358 NGQPVAKLSDTPAKNMCDDEAYVKYLRQVFEI 389 NG PVAK+SD P K C DE +V YLR VF + Sbjct: 366 NGHPVAKISDAPGKTQCRDENFVAYLRHVFNV 397