BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0010.0014.p         (232 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc0713_2 [H] COG0807 GTP cyclohydrolase II Rso Ralstonia solana...   194   1e-49
RSc0713_1 [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synth...   118   1e-26
NMB1256_1 [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synth...   110   3e-24
NMA1429_1 [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synth...   110   4e-24
NMB1256_2 [H] COG0807 GTP cyclohydrolase II Nme Neisseria mening...   108   1e-23

>RSc0713_2 [H] COG0807 GTP cyclohydrolase II Rso Ralstonia solanacearum
          Length = 173

 Score =  194 bits (493), Expect = 1e-49,   Method: Compositional matrix adjust.
 Identities = 93/166 (56%), Positives = 127/166 (76%), Gaps = 3/166 (1%)

Query: 66  SIIERVAEREMHTVHGSFKAIAYRDTPSGGAHLALVHGDIRPGEETLVRVHQPVSILDLL 125
           SI+ER+ ER M T  G+F+A+A+RD  +G AHLALV G   P  ETLVRVH+P+S+LDLL
Sbjct: 1   SIVERIGERNMETQFGTFRAVAFRDHAAGRAHLALVKGTPTPATETLVRVHEPLSVLDLL 60

Query: 126 ETKATTHSWNMASAMAAIKAAPSGVVVLLNCEESADQMFAQFTALNNVQAAKPARADRLD 185
           E + TTHSW++ +A+ A++AAP+GVVVLLNC +S +++F QF+AL+  Q    ++ D   
Sbjct: 61  ECQRTTHSWSVPAALRAVQAAPTGVVVLLNCGDSPERLFTQFSALDAPQERPRSKPDP-- 118

Query: 186 LRTYGIGAQILKDLGVCKMQLLASPRKMPSMTGFNLEVTGYRAKPD 231
            R YGIGAQILKD+GV KM++LASP K+PSM G++LEVT Y++  D
Sbjct: 119 -RIYGIGAQILKDVGVGKMRVLASPLKLPSMAGYDLEVTAYQSMAD 163


>RSc0713_1 [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase Rso
           Ralstonia solanacearum
          Length = 226

 Score =  118 bits (295), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 54/65 (83%), Positives = 59/65 (90%)

Query: 1   MRAGHTEAGCDLTQMAGLTPAAVICEILKDDGTMARLPDLLEFAEEHKLKIGTIADLIHY 60
           MRAGHTEAGCDL  +AGLTPA+VICEI+KDDGTMARLPDL+EFA EH LKIGTIADLI Y
Sbjct: 162 MRAGHTEAGCDLASLAGLTPASVICEIMKDDGTMARLPDLVEFAREHGLKIGTIADLIQY 221

Query: 61  RSQHE 65
           RS+ E
Sbjct: 222 RSRTE 226


>NMB1256_1 [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase Nme
           Neisseria meningitidis MC58
          Length = 204

 Score =  110 bits (275), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 50/65 (76%), Positives = 58/65 (89%)

Query: 1   MRAGHTEAGCDLTQMAGLTPAAVICEILKDDGTMARLPDLLEFAEEHKLKIGTIADLIHY 60
           +RAGHTEAG DL QM GL PA+VICEI+ DDGTMAR+P+L++FAEEHKLKIGTIADLI Y
Sbjct: 140 VRAGHTEAGVDLAQMNGLIPASVICEIINDDGTMARMPELMKFAEEHKLKIGTIADLIEY 199

Query: 61  RSQHE 65
           RS+ E
Sbjct: 200 RSRTE 204


>NMA1429_1 [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase NmA
           Neisseria meningitidis Z2491
          Length = 204

 Score =  110 bits (274), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 50/65 (76%), Positives = 57/65 (87%)

Query: 1   MRAGHTEAGCDLTQMAGLTPAAVICEILKDDGTMARLPDLLEFAEEHKLKIGTIADLIHY 60
           +RAGHTEAG DL QM GL PAAVICEI+ DDGTMAR+P+L++FAEEHKLKIGTI DLI Y
Sbjct: 140 VRAGHTEAGVDLAQMNGLIPAAVICEIINDDGTMARMPELMKFAEEHKLKIGTITDLIEY 199

Query: 61  RSQHE 65
           RS+ E
Sbjct: 200 RSRTE 204


>NMB1256_2 [H] COG0807 GTP cyclohydrolase II Nme Neisseria meningitidis MC58
          Length = 159

 Score =  108 bits (270), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 61/162 (37%), Positives = 88/162 (54%), Gaps = 7/162 (4%)

Query: 66  SIIERVAEREMHTVHGSFKAIAYRDTPSGGAHLALVHGDIRPGEETLVRVHQPVSILDLL 125
           S++E +    + T  G F+   Y D  SG  HLALV G      ETLVRVH+P S++D +
Sbjct: 1   SLLEDMGNAPVQTPWGEFQQHVYVDKLSGETHLALVKGTPAADTETLVRVHEPFSVMDFI 60

Query: 126 ETKATTHSWNMASAMAAIKAAPSGVVVLLNCEESADQMFAQFTALNNVQAAKPARADRLD 185
           +     HSW++  A+  I+ A SGVV+LL+  E    +      L+        +A + D
Sbjct: 61  QANP-RHSWSLPKALEHIQQAESGVVILLHRTEDGASL------LDRTLPKGANQAYKWD 113

Query: 186 LRTYGIGAQILKDLGVCKMQLLASPRKMPSMTGFNLEVTGYR 227
            ++YGIGAQIL  L V K+++L  P     +TGF LEV G+ 
Sbjct: 114 SKSYGIGAQILAGLNVKKLRVLGQPSSFTGLTGFGLEVVGFE 155