BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0010.0005.p (1049 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1055 0.0 RSp1198 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1040 0.0 mll5779 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobi... 1026 0.0 PA1436 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1016 0.0 PA2527 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1015 0.0 >RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1033 Score = 1055 bits (2729), Expect = 0.0, Method: Compositional matrix adjust. Identities = 547/1026 (53%), Positives = 726/1026 (70%), Gaps = 24/1026 (2%) Query: 1 VSVSATFIKRPIGTTLLALAILLVGIAVWPLLPVAPLPQVDFPTIQVSASLPGGSPETMA 60 +++SATFI RP+ T LL + + L GIA + LLPV+PLPQVDFPTI V+ASLPG SPETMA Sbjct: 1 MNLSATFIARPVATALLTIGVALAGIAAFNLLPVSPLPQVDFPTISVNASLPGASPETMA 60 Query: 61 SNVAQPLERQFSLIAGLSQMTSQSALGSTQITLQFDLNRNIDAAALDVQAAINASTGQLP 120 + VA PLER IAG+++MTSQSALGST++TLQFDL+R+ID AA DVQAAINAS LP Sbjct: 61 ATVATPLERSLGRIAGITEMTSQSALGSTRVTLQFDLSRDIDGAARDVQAAINASRSLLP 120 Query: 121 SNLPNPPTFRKVNPADSPIMIMSVQSDALPLTQVSDFADNILAQQISQISGVGLVNVNGA 180 S LP+ PT+RKVNPAD+PIMI+ + SD ++ D A ILAQ++SQI+GVG VN+ GA Sbjct: 121 SGLPSNPTYRKVNPADAPIMILGLTSDTKSRGELYDAASTILAQKLSQITGVGQVNIGGA 180 Query: 181 QKPAVRIQVDPAKLATLNLSLEDIRGVIATTTVNQPKGTVDGTHQSFTVYTNDQLLSADP 240 PAVR++++P L +S E +R VI T N+PKG ++ ++ +T+Y NDQ A+ Sbjct: 181 SLPAVRVELNPTALNKYGISTETVRTVITATNANKPKGMLEAGNRVWTLYANDQARHAEE 240 Query: 241 WNDMVLAYRAGAPIHVRDIGVAIDAPENMKIAAWAFSGAAAETDTTLTNGR-SIVLAITA 299 + +++AYR GAP+ + D+ D+ ++++ A NG+ S++L I Sbjct: 241 YKPLIIAYRNGAPVRLSDVAEVTDSVQDIRNYGSA-------------NGKPSVLLIINR 287 Query: 300 MP--RLRAAIPXIKAAMPRLRAAIPASVHVNTLIDRTQTIRASVEDVEFTLVLTIALVVM 357 P + + I A +P LR IPA ++++ ++DRT TIRAS+ DVE TL+L+I LV+M Sbjct: 288 QPGANIIDTVDRINAILPYLRNTIPAQINLDVMMDRTPTIRASLRDVERTLMLSIGLVIM 347 Query: 358 VIFVFLRNIAATLIPSITVPLAIMGTAAVMYLVGYSLDNLSLMALTIAVGFVVDDAIVML 417 V+++FLRN+ ATLIPS+ VP++++GT VMYL GYSLDNLSLMALT+A GFVVDDAIV+L Sbjct: 348 VVYLFLRNLRATLIPSVAVPVSLIGTFGVMYLCGYSLDNLSLMALTVATGFVVDDAIVVL 407 Query: 418 ENIYRYVEEGMSPMEAALKGSSEIGFTIISISVSLVAVFIPLLLMGGIVGRLFREFAVTV 477 EN+ R++E GM PM+AALKG+ E+GFT++S+S SL+AVFIPLL+MGGIVGRLFREFAVT+ Sbjct: 408 ENVSRHIENGMRPMQAALKGAREVGFTVVSMSFSLIAVFIPLLMMGGIVGRLFREFAVTL 467 Query: 478 TLTIGVSVIISLTLTPMLCSRFLKNSHAEQHGKMYQLFERFFDALLNGYKRGLDLVLRHQ 537 ++ I VS+ ISLT TPM+C+R LK + E+ G ++ E FF+ LL+GY+ L LRH Sbjct: 468 SVAILVSLAISLTTTPMMCARLLKPASEEEPGWFHRKTEGFFNLLLDGYRHSLAWALRHS 527 Query: 538 FITLMSFLATVAVTVALFIFIPKGFFPQQDNGVIAGFAESAQDISSSAMHRRLLQVADVV 597 ++TL+ LATV + L++ +PKGFFPQQD G + GF ++ Q IS AM +L+ +V Sbjct: 528 WLTLLILLATVCLNGYLYVVVPKGFFPQQDVGRLMGFIQADQAISFQAMRTKLVDFIHIV 587 Query: 598 RKDPDVTGFAMSAGSTTFNTGNFFIALKPKSEGRTLDASEIITHLRPQVAKIQGVNLFMQ 657 ++DP V G + N+G FI LKP +E R L A ++I LR ++A+ G NLF+Q Sbjct: 588 QQDPAVENVVGFTGGSQINSGQMFIQLKPLAE-RKLSADQVINRLRGKLAREPGANLFLQ 646 Query: 658 ASQDINVGGRLSRTQYQYTLTDSNLDELNVWAPKLVDRLRRLKQLTDVASDQQNSAATAT 717 A QDI +GGR S QYQYTL NL+EL W PK+ L ++K L DV +D Q+ Sbjct: 647 AVQDIRIGGRPSNAQYQYTLQADNLEELRAWEPKIRQALTQIKSLVDVNTDAQDKGQQTA 706 Query: 718 ITIDRARASSFGISPALIDATIYDAIGQRQVAQYFTQVNSYRVILEVTPELQKDPALFNK 777 + DR +A + GI+P ID + +A GQRQV+ + +N YRV++E P+ ++P Sbjct: 707 LVFDRDKAMALGITPKDIDNALNNAFGQRQVSTIYNPLNQYRVVMEAAPQYWQNPEGLRD 766 Query: 778 LYLTSPLTGQQVPLSTFIKVDTTKTAYLSISHQSQFPAVTISFNLAHGVALGEAVDAINQ 837 +YL + +G QVPLSTF T T L+++HQ QF A T+SFNLA G +L A I Sbjct: 767 IYLITA-SGAQVPLSTFSHYGPTNTP-LAVNHQGQFAASTLSFNLAPGASLSAATQQIQD 824 Query: 838 AQAEMGVPTTLTGAFQGTAKAFGDSLSSQPYLIAAALIAVYIVLGLLYESYIHPLTILST 897 A +GVPTT+ G+FQGTA+AF DSLSSQP LI ALI +YIVLG+LYESY+HP+TILST Sbjct: 825 AMNRIGVPTTVHGSFQGTARAFQDSLSSQPVLILFALITIYIVLGVLYESYVHPITILST 884 Query: 898 LPSAGVGALLILMAGGYDLSVIALIGI-----IXKKNGIMMIDFALTAERQHGMKPEEAI 952 LPSAGVGALL L+ D SVIALIG+ I KKN IMMIDFAL AER GM P +AI Sbjct: 885 LPSAGVGALLALIVTDTDFSVIALIGVILLIGIVKKNAIMMIDFALEAERSQGMSPADAI 944 Query: 953 YQACLLRFRPIMMTTMCALLSGLPLMLGHGAGSELRRPLGYAMVGGLVLSQALTLFTTPV 1012 + AC+LRFRPI+MTTM ALL LPL LGHG G+ELR+PLG ++VGGL++SQ LTL+TTPV Sbjct: 945 FHACVLRFRPILMTTMAALLGALPLALGHGDGAELRQPLGISIVGGLLVSQILTLYTTPV 1004 Query: 1013 VYLYLD 1018 VYL LD Sbjct: 1005 VYLALD 1010 >RSp1198 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1041 Score = 1040 bits (2689), Expect = 0.0, Method: Compositional matrix adjust. Identities = 539/1051 (51%), Positives = 734/1051 (69%), Gaps = 23/1051 (2%) Query: 4 SATFIKRPIGTTLLALAILLVGIAVWPLLPVAPLPQVDFPTIQVSASLPGGSPETMASNV 63 S FI RP+ TTLL +AILL G+ + +LP++ LP+VD+PTIQV+ PG SP+ M S++ Sbjct: 4 SRIFILRPVATTLLMVAILLSGLVAYRMLPLSALPEVDYPTIQVTTLYPGASPDVMTSSI 63 Query: 64 AQPLERQFSLIAGLSQMTSQSALGSTQITLQFDLNRNIDAAALDVQAAINASTGQLPSNL 123 PLERQF + GL QMTS S+ G++ ITLQFDL+ ++D A +VQAAINA+ LP++L Sbjct: 64 TAPLERQFGQMPGLKQMTSASSGGASVITLQFDLSLSLDIAEQEVQAAINAAGNLLPTDL 123 Query: 124 PNPPTFRKVNPADSPIMIMSVQSDALPLTQVSDFADNILAQQISQISGVGLVNVNGAQKP 183 P PP + KVNPAD+PI+ +++ S LPL ++ D D +AQ++SQ+ G+GLV+++G Q+P Sbjct: 124 PMPPIYSKVNPADAPILTLAITSRTLPLPKLEDIVDTRVAQKLSQLPGIGLVSISGGQRP 183 Query: 184 AVRIQVDPAKLATLNLSLEDIRGVIATTTVNQPKGTVDGTHQSFTVYTNDQLLSADPWND 243 AVRIQ + LA L LS++DIR I VN KG+ DG ++ T+ NDQL SA + Sbjct: 184 AVRIQANTQALAALGLSIDDIRTAIGNANVNGAKGSFDGPMRASTIDANDQLRSAAEYGT 243 Query: 244 MVLAYRAGAPIHVRDIGVAIDAPENMKIAAWAFSGAAAETDTTLTNGRSIVLAITAMPRL 303 M++AY+ GAPI + D+ ID EN K+AAWA + A + G +++ + Sbjct: 244 MIVAYKNGAPIRLTDVAQIIDGAENSKLAAWANTTPAIILNVQRQPGANVIDVVN----- 298 Query: 304 RAAIPXIKAAMPRLRAAIPASVHVNTLIDRTQTIRASVEDVEFTLVLTIALVVMVIFVFL 363 RA KA +P+L+ +PA++ V L DRT TIRASV DV+F L+L +ALVVMVIF+FL Sbjct: 299 RA-----KALLPQLKDTLPANIDVAVLTDRTTTIRASVADVQFELLLAVALVVMVIFLFL 353 Query: 364 RNIAATLIPSITVPLAIMGTAAVMYLVGYSLDNLSLMALTIAVGFVVDDAIVMLENIYRY 423 RNI AT+IP++ VPL+++GT VMYL G+S++NL+LMALTIA GFVVDDAIVM+ENI RY Sbjct: 354 RNIPATIIPAVAVPLSLVGTFGVMYLAGFSVNNLTLMALTIATGFVVDDAIVMIENIARY 413 Query: 424 VEEGMSPMEAALKGSSEIGFTIISISVSLVAVFIPLLLMGGIVGRLFREFAVTVTLTIGV 483 +E+G PMEAALKG+ +IGFTIIS++ SL+AV IPLL M +VGRLFREFA+T+ ++I + Sbjct: 414 IEDGDPPMEAALKGARQIGFTIISLTFSLIAVLIPLLFMSDVVGRLFREFAITLAVSILI 473 Query: 484 SVIISLTLTPMLCSRFLKNSHAEQHGKMYQLFERFFDALLNGYKRGLDLVLRHQFITLMS 543 S ++SLTLTPM+C+R L++ + + Y +FFD ++ Y R L VL Q TL+ Sbjct: 474 SAVVSLTLTPMMCARLLRHIPEPEQTRFYHAAGQFFDNVIAQYGRMLQWVLDRQRTTLLV 533 Query: 544 FLATVAVTVALFIFIPKGFFPQQDNGVIAGFAESAQDISSSAMHRRLLQVADVVRKDPDV 603 + T+A+T L++++PKGFFP QD GVI G +++ Q IS AM R ++A+V+ KDP V Sbjct: 534 AIGTLALTGLLYVYVPKGFFPVQDTGVIQGISDATQSISFPAMAERQQKLAEVILKDPAV 593 Query: 604 TGFAMSAG----STTFNTGNFFIALKPKSEGRTLDASEIITHLRPQVAKIQGVNLFMQAS 659 + G +TT N+G I LKPK + R DA+EII L+P++AK+ G++LFMQ Sbjct: 594 ESLSSFIGVDGTNTTLNSGRMLINLKPK-DARDADATEIIQRLQPELAKVGGISLFMQPV 652 Query: 660 QDINVGGRLSRTQYQYTLTDSNLDELNVWAPKLVDRLRRLKQLTDVASDQQNSAATATIT 719 QD+ + R+SRTQYQ+T+ D + + L+ W P+LV+RL++ +L DVASD Q++ A + Sbjct: 653 QDLTIEDRVSRTQYQFTVEDPDPNNLSKWVPRLVERLQQTGELRDVASDLQDNGLRAYVQ 712 Query: 720 IDRARASSFGISPALIDATIYDAIGQRQVAQYFTQVNSYRVILEVTPELQKDPALFNKLY 779 IDR +A+ +G++ A +D+ +Y A GQR ++ FTQ N YRV+LE P+LQK P L Sbjct: 713 IDRDKAAVYGVTTAAVDSALYSAYGQRLISTIFTQSNQYRVVLEAAPQLQKGPQSLYDLR 772 Query: 780 LTSPLTGQQVPLSTFIKVDTTKTAYLSISHQSQFPAVTISFNLAHGVALGEAVDAINQAQ 839 + S GQQVPL F V + L ++HQ QFP+ TISFNLA G +LG AVDAIN A+ Sbjct: 773 VAS-TGGQQVPLGAFATV-VEQPGSLVVNHQGQFPSATISFNLARGASLGAAVDAINAAE 830 Query: 840 AEMGVPTTLTGAFQGTAKAFGDSLSSQPYLIAAALIAVYIVLGLLYESYIHPLTILSTLP 899 +G+P ++ +FQG A AF SLS++ +LI AA+I +YIVLG+LYES IHP+TILSTLP Sbjct: 831 QAIGLPASMQTSFQGAALAFQSSLSNELWLILAAIITMYIVLGVLYESTIHPVTILSTLP 890 Query: 900 SAGVGALLILMAGGYDL-----SVIALIGIIXKKNGIMMIDFALTAERQHGMKPEEAIYQ 954 SAGVGALL L+ G D+ I L+ I KKN IMMIDFAL AER+ GM P +AIYQ Sbjct: 891 SAGVGALLSLLVSGKDMGIIAIIGIILLIGIVKKNAIMMIDFALEAEREQGMAPRDAIYQ 950 Query: 955 ACLLRFRPIMMTTMCALLSGLPLMLGHGAGSELRRPLGYAMVGGLVLSQALTLFTTPVVY 1014 ACLLRFRPI+MTTM ALL LPLMLG G GSELR+PLG MVGGL++SQ LTLFTTPV+Y Sbjct: 951 ACLLRFRPILMTTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIY 1010 Query: 1015 LYLDRAHYWYMNKKEARAARK-AARKGGAAP 1044 L D + + +E RAAR+ A + G+ P Sbjct: 1011 LAFDSLGHRLRDWRERRAARRTGADQSGSQP 1041 >mll5779 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobium loti Length = 1038 Score = 1026 bits (2654), Expect = 0.0, Method: Compositional matrix adjust. Identities = 556/1044 (53%), Positives = 739/1044 (70%), Gaps = 20/1044 (1%) Query: 1 VSVSATFIKRPIGTTLLALAILLVGIAVWPLLPVAPLPQVDFPTIQVSASLPGGSPETMA 60 +SVS F++RPI T LL L I+LVG+ + LLP++ LPQVDFPTI V ++LPG ETMA Sbjct: 1 MSVSNIFVQRPIATGLLTLGIVLVGMVAYMLLPISSLPQVDFPTIAVESTLPGAKAETMA 60 Query: 61 SNVAQPLERQFSLIAGLSQMTSQSALGSTQITLQFDLNRNIDAAALDVQAAINASTGQLP 120 S VA PLE+QFS I GL+QMTS S LG T +TLQFDL+RNID+AA DVQAAINA++G LP Sbjct: 61 STVASPLEQQFSTIPGLAQMTSTSTLGKTDMTLQFDLSRNIDSAAQDVQAAINAASGSLP 120 Query: 121 SNLPNPPTFRKVNPADSPIMIMSVQSDALPLTQVSDFADNILAQQISQISGVGLVNVNGA 180 + +PPT+ KVNPA ++ + +QSD +PL V D A N++AQ +SQI G G V++ G+ Sbjct: 121 KAMQSPPTYHKVNPALFTVISIVLQSDTIPLPLVMDAASNMVAQTLSQIPGAGFVDMPGS 180 Query: 181 QKPAVRIQVDPAKLATLNLSLEDIRGVIATTTVNQPKGTVDGTHQSFTVYTNDQLLSADP 240 K A+RIQ+DP KLA+L +SLED+R + T N PKGT++G +S T+ N+QLL++ Sbjct: 181 SKSAIRIQLDPMKLASLGMSLEDVRSALVVGTTNGPKGTLEGAQRSVTLDANNQLLTSAD 240 Query: 241 WNDMVLAYRAGAPIHVRDIGVAIDAPENMKIAAWAFSGAAAETDTTLTNGRSIVLAITAM 300 + ++AYR G+PI + DIG AID+ EN + AW + A D L +G + V + Sbjct: 241 ASAAIIAYRNGSPIRISDIGRAIDSVENTTLGAWYNNRKAVLIDVHLQSGANAVDVVNG- 299 Query: 301 PRLRAAIPXIKAAMPRLRAAIPASVHVNTLIDRTQTIRASVEDVEFTLVLTIALVVMVIF 360 +KAA+P LR +P SV + T D T +RA+V DV+FTL++TI LVV+ IF Sbjct: 300 ---------VKAALPGLRLRLPPSVQIMTAGDSTVAVRAAVADVQFTLMITIGLVVLTIF 350 Query: 361 VFLRNIAATLIPSITVPLAIMGTAAVMYLVGYSLDNLSLMALTIAVGFVVDDAIVMLENI 420 +FL++++AT+IP++T+P++++GT VMYL+GYSLDN+SLM LTIAVGFVVDDAIV++ENI Sbjct: 351 LFLKSMSATIIPAVTIPVSLIGTFGVMYLLGYSLDNISLMGLTIAVGFVVDDAIVVIENI 410 Query: 421 YRYVEEGMSPMEAALKGSSEIGFTIISISVSLVAVFIPLLLMGGIVGRLFREFAVTVTLT 480 R++E G SP+EA LKG+SEIGFT++S++ SL+AVFIPLLLM +VGRLFREF+VT+ + Sbjct: 411 VRHIEGGESPLEATLKGASEIGFTVVSMTASLIAVFIPLLLMSSMVGRLFREFSVTIAVA 470 Query: 481 IGVSVIISLTLTPMLCSRFLK-NSHAEQHGKMYQLFERFFDALLNGYKRGLDLVLRHQFI 539 + +S ++SLTLTPM+C+ +K + H + ++ L ER FD + GY R L +V+ H + Sbjct: 471 LIISALVSLTLTPMMCALMIKGHGHEAKPNRLSSLLERGFDFIQRGYSRSLRVVVGHPRL 530 Query: 540 TLMSFLATVAVTVALFIFIPKGFFPQQDNGVIAGFAESAQDISSSAMHRRLLQVADVVRK 599 L+ F AT+AVT LF+ IPKGFFPQQD G+I+G ++AQDIS AM + V D++ K Sbjct: 531 VLLCFFATLAVTAELFLAIPKGFFPQQDLGLISGSTQAAQDISFQAMAAKQQAVVDLILK 590 Query: 600 DPDV-TGFAMSAGSTTFNTGNFFIALKPKSEGRTLDASEIITHLRPQVAKIQGVNLFMQA 658 DP V T + GS N+GN I LKP SE R++ A ++I LR + A + GV++ MQA Sbjct: 591 DPAVDTVRSTLGGSGRMNSGNLQIVLKPLSE-RSVSADQVIARLRKETAGVSGVSVGMQA 649 Query: 659 SQDINVGGRLSRTQYQYTLTDSNLDELNVWAPKLVDRLRRLKQLTDVASDQQNSAATATI 718 Q INVG R S+TQ+QYTL D NL EL WA + LR+L Q+ DVA+D Q A A+I Sbjct: 650 VQGINVGARGSQTQFQYTLQDPNLPELYRWADTMTAELRKLPQVRDVANDLQAVAPHASI 709 Query: 719 TIDRARASSFGISPALIDATIYDAIGQRQVAQYFTQVNSYRVILEVTPELQKDPALFNKL 778 +DR AS GI+P ID T+YDA GQRQV FTQ + +++++E+ P+ + D + + Sbjct: 710 AVDRDTASRLGITPQAIDDTLYDAFGQRQVTTIFTQADQHKIVMEIDPKYRVDAGALDAI 769 Query: 779 YLTSPLTGQQVPLSTFIKVDTTKTAYLSISHQSQFPAVTISFNLAHGVALGEAVDAINQA 838 Y+ S +G+QVPLS F KV ++ A L+I+HQ FP+VT+SFNLA VALG+AV A+ Sbjct: 770 YVGSN-SGKQVPLSAFAKV-SSSVAPLTINHQGLFPSVTLSFNLAPNVALGDAVTAVEAM 827 Query: 839 QAEMGVPTTLTGAFQGTAKAFGDSLSSQPYLIAAALIAVYIVLGLLYESYIHPLTILSTL 898 QA + + T+ FQGTA+AF SLS+QP LI AALIAVYIVLG+LYES IHP+TILSTL Sbjct: 828 QARIRMSATVQTGFQGTAQAFQASLSTQPMLIVAALIAVYIVLGMLYESVIHPITILSTL 887 Query: 899 PSAGVGALLILMAGGYDLSVIALIGI-----IXKKNGIMMIDFALTAERQHGMKPEEAIY 953 PSAGVGAL LM G L V+ L+GI I KKN IMMIDFAL+AER G+ P+EAI Sbjct: 888 PSAGVGALATLMLVGGQLDVMGLVGIILLIGIVKKNAIMMIDFALSAERDRGLPPKEAII 947 Query: 954 QACLLRFRPIMMTTMCALLSGLPLMLGHGAGSELRRPLGYAMVGGLVLSQALTLFTTPVV 1013 QAC+LRFRPI MTT+CALL LPL LG G GSELRRPLG A+VGGL +SQ LTL+TTPV+ Sbjct: 948 QACILRFRPITMTTLCALLGALPLALGTGVGSELRRPLGIAIVGGLCVSQLLTLYTTPVI 1007 Query: 1014 YLYLDRAHYWYMNKKEARAARKAA 1037 YLY+ + M K R+ A Sbjct: 1008 YLYMQQFAGLMMGVKYRIIGRRPA 1031 >PA1436 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1036 Score = 1016 bits (2626), Expect = 0.0, Method: Compositional matrix adjust. Identities = 520/1001 (51%), Positives = 715/1001 (71%), Gaps = 37/1001 (3%) Query: 34 VAPLPQVDFPTIQVSASLPGGSPETMASNVAQPLERQFSLIAGLSQMTSQSALGSTQITL 93 VAPLP+ DFPTIQ++A LPGGSPETMAS+VA PLE QFS I G+++MTS SALG+T +TL Sbjct: 38 VAPLPEADFPTIQINALLPGGSPETMASSVATPLEVQFSAIPGITEMTSSSALGTTTLTL 97 Query: 94 QFDLNRNIDAAALDVQAAINASTGQLPSNLPNPPTFRKVNPADSPIMIMSVQSDALPLTQ 153 QF L+++ID AA +VQAAINA+ G+LP ++PN PT+RKVNPADSPIMI+ V S+ +PL + Sbjct: 98 QFSLDKSIDVAAQEVQAAINAAAGRLPVDMPNLPTWRKVNPADSPIMILRVNSEMMPLIE 157 Query: 154 VSDFADNILAQQISQISGVGLVNVNGAQKPAVRIQVDPAKLATLNLSLEDIRGVIATTTV 213 +SD+A+ ILA+Q+SQ++GVG + V G Q+PA+RIQ P KLA L+L D+R + + +V Sbjct: 158 LSDYAETILARQLSQVNGVGQIFVVGQQRPAIRIQAQPEKLAAYQLTLADLRQSLQSASV 217 Query: 214 NQPKGTVDGTHQSFTVYTNDQLLSADPWNDMVLAYRAGAPIHVRDIGVAIDAPENMKIAA 273 N KG + G + T+ NDQL +A ++D+V+AYR GAP+ ++D+ + APE+ + A Sbjct: 218 NLAKGALYGEGRVSTLAANDQLFNASDYDDLVVAYRQGAPVFLKDVARIVSAPEDDYVQA 277 Query: 274 WAFSGAAAETDTTLTNG-RSIVLAITAMP--RLRAAIPXIKAAMPRLRAAIPASVHVNTL 330 W NG + L I P + I+AA+PRLR +PA++ V+ L Sbjct: 278 W-------------PNGVPGVALVILRQPGANIVDTADAIQAALPRLREMLPATIEVDVL 324 Query: 331 IDRTQTIRASVEDVEFTLVLTIALVVMVIFVFLRNIAATLIPSITVPLAIMGTAAVMYLV 390 DRT+TIR+S+ +VE TL+LTI LVV+V+ +FLR ++ATLI + + +++ + A MY++ Sbjct: 325 NDRTRTIRSSLHEVELTLLLTIGLVVLVMGLFLRQLSATLIVATVLAVSLSASFAAMYVL 384 Query: 391 GYSLDNLSLMALTIAVGFVVDDAIVMLENIYRYVEEGMSPMEAALKGSSEIGFTIISISV 450 G++L+NL+L+AL IAVGF+VDDAIV++ENI+R++E G S +EAALKG++EIGFT+ISIS Sbjct: 385 GFTLNNLTLVALIIAVGFIVDDAIVVVENIHRHLEAGASKVEAALKGAAEIGFTVISISF 444 Query: 451 SLVAVFIPLLLMGGIVGRLFREFAVTVTLTIGVSVIISLTLTPMLCSRF---LKNSHAEQ 507 SL+A FIPLL MGGIVGRLFREFAV+VT+ I +SV+ SLTL PML SRF L+++ A + Sbjct: 445 SLIAAFIPLLFMGGIVGRLFREFAVSVTVAILISVVASLTLAPMLASRFMPALRHAEAPR 504 Query: 508 HGKMYQLFERFFDALLNGYKRGLDLVLRHQFITLMSFLATVAVTVALFIFIPKGFFPQQD 567 G F + L GY+RGL L HQ + L+ F TV V VA ++ IPKGFFP QD Sbjct: 505 KG--------FAEWLTGGYERGLRWALGHQRLMLVGFAFTVLVAVAGYVGIPKGFFPLQD 556 Query: 568 NGVIAGFAESAQDISSSAMHRRLLQVADVVRKDPDVTGF----AMSAGSTTFNTGNFFIA 623 + G +++A+DIS M + Q+A+++ DP V + ++ GS + G F+I Sbjct: 557 TAFVFGTSQAAEDISYDDMVAKHRQLAEIIASDPAVQSYNHAVGVTGGSQSLANGRFWIV 616 Query: 624 LKPKSEGRTLDASEIITHLRPQVAKIQGVNLFMQASQDINVGGRLSRTQYQYTLTDSNLD 683 LK + E R + E I LRPQ+AK+ G+ L+++A+QDIN+ SRTQYQY L S+ Sbjct: 617 LKDRGE-RDVSVGEFIDRLRPQLAKVPGIMLYLRAAQDINLSSGPSRTQYQYALRSSDST 675 Query: 684 ELNVWAPKLVDRLRRLKQLTDVASDQQNSAATATITIDRARASSFGISPALIDATIYDAI 743 +L +WA +L +RL+++ L DV++D Q A+ + IDR A+ FG+S + T+YDA Sbjct: 676 QLALWAQRLTERLKQVPGLMDVSNDLQVGASVTALDIDRVAAARFGLSAEDVSQTLYDAF 735 Query: 744 GQRQVAQYFTQVNSYRVILEVTPELQKDPALFNKLYLTSPLTGQQVPLSTFIKVDTTKTA 803 GQRQV +Y T+VN Y+V+LE+ + + YL SPL+G+ VPLS KV ++ Sbjct: 736 GQRQVGEYQTEVNQYKVVLELDARQRGRAESLDWFYLRSPLSGEMVPLSAIAKVAAPRSG 795 Query: 804 YLSISHQSQFPAVTISFNLAHGVALGEAVDAINQAQAEMGVPTTLTGAFQGTAKAFGDSL 863 L I+H FPAV +SFNLA GV+LGEAV A+ +AQ E+G+P+T+ G FQG A+AF SL Sbjct: 796 PLQINHNGMFPAVNLSFNLAAGVSLGEAVQAVQRAQEEIGMPSTIIGVFQGAAQAFQSSL 855 Query: 864 SSQPYLIAAALIAVYIVLGLLYESYIHPLTILSTLPSAGVGALLILMAGGYDLSVIALIG 923 +SQP LI AALIAVYI+LG+LYES++HPLTILSTLPSAG+GA+ +L A G D S++ALIG Sbjct: 856 ASQPLLILAALIAVYIILGVLYESFVHPLTILSTLPSAGIGAVFLLWAWGQDFSIMALIG 915 Query: 924 I-----IXKKNGIMMIDFALTAERQHGMKPEEAIYQACLLRFRPIMMTTMCALLSGLPLM 978 I I KKNGI+M+DFA+ A+R+ GM E+AIYQACL RFRPIMMTT+ ALL +PLM Sbjct: 916 IVLLIGIVKKNGILMVDFAIVAQREQGMSAEQAIYQACLTRFRPIMMTTLAALLGAIPLM 975 Query: 979 LGHGAGSELRRPLGYAMVGGLVLSQALTLFTTPVVYLYLDR 1019 +G G GSELR+PLG A+VGGL++SQ LTLF+TPVVYL L+R Sbjct: 976 IGFGTGSELRQPLGIAVVGGLLVSQVLTLFSTPVVYLALER 1016 >PA2527 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1043 Score = 1015 bits (2624), Expect = 0.0, Method: Compositional matrix adjust. Identities = 541/1038 (52%), Positives = 719/1038 (69%), Gaps = 27/1038 (2%) Query: 4 SATFIKRPIGTTLLALAILLVGIAVWPLLPVAPLPQVDFPTIQVSASLPGGSPETMASNV 63 S FI RP+ TTLL +AILL G+ + LP++ LP+VD+PTIQV PG SPE M S++ Sbjct: 4 SRPFILRPVATTLLMVAILLSGLIAYRFLPISALPEVDYPTIQVVTLYPGASPEIMTSSI 63 Query: 64 AQPLERQFSLIAGLSQMTSQSALGSTQITLQFDLNRNIDAAALDVQAAINASTGQLPSNL 123 PLE Q I GL++M+S S+ G++ ITLQF L N+D A +VQAAINA+ LP++L Sbjct: 64 TAPLENQLGQIPGLNEMSSSSSGGASVITLQFSLQSNLDVAEQEVQAAINAAQSLLPNDL 123 Query: 124 PNPPTFRKVNPADSPIMIMSVQSDALPLTQVSDFADNILAQQISQISGVGLVNVNGAQKP 183 PN P F KVNPAD+PI+ ++V SD +PL Q+ D D LAQ+ISQISGVGLV+++G Q+P Sbjct: 124 PNQPVFSKVNPADAPILTLAVMSDGMPLPQIQDLVDTRLAQKISQISGVGLVSISGGQRP 183 Query: 184 AVRIQVDPAKLATLNLSLEDIRGVIATTTVNQPKGTVDGTHQSFTVYTNDQLLSADPWND 243 AVR++ +P LA LSLED+R + + +N PKG+ DG ++ T+ NDQL SAD + D Sbjct: 184 AVRVRANPTALAAAGLSLEDLRSTVTSNNLNGPKGSFDGPTRASTLDANDQLRSADAYRD 243 Query: 244 MVLAYRAGAPIHVRDIGVAIDAPENMKIAAWAFSGAAAETDTTLTNGRSIVLAITAMP-- 301 +++AY+ G+P+ +RD+ D EN+++AAWA N ++VL I P Sbjct: 244 LIIAYKNGSPLRIRDVASVEDDAENVRLAAWA------------NNLPAVVLNIQRQPGA 291 Query: 302 RLRAAIPXIKAAMPRLRAAIPASVHVNTLIDRTQTIRASVEDVEFTLVLTIALVVMVIFV 361 + + IKA +P+L++ +P ++ V L DRT TIRASV+DV+F L L +ALVVMV F+ Sbjct: 292 NVIEVVDRIKALLPQLQSTLPGNLDVQVLTDRTTTIRASVKDVQFELALAVALVVMVTFL 351 Query: 362 FLRNIAATLIPSITVPLAIMGTAAVMYLVGYSLDNLSLMALTIAVGFVVDDAIVMLENIY 421 FLRN+ ATLIPS VPL+++GT VMYL G+S++NL+LMALTIA GFVVDDAIVM+ENI Sbjct: 352 FLRNVYATLIPSFAVPLSLIGTFGVMYLSGFSINNLTLMALTIATGFVVDDAIVMVENIA 411 Query: 422 RYVEEGMSPMEAALKGSSEIGFTIISISVSLVAVFIPLLLMGGIVGRLFREFAVTVTLTI 481 RY+E+G SP+EAALKGS +IGFTIIS++ SL+AV IPLL MG + GRLFREFA+T+ + I Sbjct: 412 RYLEQGDSPLEAALKGSKQIGFTIISLTFSLIAVLIPLLFMGDVAGRLFREFAITLAVAI 471 Query: 482 GVSVIISLTLTPMLCSRFLKNSHAEQHGKMYQLFERFFDALLNGYKRGLDLVLRHQFITL 541 +S +SLTLTPML ++ L++ +Q G+ + R D L+ Y + L +VLRHQ +TL Sbjct: 472 LISGFVSLTLTPMLSAKLLRHIDEDQQGRFARAAGRVIDGLIAQYAKALRVVLRHQPLTL 531 Query: 542 MSFLATVAVTVALFIFIPKGFFPQQDNGVIAGFAESAQDISSSAMHRRLLQVADVVRKDP 601 + +AT+A+T L++ +PKGFFP QD GVI G AE+ Q IS AM R +A+VV KDP Sbjct: 532 LVAIATLALTALLYLAMPKGFFPVQDTGVIQGVAEAPQSISFQAMSERQRALAEVVLKDP 591 Query: 602 DVTGFAMSAG----STTFNTGNFFIALKPKSEGRTLDASEIITHLRPQVAKIQGVNLFMQ 657 V + G + T NTG I LKP SE R + ASE+I L+P++ + G+ L+MQ Sbjct: 592 AVASLSSYIGVDGSNPTLNTGRLLINLKPHSE-RDVTASEVIQRLQPELDHLPGIKLYMQ 650 Query: 658 ASQDINVGGRLSRTQYQYTLTDSNLDELNVWAPKLVDRLRRLKQLTDVASDQQNSAATAT 717 QD+ + R++RTQYQ+TL D++ D L W PKLV RL+ L QL DVASD Q+ A Sbjct: 651 PVQDLTIEDRVARTQYQFTLQDADPDVLAEWVPKLVARLQELPQLADVASDWQDKGLQAY 710 Query: 718 ITIDRARASSFGISPALIDATIYDAIGQRQVAQYFTQVNSYRVILEVTPELQKDPALFNK 777 + IDR AS G+ + ID+ +Y+A GQR ++ FTQ YRV+LEV P+ Q P + Sbjct: 711 LNIDRDTASRLGVKLSDIDSVLYNAFGQRLISTIFTQATQYRVVLEVAPQFQLGPQALEQ 770 Query: 778 LYLTSPLTGQQVPLSTFIKVDTTKTAYLSISHQSQFPAVTISFNLAHGVALGEAVDAINQ 837 LY+ S G QV LS+ KV+ T L+I+H +QFP+ T+SFNLA G +LGEAV+AI Sbjct: 771 LYVPSS-DGTQVRLSSLAKVEERHT-LLAINHIAQFPSATLSFNLAKGYSLGEAVEAIRG 828 Query: 838 AQAEMGVPTTLTGAFQGTAKAFGDSLSSQPYLIAAALIAVYIVLGLLYESYIHPLTILST 897 +A + +P ++ G+F+G A AF SLS+ LI A+++ +YIVLG+LYES+IHP+TILST Sbjct: 829 VEASLELPLSMQGSFRGAALAFEASLSNTLLLILASVVTMYIVLGILYESFIHPVTILST 888 Query: 898 LPSAGVGALLILMAGGYD-----LSVIALIGIIXKKNGIMMIDFALTAERQHGMKPEEAI 952 LPSAGVGALL LM G + + I L+ I KKN IMMIDFAL AER G P EAI Sbjct: 889 LPSAGVGALLALMLAGQEIGIVAIIGIILLIGIVKKNAIMMIDFALDAERNEGKPPHEAI 948 Query: 953 YQACLLRFRPIMMTTMCALLSGLPLMLGHGAGSELRRPLGYAMVGGLVLSQALTLFTTPV 1012 YQACLLRFRPI+MTTM ALL LPLML GAG+ELR+PLG MVGGL+LSQ LTLFTTPV Sbjct: 949 YQACLLRFRPILMTTMAALLGALPLMLAGGAGAELRQPLGITMVGGLLLSQVLTLFTTPV 1008 Query: 1013 VYLYLDR-AHYWYMNKKE 1029 +YLY DR A W +K+ Sbjct: 1009 IYLYFDRLARRWAAWRKQ 1026