BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0292.p (337 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1187 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Rso... 453 e-127 PAB0090 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Pab... 197 3e-50 Rv2913c [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Mtu... 103 4e-22 MT2981 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase MtC ... 103 4e-22 CC3460 Non COG 78 4e-14 >RSp1187 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Rso Ralstonia solanacearum Length = 494 Score = 453 bits (1165), Expect = e-127, Method: Compositional matrix adjust. Identities = 225/324 (69%), Positives = 266/324 (82%), Gaps = 6/324 (1%) Query: 17 DTLIRNVFLVDGSGNDP--VVADVAIAGGRIAAIGALGD---WQAQQVMDGTGKVLSPGF 71 D++IR V +VDGSG++P + DVAIA GRIAAI A D W + +DG G+VL+PGF Sbjct: 5 DSVIRRVRIVDGSGHEPESTLFDVAIADGRIAAI-ATSDSTAWLGDEEVDGAGRVLAPGF 63 Query: 72 IDVHTHDDTNVIRMPDMFPKLSQGVTTVVVGNCGISASPVTLKGDPPDPMNLLGQSTAFS 131 IDVHTHDDTNVIR PDM PK+SQG+TTV+VGNCGISASP TL+G+PPDPMNLLG + AF Sbjct: 64 IDVHTHDDTNVIRTPDMLPKVSQGITTVIVGNCGISASPATLRGEPPDPMNLLGPAGAFR 123 Query: 132 YPTFASYVAAIGAARPSVNVAALVGHTALRSNHMDRLDRAASDAEIVGMREQLTEALEHG 191 YPTFASYV A+ ARP+VNVAALVGHTALR+NH+DRLDR A+ E+ MR QL EAL+HG Sbjct: 124 YPTFASYVEAVEQARPAVNVAALVGHTALRNNHLDRLDRPATAPEVEAMRAQLREALDHG 183 Query: 192 ALGLSTGLAYGNAINAPTGEVLALAEPLAEYGAMYATHLRSEFADILVAMDEAFRIGKHA 251 ALGLSTGLAY NA A T EV++LAEPLAE GA+Y THLR+EFA IL AMDEA+R+G+HA Sbjct: 184 ALGLSTGLAYANAHAAATEEVMSLAEPLAEAGALYTTHLRTEFAAILEAMDEAYRVGRHA 243 Query: 252 RVPVVISHLKCAGVENWGRSSEVLAALEQAEKHQHVGCDCYPYTASSSTLDLKQVTDTYP 311 RVP+VISHLKCAG NWGR+ EVL ++E A+++Q VGCDCYPYTASSSTLDLKQVTD + Sbjct: 244 RVPIVISHLKCAGAANWGRAGEVLESIEAAQRYQPVGCDCYPYTASSSTLDLKQVTDEFD 303 Query: 312 IQVTWSEPHPEQGGKLLSEIAAGW 335 I +TWS+PHPE G+ L IAA W Sbjct: 304 IVITWSDPHPEMAGQTLKAIAAAW 327 >PAB0090 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Pab Pyrococcus abyssi Length = 526 Score = 197 bits (501), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 111/291 (38%), Positives = 170/291 (58%), Gaps = 9/291 (3%) Query: 17 DTLIRNVFLVDGSGNDPVVADVAIAGGRIAAIGALGDWQAQQVMDGTGKVLSPGFIDVHT 76 D +I+N +VDG+GN D+ I G+I IG + + Q +D + +++PGFID+H Sbjct: 5 DIVIKNGKIVDGTGNPWFRTDIGIKDGKIVKIGKIKE-DGQVTIDASNLIVAPGFIDMHA 63 Query: 77 HDDTNVIRMPDMF--PKLSQGVTTVVVGNCGISASPVT--LKGDPPDPMNLLGQSTAFSY 132 HDD +I D F KL QGVTTVV GNCGIS +PV + + +LG+ F + Sbjct: 64 HDD--LIFFKDRFNRAKLLQGVTTVVSGNCGISVAPVNEEMLDVLKSYVGILGKEVEFKW 121 Query: 133 PTFASYVAAIGAARP-SVNVAALVGHTALRSNHMDRLDRAASDAEIVGMREQLTEALEHG 191 ++ ++ A+ P N LVGH LR M R ++ E+ M+E L +++E G Sbjct: 122 RSYGEFLDALEEVGPLGTNFVGLVGHGTLRIAVMGMEARDPTEEELGRMKELLAKSMEEG 181 Query: 192 ALGLSTGLAYGNAINAPTGEVLALAEPLAEYGAMYATHLRSEFADILVAMDEAFRIGKHA 251 A G+S+GL Y + + T E++ LA +A+YG +Y+TH+R E ++ A++EA RIG+ + Sbjct: 182 AFGMSSGLIYPPGVYSKTWELIELAMVVAKYGGIYSTHMRDEGNRVIEALEEAIRIGRES 241 Query: 252 RVPVVISHLKCAGVENWGRSSEVLAALEQAEKHQ-HVGCDCYPYTASSSTL 301 V V +SH K +G +NWG+S + LA +E+A + D YPYTA S+ L Sbjct: 242 GVRVEVSHHKVSGRKNWGKSRKTLALIEKARNEGIEITLDVYPYTAGSTYL 292 >Rv2913c [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Mtu Mycobacterium tuberculosis H37Rv Length = 611 Score = 103 bits (258), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 73/203 (35%), Positives = 107/203 (52%), Gaps = 26/203 (12%) Query: 15 SCDTLIRNVFLVDGSGNDPVVADVAIAGGRIAAI--GALGDWQAQQVMDGTGKVLSPGFI 72 + D +IR+ DG+GN P+ + I G +A + GAL + +V+D GK + PGFI Sbjct: 15 TYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAAGALDETGCPEVVDAAGKWVVPGFI 74 Query: 73 DVHTHDDTNVIRMPDMFPKLSQGVTTVVVGNCGISASPVTLKGDPPDPMNLLGQSTAF-- 130 DVHTH D V+ P + + GVTTV++GNC +S T+ + D +L + A Sbjct: 75 DVHTHYDAEVLLDPGLRESVRHGVTTVLLGNCSLS----TVYANSEDAADLFSRVEAVPR 130 Query: 131 -----------SYPTFASYVAAIGAARPSVNVAALVGHTALRSNHMDRLDRAASD----- 174 ++ T A Y+ AI A NV++L+GH+ LR+ + LDRA D Sbjct: 131 EFVLGALRDNQTWSTPAEYIEAIDALPLGPNVSSLLGHSDLRTAVLG-LDRATDDTVRPT 189 Query: 175 -AEIVGMREQLTEALEHGALGLS 196 AE+ M + L EALE G LG+S Sbjct: 190 EAELAKMAKLLDEALEAGMLGMS 212 >MT2981 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase MtC Mycobacterium tuberculosis CDC1551 Length = 611 Score = 103 bits (258), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 73/203 (35%), Positives = 107/203 (52%), Gaps = 26/203 (12%) Query: 15 SCDTLIRNVFLVDGSGNDPVVADVAIAGGRIAAI--GALGDWQAQQVMDGTGKVLSPGFI 72 + D +IR+ DG+GN P+ + I G +A + GAL + +V+D GK + PGFI Sbjct: 15 TYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAAGALDETGCPEVVDAAGKWVVPGFI 74 Query: 73 DVHTHDDTNVIRMPDMFPKLSQGVTTVVVGNCGISASPVTLKGDPPDPMNLLGQSTAF-- 130 DVHTH D V+ P + + GVTTV++GNC +S T+ + D +L + A Sbjct: 75 DVHTHYDAEVLLDPGLRESVRHGVTTVLLGNCSLS----TVYANSEDAADLFSRVEAVPR 130 Query: 131 -----------SYPTFASYVAAIGAARPSVNVAALVGHTALRSNHMDRLDRAASD----- 174 ++ T A Y+ AI A NV++L+GH+ LR+ + LDRA D Sbjct: 131 EFVLGALRDNQTWSTPAEYIEAIDALPLGPNVSSLLGHSDLRTAVLG-LDRATDDTVRPT 189 Query: 175 -AEIVGMREQLTEALEHGALGLS 196 AE+ M + L EALE G LG+S Sbjct: 190 EAELAKMAKLLDEALEAGMLGMS 212 >CC3460 Non COG Length = 581 Score = 77.8 bits (190), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 63/200 (31%), Positives = 96/200 (48%), Gaps = 20/200 (10%) Query: 14 HSCDTLIRNVFLVDGSGNDPVVADVAIAGGRIAAIGALGDWQAQQVMDGTGKVLSPGFID 73 + D ++R+ + DG+G ADV + G I A+G G + +D G++++PGF+D Sbjct: 4 RAYDLVLRSGVVFDGAGGPGFQADVGVRDGVIVAVGK-GLAAGAEEIDARGRIVTPGFVD 62 Query: 74 VHTHDDTNVIRMPDMFPKLSQGVTTVVVGNCGISASPVT----------LKGDPPDPMNL 123 +HTH D + P GVTTVV+GNCG+ +P ++G P + Sbjct: 63 IHTHYDGQATWSGQLGPSSGHGVTTVVMGNCGVGFAPCRPDDHDRLIRLMEGVEDIPFPV 122 Query: 124 LGQSTAFSYPTFASYVAAIGAARPSVNVAALVGHTALRSNHMDRLDRAASDAE------I 177 L + +++ +F Y+ + V+V A + H ALR M DR A D E I Sbjct: 123 LTEGLPWAWESFPDYLDFLAGRAFDVDVGAQLPHAALRVYVMG--DRGA-DREPATDADI 179 Query: 178 VGMREQLTEALEHGALGLST 197 M A+E GALG ST Sbjct: 180 AAMAAIARRAVEAGALGFST 199