BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0272.p (237 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMB1483 [M] COG0739 Membrane proteins related to metalloendopept... 155 8e-38 PM1614 [M] COG0739 Membrane proteins related to metalloendopepti... 154 2e-37 NMA1692 [M] COG0739 Membrane proteins related to metalloendopept... 152 5e-37 STM3038 [M] COG0739 Membrane proteins related to metalloendopept... 150 2e-36 ygeR [M] COG0739 Membrane proteins related to metalloendopeptida... 150 2e-36 >NMB1483 [M] COG0739 Membrane proteins related to metalloendopeptidases Nme Neisseria meningitidis MC58 Length = 415 Score = 155 bits (392), Expect = 8e-38, Method: Compositional matrix adjust. Identities = 87/235 (37%), Positives = 125/235 (53%), Gaps = 44/235 (18%) Query: 29 SYTVRKGDTLMSISRTVGKDHHDIAAWNKLSDANEIYPGDVLRLKPPATAAVAAPVSRAK 88 ++T+ +GDT+ +IS+ D AWN ++D N + G ++++KP A AAP + Sbjct: 184 THTIVRGDTVYNISKRYHISQDDFRAWNGMTD-NMLSIGQIVKVKP---AGYAAPKT--- 236 Query: 89 PAAAVHERKAEPKTEREAAAPAATEAER-------------------------------- 116 AAV R A P + PAA + Sbjct: 237 --AAVESRPAVPAAVQTPVKPAAQPPVQSAPQPAAPAAENKAVPAPAPQSPAASPSGTRS 294 Query: 117 ---LDWMWPAQGKLTATTDRNLKGIDITGTPGQPVWAAEAGKVTYAGRGIRGYGNMIIVK 173 + W P QGK+ A N KG+DI G GQPV AA GKV YAG G+RGYGN++I++ Sbjct: 295 VGGIVWQRPTQGKVVADFGGNNKGVDIAGNAGQPVLAAADGKVVYAGSGLRGYGNLVIIQ 354 Query: 174 HSRTLLSVYAHNKSIMVKEGQTVNRGQQIAEMGDTDSRTVKLYFEIRSNGKALNP 228 H+ + L+ Y HN+ ++V EGQ V RGQQ+A MG+TD+ +L+FE+R NGK +NP Sbjct: 355 HNSSFLTAYGHNQKLLVGEGQQVKRGQQVALMGNTDASRTQLHFEVRQNGKPVNP 409 >PM1614 [M] COG0739 Membrane proteins related to metalloendopeptidases Pmu Pasteurella multocida Length = 467 Score = 154 bits (388), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 92/257 (35%), Positives = 134/257 (52%), Gaps = 47/257 (18%) Query: 25 YQGDSYTVRKGDTLMSISRTVGKDHHDIAAWNKLSDANEIYPGDVLRLK---------PP 75 Y+G++YTVRKGDT+ I+ G D ++A+ N +S+ + G LR+ P Sbjct: 210 YKGETYTVRKGDTMYLIAYISGLDVKELASLNNMSEPYRLSVGQTLRVSNGRVASTSSQP 269 Query: 76 ATAAVAAPVSRAKPAAAVH------------------------------ERKAEPKTERE 105 T V PVS+ K + + + + K Sbjct: 270 VTQPVTVPVSQPKSSEVTYTPGPHGTQYGSDGTIIGPIKSGVSSAPVPVQPEPVVKPVES 329 Query: 106 AAAPAATEAER-----LDWMWPAQGKLT---ATTDRNLKGIDITGTPGQPVWAAEAGKVT 157 + P + + + + W WP +G + +T D KGIDI G+ GQ V AA AG+V Sbjct: 330 TSVPVPSTSSKHMVSNVTWQWPTKGNIVQGFSTADGGNKGIDIAGSRGQAVNAAAAGRVV 389 Query: 158 YAGRGIRGYGNMIIVKHSRTLLSVYAHNKSIMVKEGQTVNRGQQIAEMGDTDSRTVKLYF 217 YAG +RGYGN+II+KH+ LS YAHN+SI+VK+ Q V GQQIA+MG + + +VKL+F Sbjct: 390 YAGNALRGYGNLIIIKHNDDYLSAYAHNESILVKDQQEVRAGQQIAKMGSSGTNSVKLHF 449 Query: 218 EIRSNGKALNPVPLLPK 234 EIR GK+++P LPK Sbjct: 450 EIRYKGKSVDPTRYLPK 466 >NMA1692 [M] COG0739 Membrane proteins related to metalloendopeptidases NmA Neisseria meningitidis Z2491 Length = 415 Score = 152 bits (385), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 91/247 (36%), Positives = 135/247 (54%), Gaps = 30/247 (12%) Query: 11 AVVVAALTACASAPYQGD--SYTVRKGDTLMSISRTVGKDHHDIAAWNKLSDANEIYPGD 68 AV AA SAP + ++T+ +GDT+ +IS+ D AWN ++D N + G Sbjct: 164 AVPAAAQPLVQSAPVDINAATHTIVRGDTVYNISKRYHISQDDFRAWNGMTD-NTLSIGQ 222 Query: 69 VLRLKPPATAAVAAPVSRAKPA--AAVH---ERKAEPKTEREAAAPAATEAER------- 116 ++++KP AA A +++PA AAV + A+P + A + Sbjct: 223 IVKVKPAGYAAPKAAAVKSRPAVPAAVQTPVKPAAQPPVQSAPQPAAPAAENKAVPAPAP 282 Query: 117 ---------------LDWMWPAQGKLTATTDRNLKGIDITGTPGQPVWAAEAGKVTYAGR 161 + W P QGK+ A N KG+DI G GQPV AA GKV YAG Sbjct: 283 QSPAASPSGTRSVGGIVWQRPTQGKVVADFGGNNKGVDIAGNAGQPVLAAADGKVVYAGS 342 Query: 162 GIRGYGNMIIVKHSRTLLSVYAHNKSIMVKEGQTVNRGQQIAEMGDTDSRTVKLYFEIRS 221 G+RGYGN++I++H+ + L+ Y HN+ ++V EGQ V RGQQ+A MG+T++ +L+FE+R Sbjct: 343 GLRGYGNLVIIQHNSSFLTAYGHNQKLLVGEGQQVKRGQQVALMGNTEASRTQLHFEVRQ 402 Query: 222 NGKALNP 228 NGK +NP Sbjct: 403 NGKPVNP 409 >STM3038 [M] COG0739 Membrane proteins related to metalloendopeptidases Sty Salmonella typhimurium LT2 Length = 252 Score = 150 bits (380), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 86/234 (36%), Positives = 133/234 (56%), Gaps = 14/234 (5%) Query: 7 IVAAAVVVAALTA-CASAPYQGDSYTVRKGDTLMSISRTVGKDHHDIAAWNKLSDANEIY 65 ++ +++A ++ S Y G YTV++GDTL ISR G ++A N +S I Sbjct: 18 LLCTGLLLAGCSSNSGSGTYSGSVYTVKRGDTLYRISRATGTSVKELARLNGISPPYTIE 77 Query: 66 PGDVLRLKPPATAAVAAPVSRAKPA---AAVHERKAEPKTEREAAAPAATEAERLDWMWP 122 G ++++ A ++ + + K A AAV + PK+ P W+WP Sbjct: 78 VGQRIKVRGSAKSSTSTRKTSNKTATKTAAVRPSSSVPKSSWP---PVGQRC----WVWP 130 Query: 123 AQGKLT---ATTDRNLKGIDITGTPGQPVWAAEAGKVTYAGRGIRGYGNMIIVKHSRTLL 179 A GK+ +T + KGIDI G G PV+AA AGKV Y G +RGYGN+I++KH+ + Sbjct: 131 ANGKVILPYSTAEGGNKGIDIAGARGTPVYAAGAGKVVYVGNQLRGYGNLIMIKHNEDYI 190 Query: 180 SVYAHNKSIMVKEGQTVNRGQQIAEMGDTDSRTVKLYFEIRSNGKALNPVPLLP 233 + YAHN +++V GQ+V GQ+IA MG TD+ +V+L+F+IR A++P+ LP Sbjct: 191 TAYAHNDTMLVNNGQSVKAGQKIATMGSTDAASVRLHFQIRYRATAIDPLRYLP 244 >ygeR [M] COG0739 Membrane proteins related to metalloendopeptidases Eco Escherichia coli K12 Length = 259 Score = 150 bits (379), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 86/240 (35%), Positives = 134/240 (55%), Gaps = 15/240 (6%) Query: 2 LRYISIVAAAVVVAALTACASA---PYQGDSYTVRKGDTLMSISRTVGKDHHDIAAWNKL 58 L + +++ +++A + S+ Y G YTV++GDTL ISRT G ++A N + Sbjct: 19 LGIVMLLSVGLLLAGCSGSKSSDTGTYSGSVYTVKRGDTLYRISRTTGTSVKELARLNGI 78 Query: 59 SDANEIYPGDVLRLKPPATAAVA--APVSRAKPAAAVHERKAEPKTEREAAAPAATEAER 116 S I G L+L ++++ + A+V A PK+ + P Sbjct: 79 SPPYTIEVGQKLKLGGAKSSSITRKSTAKSTTKTASVTPSSAVPKS---SWPPVGQRC-- 133 Query: 117 LDWMWPAQGKLT---ATTDRNLKGIDITGTPGQPVWAAEAGKVTYAGRGIRGYGNMIIVK 173 W+WP GK+ +T D KGIDI+ G P++AA AGKV Y G +RGYGN+I++K Sbjct: 134 --WLWPTTGKVIMPYSTADGGNKGIDISAPRGTPIYAAGAGKVVYVGNQLRGYGNLIMIK 191 Query: 174 HSRTLLSVYAHNKSIMVKEGQTVNRGQQIAEMGDTDSRTVKLYFEIRSNGKALNPVPLLP 233 HS ++ YAHN +++V GQ+V GQ+IA MG TD+ +V+L+F+IR A++P+ LP Sbjct: 192 HSEDYITAYAHNDTMLVNNGQSVKAGQKIATMGSTDAASVRLHFQIRYRATAIDPLRYLP 251