BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0226.p (514 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mgtA [P] COG0474 Cation transport ATPase Eco Escherichia coli K12 519 e-147 ECs5219 [P] COG0474 Cation transport ATPase Ecs Escherichia coli... 519 e-147 ZmgtA [P] COG0474 Cation transport ATPase EcZ Escherichia coli O... 518 e-147 STM4456 [P] COG0474 Cation transport ATPase Sty Salmonella typhi... 505 e-143 BMEII0056 [P] COG0474 Cation transport ATPase Bme Brucella melit... 505 e-142 >mgtA [P] COG0474 Cation transport ATPase Eco Escherichia coli K12 Length = 898 Score = 519 bits (1336), Expect = e-147, Method: Compositional matrix adjust. Identities = 260/514 (50%), Positives = 348/514 (67%), Gaps = 13/514 (2%) Query: 3 SQKVTRYAYLNSFFQTGLKNLLDMAILNYVDPGKKSATPAETKAETEKEFRKIDELPFDF 62 S++V A+LNS +QTGLKNLLD A+L D E+ ++KIDE+PFDF Sbjct: 396 SERVLHSAWLNSHYQTGLKNLLDTAVLEGTD--------EESARSLASRWQKIDEIPFDF 447 Query: 63 ERRRMSVIVEQADRTRLLICKGAPEEILAVCTHAEHAGAPMPLAGHHGAALSKTVDDLNE 122 ERRRMSV+V + L+CKGA +EIL VC+ H G +PL + + D LN Sbjct: 448 ERRRMSVVVAENTEHHQLVCKGALQEILNVCSQVRHNGEIVPLDDIMLRKIKRVTDTLNR 507 Query: 123 DGFRVIAVAYKELPAATAEVPALGNADESALTLVGYIAFLDPPKDSAGEAIAGLHACGVT 182 G RV+AVA K LPA + ADES L L GYIAFLDPPK++ A+ L A G+T Sbjct: 508 QGLRVVAVATKYLPAREGD---YQRADESDLILEGYIAFLDPPKETTAPALKALKASGIT 564 Query: 183 VKVLSGDNGAVVRNVCRHVGLSGEQAVLGSDIDTLSDEALGELAEHSNIFAKLNPQQKAR 242 VK+L+GD+ V VC VGL + V+GSDI+TLSD+ L LA+ + +FA+L P K R Sbjct: 565 VKILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKER 624 Query: 243 IIRCLQARRHVVGYLGDGINDGAALKAADVGISVDSAVDIAKESADIILMRKSLIVLKDG 302 I+ L+ HVVG++GDGIND AL+AAD+GISVD AVDIA+E+ADIIL+ KSL+VL++G Sbjct: 625 IVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLEEG 684 Query: 303 VLEGRRVFGNITKYIKMSSSSAFGNMLSVLGASAMLPFLPMAPVQILLNNLLYDFSQTTI 362 V+EGRR F N+ KYIKM++SS FGN+ SVL ASA LPFLPM P+ +L+ NLLYD SQ I Sbjct: 685 VIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLLYDVSQVAI 744 Query: 363 ATDHVDAEYLKQPRRWEILDIGRFMMVLGPVSSLFDYMTFGVLWYFFGA--AGQPLLFQS 420 D+VD E +++P+RW D+GRFM+ GP+SS+FD +TF ++W+ F A LFQS Sbjct: 745 PFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPETQTLFQS 804 Query: 421 GWFVESLLSQTLVVHVIRTGKIPFVQSKPSLPLLATTAVICVLAFWLPASSIAHTLGLTA 480 GWFV LLSQTL+VH+IRT ++PF+QS S PL+ T ++ ++ LP S +A L L A Sbjct: 805 GWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPLASYLQLQA 864 Query: 481 LPLNLNAAILAIVFAYLLMTQLMKSWLIRRFGLK 514 LPL+ ++AI+ Y+ +TQL+K + RR+G + Sbjct: 865 LPLSYFPWLVAILAGYMTLTQLVKGFYSRRYGWQ 898 >ECs5219 [P] COG0474 Cation transport ATPase Ecs Escherichia coli O157:H7 Length = 898 Score = 519 bits (1336), Expect = e-147, Method: Compositional matrix adjust. Identities = 260/514 (50%), Positives = 348/514 (67%), Gaps = 13/514 (2%) Query: 3 SQKVTRYAYLNSFFQTGLKNLLDMAILNYVDPGKKSATPAETKAETEKEFRKIDELPFDF 62 S++V A+LNS +QTGLKNLLD A+L D E+ ++KIDE+PFDF Sbjct: 396 SERVLHSAWLNSHYQTGLKNLLDTAVLEGTD--------EESARSLASRWQKIDEIPFDF 447 Query: 63 ERRRMSVIVEQADRTRLLICKGAPEEILAVCTHAEHAGAPMPLAGHHGAALSKTVDDLNE 122 ERRRMSV+V + L+CKGA +EIL VC+ H G +PL + + D LN Sbjct: 448 ERRRMSVVVAENTEHHQLVCKGALQEILNVCSQVRHNGEIVPLDDIMLRKIKRVTDTLNR 507 Query: 123 DGFRVIAVAYKELPAATAEVPALGNADESALTLVGYIAFLDPPKDSAGEAIAGLHACGVT 182 G RV+AVA K LPA + ADES L L GYIAFLDPPK++ A+ L A G+T Sbjct: 508 QGLRVVAVATKYLPAREGD---YQRADESDLILEGYIAFLDPPKETTAPALKALKASGIT 564 Query: 183 VKVLSGDNGAVVRNVCRHVGLSGEQAVLGSDIDTLSDEALGELAEHSNIFAKLNPQQKAR 242 VK+L+GD+ V VC VGL + V+GSDI+TLSD+ L LA+ + +FA+L P K R Sbjct: 565 VKILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKER 624 Query: 243 IIRCLQARRHVVGYLGDGINDGAALKAADVGISVDSAVDIAKESADIILMRKSLIVLKDG 302 I+ L+ HVVG++GDGIND AL+AAD+GISVD AVDIA+E+ADIIL+ KSL+VL++G Sbjct: 625 IVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLEEG 684 Query: 303 VLEGRRVFGNITKYIKMSSSSAFGNMLSVLGASAMLPFLPMAPVQILLNNLLYDFSQTTI 362 V+EGRR F N+ KYIKM++SS FGN+ SVL ASA LPFLPM P+ +L+ NLLYD SQ I Sbjct: 685 VIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLLYDVSQVAI 744 Query: 363 ATDHVDAEYLKQPRRWEILDIGRFMMVLGPVSSLFDYMTFGVLWYFFGA--AGQPLLFQS 420 D+VD E +++P+RW D+GRFM+ GP+SS+FD +TF ++W+ F A LFQS Sbjct: 745 PFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPETQTLFQS 804 Query: 421 GWFVESLLSQTLVVHVIRTGKIPFVQSKPSLPLLATTAVICVLAFWLPASSIAHTLGLTA 480 GWFV LLSQTL+VH+IRT ++PF+QS S PL+ T ++ ++ LP S +A L L A Sbjct: 805 GWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPLASYLQLQA 864 Query: 481 LPLNLNAAILAIVFAYLLMTQLMKSWLIRRFGLK 514 LPL+ ++AI+ Y+ +TQL+K + RR+G + Sbjct: 865 LPLSYFPWLVAILAGYMTLTQLVKGFYSRRYGWQ 898 >ZmgtA [P] COG0474 Cation transport ATPase EcZ Escherichia coli O157:H7 EDL933 Length = 898 Score = 518 bits (1335), Expect = e-147, Method: Compositional matrix adjust. Identities = 260/514 (50%), Positives = 348/514 (67%), Gaps = 13/514 (2%) Query: 3 SQKVTRYAYLNSFFQTGLKNLLDMAILNYVDPGKKSATPAETKAETEKEFRKIDELPFDF 62 S++V A+LNS +QTGLKNLLD A+L D E+ ++KIDE+PFDF Sbjct: 396 SERVLHSAWLNSHYQTGLKNLLDTAVLEGTD--------EESARSLASRWQKIDEIPFDF 447 Query: 63 ERRRMSVIVEQADRTRLLICKGAPEEILAVCTHAEHAGAPMPLAGHHGAALSKTVDDLNE 122 ERRRMSV+V + L+CKGA +EIL VC+ H G +PL + + D LN Sbjct: 448 ERRRMSVVVAENTEHHQLVCKGALQEILNVCSQVRHNGEIVPLDDIMLRKIKRVTDTLNR 507 Query: 123 DGFRVIAVAYKELPAATAEVPALGNADESALTLVGYIAFLDPPKDSAGEAIAGLHACGVT 182 G RV+AVA K LPA + ADES L L GYIAFLDPPK++ A+ L A G+T Sbjct: 508 QGLRVVAVATKYLPAREGD---YQRADESDLILEGYIAFLDPPKETTXPALKALKASGIT 564 Query: 183 VKVLSGDNGAVVRNVCRHVGLSGEQAVLGSDIDTLSDEALGELAEHSNIFAKLNPQQKAR 242 VK+L+GD+ V VC VGL + V+GSDI+TLSD+ L LA+ + +FA+L P K R Sbjct: 565 VKILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKER 624 Query: 243 IIRCLQARRHVVGYLGDGINDGAALKAADVGISVDSAVDIAKESADIILMRKSLIVLKDG 302 I+ L+ HVVG++GDGIND AL+AAD+GISVD AVDIA+E+ADIIL+ KSL+VL++G Sbjct: 625 IVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLEEG 684 Query: 303 VLEGRRVFGNITKYIKMSSSSAFGNMLSVLGASAMLPFLPMAPVQILLNNLLYDFSQTTI 362 V+EGRR F N+ KYIKM++SS FGN+ SVL ASA LPFLPM P+ +L+ NLLYD SQ I Sbjct: 685 VIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLLYDVSQVAI 744 Query: 363 ATDHVDAEYLKQPRRWEILDIGRFMMVLGPVSSLFDYMTFGVLWYFFGA--AGQPLLFQS 420 D+VD E +++P+RW D+GRFM+ GP+SS+FD +TF ++W+ F A LFQS Sbjct: 745 PFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPETQTLFQS 804 Query: 421 GWFVESLLSQTLVVHVIRTGKIPFVQSKPSLPLLATTAVICVLAFWLPASSIAHTLGLTA 480 GWFV LLSQTL+VH+IRT ++PF+QS S PL+ T ++ ++ LP S +A L L A Sbjct: 805 GWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPLASYLQLQA 864 Query: 481 LPLNLNAAILAIVFAYLLMTQLMKSWLIRRFGLK 514 LPL+ ++AI+ Y+ +TQL+K + RR+G + Sbjct: 865 LPLSYFPWLVAILAGYMTLTQLVKGFYSRRYGWQ 898 >STM4456 [P] COG0474 Cation transport ATPase Sty Salmonella typhimurium LT2 Length = 902 Score = 505 bits (1301), Expect = e-143, Method: Compositional matrix adjust. Identities = 263/515 (51%), Positives = 351/515 (68%), Gaps = 15/515 (2%) Query: 3 SQKVTRYAYLNSFFQTGLKNLLDMAILNYVDPGKKSATPAETKA-ETEKEFRKIDELPFD 61 S+ V A+LNS +QTGLKNLLD A+L VD ET A + ++KIDE+PFD Sbjct: 400 SEHVLHCAWLNSHYQTGLKNLLDTAVLEGVD---------ETAARQLSGRWQKIDEIPFD 450 Query: 62 FERRRMSVIVEQADRTRLLICKGAPEEILAVCTHAEHAGAPMPLAGHHGAALSKTVDDLN 121 FERRRMSV+V + L+CKGA +EIL VCT H G +PL + + + D LN Sbjct: 451 FERRRMSVVVAEDSNVHQLVCKGALQEILNVCTQVRHNGDIVPLDDNMLRRVKRVTDTLN 510 Query: 122 EDGFRVIAVAYKELPAATAEVPALGNADESALTLVGYIAFLDPPKDSAGEAIAGLHACGV 181 G RV+AVA K LPA + + DES L L GYIAFLDPPK++ A+ L A G+ Sbjct: 511 RQGLRVVAVATKYLPAREGDYQRI---DESDLILEGYIAFLDPPKETTAPALKALKASGI 567 Query: 182 TVKVLSGDNGAVVRNVCRHVGLSGEQAVLGSDIDTLSDEALGELAEHSNIFAKLNPQQKA 241 TVK+L+GD+ V VC VGL ++GSDI+ LSD+AL LA + +FA+L P K Sbjct: 568 TVKILTGDSELVAAKVCHEVGLDAGDVIIGSDIEGLSDDALAALAARTTLFARLTPMHKE 627 Query: 242 RIIRCLQARRHVVGYLGDGINDGAALKAADVGISVDSAVDIAKESADIILMRKSLIVLKD 301 RI+ L+ HVVG++GDGIND AL+AAD+GISVD AVDIA+E+ADIIL+ KSL+VL++ Sbjct: 628 RIVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLEE 687 Query: 302 GVLEGRRVFGNITKYIKMSSSSAFGNMLSVLGASAMLPFLPMAPVQILLNNLLYDFSQTT 361 GV+EGRR F N+ KYIKM++SS FGN+ SVL ASA LPFLPM P+ +L+ NLLYD SQ Sbjct: 688 GVIEGRRTFSNMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLLYDVSQVA 747 Query: 362 IATDHVDAEYLKQPRRWEILDIGRFMMVLGPVSSLFDYMTFGVLWYFFGA--AGQPLLFQ 419 I D+VD E +++P+RW D+GRFM+ GP+SS+FD +TF ++W+ F A LFQ Sbjct: 748 IPFDNVDEEQIQKPQRWNPADLGRFMVFFGPISSIFDILTFCLMWWVFHANTPETQTLFQ 807 Query: 420 SGWFVESLLSQTLVVHVIRTGKIPFVQSKPSLPLLATTAVICVLAFWLPASSIAHTLGLT 479 SGWFV LLSQTL+VH+IRT ++PF+QS+ + PL+A T ++ V+ LP S +A L L Sbjct: 808 SGWFVVGLLSQTLIVHMIRTRRLPFIQSRAAWPLMAMTLLVMVVGVSLPFSPLASYLQLQ 867 Query: 480 ALPLNLNAAILAIVFAYLLMTQLMKSWLIRRFGLK 514 ALPL+ ++AI+ Y+ +TQL+K + RR+G + Sbjct: 868 ALPLSYFPWLIAILVGYMTLTQLVKGFYSRRYGWQ 902 >BMEII0056 [P] COG0474 Cation transport ATPase Bme Brucella melitensis Length = 928 Score = 505 bits (1300), Expect = e-142, Method: Compositional matrix adjust. Identities = 258/510 (50%), Positives = 339/510 (66%), Gaps = 9/510 (1%) Query: 5 KVTRYAYLNSFFQTGLKNLLDMAILNYVDPGKKSATPAETKAETEKEFRKIDELPFDFER 64 KV R A+LNS+ Q+G+KNL+D A++++ + P E T + +RK+DELPFDF R Sbjct: 423 KVLRLAWLNSYHQSGVKNLMDQAVVSFAN-----RVPEEV-MRTARLYRKVDELPFDFIR 476 Query: 65 RRMSVIVEQADRTRLLICKGAPEEILAVCTHAEHAGAPMPLAGHHGAALSKTVDDLNEDG 124 RR+SV+VE LL+CKGA EE+LA+CT L L T N DG Sbjct: 477 RRLSVVVEGVGGEHLLVCKGAVEEMLAICTTVRDGETVRALDAVTREKLIATACAYNADG 536 Query: 125 FRVIAVAYKELPAATAEVPALGNADESALTLVGYIAFLDPPKDSAGEAIAGLHACGVTVK 184 FRV+ VA +E+P A ADE+ LT+ G++ FLDPPK++AG AIA L GV VK Sbjct: 537 FRVLVVATREIPGAETSA-QYRIADEAGLTVQGFLTFLDPPKETAGPAIAALAEHGVCVK 595 Query: 185 VLSGDNGAVVRNVCRHVGLSGEQAVLGSDIDTLSDEALGELAEHSNIFAKLNPQQKARII 244 VL+GDN V R +CR VGL +LGS+I+ L DEAL +AE +FAKL P QK+R++ Sbjct: 596 VLTGDNEIVTRKICREVGLEAGIPILGSEIEKLDDEALRVVAEERTVFAKLTPLQKSRVL 655 Query: 245 RCLQARRHVVGYLGDGINDGAALKAADVGISVDSAVDIAKESADIILMRKSLIVLKDGVL 304 + LQA H VG+LGDGIND AL+ ADVGISVDS DIAKESADIIL+ KSLIVL++GV+ Sbjct: 656 QALQANGHTVGFLGDGINDAPALRDADVGISVDSGADIAKESADIILLEKSLIVLEEGVV 715 Query: 305 EGRRVFGNITKYIKMSSSSAFGNMLSVLGASAMLPFLPMAPVQILLNNLLYDFSQTTIAT 364 GR FGNI KY+ M +SS FGN+ SVL ASA +PFLPM + +L+ NL+YD SQ + Sbjct: 716 TGRETFGNILKYLNMCASSNFGNVFSVLVASAFIPFLPMLAIHLLIQNLMYDISQLALPW 775 Query: 365 DHVDAEYLKQPRRWEILDIGRFMMVLGPVSSLFDYMTFGVLWYFFGAAGQPL--LFQSGW 422 D +D E+L +PR+W+ +IGRFM+ +GP SS+FD TF ++WY F A + LFQSGW Sbjct: 776 DKMDKEFLAKPRKWDARNIGRFMIWIGPTSSIFDITTFALMWYVFSANSPQMQSLFQSGW 835 Query: 423 FVESLLSQTLVVHVIRTGKIPFVQSKPSLPLLATTAVICVLAFWLPASSIAHTLGLTALP 482 F+E LLSQTLVVH++RT KIPF QS +LP++ +A+I L ++P S I +GL LP Sbjct: 836 FIEGLLSQTLVVHMLRTQKIPFFQSTAALPVMLMSALIIALGIYIPFSPIGEMVGLVPLP 895 Query: 483 LNLNAAILAIVFAYLLMTQLMKSWLIRRFG 512 + A + +Y L+ Q MK +RRFG Sbjct: 896 WAYFPWLAATLVSYCLVAQGMKVIYVRRFG 925