BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0204.p (326 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO2761 [GER] COG0697 Permeases of the drug/metabolite transport... 244 1e-64 AGpA485 [GER] COG0697 Permeases of the drug/metabolite transport... 230 3e-60 PA4287 [GER] COG0697 Permeases of the drug/metabolite transporte... 226 4e-59 RSp1638 [GER] COG0697 Permeases of the drug/metabolite transport... 201 2e-51 SMc00642 [GER] COG0697 Permeases of the drug/metabolite transpor... 139 1e-32 >YPO2761 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ype Yersinia pestis Length = 305 Score = 244 bits (624), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 141/287 (49%), Positives = 211/287 (73%), Gaps = 2/287 (0%) Query: 32 LYPFLAIVLWAGNVIVSKMAASAISPTAITFYRLILVLLLMSPFMLRPLWRNRAQIRRHW 91 L+P A+++W+ N +VSK++A+AI P AI+FYR +L LL +SPF+L + RN IR +W Sbjct: 4 LFPLFAVIIWSVNAVVSKISATAIDPAAISFYRWLLALLTLSPFLLLGVVRNWQAIRVYW 63 Query: 92 WQLGLSGLLAMALFQSLSYRAAESTTATNMAIVTALIPLLTALLSVIVLGEAITVGMAVG 151 W+L L G+L M L+QSL+Y AA S +A M I+++LIPLLT L+S+++L A TVG+A+G Sbjct: 64 WKLMLLGMLGMVLYQSLAYYAAHSVSALFMGILSSLIPLLTVLISIVLLRVAPTVGIALG 123 Query: 152 GLLSFTGLLYLVGHGDLGAAMREGVHLGDALMLLAAFSYALYGVLLRRWKMNVPVWQAVY 211 LLS GL++L+ G+ ++ G+ G+ +ML A+ SYALYGVL +RW + +P WQ++Y Sbjct: 124 SLLSLGGLVWLISAGNPVQLLQHGIGKGELMMLGASASYALYGVLTKRWAIQLPNWQSLY 183 Query: 212 VQAVAALVLMLPQFLLLPAGTAALDARTLPLIAYSGIGSSILLSFLWIEGVKKLGPNRCS 271 +Q V +VL+LP FL+ P L A+ +PL+ ++GI +SIL +LWI+GV +LG N S Sbjct: 184 MQIVFGVVLLLPGFLMTP--DVQLTAQNIPLVLFAGIPASILAPYLWIQGVMRLGANTAS 241 Query: 272 IFINLLPVLTALFAILWLNESMHAYHLIGGGVSLAGVLLTQIVQRPL 318 IF+NL PV TA+ A+++L+E +H+YHLIGGG++LAGV+L Q ++ PL Sbjct: 242 IFMNLTPVFTAIIAVVFLHEQLHSYHLIGGGITLAGVVLAQRLRSPL 288 >AGpA485 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 309 Score = 230 bits (586), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 132/309 (42%), Positives = 199/309 (64%), Gaps = 11/309 (3%) Query: 21 TTQTAMPLRSYLYPFLAIVLWAGNVIVSKMAASAISPTAITFYRLILVLLLMSPFMLRPL 80 + MP++ L+ LA+++W GN IVSK+AA AI+P I F R + ++++P + R Sbjct: 2 NKEAPMPVKYLLFSLLAVLIWVGNTIVSKLAAGAIAPGTIAFERWFIAFVILTPLVYRDA 61 Query: 81 WRNRAQIRRHWWQLGLSGLLAMALFQSLSYRAAESTTATNMAIVTALIPLLTALLSVIVL 140 WR+R I H +L L GLL MA Q L Y AA TTATNMAI+ +L+PLLT +LS + L Sbjct: 62 WRHRRTIAAHLPKLILLGLLGMAACQGLGYYAAGLTTATNMAIMLSLVPLLTLILSAVFL 121 Query: 141 GEAITVGMAVGGLLSFTGLLYLVGHGDLGAAMREGVHLGDALMLLAAFSYALYGVLLRRW 200 E + +GG++S +G+ ++G GD + +GV GDA+ML A +YA YG+LLRRW Sbjct: 122 AERPSSLAVIGGIISLSGIFIVLGQGDPSRLLSQGVGRGDAMMLAAVLAYAGYGILLRRW 181 Query: 201 KMNVPVWQAVYVQAVAALVLMLPQFLLLPAGTAALDARTLP---LIAYSGIGSSILLSFL 257 + + W ++YVQ AA+VL++P +LL +A A TLP ++ Y+ I SIL F+ Sbjct: 182 AIPLATWTSIYVQIGAAVVLLVPSYLL-----SAPSALTLPNTAMVLYAAIPGSILAPFV 236 Query: 258 WIEGVKKLGPNRCSIFINLLPVLTALFAILWLNESMHAYHLIGGGVSLAGVLLTQIVQRP 317 W+ VK LG R +IF+NL+P+ TA+ A ++L E+++ YHL+GGG+++AG++L VQR Sbjct: 237 WMTAVKHLGAARTAIFMNLIPIFTAIVAAIFLGEALYIYHLLGGGMTVAGIIL---VQRK 293 Query: 318 LFGARVGFR 326 F + G + Sbjct: 294 PFREKSGQK 302 >PA4287 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 296 Score = 226 bits (577), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 123/287 (42%), Positives = 193/287 (67%), Gaps = 2/287 (0%) Query: 30 SYLYPFLAIVLWAGNVIVSKMAASAISPTAITFYRLILVLLLMSPFMLRPLWRNRAQIRR 89 YL+P LA+ +WAGN +V+K+A I P I F+R +LV L ++PFML P+ RNR I Sbjct: 2 QYLFPLLAVFIWAGNTVVNKLAVGIIQPAEIGFFRWLLVGLALTPFMLGPVLRNRRYILA 61 Query: 90 HWWQLGLSGLLAMALFQSLSYRAAESTTATNMAIVTALIPLLTALLSVIVLGEAITVGMA 149 + + + GLL MA++QSL+Y AA T+ATNM I+ +L+PL++ L+ +L + G Sbjct: 62 NLGKFVVLGLLGMAVYQSLAYYAAALTSATNMGIILSLMPLMSLGLASSILAHRLNAGAL 121 Query: 150 VGGLLSFTGLLYLVGHGDLGAAMREGVHLGDALMLLAAFSYALYGVLLRRWKMNVPVWQA 209 +G L+S G++ ++ G LGA + GV+LGDA+M++A +YA+Y VLL++W + +P Q Sbjct: 122 LGALVSLAGVVLVISQGHLGALLEHGVNLGDAMMIVATLAYAVYSVLLKKWSLKLPAMQL 181 Query: 210 VYVQAVAALVLMLPQFLLLPAGTAALDARTLPLIAYSGIGSSILLSFLWIEGVKKLGPNR 269 +Y+Q + A++ +LP +LL P L+A LPL+ Y+ + +SI+ + W+ GV +LGP+R Sbjct: 182 LYLQVLVAILALLPLYLLSP--RTGLNAANLPLVLYAALFASIVAALAWMHGVARLGPSR 239 Query: 270 CSIFINLLPVLTALFAILWLNESMHAYHLIGGGVSLAGVLLTQIVQR 316 ++F NLLP++TA A L L E + +HL+GG ++LAGVLL + QR Sbjct: 240 MALFFNLLPIITACIATLVLGERLTVHHLVGGALTLAGVLLAEFWQR 286 >RSp1638 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 297 Score = 201 bits (511), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 115/288 (39%), Positives = 178/288 (61%), Gaps = 3/288 (1%) Query: 32 LYPFLAIVLWAGNVIVSKMAASAISPTAITFYRLILVLLLMSPFMLRPLWRNRAQIRRHW 91 YP LA+++WA N IVSK AA + P AI+ YR ++ +++PF RPLWR R + Sbjct: 4 FYPLLAVLVWAANTIVSKAAAGVLDPAAISLYRWVIAAAVLTPFWARPLWRQRRDVLPWL 63 Query: 92 WQLGLSGLLAMALFQSLSYRAAESTTATNMAIVTALIPLLTALLSVIVLGEAITVGMAVG 151 +L + LL + ++Q LSY AA ST+ATN+ ++ ALIP+L +++ +V + + G Sbjct: 64 PRLSVLALLGLVMYQCLSYYAAYSTSATNIGVICALIPMLGLIINGVVFRQPVGAPAVAG 123 Query: 152 GLLSFTGLLYLVGHGDLGAAMREGVHLGDALMLLAAFSYALYGVLLRRWKMNVPVWQAVY 211 +S G+LYL+G G + GV+ GD L+L+ + +YALY +L RRW W +Y Sbjct: 124 IAVSLLGVLYLLGRGHPASLFDGGVNRGDVLVLIGSAAYALYNILYRRWAPPFGQWLNLY 183 Query: 212 VQAVAALVLMLPQFLLLPAGTAALDARTLPLIAYSGIGSSILLSFLWIEGVKKLGPNRCS 271 +QA+ A+V++LP L A + A+ + + ++ ++GIG+SI+ + W+ G+ +LG R Sbjct: 184 LQALLAVVMLLP--LAFTARSLAIPQQGIGMVLFAGIGASIVAMYWWMLGLARLGSERTV 241 Query: 272 IFINLLPVLTALFAILWLNESMHAYHLIGGGVSLAGVLLTQ-IVQRPL 318 + +NLLPV TAL A L E++H YH IGGG+ L GV L Q IV P+ Sbjct: 242 VMMNLLPVFTALMASAMLGETIHGYHWIGGGLILLGVSLVQGIVTLPM 289 >SMc00642 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 296 Score = 139 bits (349), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 94/290 (32%), Positives = 152/290 (52%), Gaps = 5/290 (1%) Query: 26 MPLRSYLYPFLAIVLWAGNVIVSKMAASAISPTAITFYRLILVLLLMSPFMLRPLWRNRA 85 M R+Y Y + + W GN + KMA +SP +T R +L L ++ M + R+ Sbjct: 1 MNARAYFYLGITALFWGGNSVAGKMAVGHVSPMMLTTLRWLLALAVILVLMTPQIRRDWQ 60 Query: 86 QIRRHWWQLGLSGLLAMALFQSLSYRAAESTTATNMAIVTALIPLLTALLSVIVLGEAIT 145 +IR+HW QL G + +F + Y A + T+A N I+ A IP+L + + + + Sbjct: 61 KIRQHWLQLLAYGAVGFTMFNAFLYSAVQYTSAINAVILQAGIPMLIFIFNFALFKMKAS 120 Query: 146 VGMAVGGLLSFTGLLYLVGHGDLGAAMREGVHLGDALMLLAAFSYALYGVLLRRWKMNVP 205 + +G ++ G+L HGDL + MR + GDALM+LA YA Y V L RWK + Sbjct: 121 LAQVIGFTVTLVGVLITAAHGDLASLMRLSFNFGDALMILACIVYAAYTVAL-RWKPAMH 179 Query: 206 VWQA-VYVQAVAALVLMLPQFLL-LPAGTAAL-DARTLPLIAYSGIGSSILLSFLWIEGV 262 WQ+ + A AL+ +P L + GTA + DA ++ Y+ I S++ L++ GV Sbjct: 180 -WQSFIAAPAFGALLSAIPLLLWEMGKGTAIMPDATGWAIVIYAAIFPSLMSQVLYVRGV 238 Query: 263 KKLGPNRCSIFINLLPVLTALFAILWLNESMHAYHLIGGGVSLAGVLLTQ 312 + +G NR +FIN +PV L ++L + E H +HL + L G+ + + Sbjct: 239 EMIGANRAGLFINAIPVFGTLLSVLLVGEIFHPFHLAALALVLGGIAIAE 288