BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0192.p (485 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4132 [KE] COG1167 Transcriptional regulators containing a DNA-... 459 e-128 YPO1960 [KE] COG1167 Transcriptional regulators containing a DNA... 407 e-113 STM1598 [KE] COG1167 Transcriptional regulators containing a DNA... 375 e-103 RSc0599 [KE] COG1167 Transcriptional regulators containing a DNA... 371 e-102 ydcR [KE] COG1167 Transcriptional regulators containing a DNA-bi... 371 e-102 >PA4132 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Pae Pseudomonas aeruginosa Length = 471 Score = 459 bits (1180), Expect = e-128, Method: Compositional matrix adjust. Identities = 227/473 (47%), Positives = 316/473 (66%), Gaps = 6/473 (1%) Query: 13 YKKFADELAASIRAGVLQPGERVTSVRAASQQHNLSVTTVVRAYELLESRGIIESHPQSG 72 Y+KFADE+A IR GVL PG++V SVR AS+ + +S +TV +AY LLESRG+I + +SG Sbjct: 4 YEKFADEIAELIRTGVLAPGQKVPSVRHASRTYGVSASTVFQAYYLLESRGLIMARARSG 63 Query: 73 YFVRKTATPASVPAAMTLLPPSHPATQQPHEVDVSRLVLATLRTIQQDGTIPLGSPYPNP 132 YFV + +P P P EVDVS LV + L +I+ T+P GS +P+P Sbjct: 64 YFVCQHVQ-RPLPE-----PEISPRQADATEVDVSELVFSVLSSIKDPDTVPFGSAFPSP 117 Query: 133 ALFPSQRIGQYASRITRNSDSFSVFTDLPPGHPDLLRQIARRYLETGLAVDPEDIIITVG 192 LFP R+ + + R+ D SV D+ PG+ L RQIA RY+ GL + E+++I+ G Sbjct: 118 QLFPLPRLARSMAHAVRDMDPQSVVADMTPGNHGLRRQIALRYMVGGLLLPVEELVISNG 177 Query: 193 ATEAINLCLQAVAQPGDTIAVETPTFYAMLHAIERMGMRAVEIPTDPLTGIDLDALEELL 252 A EA+NLCLQ V +PGD +A+E P FYA L +ER+ ++AVEIP P GIDL+ L + L Sbjct: 178 ALEALNLCLQVVTRPGDLVAIEAPAFYATLQVLERLKLKAVEIPVHPREGIDLEVLADSL 237 Query: 253 KTQKISACMVMPNFQNPLGSMMPDAHKKRLVKLAHQHNMPLIEDAVYSELFYGAAHPTSL 312 + I AC M NFQNP+G+ M D K+ L +L +H +P+IED VY+EL++G P + Sbjct: 238 ERLPIKACWFMSNFQNPMGASMDDEKKRALAELLARHQVPMIEDDVYAELYFGQQAPKPV 297 Query: 313 KTYDRDGLVLHCSSFSKSLSSAYRVGWAIPGRYRNQVEKLKFLNTLATPTIPQRAIAEYL 372 K YD++GLV+HCSSFSKSL+ YRVGW GRY Q+E+LK + +L+ Q AIA+YL Sbjct: 298 KAYDQEGLVMHCSSFSKSLAPGYRVGWVAGGRYAEQIERLKLMTSLSASIPAQAAIADYL 357 Query: 373 TQGGYERHLRRVRRGLLQQRDLMRHFVLRFFPEGTRVSEPAGGYILWIELPPRVEAMELY 432 GGY+RHLR++R L Q++ M V R+FPE TRVS P+GGY LW+ELP V+++ L+ Sbjct: 358 QHGGYDRHLRKLRYALETQQNAMLAAVARYFPEQTRVSRPSGGYFLWLELPEAVDSLRLF 417 Query: 433 RRCLVLGITIAPGRIFAATNRYSNFIRLNYSYSWSAEIEKALKTIGKIVAELS 485 + L GI++APG IF+AT R+++ RLNY + WSA EKA++T+G+I L+ Sbjct: 418 QLALAQGISLAPGPIFSATRRFAHCARLNYGHPWSARQEKAMETLGRITQSLA 470 >YPO1960 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Ype Yersinia pestis Length = 473 Score = 407 bits (1047), Expect = e-113, Method: Compositional matrix adjust. Identities = 194/473 (41%), Positives = 301/473 (63%), Gaps = 7/473 (1%) Query: 13 YKKFADELAASIRAGVLQPGERVTSVRAASQQHNLSVTTVVRAYELLESRGIIESHPQSG 72 Y++ A ++ A I++ V Q G+++ S+R + +Q LS+ TVV++Y+LLES+G I + PQSG Sbjct: 4 YEQLAQQIRAQIQSKVWQAGDKLPSLRESCKQSGLSLMTVVQSYQLLESQGWIVARPQSG 63 Query: 73 YFVRKTATPASVPAAMTLLPPSHPATQQPHEVDVSRLVLATLRTIQQDGTIPLGSPYPNP 132 Y+V + P +P P +VD++ + L+ + +P GS +P+P Sbjct: 64 YYV--ASRPTQLPQ-----PQRGNKLHLDEQVDINTFIFNVLQAGKDPAIMPFGSAFPDP 116 Query: 133 ALFPSQRIGQYASRITRNSDSFSVFTDLPPGHPDLLRQIARRYLETGLAVDPEDIIITVG 192 +L R+ + + + R S T+LPPG+ L R IA+RY G+ V PE+I+IT G Sbjct: 117 SLLLQPRLSRALASVARKISPQSSVTNLPPGNESLRRNIAQRYAACGMNVSPEEIVITAG 176 Query: 193 ATEAINLCLQAVAQPGDTIAVETPTFYAMLHAIERMGMRAVEIPTDPLTGIDLDALEELL 252 A E+++L LQAV QPGD + +E+P FY L AIER+ ++A+ I TDP G+DL+ALE+++ Sbjct: 177 AMESLSLSLQAVTQPGDWVVIESPAFYGALQAIERLRLKAIAITTDPQQGVDLEALEQVI 236 Query: 253 KTQKISACMVMPNFQNPLGSMMPDAHKKRLVKLAHQHNMPLIEDAVYSELFYGAAHPTSL 312 I AC +MP+FQNP+G+ MP + K+RLV L Q + LIED VY EL++GA Sbjct: 237 SQYPIKACWLMPHFQNPMGATMPWSQKQRLVTLLQQKAISLIEDDVYGELYFGAERLLPA 296 Query: 313 KTYDRDGLVLHCSSFSKSLSSAYRVGWAIPGRYRNQVEKLKFLNTLATPTIPQRAIAEYL 372 K D+ +LHCSSFSK L+ +RVGW G + +++ L+ ++T++ Q AIA+YL Sbjct: 297 KALDQHRQILHCSSFSKCLAPGFRVGWVAAGEHAQRIQHLQLMSTVSASVPTQLAIADYL 356 Query: 373 TQGGYERHLRRVRRGLLQQRDLMRHFVLRFFPEGTRVSEPAGGYILWIELPPRVEAMELY 432 +QGGY+ HLRR+RR + Q+ + V+ FP+ ++S PAGGY LW+EL P A ELY Sbjct: 357 SQGGYDTHLRRLRRVMEQRMSTLHQAVVEHFPKNIKISHPAGGYFLWLELEPPFNASELY 416 Query: 433 RRCLVLGITIAPGRIFAATNRYSNFIRLNYSYSWSAEIEKALKTIGKIVAELS 485 RR L G++IAPGR+F +++ + RLN S++WS + KA++ + K++ +L+ Sbjct: 417 RRALEQGVSIAPGRMFTTGSQFDHCFRLNASFAWSEQSAKAIRILAKLIGQLT 469 >STM1598 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Sty Salmonella typhimurium LT2 Length = 474 Score = 375 bits (963), Expect = e-103, Method: Compositional matrix adjust. Identities = 185/472 (39%), Positives = 286/472 (60%), Gaps = 8/472 (1%) Query: 13 YKKFADELAASIRAGVLQPGERVTSVRAASQQHNLSVTTVVRAYELLESRGIIESHPQSG 72 Y++ A+++ I +GV QPG+R+ S+R +S TV AY+LLES+G I + PQSG Sbjct: 4 YQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSG 63 Query: 73 YFVRKTATPASVPAAMTLLPPSHPATQQPHEVDVSRLVLATLRTIQQDGTIPLGSPYPNP 132 Y+V SV A ++ + VD++ + L+ + +P S +P+P Sbjct: 64 YYVAPHPVCRSVATAAHVI--------RDEAVDINTYIFEMLQASRDTSVVPFASAFPDP 115 Query: 133 ALFPSQRIGQYASRITRNSDSFSVFTDLPPGHPDLLRQIARRYLETGLAVDPEDIIITVG 192 LFP ++ + +++++ + + SV +LPPG+ +L IARRY + G+ V P++I+IT G Sbjct: 116 RLFPLPQLNRSLAQVSKTATAMSVIENLPPGNAELRYAIARRYAQQGITVSPDEIVITAG 175 Query: 193 ATEAINLCLQAVAQPGDTIAVETPTFYAMLHAIERMGMRAVEIPTDPLTGIDLDALEELL 252 A EA+NL LQAV PGD + VE P FY L A+ER+ ++A+ IPTD GIDL ALE+ L Sbjct: 176 ALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDVKEGIDLMALEQAL 235 Query: 253 KTQKISACMVMPNFQNPLGSMMPDAHKKRLVKLAHQHNMPLIEDAVYSELFYGAAHPTSL 312 + + AC +M N QNPLG + K RLV L HN+ LIED VYSEL++G P Sbjct: 236 QEYPVKACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVTLIEDDVYSELYFGREKPLPA 295 Query: 313 KTYDRDGLVLHCSSFSKSLSSAYRVGWAIPGRYRNQVEKLKFLNTLATPTIPQRAIAEYL 372 K +DRD VLHCSSFSK L +R+GW G + Q+++L+ ++TL+T + Q A+ +YL Sbjct: 296 KAWDRDDTVLHCSSFSKCLVPGFRIGWVAGGSHARQIQRLQLMSTLSTSSPMQLALVDYL 355 Query: 373 TQGGYERHLRRVRRGLLQQRDLMRHFVLRFFPEGTRVSEPAGGYILWIELPPRVEAMELY 432 + Y+ HLRR+RR L +++ +LR P ++ GY LW+ELP +++A EL Sbjct: 356 STRRYDAHLRRLRRQLAERKQQAWQTLLRHLPAEVKIHHNDSGYFLWLELPEQLDAGELS 415 Query: 433 RRCLVLGITIAPGRIFAATNRYSNFIRLNYSYSWSAEIEKALKTIGKIVAEL 484 + L I+IAPG++F+ + ++ F R N ++ W E+A+K +G ++ E+ Sbjct: 416 AKALEHLISIAPGKMFSTSGAWTRFFRFNTAWHWGEREEQAVKQLGSLIREM 467 >RSc0599 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Rso Ralstonia solanacearum Length = 504 Score = 371 bits (953), Expect = e-102, Method: Compositional matrix adjust. Identities = 195/480 (40%), Positives = 287/480 (59%), Gaps = 12/480 (2%) Query: 11 PLYKKFADELAASIRAGVLQPGERVTSVRAASQQHNLSVTTVVRAYELLESRGIIESHPQ 70 PLY+ AD ++R+GVL PG+R+ SVR + H++S++T ++ LE+ G +E+ + Sbjct: 30 PLYRMLADHYLGAMRSGVLTPGQRMPSVRTLMRTHSVSLSTALQVCRHLEAEGWLEARER 89 Query: 71 SGYFVRKTATPASVPAAMTLLPPSHPATQQPHE---VDVSRLVLATL-RTIQQDGTIPLG 126 SGYFVR+ P L P P P V V V A + R +Q + L Sbjct: 90 SGYFVRQ-------PRRALLAPAKEPEVATPDPAAYVGVHARVSAIIARGLQARARVDLS 142 Query: 127 SPYPNPALFPSQRIGQYASRITRNSDSFSVFTDLPPGHPDLLRQIARRYLETGLAVDPED 186 L+PS + + A+++ R P GHPDL +ARR LE G+ V P+D Sbjct: 143 GASGAATLYPSAVLNRIATQMLRARPLLLTQAVTPNGHPDLQSAVARRALEMGVQVAPDD 202 Query: 187 IIITVGATEAINLCLQAVAQPGDTIAVETPTFYAMLHAIERMGMRAVEIPTDPLTGIDLD 246 +++T G EA+NL L+AVAQPGDT+AVE+PT+Y +L +E +GMRAVEIPT P TGI L+ Sbjct: 203 VVVTHGCIEAVNLALRAVAQPGDTVAVESPTYYGLLQVLECLGMRAVEIPTSPRTGISLE 262 Query: 247 ALEELLKT-QKISACMVMPNFQNPLGSMMPDAHKKRLVKLAHQHNMPLIEDAVYSELFYG 305 ALE ++ I A +V+PN QNPLGS+MPDA K+RL H +PLIED YS L G Sbjct: 263 ALEMAVQAYGNIRAVVVVPNLQNPLGSIMPDAAKRRLAAFCEAHAIPLIEDDTYSALGDG 322 Query: 306 AAHPTSLKTYDRDGLVLHCSSFSKSLSSAYRVGWAIPGRYRNQVEKLKFLNTLATPTIPQ 365 A ++K +DR G V++C+S +K+++ R+GW GR++ +VE LKF + + Q Sbjct: 323 PAPLKAIKAWDRTGNVIYCASLNKTIAPGLRLGWMTGGRWQERVEMLKFAQSRPNDSWSQ 382 Query: 366 RAIAEYLTQGGYERHLRRVRRGLLQQRDLMRHFVLRFFPEGTRVSEPAGGYILWIELPPR 425 A L G Y+RH+R +R+ L +QR+ M + FP GTR+S PAGG +W+ELP Sbjct: 383 VTAARLLASGAYDRHIRTLRQTLREQRERMAEAIAGCFPAGTRLSVPAGGVAMWVELPAS 442 Query: 426 VEAMELYRRCLVLGITIAPGRIFAATNRYSNFIRLNYSYSWSAEIEKALKTIGKIVAELS 485 V +M L+ L GI IAPG +F+ NR+ ++ R+ + ++AE+E AL +G++ +L+ Sbjct: 443 VSSMALFEMALAHGIRIAPGTMFSNLNRFDHYFRICFGLPYTAEVETALAQLGRLAHQLA 502 >ydcR [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Eco Escherichia coli K12 Length = 468 Score = 371 bits (952), Expect = e-102, Method: Compositional matrix adjust. Identities = 185/471 (39%), Positives = 288/471 (61%), Gaps = 8/471 (1%) Query: 13 YKKFADELAASIRAGVLQPGERVTSVRAASQQHNLSVTTVVRAYELLESRGIIESHPQSG 72 Y++ A++L I +G+ QPG+R+ S+R +S TV AY+LLES+G I + PQSG Sbjct: 4 YQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSG 63 Query: 73 YFVRKTATPASVPAAMTLLPPSHPATQQPHEVDVSRLVLATLRTIQQDGTIPLGSPYPNP 132 Y+V A +P A P P T+ VD++ + L+ + +P S +P+P Sbjct: 64 YYVAPQAI--KMPKA-----PVIPVTRD-EAVDINTYIFDMLQASRDPSVVPFASAFPDP 115 Query: 133 ALFPSQRIGQYASRITRNSDSFSVFTDLPPGHPDLLRQIARRYLETGLAVDPEDIIITVG 192 LFP Q++ + +++++ + + SV +LPPG+ +L + IARRY G+ + P++I+IT G Sbjct: 116 RLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYALQGITISPDEIVITAG 175 Query: 193 ATEAINLCLQAVAQPGDTIAVETPTFYAMLHAIERMGMRAVEIPTDPLTGIDLDALEELL 252 A EA+NL LQAV +PGD + VE P FY L A+ER+ ++A+ + TD GIDL ALE L Sbjct: 176 ALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELAL 235 Query: 253 KTQKISACMVMPNFQNPLGSMMPDAHKKRLVKLAHQHNMPLIEDAVYSELFYGAAHPTSL 312 + + AC +M N QNPLG + K +LV L +Q+N+ LIED VYSEL++G P Sbjct: 236 QEYPVKACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPA 295 Query: 313 KTYDRDGLVLHCSSFSKSLSSAYRVGWAIPGRYRNQVEKLKFLNTLATPTIPQRAIAEYL 372 K +DR VLHCSSFSK L +R+GW G++ ++++L+ ++TL+T + Q A+ +YL Sbjct: 296 KAWDRHDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYL 355 Query: 373 TQGGYERHLRRVRRGLLQQRDLMRHFVLRFFPEGTRVSEPAGGYILWIELPPRVEAMELY 432 + Y+ HLRR+RR L +++ +LR+ P ++ GY LW+ELP ++A EL Sbjct: 356 STRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYFLWLELPEPLDAGELS 415 Query: 433 RRCLVLGITIAPGRIFAATNRYSNFIRLNYSYSWSAEIEKALKTIGKIVAE 483 L I+IAPG++F+ +S F R N ++ W E+A+K +GK++ E Sbjct: 416 LAALTHHISIAPGKMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQE 466