BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0125.p (300 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0987 [GER] COG0697 Permeases of the drug/metabolite transport... 290 2e-78 SMb20040 [GER] COG0697 Permeases of the drug/metabolite transpor... 251 2e-66 mll1137 [GER] COG0697 Permeases of the drug/metabolite transport... 224 2e-58 BS_ydeK [GER] COG0697 Permeases of the drug/metabolite transport... 224 3e-58 AGc394 [GER] COG0697 Permeases of the drug/metabolite transporte... 223 3e-58 >RSc0987 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 313 Score = 290 bits (743), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 175/300 (58%), Positives = 217/300 (72%), Gaps = 13/300 (4%) Query: 2 NSESKGMWLGFIGVAIFSLTLPFTRVAVAELNPAFVAFGRAVVAAVCAIGMLWHLKAKLP 61 ++E +G+ LGFIGV IFS TLPFTR+AVAEL+ FVA AV+A++ A+ +L A Sbjct: 15 HAERRGLLLGFIGVTIFSQTLPFTRMAVAELDATFVALAHAVLASLLALALLAATGALRA 74 Query: 62 TRLQVRG-----LLITSLGVVVGFPLFSSIAMHYVPASHGAVVVGLLPLATALFGALRFG 116 R + RG L +T+ GVVVGFPLFSS+AM VPA+HGA++ GLLPLATALF A Sbjct: 75 AR-RPRGGQWGRLAVTAAGVVVGFPLFSSLAMRDVPAAHGAIITGLLPLATALFAAWFGR 133 Query: 117 ERPSTGFWIAALIGSFIVIAFALRQGGGSFHTADFALFAAVVAAAMGYAEGGRLSQSMGG 176 ERPS FW AL GS +V++FAL +G G+ H AD+ LFAA+VA A+GYA GG+LS+ +GG Sbjct: 134 ERPSPWFWACALAGSVLVVSFALLRGAGTLHRADWLLFAAMVAGALGYAVGGKLSRELGG 193 Query: 177 QQVICWALVLSMPVLLPVT---IWL-GMHYGVA---ASPQAWMSFAYVSFFSMFIGFFFW 229 Q I WALV+S+P LLPV WL G H A AS AW+ AYVS FSMF+GF FW Sbjct: 194 TQTIAWALVVSLPALLPVVGALAWLPGTHQAAALAQASGHAWLGLAYVSAFSMFVGFLFW 253 Query: 230 YKGLALGGIARVGQVQLLQPFMTLVGAAVIVGETLDASHLLFATAVIAVVAIGRRMAIRR 289 Y GLA GG+ARVGQ+QLLQPFMTL+G +++GE LDA +LFA AVIAVV +GRR A+RR Sbjct: 254 YSGLAAGGVARVGQIQLLQPFMTLIGGWLLLGEPLDAPTMLFALAVIAVVGLGRRTAVRR 313 >SMb20040 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 286 Score = 251 bits (641), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 136/286 (47%), Positives = 185/286 (64%) Query: 1 MNSESKGMWLGFIGVAIFSLTLPFTRVAVAELNPAFVAFGRAVVAAVCAIGMLWHLKAKL 60 MN + G G IGV IFS +LP TRVAV + +P F+ RA +A + A +L+ + + Sbjct: 1 MNKATSGWMSGLIGVVIFSGSLPATRVAVMDFDPIFLTVARATIAGILAFCLLFAFRERR 60 Query: 61 PTRLQVRGLLITSLGVVVGFPLFSSIAMHYVPASHGAVVVGLLPLATALFGALRFGERPS 120 P R + L + SLGVVVGFPL +++A+ +V ++H V +GLLPLATA+FG LR GERP Sbjct: 61 PARGDLASLAVISLGVVVGFPLMTALALRHVTSAHSIVFIGLLPLATAIFGVLRGGERPR 120 Query: 121 TGFWIAALIGSFIVIAFALRQGGGSFHTADFALFAAVVAAAMGYAEGGRLSQSMGGQQVI 180 FW+ + +GS IV+ FA RQG + D + AA+VA +GYAEG +LS+ +GG QVI Sbjct: 121 PTFWVFSGLGSAIVVGFAARQGFSASPIGDLLMLAAIVACGLGYAEGAKLSRRLGGWQVI 180 Query: 181 CWALVLSMPVLLPVTIWLGMHYGVAASPQAWMSFAYVSFFSMFIGFFFWYKGLALGGIAR 240 CWALVLS+PV+ + + S +W+ F YVS FSM IGF FWY+GLALGGI Sbjct: 181 CWALVLSLPVMTALMLATMPSSLAGPSAASWLGFGYVSVFSMLIGFIFWYRGLALGGIVA 240 Query: 241 VGQVQLLQPFMTLVGAAVIVGETLDASHLLFATAVIAVVAIGRRMA 286 VGQ+QLLQPF L A+ ++GE + S L A++A VA ++ A Sbjct: 241 VGQLQLLQPFFGLALASTLLGENVSWSMLAATVAIVACVAGAKKFA 286 >mll1137 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 291 Score = 224 bits (571), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 130/286 (45%), Positives = 178/286 (62%) Query: 1 MNSESKGMWLGFIGVAIFSLTLPFTRVAVAELNPAFVAFGRAVVAAVCAIGMLWHLKAKL 60 M+ + G GFIGV IFS +LP TRVAV + +P FV RA +A + + ML + K Sbjct: 5 MDKTASGWVNGFIGVLIFSGSLPATRVAVMDFDPTFVTSARAAIAGLLGLAMLLLFREKR 64 Query: 61 PTRLQVRGLLITSLGVVVGFPLFSSIAMHYVPASHGAVVVGLLPLATALFGALRFGERPS 120 P R + L+I +LGVVVGFPL +++A+ ++ ++H + +GLLPLATA+FG LR G+RP Sbjct: 65 PDRGDLVSLVIVALGVVVGFPLLTALALKHITSAHSIIFIGLLPLATAIFGVLRGGDRPR 124 Query: 121 TGFWIAALIGSFIVIAFALRQGGGSFHTADFALFAAVVAAAMGYAEGGRLSQSMGGQQVI 180 W+ + IGS +V FAL QG + D + AAV+ +GYAEG LS+ +GG QVI Sbjct: 125 PALWLFSCIGSALVAGFALTQGVTASPVGDGLMLAAVIVCGLGYAEGAALSRRLGGWQVI 184 Query: 181 CWALVLSMPVLLPVTIWLGMHYGVAASPQAWMSFAYVSFFSMFIGFFFWYKGLALGGIAR 240 CWAL LS+PV+L ++ A AW+ YVS FSM IGF FWY+GLA GGIA Sbjct: 185 CWALTLSLPVMLVLSFATLPPSFAAVGSHAWIGLGYVSLFSMLIGFVFWYRGLAQGGIAA 244 Query: 241 VGQVQLLQPFMTLVGAAVIVGETLDASHLLFATAVIAVVAIGRRMA 286 VGQ+QLLQPF L AA ++ E + ++ V+A V ++ A Sbjct: 245 VGQLQLLQPFFGLALAASLLHEQVSPLMVVVTLGVVACVFGAKKFA 290 >BS_ydeK [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bsu Bacillus subtilis Length = 287 Score = 224 bits (570), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 138/286 (48%), Positives = 187/286 (65%) Query: 1 MNSESKGMWLGFIGVAIFSLTLPFTRVAVAELNPAFVAFGRAVVAAVCAIGMLWHLKAKL 60 MN + G GFIGV IFS +LP TR+AV++ +P F+ RA +A V A G+L + + Sbjct: 1 MNKTTNGWINGFIGVLIFSGSLPATRLAVSDFDPLFLTVCRAAIAGVLAGGLLLIFRQQH 60 Query: 61 PTRLQVRGLLITSLGVVVGFPLFSSIAMHYVPASHGAVVVGLLPLATALFGALRFGERPS 120 P + + LL+ + GVV+GFPL +++A+ +V ++H V +GLLPLATA+FG LR GERP Sbjct: 61 PAKRDLISLLVVAFGVVIGFPLLTALALQHVTSAHAIVFIGLLPLATAVFGVLRGGERPR 120 Query: 121 TGFWIAALIGSFIVIAFALRQGGGSFHTADFALFAAVVAAAMGYAEGGRLSQSMGGQQVI 180 FWI + GS +V FAL QGGGS D + A++V +GYAEG +LS+ +G QVI Sbjct: 121 PVFWIFSAAGSLLVAGFALIQGGGSSPLGDAYMLASIVVCGLGYAEGAKLSRRLGNWQVI 180 Query: 181 CWALVLSMPVLLPVTIWLGMHYGVAASPQAWMSFAYVSFFSMFIGFFFWYKGLALGGIAR 240 WALVLS+P++LP++ + A A +S AYVS FSM IGF FWY+GLA GGIA Sbjct: 181 SWALVLSLPLMLPLSFFFTPDSWSAIGVPALLSLAYVSLFSMLIGFVFWYRGLAQGGIAA 240 Query: 241 VGQVQLLQPFMTLVGAAVIVGETLDASHLLFATAVIAVVAIGRRMA 286 VGQ+QLLQPF L+ A+VI+ E + + + AVI VA RR A Sbjct: 241 VGQLQLLQPFFGLLLASVILHEKVGWALVAVNIAVIMCVAAARRFA 286 >AGc394 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 291 Score = 223 bits (569), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 129/290 (44%), Positives = 179/290 (61%), Gaps = 4/290 (1%) Query: 1 MNSESKGMWLGFIGVAIFSLTLPFTRVAVAELNPAFVAFGRAVVAAVCAIGMLWHLKAKL 60 M+ + G G GV IFS +LP TR+AV +P F+ RA +A + A+ +L+ + K Sbjct: 1 MDKTTSGWLNGLTGVVIFSGSLPATRLAVTGFDPVFLTAARASIAGLLALALLFLFRQKR 60 Query: 61 PTRLQVRGLLITSLGVVVGFPLFSSIAMHYVPASHGAVVVGLLPLATALFGALRFGERPS 120 P R + L+I S+GVVVGFPL +++A+ +V ++H + VGLLPLATA+F +R GERP Sbjct: 61 PARGDLTSLIIVSIGVVVGFPLLTALALRHVTSAHSIIFVGLLPLATAIFAVMRGGERPR 120 Query: 121 TGFWIAALIGSFIVIAFALRQGGGSFHTA----DFALFAAVVAAAMGYAEGGRLSQSMGG 176 FW+ + +GS +V F+L + A D + A++ +GYAEG LS+ +GG Sbjct: 121 PVFWLFSCLGSALVAGFSLSNSFAARIEASLAGDLLMLGAIIVCGLGYAEGAALSRKLGG 180 Query: 177 QQVICWALVLSMPVLLPVTIWLGMHYGVAASPQAWMSFAYVSFFSMFIGFFFWYKGLALG 236 QVI WALVLS+PV+LP+ + G PQAW AYVS FSM IGF FWY+GLALG Sbjct: 181 WQVISWALVLSLPVMLPLAFFTGPETLGGIDPQAWGGLAYVSLFSMLIGFIFWYRGLALG 240 Query: 237 GIARVGQVQLLQPFMTLVGAAVIVGETLDASHLLFATAVIAVVAIGRRMA 286 GIA VGQ+QLLQPF L AA ++ E + + + V+ VA R+ A Sbjct: 241 GIAAVGQLQLLQPFFGLALAATLLHEEVSPAMIGVTLVVVLCVAGARKFA 290