BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0019.p (438 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1093 [GEPR] COG0477 Permeases of the major facilitator superf... 313 4e-85 PA0235 [GEPR] COG0477 Permeases of the major facilitator superfa... 286 9e-77 RSp0896 [GEPR] COG0477 Permeases of the major facilitator superf... 282 1e-75 PA2006 [GEPR] COG0477 Permeases of the major facilitator superfa... 258 2e-68 Z3394 [GEPR] COG0477 Permeases of the major facilitator superfam... 256 5e-68 >RSc1093 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 454 Score = 313 bits (803), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 180/430 (41%), Positives = 255/430 (59%), Gaps = 6/430 (1%) Query: 3 SAVINVDQVVEQSRFGPFQFGLLLLCGLCLIIDGFDIQAMGYVAPAIIGDWHVNKASLGP 62 S VI+V +++ RF FQ+ ++LLC + IDGFD +G++APA+ DWH+ A LG Sbjct: 5 SPVIDVRAWLDRQRFSAFQWSVVLLCFFVVAIDGFDTACVGFIAPALAQDWHIGPAVLGT 64 Query: 63 VFGAGLFGMLLGSLVLTPVGDKYGRRPVLIISTFFFAVCMLLTTRVQTIDELLILRFITG 122 VF AGL G+++G+L+ P+ D+ GR+ L+ + F + +L+ ++ L+ LRF+TG Sbjct: 65 VFSAGLAGLMVGALIFGPLADRIGRKQTLLFTVGAFGLASVLSAFAPSVGALVALRFLTG 124 Query: 123 FGLGSIMPNAMALVGEFSPNSSRVTRMMLVSCGFTVGAAVGGFVSAALIPAFGWRSVFLV 182 GLG MPNA+AL E+ P R ++ CGFT+G+ GG V+A L+P FGWRSV L Sbjct: 125 LGLGGAMPNAIALTSEYCPERRRAFLTTVMFCGFTLGSGFGGIVAAQLVPEFGWRSVLLF 184 Query: 183 GGLIPAALGVAMLLWLPESIQFLVLRKRPMKQVARWLNKVQPGLQVTESSTVVVKEARND 242 GG+IP L M+ LPES+++LV + V R LN++ P +QVT + V+ E Sbjct: 185 GGVIPLLLLPVMVFALPESVRYLVAKGGQSAAVGRLLNRIAP-VQVTPDTRFVLHETAAK 243 Query: 243 GM---PVAELFRDGRAGVTLLLWLISFMNLINLYFLSNWLPTLIKDAGYSTGAAVLIGTS 299 G PV +LF TLLLW + FM+L+ +Y ++NWLPTLI G + A I Sbjct: 244 GAPGSPVRQLFLPAFRTGTLLLWSVFFMSLLIVYLMTNWLPTLIHSGGVALALASRIAVM 303 Query: 300 LQVGGIVGTLTLGWFINRFGFTRVLGSCFVVACVFIALIGHVAATPVLLFICVVVAGFCV 359 Q+GG VG L +G ++R+ T VL + + F+ L G T +L I V GFC+ Sbjct: 304 YQLGGTVGALVIGRMMDRYPATVVLCCTYGLGAGFLVLTGVSQGT--MLAIAVTGVGFCI 361 Query: 360 VGGQPAVNALAGTFYPTQLRSTGIGWALGIGRVGSVLGPVIGGQLIAMQWANGSLFMAAA 419 G Q NA A FYPT R TGI WALGIGR+GSV G +IGG L+A LF+ A Sbjct: 362 SGSQIGANAFAAQFYPTASRVTGISWALGIGRLGSVCGALIGGVLLAANIGFQLLFLLVA 421 Query: 420 VPAIVSALMV 429 VPA +++L + Sbjct: 422 VPAAIASLAI 431 >PA0235 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 448 Score = 286 bits (731), Expect = 9e-77, Method: Compositional matrix adjust. Identities = 170/411 (41%), Positives = 250/411 (60%), Gaps = 13/411 (3%) Query: 6 INVDQVVEQSRFGPFQFGLLLLCGLCLIIDGFDIQAMGYVAPAIIGDWHVNKASLGPVFG 65 ++V + P+Q+ ++LLC L + +DG D AMG++APA+ DW +++ASLGPV Sbjct: 12 LDVQAFINAQPLSPYQWRIVLLCFLIVFLDGLDTAAMGFIAPALTQDWGIDRASLGPVMS 71 Query: 66 AGLFGMLLGSLVLTPVGDKYGRRPVLIISTFFFAVCMLLTTRVQTIDELLILRFITGFGL 125 A L GM+ G+L P+ D+YGR+ VL+ + F F + L + +++LL LRF+TG GL Sbjct: 72 AALIGMVFGALGSGPLADRYGRKLVLVAAVFLFGLFSLASAYSTNVEQLLALRFLTGLGL 131 Query: 126 GSIMPNAMALVGEFSPNSSRVTRMMLVSCGFTVGAAVGGFVSAALIPAFGWRSVFLVGGL 185 G+ MPNA L+ E++P + + + CGF +G A GGFVSA LIP FGW S+ L+GGL Sbjct: 132 GAAMPNATTLLSEYTPERLKSLLVTSMFCGFNLGMACGGFVSAKLIPLFGWHSLLLLGGL 191 Query: 186 IPAALGVAMLLWLPESIQFLVLRKRPMKQVARWLNKVQPG-------LQVTESSTVVVKE 238 +P L V +L LPES ++LV+R R ++V + L + P V E TV + Sbjct: 192 LPLVLAVVLLFRLPESARYLVVRNRGSERVRQVLAPIAPAQVALARSFHVPEQQTV---Q 248 Query: 239 ARNDGMPVAELFRDGRAGVTLLLWLISFMNLINLYFLSNWLPTLIKDAGYSTGAAVLIGT 298 ARN A +F + TLLLWL FM L+ +Y L++WLPTL++D+G S A IG Sbjct: 249 ARN---VFAVIFSGTYSAGTLLLWLTYFMGLVIVYLLTSWLPTLMRDSGASLEQAAFIGA 305 Query: 299 SLQVGGIVGTLTLGWFINRFGFTRVLGSCFVVACVFIALIGHVAATPVLLFICVVVAGFC 358 Q GG++ + +GW ++RF +V+G +++A VF +G LL V++AG C Sbjct: 306 LFQFGGVLSAVAVGWAMDRFNPHKVIGLFYLLAGVFAWCVGQSLGQVTLLATLVLLAGMC 365 Query: 359 VVGGQPAVNALAGTFYPTQLRSTGIGWALGIGRVGSVLGPVIGGQLIAMQW 409 + G Q A+ +LA FYPTQ R+TG+ W LGIGR G++LG IG L+ + W Sbjct: 366 INGAQSAMPSLAARFYPTQGRATGVSWMLGIGRFGAILGAWIGATLLGLGW 416 >RSp0896 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 458 Score = 282 bits (721), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 157/420 (37%), Positives = 238/420 (56%), Gaps = 3/420 (0%) Query: 4 AVINVDQVVEQSRFGPFQFGLLLLCGLCLIIDGFDIQAMGYVAPAIIGDWHVNKASLGPV 63 A + V +V++ SR +Q +L LC ++DGFD A+GY+APA+ WH+ L P Sbjct: 8 ADVPVREVIDGSRLSAYQGLVLALCFAAAMLDGFDTAAIGYIAPALREAWHLTPPQLAPA 67 Query: 64 FGAGLFGMLLGSLVLTPVGDKYGRRPVLIISTFFFAVCMLLTTRVQTIDELLILRFITGF 123 FGAGLFG++LGS+ L PV D++GR+PVL++S F V L +++ L++LRF+TG Sbjct: 68 FGAGLFGLMLGSMGLGPVADRFGRKPVLLMSVLVFGVATLACAASDSLNTLVMLRFLTGL 127 Query: 124 GLGSIMPNAMALVGEFSPNSSRVTRMMLVSCGFTVGAAVGGFVSAALIPAFGWRSVFLVG 183 GLG MP + L E+SP R+ + L GFT G A+GG V+A ++P +GWR V + G Sbjct: 128 GLGGAMPICITLSAEYSPQRHRMLLVTLSWSGFTSGLALGGLVAAEILPVYGWRGVLVAG 187 Query: 184 GLIPAALGVAMLLWLPESIQFLVLRKRPMKQVARWLNKVQPGLQVTESSTVVVKEARNDG 243 G+ P L + LW+PES+QFL R + + + + ++ G + T + +G Sbjct: 188 GVTPLVLLPVLALWMPESVQFLAQRPQCADALRQIVTRIA-GHDHGDGVTFIGDRPAQEG 246 Query: 244 MPVA--ELFRDGRAGVTLLLWLISFMNLINLYFLSNWLPTLIKDAGYSTGAAVLIGTSLQ 301 P LF DG A T+LLW F +L Y L++WLP +++D G + A +G + Sbjct: 247 APFPGRNLFSDGMAQRTVLLWAAFFCSLFVFYLLTSWLPVVMRDQGLTLTEAARVGAMVP 306 Query: 302 VGGIVGTLTLGWFINRFGFTRVLGSCFVVACVFIALIGHVAATPVLLFICVVVAGFCVVG 361 +GG +G + L ++R G R L + + + +A IG L V V GF + G Sbjct: 307 LGGTIGAIALALLMDRAGSPRALIAAYFCGAIAVAAIGLAIGNVAALTAVVFVVGFGIAG 366 Query: 362 GQPAVNALAGTFYPTQLRSTGIGWALGIGRVGSVLGPVIGGQLIAMQWANGSLFMAAAVP 421 Q +N LA YPT+ R+TG+ WALG+GR GS+ G ++GG L+ + +LF A+P Sbjct: 367 AQNGINLLAAQMYPTEARATGVSWALGVGRGGSITGSLVGGTLMTTVGSVQTLFGIIALP 426 >PA2006 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 450 Score = 258 bits (658), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 169/430 (39%), Positives = 258/430 (60%), Gaps = 4/430 (0%) Query: 1 MQSAVINVDQVVEQSRFGPFQFGLLLLCGLCLIIDGFDIQAMGYVAPAIIGDWHVNKASL 60 M + + + ++ +Q+ LLLL L L+ DG+D Q +GYV P + +W ++KA+ Sbjct: 1 MHNQIASFRAALDARPVSRYQWLLLLLLALLLVTDGYDAQVLGYVVPTLAQEWGLDKAAF 60 Query: 61 GPVFGAGLFGMLLGSLVLTPVGDKYGRRPVLIISTFFFAVCMLLTTRVQTIDELLILRFI 120 GPVF A LFG+ +GSL++TP+ D++G R VL+ +A +L +++ L++ RF+ Sbjct: 61 GPVFSANLFGLTVGSLLVTPLADRFGIRRVLLCCVLIYASLTVLMVFAGSLESLMLARFV 120 Query: 121 TGFGLGSIMPNAMALVGEFSPNSSRVTRMMLVSCGFTVGAAVGGFVSAALIPAFGWRSVF 180 G G+G MP+AMAL+ E+SP R + L +CGF+ G A GGFV+AA + FGW++VF Sbjct: 121 CGIGMGGAMPSAMALMAEYSPPRLRTLMVTLAACGFSFGGAAGGFVAAAFMDGFGWQAVF 180 Query: 181 LVGGLIPAALGVAMLLWLPESIQFLVLRKRPMKQVARWLNKVQPGLQVTESSTVVVKEAR 240 L GG+ P L +LL+LPES+ L+ P ++ + ++ PG Q + A Sbjct: 181 LAGGVTPLLLFPFLLLFLPESLPRLLRDAPPYARLRQLSERMAPGWQPPPAEADAEPAA- 239 Query: 241 NDGMPVAELFRDGRAGVTLLLWLISFMNLINLYFLSNWLPTLIKDAGYSTGAAVLIGTSL 300 + V ELFR G A TLLLW F++LI LYF+ +WLP+L++++G + AA L + Sbjct: 240 --SLTVLELFRHGYARPTLLLWATFFVSLILLYFMVSWLPSLLQESGLTRNAANLATSMF 297 Query: 301 QVGGIVGTLTLGWFINRF-GFTRVLGSCFVVACVFIALIGHVAATPVLLFICVVVAGFCV 359 G +G + L W +R R+L + A +F L+G P L V AGFC+ Sbjct: 298 LFAGTLGAMLLAWLADRLRSKVRLLAAILAGAALFTLLLGLNHDQPRWLLAFVFAAGFCI 357 Query: 360 VGGQPAVNALAGTFYPTQLRSTGIGWALGIGRVGSVLGPVIGGQLIAMQWANGSLFMAAA 419 +GGQ +NA A FYP Q+R+TG GWALG+GR GS+LGP+ G L+ M + ++FM AA Sbjct: 358 IGGQLTLNAFASNFYPAQVRATGTGWALGVGRFGSILGPLFGSLLLGMHISVENIFMLAA 417 Query: 420 VPAIVSALMV 429 +PA ++AL++ Sbjct: 418 IPAGLAALLI 427 >Z3394 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 452 Score = 256 bits (655), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 146/426 (34%), Positives = 249/426 (58%), Gaps = 1/426 (0%) Query: 7 NVDQVVEQSRFGPFQFGLLLLCGLCLIIDGFDIQAMGYVAPAIIGDWHVNKASLGPVFGA 66 ++ +++ + G Q+ +++ C L +++DGFD A+G++AP I W + L P+FGA Sbjct: 6 DLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLSPLFGA 65 Query: 67 GLFGMLLGSLVLTPVGDKYGRRPVLIISTFFFAVCMLLTTRVQTIDELLILRFITGFGLG 126 GL + G+L+ P+ D++GR+ V+ + F F L + + L+ LRF+TG GLG Sbjct: 66 GLLXLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLG 125 Query: 127 SIMPNAMALVGEFSPNSSRVTRMMLVSCGFTVGAAVGGFVSAALIPAFGWRSVFLVGGLI 186 MPN + + E+ P R + L+ CGFT+G+A GG VSA L+P GW + ++GG++ Sbjct: 126 GAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVL 185 Query: 187 PAALGVAMLLWLPESIQFLVLRKRPMKQVARWLNKVQPGLQVTESSTVVVKEARNDGMPV 246 P L VA+L+ LPES ++ V R+ P +A+ ++ + V ++ +++ A + Sbjct: 186 PLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYV-DTHFYLIESASVTKGSI 244 Query: 247 AELFRDGRAGVTLLLWLISFMNLINLYFLSNWLPTLIKDAGYSTGAAVLIGTSLQVGGIV 306 +LF + +TL+LW++ FM+L+ +Y LS+W+PTL+ G A + + Q+GG + Sbjct: 245 RQLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQIGGTL 304 Query: 307 GTLTLGWFINRFGFTRVLGSCFVVACVFIALIGHVAATPVLLFICVVVAGFCVVGGQPAV 366 G L LG +++F RVL + + + I +IG L+ + + G + G Q + Sbjct: 305 GALALGVLMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGL 364 Query: 367 NALAGTFYPTQLRSTGIGWALGIGRVGSVLGPVIGGQLIAMQWANGSLFMAAAVPAIVSA 426 NAL T YPTQ R+TG+ W+ IGR G+++G + GG ++AM ++ +LF AVPA +SA Sbjct: 365 NALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISA 424 Query: 427 LMVARL 432 +M+ L Sbjct: 425 VMLTLL 430