BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0010.p (448 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC2354 [GEPR] COG0477 Permeases of the major facilitator superfa... 308 2e-83 RSp0182 [GEPR] COG0477 Permeases of the major facilitator superf... 301 2e-81 RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 298 1e-80 AGc4908 [GEPR] COG0477 Permeases of the major facilitator superf... 297 4e-80 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 296 5e-80 >CC2354 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 430 Score = 308 bits (789), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 171/433 (39%), Positives = 255/433 (58%), Gaps = 8/433 (1%) Query: 1 MEAATSAVEKSAIRKVSLRLVPFVALMFFINFLDRTAISFAGPNGMTKDLALTAAQFGFA 60 M +SA+E++ + +V+ RL+P LM+ I ++DR +S+A + M L L+ A +G Sbjct: 1 MSDPSSALERATVGRVTRRLMPLFCLMYLIAYIDRQNVSYAKLD-MVSALGLSEAAYGLG 59 Query: 61 AGVFFIGYVLLEIPSNLALHKYGARRWLARIMVTWGIVALLFTWVSNVEGLYVLRFLLGV 120 A +FFIGY L E P+NL L + GAR W ARIM +WG+V L + N YVLRFLLGV Sbjct: 60 ASLFFIGYFLFEAPANLILARVGARVWFARIMFSWGLVTLALGFTQNAAMFYVLRFLLGV 119 Query: 121 AEAGFFPGAILFLSMWVPARHRSHILALFYLAQPLTIVIGAPVAALLIEAHGLFGLEGWR 180 AEAGFFPG + L++W P HR+ ++ LF +A +GA + LL+ G GL GW+ Sbjct: 120 AEAGFFPGVLYVLTLWYPQAHRARMVGLFMIASAFANAVGAAIGGLLLGMDGFLGLAGWQ 179 Query: 181 VMFAGVAIPAIVVGVIAWFYLADKPADAKWLNEAERNWLTAALASENKTKRITAQSNVTS 240 +F PA+++ + L P+DA+WL + E++WL + LA+E + + Sbjct: 180 WVFLVTGAPAVLLAPYVLWRLPSGPSDARWLPDVEKSWLASTLAAE-RGGEVDDHRGAWK 238 Query: 241 ALTNSRVWLLSLVYFGLIYGLYALAFFLPTIIGGFEAQFGSKFNVFQKGLITAIPYLPAA 300 A+ + RV +L+ +Y G+ Y L+++LPTI+ FG V G I IP+L A Sbjct: 239 AIFDPRVLMLAGLYIGMPLSAYGLSYWLPTIV----KSFGVSNTV--NGFINVIPWLLVA 292 Query: 301 VALYLWSRDATHRGVRSWHVGVPALLGAVSIPMALYMNTPAATVAAITVTACAIFSALPT 360 VAL+ R A G +WH+ P LL AV++ +++ + A + + A AIF+A P Sbjct: 293 VALWFVPRHAARHGASAWHIAGPVLLAAVALSLSVILPGAALKFTMLCIAAPAIFAAQPV 352 Query: 361 FWSIPGRFLSGAAAAAGIALINTVGNAAGFIAPFVTGAIKDATGSYQAPMFVVGALMLMS 420 FWS+P FLSG AAAGIA IN VGN GFIA + ++DATGS APM + A++L++ Sbjct: 353 FWSLPPSFLSGPRAAAGIATINAVGNLGGFIAQNLVPVVRDATGSELAPMLALAAVLLVT 412 Query: 421 AVVIFAIGAGARQ 433 +++IF + R+ Sbjct: 413 SLLIFIVMGRLRK 425 >RSp0182 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 453 Score = 301 bits (770), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 158/397 (39%), Positives = 244/397 (61%), Gaps = 5/397 (1%) Query: 9 EKSAIRKVSLRLVPFVALMFFINFLDRTAISFAGPNGMTKDLALTAAQFGFAAGVFFIGY 68 E++ +RK++ R++PFV ++ I++LDR I +A M ++LAL++ FGF +G+FFIGY Sbjct: 26 ERAIVRKITWRILPFVFALYIISYLDRANIGYAALQ-MNQELALSSEAFGFVSGIFFIGY 84 Query: 69 VLLEIPSNLALHKYGARRWLARIMVTWGIVALLFTWVSNVEGLYVLRFLLGVAEAGFFPG 128 L E+PSNL L+++GARRW+ARI+VTWG+VA+ +V + LY LRFLLGVAEAGFFPG Sbjct: 85 FLFEVPSNLMLNRFGARRWIARILVTWGLVAMGSAFVQSATQLYALRFLLGVAEAGFFPG 144 Query: 129 AILFLSMWVPARHRSHILALFYLAQPLTIVIGAPVAALLIEAHGLFGLEGWRVMFAGVAI 188 I++L+ W AR + +ALF A P++ V+GAP++ +++ GWR M Sbjct: 145 IIVYLTYWFRARELATTVALFTAAIPVSYVVGAPLSTWIMDHVHWLQWSGWRWMLLLEGA 204 Query: 189 PAIVVGVIAWFYLADKPADAKWLNEAERNWLTAALASENKTKRITAQSNVTSALTNSRVW 248 PA++ G++ + YLAD+P DA+WL+EAER+WL A L + K + A +T+ RV Sbjct: 205 PAVIGGLLCYGYLADRPKDARWLSEAERDWLLAELERDRKARPAAAHLATLKVMTHPRVL 264 Query: 249 LLSLVYFGLIYGLYALAFFLPTIIGGFEAQFGSKFNVFQKGLITAIPYLPAAVALYLWSR 308 L+ +YF G + +++P II GF S + + GLI +PY+ A + WSR Sbjct: 265 YLAFIYFVYQCGSLGIGYWMPQIIKGFS----SALSHTEVGLIAMLPYVFATAVMIWWSR 320 Query: 309 DATHRGVRSWHVGVPALLGAVSIPMALYMNTPAATVAAITVTACAIFSALPTFWSIPGRF 368 + R R H VP + A++ A ++ PA +A ++++ +++ FW++P F Sbjct: 321 RSDLRAERRLHSAVPLGVAALAFVGAGFIGHPAVAMAMLSLSLAGLYAFKSPFWALPTLF 380 Query: 369 LSGAAAAAGIALINTVGNAAGFIAPFVTGAIKDATGS 405 L+ + AA IA+IN+VGN GF+ PF G K S Sbjct: 381 LTRSTAAVSIAVINSVGNLGGFVGPFAIGYFKGQMHS 417 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 298 bits (764), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 174/428 (40%), Positives = 266/428 (62%), Gaps = 11/428 (2%) Query: 4 ATSAVEKSAIRKVSLRLVPFVALMFFINFLDRTAISFAGPNGMTKDLALTAAQFGFAAGV 63 + S E++ RKVS RL+PF+ L + + +LDR + FA M DL + +G AG+ Sbjct: 19 SASGFEEATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQ-MLNDLKFSETVYGLGAGI 77 Query: 64 FFIGYVLLEIPSNLALHKYGARRWLARIMVTWGIVALLFTWVSNVEGLYVLRFLLGVAEA 123 FFIGY L E+PSN+ LH+ GAR W+ARIM++WG+++ +V+ YV+RFLLG+AEA Sbjct: 78 FFIGYFLFEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFYVMRFLLGLAEA 137 Query: 124 GFFPGAILFLSMWVPARHRSHILALFYLAQPLTIVIGAPVAALLIEAH-GLFGLEGWRVM 182 GFFPG IL+L+ W PA R F A L+ VIG P++ ++ G++GL GW+ M Sbjct: 138 GFFPGIILYLTYWYPAERRGRTTTFFMTAVALSGVIGGPISGWALKTFGGVYGLAGWQWM 197 Query: 183 FAGVAIPAIVVGVIAWFYLADKPADAKWLNEAERNWLTAALASENKTKRITAQSNVTSAL 242 F IP++V+G+ YL ++ + A+WL + E+ LT +A+E K + + + + Sbjct: 198 FLIEGIPSVVIGLCVLAYLDNRISHARWLTDEEKALLTRNIAAEEAQKE---DAPIAAIM 254 Query: 243 TNSRVWLLSLVYFGLIYGLYALAFFLPTIIGGFEAQFGSKFNVFQKGLITAIPYLPAAVA 302 + RVWL+SL+YF + GLY ++F+LPT+I Q G + GL+TAIPY A VA Sbjct: 255 ASPRVWLMSLIYFSFVMGLYGVSFWLPTLI----KQTGVA-DPLSVGLLTAIPYGAAVVA 309 Query: 303 LYLWSRDATHRGVRSWHVGVPALLGAVSIPM-ALYMNTPAATVAAITVTACAIFSALPTF 361 + L +R A R WH+ +PAL GA+ + + A++ +AA+T+ I + LP F Sbjct: 310 MVLVARSADRTRERRWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILTTLPLF 369 Query: 362 WSIPGRFLSGAAAAAGIALINTVGNAAGFIAPFVTGAIKDATGSYQAPMFVVGALMLMSA 421 WS+P FL+G AAAGIALIN++GN AGF++P+ G +KD T S + M+++ A M++ A Sbjct: 370 WSLPTAFLAGTGAAAGIALINSLGNLAGFLSPYAVGWLKDTTRSTDSGMYLLAASMVLGA 429 Query: 422 VVIFAIGA 429 ++ ++ A Sbjct: 430 LLTLSVPA 437 >AGc4908 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 487 Score = 297 bits (760), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 163/416 (39%), Positives = 245/416 (58%), Gaps = 8/416 (1%) Query: 9 EKSAIRKVSLRLVPFVALMFFINFLDRTAISFAGPNGMTKDLALTAAQFGFAAGVFFIGY 68 EK+ I K++ RL+PF+ L++ I ++DR +S+A M L+L+ +G A +FFIGY Sbjct: 66 EKALISKITWRLMPFLGLLYLIAYIDRQNVSYAKLQ-MVDALSLSEYAYGLGASLFFIGY 124 Query: 69 VLLEIPSNLALHKYGARRWLARIMVTWGIVALLFTWVSNVEGLYVLRFLLGVAEAGFFPG 128 L E+PSNL L+++GA +W ARI+V+WG V + + N Y+LRFLLG+ EAGFFPG Sbjct: 125 FLFEVPSNLFLNRFGASKWFARILVSWGAVTIALAYTQNATMFYILRFLLGLCEAGFFPG 184 Query: 129 AILFLSMWVPARHRSHILALFYLAQPLTIVIGAPVAALLIEAHGLFGLEGWRVMFAGVAI 188 + +++W P +R ++ LF + L +GAP+ +L++ G G GW +F I Sbjct: 185 VLFLMTLWFPRDYRGRMIGLFMIFSALANAVGAPLGGMLLDLDGFLGYAGWEWVFLATGI 244 Query: 189 PAIVVGVIAWFYLADKPADAKWLNEAERNWLTAALASENKTKRITAQSNVTSALTNSRVW 248 PA++ G++ +FYL D P AK+L + E++WL LA ENK A+ AL N RV Sbjct: 245 PAVIAGIVTFFYLDDTPDKAKFLTQDEKDWLKNRLAEENKGMEEHAEDGF-KALVNPRVL 303 Query: 249 LLSLVYFGLIYGLYALAFFLPTIIGGFEAQFGSKFNVFQKGLITAIPYLPAAVALYLWSR 308 ++L Y G Y L+++LPTI+ F + G I IP++ A+AL++ Sbjct: 304 FMALCYVGFPLAAYGLSYWLPTIVKSFGVSNTT------NGFINIIPWIIVAIALFVVPS 357 Query: 309 DATHRGVRSWHVGVPALLGAVSIPMALYMNTPAATVAAITVTACAIFSALPTFWSIPGRF 368 A ++ ++ PA +GA + M+ ++ P A + V A IF+ P FWS+PGRF Sbjct: 358 AADKAKNKTPYIVGPAFVGAFCLLMSALLSDPVLQFAFLCVAAAGIFAGQPVFWSLPGRF 417 Query: 369 LSGAAAAAGIALINTVGNAAGFIAPFVTGAIKDATGSYQAPMFVVGALMLMSAVVI 424 L GA AAAGIA IN+VGN GF+A V IKD TGS APMF + + ++ V++ Sbjct: 418 LKGAGAAAGIAAINSVGNLGGFVAQNVVPWIKDQTGSTIAPMFFLAFCLALAGVLV 473 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 296 bits (759), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 174/425 (40%), Positives = 253/425 (59%), Gaps = 11/425 (2%) Query: 9 EKSAIRKVSLRLVPFVALMFFINFLDRTAISFAGPNGMTKDLALTAAQFGFAAGVFFIGY 68 E +A RK L+P + L + +N+LDR + FA M DL + +G AG+FFIGY Sbjct: 18 ENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQ-MADDLQFSDTVYGLGAGMFFIGY 76 Query: 69 VLLEIPSNLALHKYGARRWLARIMVTWGIVALLFTWVSNVEGLYVLRFLLGVAEAGFFPG 128 LEIPSNL LH+ GAR W+ARIM+TWGI++ +V+ YV+RFLLGVAEAGFFPG Sbjct: 77 FFLEIPSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFYVMRFLLGVAEAGFFPG 136 Query: 129 AILFLSMWVPARHRSHILALFYLAQPLTIVIGAPVAALLIEA-HGLFGLEGWRVMFAGVA 187 IL++S W P+ R + LF ++ PL+ +IGAP++ +++ +G G GW+ MF Sbjct: 137 IILYISYWFPSHRRGRVYGLFVISVPLSGIIGAPLSGWIMQYFNGFQGYAGWQWMFILEG 196 Query: 188 IPAIVVGVIAWFYLADKPADAKWLNEAERNWLTAALASENKTKRITAQSNVTSALTNSRV 247 IP+++VG++ + L D+ A WL + E++ L + +E A S + A RV Sbjct: 197 IPSVLVGILIIYKLKDRITHATWLTDKEKDILQTNIENEAAHY---AHSRLRDAFLQPRV 253 Query: 248 WLLSLVYFGLIYGLYALAFFLPTIIGGFEAQFGSKFNVFQKGLITAIPYLPAAVALYLWS 307 WLL+L+YF LI G Y + F+LPT+I G K ++ G +TAIP AAV + + S Sbjct: 254 WLLTLIYFCLISGFYTIGFWLPTLI----RDSGVK-DILSIGFLTAIPSAAAAVTMIVVS 308 Query: 308 RDATHRGVRSWHVGVPALLGAVSIPMALYM-NTPAATVAAITVTACAIFSALPTFWSIPG 366 R A R WH+ + A+LGAV I ++ Y + + +T+ A S +P FWS+P Sbjct: 309 RSADRLRERRWHLALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMGALSTIPLFWSLPT 368 Query: 367 RFLSGAAAAAGIALINTVGNAAGFIAPFVTGAIKDATGSYQAPMFVVGALMLMSAVVIFA 426 FL G+AAAAGIA IN+ GN GF+AP++ G +KD T S M ++ + + A ++F Sbjct: 369 AFLGGSAAAAGIAFINSWGNLGGFVAPYMMGYLKDLTQSTTTGMLIISTTLFIGAALVFL 428 Query: 427 IGAGA 431 I A A Sbjct: 429 IPAKA 433