BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0007.p (275 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cgl2686 [GEPR] COG0477 Permeases of the major facilitator superf... 122 8e-28 YPO1267 [GEPR] COG0477 Permeases of the major facilitator superf... 121 1e-27 PA4136 [GEPR] COG0477 Permeases of the major facilitator superfa... 119 1e-26 Zbcr [GEPR] COG0477 Permeases of the major facilitator superfami... 114 2e-25 ECs3074 [GEPR] COG0477 Permeases of the major facilitator superf... 114 2e-25 >Cgl2686 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 398 Score = 122 bits (306), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 76/217 (35%), Positives = 124/217 (57%), Gaps = 6/217 (2%) Query: 23 TDLYLPALPHLAHDLGSDVPAVQATISSFMIALALSQLLWGALADKLGMRNTLLAGVALL 82 TD+YLPA+P +A DLG+ P VQ T+SSFM +A+ QL+ G L+D+LG + L+AG Sbjct: 26 TDMYLPAMPGIAEDLGTTAPMVQLTLSSFMAGMAIGQLIIGPLSDQLGRKGLLVAGAVAA 85 Query: 83 AVTGAACALATDVDALIVYRTVQGIGAGAATVVVPVLLRRRFADADAMRAISWVSIAESV 142 V CALA + L++ R VQG+G GA V+ ++ A A + + I + + Sbjct: 86 LVASVVCALAPSISVLVIARLVQGLGGGACVVIARAIVPDLERGQKAAHAFALLMIIQGI 145 Query: 143 IPAIAPVIGTGILLASGWRSNFWLVAILALA-LLPFILKLVPGKQVLH----GADETVS- 196 P +AP+IG ++ GWR FW +A++ A LL +L++ K V G +S Sbjct: 146 APVVAPLIGGVLVGPFGWRGIFWALALVNFAQLLVALLQIKESKPVEERTAAGLGGMLSN 205 Query: 197 YAVLLRNRAYLRDAAVYGLTFGALVTFVASAPHLIEQ 233 Y +L+N +L GL+FGA+ ++++++P +++ Sbjct: 206 YVFVLKNPQFLAYVFTLGLSFGAMFSYISASPFVLQN 242 >YPO1267 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 399 Score = 121 bits (304), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 67/228 (29%), Positives = 123/228 (53%), Gaps = 6/228 (2%) Query: 21 LATDLYLPALPHLAHDLGSDVPAVQATISSFMIALALSQLLWGALADKLGMRNTLLAGVA 80 LA D+YLP++P +A + G + VQ T+S++++ A+ Q+ +G +AD +G + + G Sbjct: 24 LAIDMYLPSMPIIAQEFGVESGRVQMTLSAYVLGFAIGQMFYGPMADSIGRKPVIFWGTL 83 Query: 81 LLAVTGAACALATDVDALIVYRTVQGIGAGAATVVVPVLLRRRFADADAMRAISWVSIAE 140 + A+ G ACAL V+ LI R + G+ A AA+VV+ L+R F + R +S+V + Sbjct: 84 IFALAGMACALVQSVEQLINMRFLHGLSAAAASVVINALMRDMFTKDEFSRMMSFVVLVM 143 Query: 141 SVIPAIAPVIGTGILLASGWRSNFWLVA----ILALALLPFILKLVP--GKQVLHGADET 194 ++ P +AP+IG +L+ W + FW +A + A+ + FI + +P +Q H Sbjct: 144 TIAPLLAPIIGGALLVWFSWHAIFWTMAGAALVGAVLVALFIQETLPPERRQKFHLRTTI 203 Query: 195 VSYAVLLRNRAYLRDAAVYGLTFGALVTFVASAPHLIEQWSSRGPGTF 242 ++ L R++ L G +F + +F+++ P + + P F Sbjct: 204 GNFGSLFRHKRVLSYMLASGFSFAGMFSFLSAGPFVYIDLNGVSPQNF 251 >PA4136 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 402 Score = 119 bits (297), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 78/245 (31%), Positives = 133/245 (54%), Gaps = 7/245 (2%) Query: 13 AALTGVGMLATDLYLPALPHLAHDLGSDVPAVQATISSFMIALALSQLLWGALADKLGMR 72 +AL G L+ D+YLP+LP +A DLG+ VQ +IS F++ + L +G L+D+ G R Sbjct: 22 SALVAFGPLSIDMYLPSLPAIAADLGASDAQVQRSISGFLVGFCVGMLFYGPLSDRFGRR 81 Query: 73 NTLLAGVALLAVTGAACALATDVDALIVYRTVQGIGAGAATVVVPVLLRRRFADADAMRA 132 LLAG+AL + ACALA L++ R +Q +G GAA+V+ ++R + +A R Sbjct: 82 PVLLAGIALYLFSSLACALADSAGQLVLLRVLQALGGGAASVLARAMVRDLYPLGEAARM 141 Query: 133 ISWVSIAESVIPAIAPVIGTGILLASGWRSNFWLVAILALALLPFILKLV----PGKQVL 188 ++ + + + P AP++G ++L +GWR+ F ++A+ A L + ++ P ++ Sbjct: 142 LALMHMVTMLAPLAAPLLGGYLMLWAGWRALFVVLALFAGLCLLAVWRVAESHPPERRGG 201 Query: 189 HGADETVSYAVLLRNRAYLRDAAVYGLTFGALVTFVASAPH-LIEQWSSRGP--GTFALM 245 A ++Y LL +R L GL F + ++++AP IE + R G F + Sbjct: 202 SLAQAFLAYGRLLGDRRALGYVLCMGLAFAGMFAYISAAPFVFIEHFGVRAERFGWFFGL 261 Query: 246 QVCGV 250 + GV Sbjct: 262 NILGV 266 >Zbcr [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 396 Score = 114 bits (286), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 73/228 (32%), Positives = 126/228 (55%), Gaps = 6/228 (2%) Query: 21 LATDLYLPALPHLAHDLGSDVPAVQATISSFMIALALSQLLWGALADKLGMRNTLLAGVA 80 L+ D+YLPALP ++ G + Q T+S++++ AL QL++G +AD G + +L G Sbjct: 24 LSIDMYLPALPVISAQFGVPAGSTQMTLSTYILGFALGQLIYGPMADSFGRKPVVLGGTL 83 Query: 81 LLAVTGAACALATDVDALIVYRTVQGIGAGAATVVVPVLLRRRFADADAMRAISWVSIAE 140 + A ACALA +D LIV R G+ A AA+VV+ L+R + + R +S+V + Sbjct: 84 VFAAAAVACALAQTIDQLIVMRFFHGLAAAAASVVINALMRDIYPKEEFSRMMSFVMLVT 143 Query: 141 SVIPAIAPVIGTGILLASGWRSNFWLV---AILALALLPFILK--LVPG-KQVLHGADET 194 ++ P +AP++G +L+ W FW++ AILA A++ F++K L P +Q H Sbjct: 144 TIAPLMAPIVGGWVLVWLSWHYIFWILAVAAILASAMIFFLIKETLPPERRQPFHIRTTI 203 Query: 195 VSYAVLLRNRAYLRDAAVYGLTFGALVTFVASAPHLIEQWSSRGPGTF 242 ++A L R++ L G +F + +F+++ P + + + P F Sbjct: 204 GNFAALFRHKRVLSYMLASGFSFAGMFSFLSAGPFVYIEINHVAPENF 251 >ECs3074 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 396 Score = 114 bits (286), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 73/228 (32%), Positives = 126/228 (55%), Gaps = 6/228 (2%) Query: 21 LATDLYLPALPHLAHDLGSDVPAVQATISSFMIALALSQLLWGALADKLGMRNTLLAGVA 80 L+ D+YLPALP ++ G + Q T+S++++ AL QL++G +AD G + +L G Sbjct: 24 LSIDMYLPALPVISAQFGVPAGSTQMTLSTYILGFALGQLIYGPMADSFGRKPVVLGGTL 83 Query: 81 LLAVTGAACALATDVDALIVYRTVQGIGAGAATVVVPVLLRRRFADADAMRAISWVSIAE 140 + A ACALA +D LIV R G+ A AA+VV+ L+R + + R +S+V + Sbjct: 84 VFAAAAVACALAQTIDQLIVMRFFHGLAAAAASVVINALMRDIYPKEEFSRMMSFVMLVT 143 Query: 141 SVIPAIAPVIGTGILLASGWRSNFWLV---AILALALLPFILK--LVPG-KQVLHGADET 194 ++ P +AP++G +L+ W FW++ AILA A++ F++K L P +Q H Sbjct: 144 TIAPLMAPIVGGWVLVWLSWHYIFWILAVAAILASAMIFFLIKETLPPERRQPFHIRTTI 203 Query: 195 VSYAVLLRNRAYLRDAAVYGLTFGALVTFVASAPHLIEQWSSRGPGTF 242 ++A L R++ L G +F + +F+++ P + + + P F Sbjct: 204 GNFAALFRHKRVLSYMLASGFSFAGMFSFLSAGPFVYIEINHVAPENF 251