BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0185.p (243 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGl1073 [IQR] COG1028 Dehydrogenases with different specificitie... 183 2e-46 lin0362 [IQR] COG1028 Dehydrogenases with different specificitie... 170 3e-42 SMc02041 [IQR] COG1028 Dehydrogenases with different specificiti... 162 7e-40 SMc01991 [IQR] COG1028 Dehydrogenases with different specificiti... 159 5e-39 YPO3351 [IQR] COG1028 Dehydrogenases with different specificitie... 156 4e-38 >AGl1073 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 270 Score = 183 bits (465), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 99/233 (42%), Positives = 144/233 (61%) Query: 8 RKYIVTGATSGIGEVTARLLRSCGAAVVAVGRQKDKLALLREEIACETLALDIADDGAMA 67 + I+TGA GIG A+L+ + GA VVA+ R + L L+ EI ++ +D+AD A Sbjct: 35 KSVIITGAGKGIGRACAQLMAARGAEVVAISRTQSDLDSLKSEIGGRSIRVDLADIAATR 94 Query: 68 VALQDVRGIDGLVNCSGISVLENSLALTSENFDRVMQVNARGTAMMSRHVAATMIREGRS 127 A+ + D L+N +GI+VLE+ L ++ ++ V+ +N R + + A + G Sbjct: 95 AAMAEAGPCDFLINSAGINVLESVLDMSDAGYEAVLGINLRAALVTCQEFARGRVANGGG 154 Query: 128 GSIVNVSSQAALIALDDHLAYCASKAAMDAITRVMCAELGPHGIRVNSVNPTVTLTPMAL 187 G+IVN++S A DHL Y ASKA ++ TRV+ ELGPHGIRVN+V PT+TLT +A Sbjct: 155 GAIVNITSIAGHRGFQDHLCYAASKAGLEGATRVLAKELGPHGIRVNAVAPTITLTELAA 214 Query: 188 QAWADPEKRRRILEAIPLRKFAAPEDVAAPILFLLSDAAAMISGVSLPIDGGY 240 +AW DPEK + ++ PL +FA E+VA I LLSD + MISG LP+DGG+ Sbjct: 215 EAWNDPEKSQPMMVRHPLNRFAEAEEVAQSIALLLSDDSKMISGAVLPVDGGF 267 >lin0362 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Lin Listeria innocua Length = 254 Score = 170 bits (431), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 99/247 (40%), Positives = 155/247 (62%), Gaps = 12/247 (4%) Query: 3 FDVAKRKYIVTGATSGIGEVTARLLRSCGAAVVAVGRQKDKLALLREEIACETLAL--DI 60 F++ + +VTGA SGIG+ A L GA VV + ++D + + TLAL DI Sbjct: 10 FNITDKVAVVTGAASGIGKAMAELFSEKGAYVVLLDIKEDVKDVAAQINPSRTLALQVDI 69 Query: 61 ADDGAMAVALQDVRG----IDGLVNCSGISVLENSLALTSENFDRVMQVNARGTAMMSRH 116 + + +++ ID L N +G+++LE + L E +D+ M++N +G+ +M++ Sbjct: 70 TKKENIEKVVAEIKKVYPKIDILANSAGVALLEKAEDLPEEYWDKTMELNLKGSFLMAQI 129 Query: 117 VAATMIREGRSGSIVNVSSQAALIALDDHLAYCASKAAMDAITRVMCAELGPHGIRVNSV 176 + MI G G IVN++SQA++IALD H+AYCASKAA+ ++T+V+ E P+ I VN++ Sbjct: 130 IGREMIATG-GGKIVNMASQASVIALDKHVAYCASKAAIVSMTQVLAMEWAPYNINVNAI 188 Query: 177 NPTVTLTPMALQAWADP--EKRRRILEAIPLRKFAAPEDVAAPILFLLSDAAAMISGVSL 234 +PTV LT + +AWA E +++ IP +F PE+VAA LFL+SDAA++I+G +L Sbjct: 189 SPTVILTELGKKAWAGQVGEDMKKL---IPAGRFGYPEEVAACALFLVSDAASLITGENL 245 Query: 235 PIDGGYT 241 IDGGYT Sbjct: 246 IIDGGYT 252 >SMc02041 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 254 Score = 162 bits (409), Expect = 7e-40, Method: Compositional matrix adjust. Identities = 97/255 (38%), Positives = 146/255 (57%), Gaps = 27/255 (10%) Query: 2 LFDVAKRKYIVTGATSGIGEVTARLLRSCGAAVVAVGRQKDKLALLREEIACETLAL--- 58 L D + + +VTGA +GIG A A ++ ++ALL + A +A+ Sbjct: 10 LLDFSGKTVVVTGAATGIGRAVAE----------AFATKRARVALLDRDAAVSDVAVSLG 59 Query: 59 --------DIADDGAMAVALQDVRG----IDGLVNCSGISVLENSLALTSENFDRVMQVN 106 D+ D+ + A++ V ID L+N +GI L + + + +DR + VN Sbjct: 60 TGHIAHVADVTDEQGVERAVKSVTEAFGRIDILINNAGIGPLAPAESYPTAEWDRTLAVN 119 Query: 107 ARGTAMMSRHVAATMIREGRSGSIVNVSSQAALIALDDHLAYCASKAAMDAITRVMCAEL 166 +G +M+R +A M+ +G SG IVN++SQAA+I ++ H+AYCASKA + +T M E Sbjct: 120 LKGAFLMARAIAPGMLEQG-SGRIVNMASQAAIIGIEGHVAYCASKAGIIGMTNCMALEW 178 Query: 167 GPHGIRVNSVNPTVTLTPMALQAWADPEKRRRILEAIPLRKFAAPEDVAAPILFLLSDAA 226 GP G+ VN+V+PTV T + L WA EK R AIP R+FA P ++AA +L+L AA Sbjct: 179 GPRGVTVNAVSPTVVETELGLTGWAG-EKGERARAAIPTRRFAKPWEIAASVLYLAGGAA 237 Query: 227 AMISGVSLPIDGGYT 241 AM++G +L IDGGYT Sbjct: 238 AMVNGANLMIDGGYT 252 >SMc01991 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 241 Score = 159 bits (402), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 96/238 (40%), Positives = 138/238 (57%) Query: 3 FDVAKRKYIVTGATSGIGEVTARLLRSCGAAVVAVGRQKDKLALLREEIACETLALDIAD 62 + + + IVTG GIG T LL + GA VVA+ R + L L + C + D+AD Sbjct: 1 MEFSGKSVIVTGGGKGIGRATVALLAARGAQVVALSRTQSDLDELSSQTGCHGIVADLAD 60 Query: 63 DGAMAVALQDVRGIDGLVNCSGISVLENSLALTSENFDRVMQVNARGTAMMSRHVAATMI 122 A A+ + D LVNC+G +VLE+ + +T + +D VM N R + ++ A + Sbjct: 61 AAAARAAMVEAGTCDILVNCAGTNVLESLIDMTDDGYDVVMNTNLRAALICAQEFARARM 120 Query: 123 REGRSGSIVNVSSQAALIALDDHLAYCASKAAMDAITRVMCAELGPHGIRVNSVNPTVTL 182 G G+IVNV+S A +H+ Y ASKA ++ TRVM ELGP+GIRV ++ PT+T+ Sbjct: 121 AAGGGGAIVNVTSIAGHRGFQNHVCYAASKAGLEGATRVMAKELGPYGIRVVAIAPTITM 180 Query: 183 TPMALQAWADPEKRRRILEAIPLRKFAAPEDVAAPILFLLSDAAAMISGVSLPIDGGY 240 T +A AWADP+K ++ P +FA +DVA I LLS A M+SG LP+DGG+ Sbjct: 181 TELAAAAWADPQKSEPMMVRHPAGRFATVDDVARSIAMLLSSDAEMVSGAVLPVDGGF 238 >YPO3351 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ype Yersinia pestis Length = 256 Score = 156 bits (395), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 97/248 (39%), Positives = 148/248 (59%), Gaps = 10/248 (4%) Query: 3 FDVAKRKYIVTGATSGIGEVTARLLRSCGAAVVAVGRQKDKLALLREEIACET---LALD 59 F ++ + +TG +GIG A L + GA VV + D +A + E++ + L D Sbjct: 12 FSLSGKVAAITGGATGIGHAIAELYLAKGARVVLM-DCADNVAEIAEQLDRDNAVGLHCD 70 Query: 60 IADDG----AMAVALQDVRGIDGLVNCSGISVLENSLALTSENFDRVMQVNARGTAMMSR 115 ++D A+A A+ +D LVN +GI+ L+ + + +++DR + +N +G +M + Sbjct: 71 VSDSQSVRQAVAQAIGAFGQLDILVNSAGIAALDPAEKVREQDWDRTIDINLKGVFLMCQ 130 Query: 116 HVAATMIREGRSGSIVNVSSQAALIALDDHLAYCASKAAMDAITRVMCAELGPHGIRVNS 175 V I+ G G IVN++SQA ++AL +HLAYCASK + IT+V+ E GP I+VN+ Sbjct: 131 EVGKHFIQHGH-GKIVNLASQAGVVALPNHLAYCASKFGVIGITKVLALEWGPLDIQVNA 189 Query: 176 VNPTVTLTPMALQAWADPEKRRRILEAIPLRKFAAPEDVAAPILFLLSDAAAMISGVSLP 235 ++PTV LT + +AW+ L+ IP R+FA P +VAA LFL SDAA MI+G +L Sbjct: 190 ISPTVVLTALGQKAWSGQLAEDMKLK-IPARRFAYPAEVAACALFLASDAANMITGENLV 248 Query: 236 IDGGYTSQ 243 IDGGYT Q Sbjct: 249 IDGGYTIQ 256