BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0181.p (432 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3328 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved... 665 0.0 NMA0074 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved... 586 e-167 NMB0193 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved... 585 e-167 PA5565 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved ... 575 e-164 ZgidA [D] COG0445 NAD/FAD-utilizing enzyme apparently involved i... 560 e-159 >RSc3328 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division Rso Ralstonia solanacearum Length = 647 Score = 665 bits (1717), Expect = 0.0, Method: Compositional matrix adjust. Identities = 318/424 (75%), Positives = 366/424 (86%), Gaps = 7/424 (1%) Query: 1 VLEEQPGDLDPIPVFSVMGNVGMHPQQMPCWITHTNTQTHDIIRAGLDRSPMYTGVIEGV 60 VLE QPGDLDP+PVFS +G MHP+Q+PCW+THTN +THDIIRAGL+RSPMYTGVIEGV Sbjct: 214 VLEAQPGDLDPVPVFSFLGRTDMHPRQVPCWVTHTNERTHDIIRAGLNRSPMYTGVIEGV 273 Query: 61 GPRYCPSIEDKIHRFAGKDSHQIYLEPEGLTTNEFYPNGISTSLPFDVQLALVRSMRGME 120 GPRYCPSIEDKIHRFA KDSHQI+LEPEGLTTNEFYPNG+STSLPFDVQL L+ SMRG+E Sbjct: 274 GPRYCPSIEDKIHRFASKDSHQIFLEPEGLTTNEFYPNGVSTSLPFDVQLDLIHSMRGLE 333 Query: 121 NAHILRPGYAIEYDYFDPRGLKSSLETRQIQGLFFAGQINGTTGYEEAAAQGMLAGLNAA 180 +AHILRPGYAIEYDYFDPRGLK+SLE++ I GLFFAGQINGTTGYEEAAAQG+LAG+NA Sbjct: 334 HAHILRPGYAIEYDYFDPRGLKASLESKAIGGLFFAGQINGTTGYEEAAAQGLLAGINAG 393 Query: 181 LQTQGRDSWTPRRDEAYLGVLVDDLITQGVLEPYRMFTSRAEYRLSLREDNADLRLTEIG 240 LQ QG+ +WTPRRD+AYLGVLVDDLIT+GV EPYRMFTSRAE+RLSLREDNAD+RLTE G Sbjct: 394 LQVQGKAAWTPRRDQAYLGVLVDDLITRGVTEPYRMFTSRAEFRLSLREDNADMRLTEAG 453 Query: 241 RQLGCVGDAQWEMFEKKREAVAREMERLKSTWVNPRILAEAEAERVLGKAIDHEYSLFDL 300 R LG V DA+W+ F +KR+AV+RE ERLKSTWVNP IL A+AE VLGK I+ EYSL DL Sbjct: 454 RDLGVVDDARWDAFNRKRDAVSRETERLKSTWVNPAILPAADAEPVLGKGIEREYSLADL 513 Query: 301 LRRPNVTYDSLMTLAGADGQALAGPGVSDDP-----VREQIEIQIKYAGYIDRQAKEIGR 355 LRRPNVTY+SLM + G G+ ++D+P +REQIEI IKY GYI RQA E+ R Sbjct: 514 LRRPNVTYESLMGMQG--GKYAPDAPLADEPLLAEQIREQIEIGIKYHGYIARQADEVER 571 Query: 356 QEHNESLKLPADLDYMEVQALSIEVRQKLNKHKPETLGQASRISGVTPAALSLLLVHLKK 415 NE+ +LPAD DY +V+ LSIEV+QKL +HKPET+GQASRISG+TPAA+SLLLVHLKK Sbjct: 572 LGANENTRLPADFDYKQVRGLSIEVQQKLAQHKPETIGQASRISGITPAAVSLLLVHLKK 631 Query: 416 GGLK 419 G L+ Sbjct: 632 GVLR 635 >NMA0074 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division NmA Neisseria meningitidis Z2491 Length = 628 Score = 586 bits (1510), Expect = e-167, Method: Compositional matrix adjust. Identities = 293/415 (70%), Positives = 346/415 (83%), Gaps = 6/415 (1%) Query: 2 LEEQPGDLDPIPVFSVMGNVGMHPQQMPCWITHTNTQTHDIIRAGLDRSPMYTGVIEGVG 61 L EQPGD P+PV SV GN MHP+Q+ CWITHTNTQTHDIIR+G DRSPM+TG IEGVG Sbjct: 215 LTEQPGD-TPVPVMSVRGNAEMHPRQVSCWITHTNTQTHDIIRSGFDRSPMFTGKIEGVG 273 Query: 62 PRYCPSIEDKIHRFAGKDSHQIYLEPEGLTTNEFYPNGISTSLPFDVQLALVRSMRGMEN 121 PRYCPSIEDKI+RFA KDSHQI+LEPEGLTT E+YPNGISTSLPFD+Q+ALVRSM+G+EN Sbjct: 274 PRYCPSIEDKINRFADKDSHQIFLEPEGLTTYEYYPNGISTSLPFDIQIALVRSMKGLEN 333 Query: 122 AHILRPGYAIEYDYFDPRGLKSSLETRQIQGLFFAGQINGTTGYEEAAAQGMLAGLNAAL 181 AHILRPGYAIEYDYFDPR LK+SLET+ I+GLFFAGQINGTTGYEEAAAQG+LAG NA Sbjct: 334 AHILRPGYAIEYDYFDPRNLKASLETKTIEGLFFAGQINGTTGYEEAAAQGLLAGANAVQ 393 Query: 182 QTQGRDSWTPRRDEAYLGVLVDDLITQGVLEPYRMFTSRAEYRLSLREDNADLRLTEIGR 241 +G+D RR++AYLGVLVDDLIT+GV EPYRMFTSRAEYRL LREDNAD+RLTE G Sbjct: 394 YVRGQDPLLLRREQAYLGVLVDDLITKGVNEPYRMFTSRAEYRLQLREDNADMRLTEDGY 453 Query: 242 QLGCVGDAQWEMFEKKREAVAREMERLKSTWVNPRILAEAEAERVLGKAIDHEYSLFDLL 301 ++G VG+AQW MF +KREAV RE++RLK+TW P+ LAE E RV G+ + E +L DLL Sbjct: 454 KIGLVGEAQWRMFNEKREAVEREIQRLKTTWYTPQKLAEDEQIRVFGQKLSREANLHDLL 513 Query: 302 RRPNVTYDSLMTLAGADGQALAGPGVSDDPVREQIEIQIKYAGYIDRQAKEIGRQEHNES 361 RRPN+ Y +LMTL G A+ +S + V EQ+EIQ+KY GYIDRQ +EI + E+ Sbjct: 514 RRPNLDYAALMTLEG----AMPSENLSAE-VIEQVEIQVKYQGYIDRQNEEIDSRRDIET 568 Query: 362 LKLPADLDYMEVQALSIEVRQKLNKHKPETLGQASRISGVTPAALSLLLVHLKKG 416 LKLP +DY +V+ LS EV+QKLN+HKPET+GQASRISGVTPAA++LL+VHLK+G Sbjct: 569 LKLPDGIDYGKVKGLSAEVQQKLNQHKPETVGQASRISGVTPAAVALLMVHLKRG 623 >NMB0193 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division Nme Neisseria meningitidis MC58 Length = 631 Score = 585 bits (1508), Expect = e-167, Method: Compositional matrix adjust. Identities = 292/415 (70%), Positives = 345/415 (83%), Gaps = 6/415 (1%) Query: 2 LEEQPGDLDPIPVFSVMGNVGMHPQQMPCWITHTNTQTHDIIRAGLDRSPMYTGVIEGVG 61 L EQPGD P+PV SV GN MHP+Q+ CWITHTNTQTHDIIR+G DRSPM+TG IEGVG Sbjct: 218 LTEQPGD-TPVPVMSVRGNADMHPRQVSCWITHTNTQTHDIIRSGFDRSPMFTGKIEGVG 276 Query: 62 PRYCPSIEDKIHRFAGKDSHQIYLEPEGLTTNEFYPNGISTSLPFDVQLALVRSMRGMEN 121 PRYCPSIEDKI+RFA KDSHQI+LEPEGLTT+E+YPNGISTSLPFD+Q+ALVRSM+G+EN Sbjct: 277 PRYCPSIEDKINRFADKDSHQIFLEPEGLTTHEYYPNGISTSLPFDIQIALVRSMKGLEN 336 Query: 122 AHILRPGYAIEYDYFDPRGLKSSLETRQIQGLFFAGQINGTTGYEEAAAQGMLAGLNAAL 181 AHILRPGYAIEYDYFDPR LK+SLET+ I GLFFAGQINGTTGYEEAAAQG+LAG NA Sbjct: 337 AHILRPGYAIEYDYFDPRNLKASLETKTIAGLFFAGQINGTTGYEEAAAQGLLAGANAVQ 396 Query: 182 QTQGRDSWTPRRDEAYLGVLVDDLITQGVLEPYRMFTSRAEYRLSLREDNADLRLTEIGR 241 +G+D RR++AYLGVLVDDLIT+GV EPYRMFTSRAEYRL LREDNAD+RLTE G Sbjct: 397 YVRGQDPLLLRREQAYLGVLVDDLITKGVNEPYRMFTSRAEYRLQLREDNADMRLTEDGY 456 Query: 242 QLGCVGDAQWEMFEKKREAVAREMERLKSTWVNPRILAEAEAERVLGKAIDHEYSLFDLL 301 ++G V +AQW MF +KREAV RE++RLK+TW P+ LAE E RV G+ + E +L DLL Sbjct: 457 KIGLVSEAQWRMFNEKREAVEREIQRLKTTWYTPQKLAEGEQIRVFGQKLSREANLHDLL 516 Query: 302 RRPNVTYDSLMTLAGADGQALAGPGVSDDPVREQIEIQIKYAGYIDRQAKEIGRQEHNES 361 RRPN+ Y +LMTL G A+ +S + V EQ+EIQ+KY GYIDRQ +EI + E+ Sbjct: 517 RRPNLDYAALMTLEG----AMPSENLSAE-VIEQVEIQVKYQGYIDRQNEEIDSRRDIET 571 Query: 362 LKLPADLDYMEVQALSIEVRQKLNKHKPETLGQASRISGVTPAALSLLLVHLKKG 416 LKLP +DY +V+ LS EV+QKLN+HKPET+GQASRISGVTPAA++LL+VHLK+G Sbjct: 572 LKLPDGIDYGKVKGLSAEVQQKLNQHKPETVGQASRISGVTPAAVALLMVHLKRG 626 >PA5565 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division Pae Pseudomonas aeruginosa Length = 630 Score = 575 bits (1483), Expect = e-164, Method: Compositional matrix adjust. Identities = 283/427 (66%), Positives = 333/427 (77%), Gaps = 11/427 (2%) Query: 1 VLEEQPGDLDPIPVFSVMGNVGMHPQQMPCWITHTNTQTHDIIRAGLDRSPMYTGVIEGV 60 V+ EQPGD PIPV S +G+ HP+Q+ CWITHTN +TH+II A LDRSPMY+GVIEG+ Sbjct: 214 VMTEQPGD-TPIPVMSFLGSKEQHPEQVSCWITHTNARTHEIIAANLDRSPMYSGVIEGI 272 Query: 61 GPRYCPSIEDKIHRFAGKDSHQIYLEPEGLTTNEFYPNGISTSLPFDVQLALVRSMRGME 120 GPRYCPSIEDKIHRFA K+SHQ++LEPEGLTT+E YPNGISTSLPFDVQL +VRS+RGME Sbjct: 273 GPRYCPSIEDKIHRFADKESHQVFLEPEGLTTHELYPNGISTSLPFDVQLQIVRSIRGME 332 Query: 121 NAHILRPGYAIEYDYFDPRGLKSSLETRQIQGLFFAGQINGTTGYEEAAAQGMLAGLNAA 180 NAHI+RPGYAIEYD+FDPR L+ SLET+ I GLFFAGQINGTTGYEEA AQG+LAG NAA Sbjct: 333 NAHIVRPGYAIEYDFFDPRDLRYSLETKVIGGLFFAGQINGTTGYEEAGAQGLLAGANAA 392 Query: 181 LQTQGRDSWTPRRDEAYLGVLVDDLITQGVLEPYRMFTSRAEYRLSLREDNADLRLTEIG 240 L++QG+DSW PRRDEAY+GVLVDDLIT G EPYRMFTSRAEYRL LREDNADLRLTE G Sbjct: 393 LRSQGKDSWCPRRDEAYIGVLVDDLITLGTQEPYRMFTSRAEYRLILREDNADLRLTEKG 452 Query: 241 RQLGCVGDAQWEMFEKKREAVAREMERLKSTWVNPRI-LAEAEAERVLGKAIDHEYSLFD 299 R+LG V D +W FE KRE + RE +RLKSTWV P +A AER G + HEY+L + Sbjct: 453 RELGLVDDRRWAAFEAKREGIEREEQRLKSTWVRPNTPQGDAIAER-FGTPLTHEYNLLN 511 Query: 300 LLRRPNVTYDSLMTLAGADGQALAGPGVSDDPVREQIEIQIKYAGYIDRQAKEIGRQEHN 359 LL RP + Y L+ + G V + V EQ+EI+ KYAGYIDRQ +EI R + Sbjct: 512 LLSRPEIDYAGLVEITGN--------AVDNPQVAEQVEIRTKYAGYIDRQQEEISRLRAS 563 Query: 360 ESLKLPADLDYMEVQALSIEVRQKLNKHKPETLGQASRISGVTPAALSLLLVHLKKGGLK 419 E +LP D+DY+ + LS E++ KLN+ +PETLGQASRI GVTPAA+SLLL+HLKK Sbjct: 564 EDTRLPVDIDYLGISGLSKEIQNKLNQARPETLGQASRIPGVTPAAISLLLIHLKKRASG 623 Query: 420 NVAEASA 426 E SA Sbjct: 624 RQLEQSA 630 >ZgidA [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division EcZ Escherichia coli O157:H7 EDL933 Length = 629 Score = 560 bits (1443), Expect = e-159, Method: Compositional matrix adjust. Identities = 275/418 (65%), Positives = 322/418 (77%), Gaps = 7/418 (1%) Query: 1 VLEEQPGDLDPIPVFSVMGNVGMHPQQMPCWITHTNTQTHDIIRAGLDRSPMYTGVIEGV 60 VL +Q GD +P+PVFS MGN HPQQ+PC+ITHTN +THD+IR+ LDRSPMY GVIEGV Sbjct: 214 VLAQQHGD-NPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGV 272 Query: 61 GPRYCPSIEDKIHRFAGKDSHQIYLEPEGLTTNEFYPNGISTSLPFDVQLALVRSMRGME 120 GPRYCPSIEDK+ RFA ++ HQI+LEPEGLT+NE YPNGISTSLPFDVQ+ +VRSM+GME Sbjct: 273 GPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGME 332 Query: 121 NAHILRPGYAIEYDYFDPRGLKSSLETRQIQGLFFAGQINGTTGYEEAAAQGMLAGLNAA 180 NA I+RPGYAIEYD+FDPR LK +LE++ IQGLFFAGQINGTTGYEEAAAQG+LAGLNAA Sbjct: 333 NAKIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAA 392 Query: 181 LQTQGRDSWTPRRDEAYLGVLVDDLITQGVLEPYRMFTSRAEYRLSLREDNADLRLTEIG 240 + ++ W P R +AYLGVLVDDL T G EPYRMFTSRAEYRL LREDNADLRLTEIG Sbjct: 393 RLSDDKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEIG 452 Query: 241 RQLGCVGDAQWEMFEKKREAVAREMERLKSTWVNPRILAEAEAERVLGKAIDHEYSLFDL 300 R+LG V D +W F +K E + RE +RLKSTWV P A AE L + E S DL Sbjct: 453 RELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREASGEDL 512 Query: 301 LRRPNVTYDSLMTLAGADGQALAGPGVSDDPVREQIEIQIKYAGYIDRQAKEIGRQEHNE 360 LRRP +TY+ L TL P ++D+ EQ+EIQ+KY GYI RQ EI +Q NE Sbjct: 513 LRRPEMTYEKLTTLTP------FAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNE 566 Query: 361 SLKLPADLDYMEVQALSIEVRQKLNKHKPETLGQASRISGVTPAALSLLLVHLKKGGL 418 + LPA LDY +V LS EV KLN HKP ++GQASRISGVTPAA+S+LLV LKK G+ Sbjct: 567 NTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGM 624