BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0132.p (518 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2665 [KT] COG3604 Transcriptional regulator containing GAF, AA... 665 0.0 RSp0959 [KT] COG3604 Transcriptional regulator containing GAF, A... 446 e-125 VCA0182 [KT] COG3604 Transcriptional regulator containing GAF, A... 441 e-123 STM2839 [KT] COG3604 Transcriptional regulator containing GAF, A... 439 e-122 ygaA [KT] COG3604 Transcriptional regulator containing GAF, AAA-... 432 e-121 >PA2665 [KT] COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Pae Pseudomonas aeruginosa Length = 517 Score = 665 bits (1715), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/520 (65%), Positives = 402/520 (77%), Gaps = 10/520 (1%) Query: 1 MLDALIPLMADLSRELHDSERYRRLLDTLRMLFPCDAAALLRLDGEILVPLAINGLSSDT 60 +L LIPL+ADLSR+L + ERYRRLL LR L PCDA ALLRLDGE L+PLA++GLS DT Sbjct: 6 LLATLIPLVADLSRDLPEDERYRRLLQALRDLLPCDATALLRLDGEYLIPLAVDGLSPDT 65 Query: 61 LGRRFRVSEHPRFRVLLSNVPPTRFPANSSLPDPYDGLVEAHSGELHVHDCMGCQISMNG 120 LGRRFRV EHPR LL PTRFPA+ LPDPYDGLVE G L +HDC+GC + ++ Sbjct: 66 LGRRFRVGEHPRLEALLERRGPTRFPADCGLPDPYDGLVEGLHGHLEIHDCLGCPLYLDD 125 Query: 121 RPWGLLTLDALGPGRFDSVDTASLQAFASLAAATVNVAERIHNLAETSEQERQRAEAYRL 180 +PWGLLTLD L P RF S D +L+AFASLAAATV +ER+ +L +E E QRAEAY Sbjct: 126 QPWGLLTLDTLDPSRFASADLDTLEAFASLAAATVKASERMRDLTRRAEDEHQRAEAYLE 185 Query: 181 AANQSRRELIGQSPAHKRMMKEVRLAGPSNMTVLITGETGTGKELVANAIHAASPRARKP 240 AA + RE+IGQS AHK +++E+RL S+++VLITGETG GKELVA +IH S R+ KP Sbjct: 186 AAGERPREMIGQSAAHKALLEEIRLVANSDLSVLITGETGVGKELVAQSIHRHSMRSGKP 245 Query: 241 IISLNCAALPETLVESELFGHVRGAFSGAVSDRRGKFELADGGTLFLDEVGELSLTVQAK 300 +ISLNCAALPETLVESELFGHVRGAFSGAV++RRGKFELADGG+LFLDEVGEL L VQAK Sbjct: 246 MISLNCAALPETLVESELFGHVRGAFSGAVNERRGKFELADGGSLFLDEVGELPLAVQAK 305 Query: 301 LLRALQSGQIQRVGSDEEHKVDVRVIAATNRDLEEEVRLGRYRSDFYHRLSVYPLAVPPL 360 LLR LQSGQ+QRVGSD EH+VDVR+IAATNRDL EEVR GR+R+D YHRLSVYPL VPPL Sbjct: 306 LLRVLQSGQLQRVGSDREHRVDVRLIAATNRDLAEEVRAGRFRADLYHRLSVYPLRVPPL 365 Query: 361 RERGHDILLISGFFLEENRFRLGLLSLRLATDAQEVLLNYRWPGNVRELEHVIARTALKA 420 RERG DILL++G+FLEENR RLGL SLRL +AQ LL+YRWPGNVRELEH++ R +LKA Sbjct: 366 RERGRDILLLAGYFLEENRPRLGLRSLRLDHEAQAALLDYRWPGNVRELEHLVGRASLKA 425 Query: 421 LGKHPERPRILTLAAEDFDLSNEKANALSSHEGLHEQQVQTELDLQNASG--LRDAVSAY 478 LG +PER RI+TL +D DL E S V +G LR A AY Sbjct: 426 LGHNPERSRIVTLHRQDLDLPAETPAPPRS--------VVEPAPAAPTTGHSLRAATDAY 477 Query: 479 ERRLVSACLARNGGNVASAARELGVDRANLNRMAKRLGLK 518 +RRL+ CLAR+ G+ ASAARELG+DRANL R+A+RL L+ Sbjct: 478 QRRLIQDCLARHQGSWASAARELGLDRANLARLARRLQLR 517 >RSp0959 [KT] COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Rso Ralstonia solanacearum Length = 510 Score = 446 bits (1148), Expect = e-125, Method: Compositional matrix adjust. Identities = 256/500 (51%), Positives = 330/500 (66%), Gaps = 10/500 (2%) Query: 21 RYRRLLDTLRMLFPCDAAALLRLDGEILVPLAINGLSSDTLGRRFRVSEHPRFRVLLSNV 80 R +RL+ +LR F C A ALLRL+ + L P+A++GL D LGRRF V +HPR +L+ Sbjct: 19 RMQRLVGSLRSHFRCGAVALLRLEEDHLRPIAVDGLVRDALGRRFVVGQHPRLAAILARR 78 Query: 81 PPTRFPANSSLPDPYDGLVEAHSG-ELHVHDCMGCQISMNGRPWGLLTLDALGPGRFDSV 139 T F +S+LPDPYDGL++ +G L VHDCMG + + G+ WG LTLD L G FD+ Sbjct: 79 GVTCFHHDSTLPDPYDGLIDEQAGAPLPVHDCMGVSLHVEGQLWGALTLDTLKIGTFDAD 138 Query: 140 DTASLQAFASLAAATVNVAERIHNL-AETSEQERQRAEAYRLAANQSRRELIGQSPAHKR 198 A L+ A + A R L AE R + E+IGQSPA + Sbjct: 139 AQAELRQLA----VVIEAAARTTRLEAEIRALRATRGDLPPGDPAADDWEIIGQSPAIHQ 194 Query: 199 MMKEVRLAGPSNMTVLITGETGTGKELVANAIHAASPRARKPIISLNCAALPETLVESEL 258 ++ E+ + S + VL+ GETG GKEL A+ +H S R +P++ +NCAALPE+L ESEL Sbjct: 195 LLHELEVVADSELPVLLLGETGVGKELFAHRLHRLSRRRDRPLVHVNCAALPESLAESEL 254 Query: 259 FGHVRGAFSGAVSDRRGKFELADGGTLFLDEVGELSLTVQAKLLRALQSGQIQRVGSDEE 318 FGHV+GAFSGAV +R G+FE ADGGTLFLDEVGEL L VQAKLLRALQ+G+IQR+G+D Sbjct: 255 FGHVKGAFSGAVGERPGRFEAADGGTLFLDEVGELPLPVQAKLLRALQNGEIQRLGADHP 314 Query: 319 HKVDVRVIAATNRDLEEEVRLGRYRSDFYHRLSVYPLAVPPLRERGHDILLISGFFLEEN 378 VD RVIAATNR+L E VR G +R+D YHRLSVYP+ +PPLRERG+D+LL++G FLE N Sbjct: 315 RHVDARVIAATNRNLRERVRDGAFRADLYHRLSVYPVPIPPLRERGNDVLLLAGRFLESN 374 Query: 379 RFRLGLLSLRLATDAQEVLLNYRWPGNVRELEHVIARTALKALGKHPERPRILTLAAEDF 438 R RLGL SLRL+ A+E L Y WPGNVRELEHV++R ALK L + R I+TL Sbjct: 375 RARLGLRSLRLSPGAEEALRRYPWPGNVRELEHVVSRAALKMLSRGASRDDIVTLETGLL 434 Query: 439 DLSNEKANALSSHEGLHEQQVQTELDLQNASGLRDAVSAYERRLVSACLARNGGNVASAA 498 DL + +A A S GL + D+ LRDAV+ +RR + A LA + N A A Sbjct: 435 DL-DAQAVAPPSPAGLPP---EASPDIAPGITLRDAVADCQRRHIQAALAIHQDNWAQTA 490 Query: 499 RELGVDRANLNRMAKRLGLK 518 R LG+D +NL+++A+RLGLK Sbjct: 491 RTLGLDASNLHKLARRLGLK 510 >VCA0182 [KT] COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Vch Vibrio cholerae Length = 530 Score = 441 bits (1135), Expect = e-123, Method: Compositional matrix adjust. Identities = 247/521 (47%), Positives = 327/521 (62%), Gaps = 13/521 (2%) Query: 2 LDALIPLMADLSRELHDSERYRRLLDTLRMLFPCDAAALLRLDGEILVPLAINGLSSDTL 61 L L+ + L+ ++ ER+ RLLD +R CD L+ L + L PLA+ GL+ DTL Sbjct: 6 LSTLLEMTVGLASGANNEERFHRLLDAVRKAVICDCVVLMSLHNDTLTPLAMQGLTRDTL 65 Query: 62 GRRFRVSEHPRFRVLLSNVPPTRFPANSSLPDPYDGLVEAHSGELHVHDCMGCQISMNGR 121 GRRF VSEHPR + S P RF A+ LPDP+DGL+ +L +H CMG + + Sbjct: 66 GRRFVVSEHPRLAQICSADLPVRFAADCPLPDPFDGLLLDSEDDLPMHSCMGLPLHFGEQ 125 Query: 122 PWGLLTLDALGPGRFDSVDTASLQAFASLAAATVNVAERIHNLAETSEQERQRAEAY-RL 180 G+LTLD+L P FD + SL+ A++AAAT+ + L ++Q + R E + Sbjct: 126 LLGILTLDSLKPDAFDHLSPRSLEILAAIAAATLKMTLTFSELENQAKQTQLRLEELNQE 185 Query: 181 AANQSRRELIGQSPAHKRMMKEVRLAGPSNMTVLITGETGTGKELVANAIHAASPRARKP 240 A ++ E+IG S M ++ + PS +LI GETG GKELVA IH S R R+P Sbjct: 186 AWSRDSVEIIGNSGPMLAMKADIDVVAPSQFNILIHGETGVGKELVARTIHQRSNRKRQP 245 Query: 241 IISLNCAALPETLVESELFGHVRGAFSGAVSDRRGKFELADGGTLFLDEVGELSLTVQAK 300 ++ +NCAA+PE L+ESELFGHV+GAF+GA R GKF LADGGTLFLDE+GEL L+ Q+K Sbjct: 246 LVYVNCAAIPENLLESELFGHVKGAFTGADRARMGKFALADGGTLFLDEIGELPLSAQSK 305 Query: 301 LLRALQSGQIQRVGSDEEHKVDVRVIAATNRDLEEEVRLGRYRSDFYHRLSVYPLAVPPL 360 +LRALQ+ +IQ VG D VDVR++AATNRDL++EV GR+R+D YHRLSVYP+ VPPL Sbjct: 306 ILRALQNHEIQPVGQDRVQTVDVRILAATNRDLKKEVEAGRFRADLYHRLSVYPIYVPPL 365 Query: 361 RERGHDILLISGFFLEENRFRLGLLSLRLATDAQEVLLNYRWPGNVRELEHVIARTALKA 420 RER D+ L++G+F+E+ R +LG+ L+L D L+ Y WPGNVRELEHVI R ALKA Sbjct: 366 RERKGDLSLLAGYFVEQARRKLGITQLKLHGDVLSQLIQYPWPGNVRELEHVINRAALKA 425 Query: 421 LGKHPERPRILTLAAEDF-DLSNEKANALSSHEGLHEQQVQTELDLQNAS---GLRDAVS 476 + RP + TL ED +L +A + E Q E L GLRDA Sbjct: 426 KARQRGRP-VTTLKVEDLGELQGPRA-------AMVEPTAQDEPMLGEWIGELGLRDATD 477 Query: 477 AYERRLVSACLARNGGNVASAARELGVDRANLNRMAKRLGL 517 ++R L+S L + N A AAR L DRANL R+AKRLG+ Sbjct: 478 EFQRHLISETLTQADFNWAEAARRLQTDRANLTRLAKRLGI 518 >STM2839 [KT] COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Sty Salmonella typhimurium LT2 Length = 506 Score = 439 bits (1128), Expect = e-122, Method: Compositional matrix adjust. Identities = 246/517 (47%), Positives = 329/517 (63%), Gaps = 16/517 (3%) Query: 2 LDALIPLMADLSRELHDSERYRRLLDTLRMLFPCDAAALLRLDGEILVPLAINGLSSDTL 61 ++ L + +L R + +R++RL+ TLR + CDA+ALLR + +PLAI+GL+ D L Sbjct: 5 VEVLAGIAIELQRGIGHQDRFQRLITTLRQVLACDASALLRYESRQFIPLAIDGLAQDVL 64 Query: 62 GRRFRVSEHPRFRVLLSNVPPTRFPANSSLPDPYDGLVEAHSGELHVHDCMGCQISMNGR 121 GRRF + HPR + RFPA+S LPDPYDGL+ L VH C+G + Sbjct: 65 GRRFTLEGHPRLEAIARAGDVVRFPADSDLPDPYDGLIPGQE-SLKVHACVGLPLFAGQN 123 Query: 122 PWGLLTLDALGPGRFDSVDTASLQAFASLAAATVNVAERIHNLAETSEQERQRAEAYRLA 181 G LTLDA+ P +F+ L+ A+LAA ++ A I L E + + + Sbjct: 124 LIGALTLDAMTPEQFEVFSDEELRLVAALAAGALSNALLIEQL----ESQNMLPGSSGVF 179 Query: 182 ANQSRRELIGQSPAHKRMMKEVRLAGPSNMTVLITGETGTGKELVANAIHAASPRARKPI 241 +IG SPA ++ KE+ + S++ VLI GETGTGKELVA AIH SPRA P+ Sbjct: 180 EPIKETHMIGLSPAMTQLKKEIEIVAGSDLNVLIGGETGTGKELVAKAIHQGSPRAVNPL 239 Query: 242 ISLNCAALPETLVESELFGHVRGAFSGAVSDRRGKFELADGGTLFLDEVGELSLTVQAKL 301 + LNCAALPE++ ESELFGHV+GAF+GA+S+R GKFE+AD GTLFLDE+GELSL +QAKL Sbjct: 240 VYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKL 299 Query: 302 LRALQSGQIQRVGSDEEHKVDVRVIAATNRDLEEEVRLGRYRSDFYHRLSVYPLAVPPLR 361 LR LQ G IQRVG D +VDVRV+AATNRDL EEV GR+R+D +HRLSV+PL VPPLR Sbjct: 300 LRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLFVPPLR 359 Query: 362 ERGHDILLISGFFLEENRFRLGLLSLRLATDAQEVLLNYRWPGNVRELEHVIARTALKAL 421 ERG D++L++G+F E+ R RLGL + L+ A+ LLNY WPGNVRELEH I R + L Sbjct: 360 ERGDDVVLLAGYFCEQCRLRLGLSRVVLSPGARRHLLNYGWPGNVRELEHAIHRAVV--L 417 Query: 422 GKHPERPRILTLAAEDFDLSNEKANALSSHEGLHEQQVQTELDLQNASGLRDAVSAYERR 481 + + L A+ F LS + A + ++ L L LR++ ++R Sbjct: 418 ARATRAGDEVILEAQHFALSEDVLPAPPA---------ESFLALPTCRNLRESTENFQRE 468 Query: 482 LVSACLARNGGNVASAARELGVDRANLNRMAKRLGLK 518 ++ LA+N N A++AR L D ANL+R+AKRLGLK Sbjct: 469 MIRQALAQNNHNWAASARALETDVANLHRLAKRLGLK 505 >ygaA [KT] COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Eco Escherichia coli K12 Length = 529 Score = 432 bits (1111), Expect = e-121, Method: Compositional matrix adjust. Identities = 247/520 (47%), Positives = 327/520 (62%), Gaps = 24/520 (4%) Query: 2 LDALIPLMADLSRELHDSERYRRLLDTLRMLFPCDAAALLRLDGEILVPLAINGLSSDTL 61 +D L + +L R + +R++RL+ TLR + CDA+ALLR D +PLAI+GL+ D L Sbjct: 30 VDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVL 89 Query: 62 GRRFRVSEHPRFRVLLSNVPPTRFPANSSLPDPYDGLVEAHSGELHVHDCMGCQISMNGR 121 GRRF + HPR + RFPA+S LPDPYDGL+ L VH C+G + Sbjct: 90 GRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQES-LKVHACVGLPLFAGQN 148 Query: 122 PWGLLTLDALGPGRFDSVDTASLQAFASLAAATVNVAERIHNLAETSEQERQRAEAYRLA 181 G LTLD + P +FD L+ A+LAA ++ A I L Q +A Sbjct: 149 LIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQL---ESQNMLPGDATPFE 205 Query: 182 ANQSRRELIGQSPAHKRMMKEVRLAGPSNMTVLITGETGTGKELVANAIHAASPRARKPI 241 A + + ++IG SP ++ KE+ + S++ VLI+GETGTGKELVA AIH ASPRA P+ Sbjct: 206 AVK-QTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPL 264 Query: 242 ISLNCAALPETLVESELFGHVRGAFSGAVSDRRGKFELADGGTLFLDEVGELSLTVQAKL 301 + LNCAALPE++ ESELFGHV+GAF+GA+S+R GKFE+AD GTLFLDE+GELSL +QAKL Sbjct: 265 VYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKL 324 Query: 302 LRALQSGQIQRVGSDEEHKVDVRVIAATNRDLEEEVRLGRYRSDFYHRLSVYPLAVPPLR 361 LR LQ G IQRVG D +VDVRV+AATNRDL EEV GR+R+D +HRLSV+PL+VPPLR Sbjct: 325 LRVLQYGDIQRVGDDRCLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLR 384 Query: 362 ERGHDILLISGFFLEENRFRLGLLSLRLATDAQEVLLNYRWPGNVRELEHVIARTALKAL 421 ERG D++L++G+F E+ R R GL + L+ A+ +L +Y +PGNVRELEH I R + A Sbjct: 385 ERGDDVILLAGYFCEQCRLRQGLSRVVLSAGARNLLQHYSFPGNVRELEHAIHRAVVLAR 444 Query: 422 GKHPERPRILT---LAAEDFDLSNEKANALSSHEGLHEQQVQTELDLQNASGLRDAVSAY 478 IL A + L + A+ + QN LR+A A+ Sbjct: 445 ATRSGDEVILEAQHFAFPEVTLPTPEVAAVPVVK-------------QN---LREATEAF 488 Query: 479 ERRLVSACLARNGGNVASAARELGVDRANLNRMAKRLGLK 518 +R + LA+N N A+ AR L D ANL+R+AKRLGLK Sbjct: 489 QRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGLK 528