BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0080.p (334 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMa1959 [GEPR] COG0477 Permeases of the major facilitator superf... 192 1e-48 PA1352 [GEPR] COG0477 Permeases of the major facilitator superfa... 190 4e-48 YPO3263 [GEPR] COG0477 Permeases of the major facilitator superf... 166 7e-41 b2681m [GEPR] COG0477 Permeases of the major facilitator superfa... 163 4e-40 ECs3543 [GEPR] COG0477 Permeases of the major facilitator superf... 162 1e-39 >SMa1959 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 469 Score = 192 bits (487), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 129/258 (50%), Positives = 173/258 (67%), Gaps = 2/258 (0%) Query: 71 GRVVGTAQAGVVIGLLLARTLAGMIADVAGWRMVYAVSAVLALLMLALLHGRLPHRPADG 130 G VVGT +G+V+G+LLART+AG + D+AGWR VY +SA L + A+L +P +P G Sbjct: 209 GAVVGTVTSGIVLGILLARTVAGAVVDIAGWRAVYLLSAAFTLAITAILARVVPAQPKSG 268 Query: 131 GAARLSYGQLLASMATLMLHDRVLQIRGVIAMLMFAVLNIFWSALVLPLRAPPYSLSHAA 190 A +SY +L+ S+ TL L + VL++R ++A L+FA + + LVLPL APPYSLSHAA Sbjct: 269 PA--VSYPKLIGSLFTLFLQEPVLRVRAILAFLIFADVTTLLTPLVLPLSAPPYSLSHAA 326 Query: 191 IGAFGLIGVVGTLGAAKAGSWADRGRGQWTSGVALALLATAWLPLSLLSWSLWALAAGVL 250 IG FGL G G LGA++AG W D G GQ +GVAL L+ +W+ + LL +S+ L GVL Sbjct: 327 IGLFGLAGAAGALGASRAGRWTDEGFGQRVTGVALTLMLCSWILIGLLPYSILFLVTGVL 386 Query: 251 LLDLAAQAIHVTNQSMIFRASATAHSRLVACYMIFYAVGSGAGAVSSTAAFAAWGWAGVC 310 LLD QA+HV +Q +I+R A SRL A YM+FY+ GS G+ ST +A W W GV Sbjct: 387 LLDFGLQAVHVASQGLIYRVRPEAQSRLTAAYMVFYSTGSALGSSISTLVYARWAWTGVS 446 Query: 311 MLGAGVSVLGLLFWGWSL 328 MLGAG++ LLFW +L Sbjct: 447 MLGAGIAAAALLFWAITL 464 >PA1352 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 403 Score = 190 bits (482), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 152/259 (58%), Positives = 183/259 (70%), Gaps = 3/259 (1%) Query: 71 GRVVGTAQAGVVIGLLLARTLAGMIADVAGWRMVYAVSAVLALLMLALLHGRLPHRPADG 130 GRVVG AQ GVVIGLLLAR+LAG++AD+ GWR VY VSA + LL LP P++ Sbjct: 134 GRVVGAAQGGVVIGLLLARSLAGLLADLGGWRSVYLVSAASMGGLGLLLWRVLPAAPSN- 192 Query: 131 GAARLSYGQLLASMATLMLHDRVLQIRGVIAMLMFAVLNIFWSALVLPLRAPPYSLSHAA 190 L+Y QLL SM L+ RVLQ+RG++ +LMFA +FWS+LVL L APP+SLSH+A Sbjct: 193 -ELGLTYRQLLGSMFDLLASQRVLQVRGLLGLLMFAAFGVFWSSLVLLLGAPPHSLSHSA 251 Query: 191 IGAFGLIGVVGTLGAAKAGSWADRGRGQWTSGVALALLATAWLPLSLLSWSLWALAAGVL 250 IGAFGL+G +G LGAA+AGS ADRG Q SG AL LL +WLPL+L + SL AL GVL Sbjct: 252 IGAFGLVGALGALGAARAGSLADRGHAQALSGGALLLLLLSWLPLALGAHSLAALILGVL 311 Query: 251 LLDLAAQAIHVTNQSMIFRASATAHSRLVACYMIFYAVGSGAGAVSSTAAFAAWGWAGVC 310 LLDLA QAIHV NQS++F AHSRLV CYM+FYA GSG GA + TA +A GW V Sbjct: 312 LLDLAGQAIHVLNQSLVFAIDPRAHSRLVGCYMLFYAAGSGLGASAGTAMYAWAGWDAVS 371 Query: 311 MLGAGVSVLGLLFWGWSLR 329 +LGA +S+ L FW W R Sbjct: 372 LLGAAISLAALAFW-WFTR 389 >YPO3263 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 399 Score = 166 bits (420), Expect = 7e-41, Method: Compositional matrix adjust. Identities = 105/254 (41%), Positives = 156/254 (61%), Gaps = 3/254 (1%) Query: 71 GRVVGTAQAGVVIGLLLARTLAGMIADVAGWRMVYAVSAVLALLMLALLHGRLPHRPADG 130 G+VVG +G+++G+LLART+AG +A + GWR +Y V++ L +M +L LP Sbjct: 134 GKVVGIIMSGLLLGILLARTVAGALATLGGWRTIYWVASALMFIMALVLWRCLPRYKQHT 193 Query: 131 GAARLSYGQLLASMATLMLHDRVLQIRGVIAMLMFAVLNIFWSALVLPLRAPPYSLSHAA 190 G L+YGQLL S+ L +H VL+ R ++ L FA ++ W+++ L APP+ S A Sbjct: 194 G---LNYGQLLGSIFALFIHTPVLRTRALLGALSFANFSVLWTSMAFLLAAPPFGYSEAT 250 Query: 191 IGAFGLIGVVGTLGAAKAGSWADRGRGQWTSGVALALLATAWLPLSLLSWSLWALAAGVL 250 IG FGL+G G L A KAG AD+G+ + T+ L LL +WLP++ S+ AL G++ Sbjct: 251 IGLFGLVGAAGALMATKAGQLADKGKARVTTSAGLVLLLLSWLPIAFGQHSIIALIIGII 310 Query: 251 LLDLAAQAIHVTNQSMIFRASATAHSRLVACYMIFYAVGSGAGAVSSTAAFAAWGWAGVC 310 +LDLA QA+HVTNQS+++R A +RL A YM Y +G G++ S AA+ GW GV Sbjct: 311 VLDLAVQAVHVTNQSVMYRMMPEARNRLTAGYMTSYFIGGALGSLISAAAYQHAGWYGVS 370 Query: 311 MLGAGVSVLGLLFW 324 G + +L ++ W Sbjct: 371 TAGLVLCLLNIVTW 384 >b2681m [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 392 Score = 163 bits (413), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 111/265 (41%), Positives = 169/265 (63%), Gaps = 6/265 (2%) Query: 71 GRVVGTAQAGVVIGLLLARTLAGMIADVAGWRMVYAVSAVL-ALLMLALLHGRLPHRPAD 129 G+VVGT +G+++G+LLART+AG++A++ GWR V+ V++VL AL+ LAL G LP ++ Sbjct: 131 GKVVGTIMSGLLLGILLARTVAGLLANLGGWRTVFWVASVLMALMALALWRG-LPQMKSE 189 Query: 130 GGAARLSYGQLLASMATLMLHDRVLQIRGVIAMLMFAVLNIFWSALVLPLRAPPYSLSHA 189 L+Y QLL S+ ++ + D++L+ R ++ L FA +I W+++ L APP++ S Sbjct: 190 ---THLNYPQLLGSVFSMFISDKILRTRALLGCLTFANFSILWTSMAFLLAAPPFNYSDG 246 Query: 190 AIGAFGLIGVVGTLGAAKAGSWADRGRGQWTSGVALALLATAWLPLSLLSWSLWALAAGV 249 IG FGL G G LGA AG +AD+G+ T+ L LL +WL + S+ AL G+ Sbjct: 247 VIGLFGLAGAAGALGARPAGGFADKGKSHHTTTFGLLLLLLSWLAIWFGHTSVLALIIGI 306 Query: 250 LLLDLAAQAIHVTNQSMIFRASATAHSRLVACYMIFYAVGSGAGAVSSTAAFAAWGWAGV 309 L+LDL Q +H+TNQ++I+R A +RL A YM Y +G AG++ S +A+ GWAGV Sbjct: 307 LVLDLTVQGVHITNQTVIYRIHPDARNRLTAGYMTSYFIGGAAGSLISASAWQHGGWAGV 366 Query: 310 CMLGAGVSVLGLLFWGWSLRHMPRA 334 C+ GA ++++ LL W W H A Sbjct: 367 CLAGATIALVNLLVW-WRGFHRQEA 390 >ECs3543 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 394 Score = 162 bits (409), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 110/265 (41%), Positives = 169/265 (63%), Gaps = 6/265 (2%) Query: 71 GRVVGTAQAGVVIGLLLARTLAGMIADVAGWRMVYAVSAVL-ALLMLALLHGRLPHRPAD 129 G+VVGT +G+++G+LLART+AG++A++ GWR V+ V++VL AL+ LAL G LP ++ Sbjct: 133 GKVVGTIMSGLLLGILLARTVAGLLANLGGWRTVFWVASVLMALMALALWRG-LPQMKSE 191 Query: 130 GGAARLSYGQLLASMATLMLHDRVLQIRGVIAMLMFAVLNIFWSALVLPLRAPPYSLSHA 189 L+Y QLL S+ ++ + +++L+ R ++ L FA +I W+++ L APP++ S Sbjct: 192 ---THLNYPQLLGSVFSMFISNKILRTRALLGCLTFANFSILWTSMAFLLAAPPFNYSDG 248 Query: 190 AIGAFGLIGVVGTLGAAKAGSWADRGRGQWTSGVALALLATAWLPLSLLSWSLWALAAGV 249 IG FGL G G LGA AG +AD+G+ T+ L LL +WL + S+ AL G+ Sbjct: 249 VIGLFGLAGAAGALGARPAGGFADKGKSHHTTTFGLLLLLLSWLAIWFGHTSVLALIIGI 308 Query: 250 LLLDLAAQAIHVTNQSMIFRASATAHSRLVACYMIFYAVGSGAGAVSSTAAFAAWGWAGV 309 L+LDL Q +H+TNQ++I+R A +RL A YM Y +G AG++ S +A+ GWAGV Sbjct: 309 LVLDLTVQGVHITNQTVIYRIHPDARNRLTAGYMTSYFIGGAAGSLISASAWQHGGWAGV 368 Query: 310 CMLGAGVSVLGLLFWGWSLRHMPRA 334 C+ GA ++++ LL W W H A Sbjct: 369 CLAGATIALVNLLVW-WRGFHRQEA 392