BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0072.p (266 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ZyijE [GER] COG0697 Permeases of the drug/metabolite transporter... 86 7e-17 yijE [GER] COG0697 Permeases of the drug/metabolite transporter ... 86 7e-17 ECs4872 [GER] COG0697 Permeases of the drug/metabolite transport... 85 2e-16 BS_yoaV [GER] COG0697 Permeases of the drug/metabolite transport... 81 2e-15 BS_ydfC [GER] COG0697 Permeases of the drug/metabolite transport... 70 7e-12 >ZyijE [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 312 Score = 86.3 bits (212), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 81/263 (30%), Positives = 118/263 (44%), Gaps = 13/263 (4%) Query: 7 TAIRSCIGTVVLLILCLARGRLVLPQRGDLPVVFSVGLLHMTAYSILGNVGMQHVAAGRS 66 TA+R G +VL I+ L RGR + P ++ LL L + AG+ Sbjct: 53 TALRCIFGALVLFIVLLLRGRGMRPT--PFKYTLAIALLQTCGMVGLAQWALVSGGAGKV 110 Query: 67 VVLAYTTPMWVAPCARLFLGEAFTLRRAIGTVFGLFGLVLIFNPLAFDWSNHDSVLGNGL 126 +L+YT P WV A +FLGE + + FGL L+ P D+S+ S + L Sbjct: 111 AILSYTMPFWVVIFAAVFLGERLRRGQYFAILIAAFGLFLVLQPWQLDFSSMKSAM---L 167 Query: 127 ILLGAMFWAASI-----LYVRGHRWIGEPFDLLVWQALTASCVLVPCAWLFEGPPQLDLS 181 +L + W AS LY R R + L WQ L A+ V+ A L ++D Sbjct: 168 AILSGVSWGASAIVAKRLYARHPR--VDLLSLTSWQMLYAALVMSVVA-LLVPQREIDWQ 224 Query: 182 AQVIGLQLYSATFGIAIAYWAINKVNHSLPAMTTSLGLLGVPVFGIVCSSLALGETLEFS 241 V YSA A+A+ V +LPA SL L VPV G++ S LGE Sbjct: 225 PTVFWALAYSAILATALAWSLWLFVLKNLPASIASLSTLAVPVCGVLFSWWLLGENPGAV 284 Query: 242 LVASMALIIMGIAIGALPEKRAV 264 + + LI++ +A+ + +K AV Sbjct: 285 EXSGIVLIVLALALVSRKKKEAV 307 >yijE [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Eco Escherichia coli K12 Length = 312 Score = 86.3 bits (212), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 82/263 (31%), Positives = 118/263 (44%), Gaps = 13/263 (4%) Query: 7 TAIRSCIGTVVLLILCLARGRLVLPQRGDLPVVFSVGLLHMTAYSILGNVGMQHVAAGRS 66 TA+R G +VL I+ L RGR + P ++ LL L + AG+ Sbjct: 53 TALRCIFGALVLFIVLLLRGRGMRPT--PFKYTLAIALLQTCGMVGLAQWALVSGGAGKV 110 Query: 67 VVLAYTTPMWVAPCARLFLGEAFTLRRAIGTVFGLFGLVLIFNPLAFDWSNHDSVLGNGL 126 +L+YT P WV A LFLGE + + FGL L+ P D+S+ S + L Sbjct: 111 AILSYTMPFWVVIFAALFLGERLRRGQYFAILIAAFGLFLVLQPWQLDFSSMKSAM---L 167 Query: 127 ILLGAMFWAASI-----LYVRGHRWIGEPFDLLVWQALTASCVLVPCAWLFEGPPQLDLS 181 +L + W AS LY R R + L WQ L A+ V+ A L ++D Sbjct: 168 AILSGVSWGASAIVAKRLYARHPR--VDLLSLTSWQMLYAALVMSVVA-LLVPQREIDWQ 224 Query: 182 AQVIGLQLYSATFGIAIAYWAINKVNHSLPAMTTSLGLLGVPVFGIVCSSLALGETLEFS 241 V YSA A+A+ V +LPA SL L VPV G++ S LGE Sbjct: 225 PTVFWALAYSAILATALAWSLWLFVLKNLPASIASLSTLAVPVCGVLFSWWLLGENPGAV 284 Query: 242 LVASMALIIMGIAIGALPEKRAV 264 + + LI++ +A+ + +K AV Sbjct: 285 EGSGIVLIVLALALVSRKKKEAV 307 >ECs4872 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ecs Escherichia coli O157:H7 Length = 312 Score = 85.1 bits (209), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 81/263 (30%), Positives = 118/263 (44%), Gaps = 13/263 (4%) Query: 7 TAIRSCIGTVVLLILCLARGRLVLPQRGDLPVVFSVGLLHMTAYSILGNVGMQHVAAGRS 66 TA+R G +VL I+ L RGR + P ++ LL L + AG+ Sbjct: 53 TALRCIFGALVLFIVLLLRGRGMRPT--PFKYTLAIALLQTCGMVGLAQWALVSGGAGKV 110 Query: 67 VVLAYTTPMWVAPCARLFLGEAFTLRRAIGTVFGLFGLVLIFNPLAFDWSNHDSVLGNGL 126 +L+YT P WV A +FLGE + + FGL L+ P D+S+ S + L Sbjct: 111 AILSYTMPFWVVIFAAVFLGERLRRGQYFAILIAAFGLFLVLQPWQLDFSSMKSAM---L 167 Query: 127 ILLGAMFWAASI-----LYVRGHRWIGEPFDLLVWQALTASCVLVPCAWLFEGPPQLDLS 181 +L + W AS LY R R + L WQ L A+ V+ A L ++D Sbjct: 168 AILSGVSWGASAIVAKRLYARHPR--VDLLSLTSWQMLYAALVMSVVA-LLVPQREIDWQ 224 Query: 182 AQVIGLQLYSATFGIAIAYWAINKVNHSLPAMTTSLGLLGVPVFGIVCSSLALGETLEFS 241 V YSA A+A+ V +LPA SL L VPV G++ S LGE Sbjct: 225 PTVFWALAYSAILATALAWSLWLFVLKNLPASIASLSTLAVPVCGVLFSWWLLGENPGAV 284 Query: 242 LVASMALIIMGIAIGALPEKRAV 264 + + LI++ +A+ + +K AV Sbjct: 285 EGSGIVLIVLALALVSRKKKEAV 307 >BS_yoaV [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bsu Bacillus subtilis Length = 292 Score = 81.3 bits (199), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 66/265 (24%), Positives = 123/265 (46%), Gaps = 11/265 (4%) Query: 3 PIWSTAIRSCIGTV-VLLILCLARGRLVLPQRGDLPVVFSVGLLHMTAYSILGNVGMQHV 61 P+ + +R IG V + LIL + R +L + Q+ L + LL Y + GMQ V Sbjct: 31 PLLFSGLRLFIGAVPLFLILFIQRKKLSI-QKEHLKSYIIMSLLMGLGYMGILTYGMQFV 89 Query: 62 AAGRSVVLAYTTPMWVAPCARLFLGEAFTLRRAIGTVFGLFGLVLIFNPLAFDWSNHDSV 121 +G++ VL YT P++V + L E + + +G V GLFGL+ IF + + ++ Sbjct: 90 DSGKTSVLVYTMPIFVTVISHFSLNEKMNVYKTMGLVCGLFGLLFIFGKEMLN-IDQSAL 148 Query: 122 LGNGLILLGAMFWAASILYVRGHRWIGEPFDLLVWQALTASCVLVPCAWLFEGPPQLDLS 181 G +L+ A+ W + ++ + + + W + + +L+ +++FE P + + Sbjct: 149 FGELCVLVAALSWGIANVFSKLQFKHIDIIHMNAWHLMMGAVMLLVFSFIFEAVPSAEWT 208 Query: 182 AQVIGLQLY----SATFGIAIAYWAINKVNHSLPAMTTSLGLLGVPVFGIVCSSLALGET 237 Q + L+ S F + +W +N++ S S+ L+ VPV + L L E Sbjct: 209 YQAVWSLLFNGLLSTGFTFVVWFWVLNQIQAS----KASMALMFVPVLALFFGWLQLHEQ 264 Query: 238 LEFSLVASMALIIMGIAIGALPEKR 262 + +++ LI GI + R Sbjct: 265 ITINIILGALLICCGIFMNTFTFSR 289 >BS_ydfC [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bsu Bacillus subtilis Length = 306 Score = 69.7 bits (169), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 65/232 (28%), Positives = 108/232 (46%), Gaps = 15/232 (6%) Query: 10 RSCIGTVVLLILCLARGRLVLPQRGDLPVVFSVGLLHMTAYSILGNVGMQHVAAGRSVVL 69 R IG++ LL+ + ++ LP D+P +F +G L Y IL N+G + V+AG + +L Sbjct: 42 RLLIGSMALLLFAVLT-QMRLPDLKDIPAIFLLGFLGFAFYHILLNIGEKTVSAGVASLL 100 Query: 70 AYTTPMWVAPCARLFLGEAFTLRRAIGTVFGLFGLVLIFNPLAFDWSNHDSVLGNGLILL 129 T P++ A +RLF E F + +G++ L G++LI AF + + L++L Sbjct: 101 VTTAPIFSAMLSRLFYKEHFGFTKWLGSMISLLGVLLI----AFGAGDFTYSMSGILVIL 156 Query: 130 GAMFWAASILYVRGHRWIGE----PF-DLLVWQALTASCVLVPCAWLFEGPPQLDLSAQV 184 A F + SI +V R+I + PF +W V +P G ++ S Sbjct: 157 LAAF-SESIYFVFQARYIKKYGFIPFVTFTIWGGTIPMLVFLPGL----GEEMMNASISA 211 Query: 185 IGLQLYSATFGIAIAYWAINKVNHSLPAMTTSLGLLGVPVFGIVCSSLALGE 236 +Y I Y+A+ V + A +L L P ++ S L +GE Sbjct: 212 TLSIVYLGLLPTVIPYFALAYVTSFVGASEATLSLYVTPALALIISWLWIGE 263