BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0006.p (521 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1292 [GEPR] COG0477 Permeases of the major facilitator superf... 664 0.0 YPO3268 [GEPR] COG0477 Permeases of the major facilitator superf... 518 e-146 STM2815 [GEPR] COG0477 Permeases of the major facilitator superf... 517 e-146 emrB [GEPR] COG0477 Permeases of the major facilitator superfami... 509 e-144 ECs3548 [GEPR] COG0477 Permeases of the major facilitator superf... 509 e-144 >RSc1292 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 518 Score = 664 bits (1713), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/512 (64%), Positives = 405/512 (79%), Gaps = 1/512 (0%) Query: 10 PPPPLTGGKLVLGTLCVSLAVFMNVLDSSIANVAIPTISGNLGVSIDEGTWVITSFAAAN 69 P PLTG KL +GT+ +SLA FMNVLDSSIANV+IP ISG+LGV+ ++GTWVITSFA AN Sbjct: 8 PLQPLTGAKLAIGTVALSLATFMNVLDSSIANVSIPAISGDLGVAPNQGTWVITSFAVAN 67 Query: 70 AISIPLTGWLTQRIGAVRLFVSSVLLFVLASWLCGLAPTLPILLGARVLQGLVAGPMVPL 129 AIS+PLTGWLTQR G VRLFV+S+LLFVL+SW CGLAP + L+ AR+LQG VAGPM+PL Sbjct: 68 AISVPLTGWLTQRFGQVRLFVTSILLFVLSSWACGLAPNMGTLIAARILQGAVAGPMIPL 127 Query: 130 SQSLLLGAYPKSKASFALALWGMTAVVAPVAGPALGGWITDAYTWPWIFYINIPVGLLAA 189 SQSLLL YP +K+S ALALWGMT +VAP+ GP GGWI+D TWPWIFYINIPVG+LAA Sbjct: 128 SQSLLLSTYPPAKSSMALALWGMTTLVAPIMGPIFGGWISDNMTWPWIFYINIPVGILAA 187 Query: 190 GMTMAIYKDRESPTHKLPIDTIGLLLLITWVAAFQIMLDKGKDLDWFASPTIVTLGIIAA 249 T IYKDRESPT LPID IGL LL+ WV + Q+MLD+GK+LDWF S IVTL ++A Sbjct: 188 YATWVIYKDRESPTRALPIDRIGLALLVIWVGSLQLMLDRGKELDWFNSAEIVTLTVVAV 247 Query: 250 VAFAYFVIWELNNDHPVVDLRLFGRRNFFGGTVAISIGYGVFFGNLVLLPQWLQQYLGYR 309 V FA+F++WEL DHPVVDL LF RNF G VAIS+ YG+FFGNLV+LP WLQ +GY Sbjct: 248 VGFAFFLVWELTEDHPVVDLTLFKGRNFSAGVVAISVAYGLFFGNLVILPLWLQTIVGYT 307 Query: 310 SIDSGLSTAPIGIFAVILMPLIGKFLPRMDARKVATASFVGFACVFFMRSRYNLEVDQWT 369 + D+GL AP+GIFA++L P+IGK LP+MDAR VAT +F+ FA VF+MRSR+ ++VD WT Sbjct: 308 ATDAGLVMAPVGIFAILLSPVIGKNLPKMDARWVATTAFITFALVFWMRSRFTIQVDTWT 367 Query: 370 VILPTLLQGIPTAMFFVPLTVLLLSGLPPERIPAAAGLSSFVRVFCGAIGTSVATTAWNN 429 +++PTL+QG AMFF+PLT ++LSGL PERIPAA+GLS+FVR+ G IG S++TT W+N Sbjct: 368 LMVPTLIQGAAMAMFFIPLTSIILSGLRPERIPAASGLSNFVRIMFGGIGASISTTVWDN 427 Query: 430 RTIVHHAQLTEHATPYSTALQQMFSNLTGNFGMSTEQATGLIERNLNAQAAMIGINDIFW 489 R+ +HHAQL E A PY+ A + T GM + QA G IER ++ QAAM+G NDIFW Sbjct: 428 RSALHHAQLVERANPYNPAYASSLGDYT-QMGMPSLQANGAIERIISQQAAMMGANDIFW 486 Query: 490 LSGVIFLVIIPVIWIIKPAKGNAGAEAAAAAH 521 +S V+F+V+I +IW+ +PAK GAEAAA AH Sbjct: 487 ISAVLFIVLIALIWLTRPAKSAGGAEAAAGAH 518 >YPO3268 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 511 Score = 518 bits (1333), Expect = e-146, Method: Compositional matrix adjust. Identities = 261/497 (52%), Positives = 347/497 (69%), Gaps = 4/497 (0%) Query: 13 PLTGGKLVLGTLCVSLAVFMNVLDSSIANVAIPTISGNLGVSIDEGTWVITSFAAANAIS 72 PL G L T+ +SLA FM VLDS+IANVAIPTI+G+LG S +GTWVITSF ANAIS Sbjct: 5 PLEGAPLAWMTVALSLATFMQVLDSTIANVAIPTIAGDLGSSNSQGTWVITSFGVANAIS 64 Query: 73 IPLTGWLTQRIGAVRLFVSSVLLFVLASWLCGLAPTLPILLGARVLQGLVAGPMVPLSQS 132 IP+TGWL +R+G VRLF+ S LFVLASWLCG++ +L +L+ RV+QGLVAGP++PLSQS Sbjct: 65 IPVTGWLAKRVGEVRLFLWSTGLFVLASWLCGMSNSLGMLIFFRVIQGLVAGPLIPLSQS 124 Query: 133 LLLGAYPKSKASFALALWGMTAVVAPVAGPALGGWITDAYTWPWIFYINIPVGLLAAGMT 192 LLL YP +K S ALALW MT VVAP+ GP LGG+I+D Y W WIF+INIP+GL+ + Sbjct: 125 LLLNNYPPAKRSMALALWSMTIVVAPIFGPILGGYISDNYHWGWIFFINIPIGLVVVLLA 184 Query: 193 MAIYKDRESPTHKLPIDTIGLLLLITWVAAFQIMLDKGKDLDWFASPTIVTLGIIAAVAF 252 + K RE+ T PIDTIGL+LL+ + A QIMLD+GK+LDWF S I+ L ++A VA Sbjct: 185 GSTLKGRETKTEIRPIDTIGLVLLVVGIGALQIMLDQGKELDWFNSTEIIVLTVVAVVAI 244 Query: 253 AYFVIWELNNDHPVVDLRLFGRRNFFGGTVAISIGYGVFFGNLVLLPQWLQQYLGYRSID 312 + ++WEL +DHPV+DL LF RNF G + +S+ Y ++FG +VLLPQ LQ+ GY + Sbjct: 245 TFLIVWELTDDHPVIDLSLFKSRNFTIGCLCLSLAYMLYFGAIVLLPQLLQEVYGYTATW 304 Query: 313 SGLSTAPIGIFAVILMPLIGKFLPRMDARKVATASFVGFACVFFMRSRYNLE--VDQWTV 370 +GL++AP+GI V+L PLIG+F R+D R++ T SF+ +A F+ R+ Y E +D Sbjct: 305 AGLASAPVGILPVLLSPLIGRFAHRIDMRQLVTFSFIMYAVCFYWRA-YTFEPGMDFGAS 363 Query: 371 ILPTLLQGIPTAMFFVPLTVLLLSGLPPERIPAAAGLSSFVRVFCGAIGTSVATTAWNNR 430 P QG A FF+PLT + LSGLPPER+ AA+ LS+F+R G+IGTS+ TT W R Sbjct: 364 AWPQFFQGFAIACFFMPLTTITLSGLPPERMAAASSLSNFMRTLAGSIGTSITTTLWTQR 423 Query: 431 TIVHHAQLTEHATPYSTALQQMFSNLTGNFGMSTEQATGLIERNLNAQAAMIGINDIFWL 490 +HHAQLTE PY+ Q + L GMS +QA+ + R + Q +I N+IFWL Sbjct: 424 ESLHHAQLTEFVNPYNPNATQAYQELE-KLGMSQQQASAYLAREITNQGLIISANEIFWL 482 Query: 491 SGVIFLVIIPVIWIIKP 507 S +FL+++ +IW +P Sbjct: 483 SAGVFLMLLALIWFARP 499 >STM2815 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 512 Score = 517 bits (1331), Expect = e-146, Method: Compositional matrix adjust. Identities = 252/496 (50%), Positives = 350/496 (70%), Gaps = 2/496 (0%) Query: 13 PLTGGKLVLGTLCVSLAVFMNVLDSSIANVAIPTISGNLGVSIDEGTWVITSFAAANAIS 72 PL G +LV+ T+ +SLA FM VLDS+IANVAIPTI+GNLG S+ +GTWVITSF ANAIS Sbjct: 6 PLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAIS 65 Query: 73 IPLTGWLTQRIGAVRLFVSSVLLFVLASWLCGLAPTLPILLGARVLQGLVAGPMVPLSQS 132 IPLTGWL +R G V+LF+ S + F ASW CG++ +L +L+ RV+QG+VAGP++PLSQS Sbjct: 66 IPLTGWLAKRFGEVKLFMWSTVAFAAASWACGVSSSLNMLIFFRVVQGVVAGPLIPLSQS 125 Query: 133 LLLGAYPKSKASFALALWGMTAVVAPVAGPALGGWITDAYTWPWIFYINIPVGLLAAGMT 192 LLL YP +K S ALALW MT +VAP+ GP LGG+I+D Y W WIF+IN+P+G+ MT Sbjct: 126 LLLNNYPPAKRSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGIAVVLMT 185 Query: 193 MAIYKDRESPTHKLPIDTIGLLLLITWVAAFQIMLDKGKDLDWFASPTIVTLGIIAAVAF 252 + + RE+ T + ID +GL LL+ + + QIMLD+GK+LDWF+S I+ L ++A +A Sbjct: 186 LHTLRGRETHTERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVIAI 245 Query: 253 AYFVIWELNNDHPVVDLRLFGRRNFFGGTVAISIGYGVFFGNLVLLPQWLQQYLGYRSID 312 ++ ++WEL +DHP+VDL LF RNF G + IS+ Y ++FG +VLLPQ LQ+ GY + Sbjct: 246 SFLIVWELTDDHPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTATW 305 Query: 313 SGLSTAPIGIFAVILMPLIGKFLPRMDARKVATASFVGFACVFFMRS-RYNLEVDQWTVI 371 +GL++AP+GI VIL P+IG+F ++D R++ T SF+ +A F+ R+ + +D Sbjct: 306 AGLASAPVGIIPVILSPIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAWTFEPGMDFGASA 365 Query: 372 LPTLLQGIPTAMFFVPLTVLLLSGLPPERIPAAAGLSSFVRVFCGAIGTSVATTAWNNRT 431 P +QG A FF+PLT + LSGLPPER+ AA+ LS+F R G+IGTS+ TT W +R Sbjct: 366 WPQFIQGFAVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSITTTMWTDRE 425 Query: 432 IVHHAQLTEHATPYSTALQQMFSNLTGNFGMSTEQATGLIERNLNAQAAMIGINDIFWLS 491 +HHAQLTE T Y+ Q M+ L G GM+ +QA+G I + + Q +I N+IFW+S Sbjct: 426 SLHHAQLTESVTAYNPNAQTMYDKLEG-LGMTHQQASGWIAQQITNQGLIISANEIFWMS 484 Query: 492 GVIFLVIIPVIWIIKP 507 IFLV++ ++W KP Sbjct: 485 AGIFLVLLGLVWFAKP 500 >emrB [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 512 Score = 509 bits (1310), Expect = e-144, Method: Compositional matrix adjust. Identities = 255/497 (51%), Positives = 353/497 (71%), Gaps = 4/497 (0%) Query: 13 PLTGGKLVLGTLCVSLAVFMNVLDSSIANVAIPTISGNLGVSIDEGTWVITSFAAANAIS 72 PL G +LV+ T+ +SLA FM VLDS+IANVAIPTI+GNLG S+ +GTWVITSF ANAIS Sbjct: 6 PLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAIS 65 Query: 73 IPLTGWLTQRIGAVRLFVSSVLLFVLASWLCGLAPTLPILLGARVLQGLVAGPMVPLSQS 132 IPLTGWL +R+G V+LF+ S + F +ASW CG++ +L +L+ RV+QG+VAGP++PLSQS Sbjct: 66 IPLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSLNMLIFFRVIQGIVAGPLIPLSQS 125 Query: 133 LLLGAYPKSKASFALALWGMTAVVAPVAGPALGGWITDAYTWPWIFYINIPVGLLAAGMT 192 LLL YP +K S ALALW MT +VAP+ GP LGG+I+D Y W WIF+IN+P+G+ MT Sbjct: 126 LLLNNYPPAKRSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVLMT 185 Query: 193 MAIYKDRESPTHKLPIDTIGLLLLITWVAAFQIMLDKGKDLDWFASPTIVTLGIIAAVAF 252 + + RE+ T + ID +GL LL+ + + QIMLD+GK+LDWF+S I+ L ++A VA Sbjct: 186 LQTLRGRETRTERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVVAI 245 Query: 253 AYFVIWELNNDHPVVDLRLFGRRNFFGGTVAISIGYGVFFGNLVLLPQWLQQYLGYRSID 312 + ++WEL +D+P+VDL LF RNF G + IS+ Y ++FG +VLLPQ LQ+ GY + Sbjct: 246 CFLIVWELTDDNPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTATW 305 Query: 313 SGLSTAPIGIFAVILMPLIGKFLPRMDARKVATASFVGFACVFFMRSRYNLE--VDQWTV 370 +GL++AP+GI VIL P+IG+F ++D R++ T SF+ +A F+ R+ Y E +D Sbjct: 306 AGLASAPVGIIPVILSPIIGRFAHKLDMRRLVTFSFIMYAVCFYWRA-YTFEPGMDFGAS 364 Query: 371 ILPTLLQGIPTAMFFVPLTVLLLSGLPPERIPAAAGLSSFVRVFCGAIGTSVATTAWNNR 430 P +QG A FF+PLT + LSGLPPER+ AA+ LS+F R G+IGTS+ TT W NR Sbjct: 365 AWPQFIQGFAVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSITTTMWTNR 424 Query: 431 TIVHHAQLTEHATPYSTALQQMFSNLTGNFGMSTEQATGLIERNLNAQAAMIGINDIFWL 490 +HHAQLTE P++ Q M+S L G GM+ +QA+G I + + Q +I N+IFW+ Sbjct: 425 ESMHHAQLTESVNPFNPNAQAMYSQLEG-LGMTQQQASGWIAQQITNQGLIISANEIFWM 483 Query: 491 SGVIFLVIIPVIWIIKP 507 S IFLV++ ++W KP Sbjct: 484 SAGIFLVLLGLVWFAKP 500 >ECs3548 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 512 Score = 509 bits (1310), Expect = e-144, Method: Compositional matrix adjust. Identities = 255/497 (51%), Positives = 353/497 (71%), Gaps = 4/497 (0%) Query: 13 PLTGGKLVLGTLCVSLAVFMNVLDSSIANVAIPTISGNLGVSIDEGTWVITSFAAANAIS 72 PL G +LV+ T+ +SLA FM VLDS+IANVAIPTI+GNLG S+ +GTWVITSF ANAIS Sbjct: 6 PLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAIS 65 Query: 73 IPLTGWLTQRIGAVRLFVSSVLLFVLASWLCGLAPTLPILLGARVLQGLVAGPMVPLSQS 132 IPLTGWL +R+G V+LF+ S + F +ASW CG++ +L +L+ RV+QG+VAGP++PLSQS Sbjct: 66 IPLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSLNMLIFFRVIQGIVAGPLIPLSQS 125 Query: 133 LLLGAYPKSKASFALALWGMTAVVAPVAGPALGGWITDAYTWPWIFYINIPVGLLAAGMT 192 LLL YP +K S ALALW MT +VAP+ GP LGG+I+D Y W WIF+IN+P+G+ MT Sbjct: 126 LLLNNYPPAKRSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVLMT 185 Query: 193 MAIYKDRESPTHKLPIDTIGLLLLITWVAAFQIMLDKGKDLDWFASPTIVTLGIIAAVAF 252 + + RE+ T + ID +GL LL+ + + QIMLD+GK+LDWF+S I+ L ++A VA Sbjct: 186 LQTLRGRETRTERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVVAI 245 Query: 253 AYFVIWELNNDHPVVDLRLFGRRNFFGGTVAISIGYGVFFGNLVLLPQWLQQYLGYRSID 312 + ++WEL +D+P+VDL LF RNF G + IS+ Y ++FG +VLLPQ LQ+ GY + Sbjct: 246 CFLIVWELTDDNPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTATW 305 Query: 313 SGLSTAPIGIFAVILMPLIGKFLPRMDARKVATASFVGFACVFFMRSRYNLE--VDQWTV 370 +GL++AP+GI VIL P+IG+F ++D R++ T SF+ +A F+ R+ Y E +D Sbjct: 306 AGLASAPVGIIPVILSPIIGRFAHKLDMRRLVTFSFIMYAVCFYWRA-YTFEPGMDFGAS 364 Query: 371 ILPTLLQGIPTAMFFVPLTVLLLSGLPPERIPAAAGLSSFVRVFCGAIGTSVATTAWNNR 430 P +QG A FF+PLT + LSGLPPER+ AA+ LS+F R G+IGTS+ TT W NR Sbjct: 365 AWPQFIQGFAVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSITTTMWTNR 424 Query: 431 TIVHHAQLTEHATPYSTALQQMFSNLTGNFGMSTEQATGLIERNLNAQAAMIGINDIFWL 490 +HHAQLTE P++ Q M+S L G GM+ +QA+G I + + Q +I N+IFW+ Sbjct: 425 ESMHHAQLTESVNPFNPNAQAMYSQLEG-LGMTQQQASGWIAQQITNQGLIISANEIFWM 483 Query: 491 SGVIFLVIIPVIWIIKP 507 S IFLV++ ++W KP Sbjct: 484 SAGIFLVLLGLVWFAKP 500