BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0006.0046.p (349 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value alr2428_7 [T] COG0642 Signal transduction histidine kinase Nos N... 107 4e-23 all3985_2 [T] COG0642 Signal transduction histidine kinase Nos N... 107 4e-23 TM1654_2 [T] COG0642 Signal transduction histidine kinase Tma Th... 102 1e-21 VCA0709_1 [T] COG0642 Signal transduction histidine kinase Vch V... 102 1e-21 alr1171 [T] COG0642 Signal transduction histidine kinase Nos Nos... 101 2e-21 >alr2428_7 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 256 Score = 107 bits (267), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 71/230 (30%), Positives = 129/230 (56%), Gaps = 11/230 (4%) Query: 122 REEYLSFIAHDLRTPLNAVALASKVLESTLGAQNADPRAARMIKVLQRNVQSMSGLVAKV 181 ++E++S ++H+LRTPL ++ + +L S L + +++ + R++++ + + + L+ + Sbjct: 2 KDEFVSVVSHELRTPLTSIHGSLGMLASGLLSADSE-QGKRLLEIATDSTERLVRLINDI 60 Query: 182 IEENDNMKTESG-VKLERRNIDLWPLVESMVYDLNPVAGTGSTRLLNDVPEDLVIYADAN 240 + D + ESG VK+ER + DL L+ES V + P+A +L P + ++ D + Sbjct: 61 L---DIERIESGRVKMERESCDLSDLIESAVSIMQPLANKAGVKLSVSSPS-IQLWVDPD 116 Query: 241 LLRRMMQNLIANAITHTPQGEVVIGAAPTLDGAGIECWVSDNGMGISKDRLALIFEKFE- 299 + + + NL++NAI + + V A G + V DNG GI D+L IFE+F+ Sbjct: 117 RIVQTLTNLLSNAIKFSTAEKTVWLVAQHY-GDELLLTVKDNGRGIPADKLDSIFERFQQ 175 Query: 300 ---TETKDHGGLGLGLAIFKTFVEAHEGSFDVVSEPGKGSRFSFILPNRP 346 +++++H G GLGLAI ++ ++ H G S G+GS F F LP P Sbjct: 176 VDSSDSRNHDGTGLGLAICQSIIQQHGGRIWAESVLGEGSNFYFTLPILP 225 >all3985_2 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 252 Score = 107 bits (267), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 66/231 (28%), Positives = 134/231 (58%), Gaps = 18/231 (7%) Query: 122 REEYLSFIAHDLRTPLNAVALASKVLESTLGAQNADPRAARMIKVLQRNVQSMSGLVAKV 181 ++E+L+ ++H+LR+PLN + S++L + + + + + ++ ++RN Q+ + L+ + Sbjct: 2 KDEFLAIVSHELRSPLNGILGWSRLLRT---RKLSPEKIEQALESIERNAQAQTQLIEDL 58 Query: 182 IEENDNMKTESGVKLERRNIDLWPLVESMVYDLNPVAGTGSTRLLNDVPEDL-VIYADAN 240 ++ + ++ ++L R L P++++ + + P+A T S ++++ + D+ ++ AD Sbjct: 59 LDISRIIR--GNIRLLVRPTKLIPVIQAALDTVRPIANTKSIQIISRLNFDIGLVSADPE 116 Query: 241 LLRRMMQNLIANAITHTPQG---EVVIGAAPTLDGAGIECWVSDNGMGISKDRLALIFEK 297 L++++ NL++NA+ TP+G E+ + T ++ V D G GIS + L +F++ Sbjct: 117 RLQQVIWNLLSNAVKFTPEGGRVEICLEQVET----NVQIQVIDTGTGISPEFLPYVFDR 172 Query: 298 FE----TETKDHGGLGLGLAIFKTFVEAHEGSFDVVSE-PGKGSRFSFILP 343 F T T++ GGLGLGLAI + VE H G V S G+G+ F+ LP Sbjct: 173 FRQADATTTRNQGGLGLGLAIVRNLVELHNGKVSVASPGEGQGATFTVQLP 223 >TM1654_2 [T] COG0642 Signal transduction histidine kinase Tma Thermotoga maritima Length = 272 Score = 102 bits (255), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 80/271 (29%), Positives = 139/271 (51%), Gaps = 21/271 (7%) Query: 88 QGKPFHV--INLVFDSAIGLAVQTF-SVNRALEVQRRREEYLSFIAHDLRTPLNAV-ALA 143 + K FHV I + S + V F V + ++ R E+++ ++H+LRTPL ++ A Sbjct: 9 EKKYFHVKVIPVELKSGDKIFVILFHDVTKERKLDEMRREFIATVSHELRTPLTSIHGYA 68 Query: 144 SKVLESTLGAQNADPRAARMIKVLQRNVQSMSGLVAKVIEENDNMKTESGVKLERRNIDL 203 +LE L + R +K+++ M+ L+ +++ ++E+ E +++DL Sbjct: 69 ETLLEDDLENKEL---VKRFLKIIEEESARMTRLINDLLDLEKIEESEAN--FEMKDVDL 123 Query: 204 WPLVESMVYDLNPVAGTGSTRLLNDVPEDLVIYADANLLRRMMQNLIANAITHTP---QG 260 ++E + + P+A L+ + ED+V+ + L +M+ NL+ NA+ +T +G Sbjct: 124 CEVIEYVYRIIQPIAEENEVDLIVEC-EDVVVRGNKERLIQMLLNLVDNAVKYTSLKEKG 182 Query: 261 E--VVIGAAPTLDGAGIECWVSDNGMGISKDRLALIFEKF----ETETKDHGGLGLGLAI 314 E V + A T D +E V D G GI K+ + IFEKF + ++ GG GLGL I Sbjct: 183 EKKVWVRAYDTPDWVVVE--VEDTGPGIPKEAQSRIFEKFYRVDKARSRKMGGTGLGLTI 240 Query: 315 FKTFVEAHEGSFDVVSEPGKGSRFSFILPNR 345 KT V+ H G +V SE +G+ +LP R Sbjct: 241 VKTIVDKHGGKIEVESEINQGTLMRVLLPKR 271 >VCA0709_1 [T] COG0642 Signal transduction histidine kinase Vch Vibrio cholerae Length = 738 Score = 102 bits (254), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 70/237 (29%), Positives = 122/237 (51%), Gaps = 13/237 (5%) Query: 113 NRALEVQRRREEYLSFIAHDLRTPLNAVALASKVLESTLGAQNADPRAARMIKVLQRNVQ 172 +A + R + +L+ ++H++RTP+N V +++L+ T ++V+ R+ + Sbjct: 497 QQAEQASRAKSAFLATMSHEIRTPMNGVLGTARLLQDT----TLTSTQQHYVQVINRSGR 552 Query: 173 SMSGLVAKVIEENDNMKTESG-VKLERRNIDLWPLVESMVYDLNPVAGTGSTRLLNDVPE 231 S+ ++ V+ D K E+G +++ + DL+ LV + A L + E Sbjct: 553 SLLAILNDVL---DYSKIEAGHLEIHHTHFDLYRLVSETHELMQSRAREKGITLTYHIDE 609 Query: 232 DLVIYADANLLR--RMMQNLIANAITHTPQGEVVIGAAPTLDGAGIECWVSDNGMGISKD 289 D+ Y + +R +++ NL+ N I T QGEV I DG GI V D+G+GI+++ Sbjct: 610 DVTQYWQGDEIRIGQVLNNLVGNGIKFTDQGEVRIRIRLAPDGQGIRFAVEDSGIGIAEE 669 Query: 290 RLALIFEKF---ETETKDHGGLGLGLAIFKTFVEAHEGSFDVVSEPGKGSRFSFILP 343 A +F+ F + + GG GLGLAI + V+A G + S+ G+GS F F LP Sbjct: 670 EQATLFDAFTQADAGRRKLGGTGLGLAISRKLVQAMGGELQLASQLGQGSCFWFTLP 726 >alr1171 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 448 Score = 101 bits (252), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 80/244 (32%), Positives = 125/244 (51%), Gaps = 20/244 (8%) Query: 104 GLAVQTFSVNRALEVQRRREEYLSFIAHDLRTPLNAVALASKVLESTLGAQNAD-PRAAR 162 GLA+Q + R+ +++ + AH+LRTPL A +ES L D P Sbjct: 211 GLAMQPI-----YQSYRQIQQFTADAAHELRTPLAATG---ATVESALLMPKIDEPETRD 262 Query: 163 MIKVLQRNVQSMSGLVAKVIEENDNMKTESGVKLERRNIDLWPLVESMVYDLNPVAGTGS 222 +++ +QR Q ++ LV ++ KL+R L +V ++ + +A Sbjct: 263 ILQTIQRQNQRLTTLVVDLLMLAR--LDRQAQKLQREVCCLNDIVSDLIEEFAAMANAAG 320 Query: 223 TRLLND--VPEDLVIYADANLLRRMMQNLIANAITHTPQG-EVVIGAAPTLDGAGIECWV 279 +L+ V ++L I +++ L R++ NLI NAI +TP+G EV + + A I+ V Sbjct: 321 VKLIYSIRVKQNLNIMGNSDQLYRLLSNLIVNAIQYTPKGGEVTVILERNDNYAVIK--V 378 Query: 280 SDNGMGISKDRLALIFEKFETETKDH----GGLGLGLAIFKTFVEAHEGSFDVVSEPGKG 335 D G+GI + L IF++F + D GG GLGLAI + EAH+GS DV SE GKG Sbjct: 379 QDTGIGIPQHELTRIFDRFYRVSSDRSRNTGGSGLGLAIVQAITEAHQGSIDVQSELGKG 438 Query: 336 SRFS 339 S F+ Sbjct: 439 STFT 442