BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0299.p (377 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value all1716_5 [T] COG0642 Signal transduction histidine kinase Nos N... 108 1e-23 MA1149_2 [T] COG0642 Signal transduction histidine kinase Mac Me... 105 1e-22 BS_resE_4 [T] COG0642 Signal transduction histidine kinase Bsu B... 105 2e-22 ECs3107_1 [T] COG0642 Signal transduction histidine kinase Ecs E... 103 6e-22 ZrcsC_1 [T] COG0642 Signal transduction histidine kinase EcZ Esc... 103 6e-22 >all1716_5 [T] COG0642 Signal transduction histidine kinase Nos Nostoc sp. PCC 7120 Length = 332 Score = 108 bits (271), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 78/244 (31%), Positives = 128/244 (52%), Gaps = 12/244 (4%) Query: 134 ALAESVGTYAAQASRAKDTFLAILGHDLRNPLATIALSSSLLGQPGMTKEGIALLAPRIK 193 A +S A A+ AKD FL+IL H+LRNPL ++ ++LL + + + I+ Sbjct: 60 AQEQSARNAAEAANHAKDEFLSILSHELRNPLNSMLGWANLLRTHQLEEVTVNQGLEAIE 119 Query: 194 RSASMMNSMINDLLEYARAELGGEMPMSFADVDMLDICHAAVVDASAVHAHCSFVVNAK- 252 RSA N +I+DLL+ +R G + M +V+++ + AA+ + + K Sbjct: 120 RSAQAQNHLISDLLDVSRIS-SGRLRMDAQEVELIPVIEAAIAVVRLAAEAKNIQIETKL 178 Query: 253 ----EPVLGCFDQIRLQQVFTNLLNNAAQYRGDEMPVTMTLSSDADSATISIQNSGALIP 308 P+LG D IRLQQV NLL+NA ++ + + +TL A I ++++GA I Sbjct: 179 DPTHTPMLG--DPIRLQQVIWNLLSNAIKFTPTKGRIDVTLEYTYFQAQIQVKDTGAGIK 236 Query: 309 KEAIDAIFDPMVQLAIVPEQRERATTSLGLGLYIAKKIAEAHDGSIGVESR-DSTGTTFT 367 + + +F+ Q R R+ LGLGL I + + E H G++ VES+ + G+TFT Sbjct: 237 ADFLPYVFERFRQ---ADGTRTRSNQGLGLGLSIVRHLVELHGGTVEVESQGEGQGSTFT 293 Query: 368 VVIP 371 + +P Sbjct: 294 IKLP 297 >MA1149_2 [T] COG0642 Signal transduction histidine kinase Mac Methanosarcina acetivorans str.C2A Length = 279 Score = 105 bits (263), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 76/238 (31%), Positives = 119/238 (50%), Gaps = 10/238 (4%) Query: 143 AAQASRAKDTFLAILGHDLRNPL-ATIALSSSLLGQP-GMTKEGIALLAPRIKRSASMMN 200 A A+RAK F+ + H+LR PL A I S LL + G E I +S S + Sbjct: 14 AEAANRAKINFIVNMSHELRTPLNAVIGFSDLLLSETAGPLNEKQKRYTENISKSGSHLL 73 Query: 201 SMINDLLEYARAELGGEMPMSFADVDMLDICHAAVVDASAVHAHCSFVVNAK-EPVLGCF 259 +IND+L+ +R ELG + + + VD+ + S++ A + + K E L Sbjct: 74 DVINDVLDISRLELGN-IELYYETVDIPGVIEEVRRVLSSLSAEKNIRIEYKVEQGLKTI 132 Query: 260 D--QIRLQQVFTNLLNNAAQYRGDEMPVTMTLSSDADSATISIQNSGALIPKEAIDAIFD 317 D +++ +Q+ NLLNNA ++ ++ V + S+ D IS+++ G I + +F Sbjct: 133 DVDRVKFKQILYNLLNNAIKFSSEDGKVNIKARSEGDMVEISVKDEGIGINEADYARVFL 192 Query: 318 PMVQLAIVPEQRERATTSLGLGLYIAKKIAEAHDGSIGVESRDSTGTTFTVVIPKLRP 375 P VQ + E R +GLGL + K+ E H G + VE+ G+TFT IPK RP Sbjct: 193 PFVQ---IDESISRKHGGVGLGLALVKRFVELHGGQVWVEASPGKGSTFTFRIPK-RP 246 >BS_resE_4 [T] COG0642 Signal transduction histidine kinase Bsu Bacillus subtilis Length = 269 Score = 105 bits (261), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 76/274 (27%), Positives = 138/274 (50%), Gaps = 20/274 (7%) Query: 107 RLWFSLGNALTPAHSADLIRFNEAIDQALAESVGTYAAQASRAKDTFLAILGHDLRNPLA 166 R W L ++P ++ +R A+ + + E + + ++ F+A + H+LR P++ Sbjct: 10 RSWVLL---MSPLYAESHVRGAVAVLRDMTEE-----RRLDKLREDFIANVSHELRTPIS 61 Query: 167 TI-ALSSSLLGQPGMTKEGIALLAPRIKRSASMMNSMINDLLEYARAELGGEMPMSFADV 225 + S +++ ++E +A I + M ++NDLL+ AR E G + + + Sbjct: 62 MLQGYSEAIVDDIASSEEDRKEIAQIIYDESLRMGRLVNDLLDLARME-SGHTGLHYEKI 120 Query: 226 DMLDICHAAVVDASAVHAHCSFVVN-----AKEPVLGCFDQIRLQQVFTNLLNNAAQYRG 280 ++ + + S V + ++ +E + FD+ +++QVFTNL++NA ++ Sbjct: 121 NVNEFLEKIIRKFSGVAKEKNIALDHDISLTEEEFM--FDEDKMEQVFTNLIDNALRHTS 178 Query: 281 DEMPVTMTLSSDADSATISIQNSGALIPKEAIDAIFDPMVQLAIVPEQRERATTSLGLGL 340 V++++ S D I I++SG+ IP+E + IF+ + + R R GLGL Sbjct: 179 AGGSVSISVHSVKDGLKIDIKDSGSGIPEEDLPFIFERFYK---ADKARTRGRAGTGLGL 235 Query: 341 YIAKKIAEAHDGSIGVESRDSTGTTFTVVIPKLR 374 I K I EAH+GSI V SR GTTF+ IP R Sbjct: 236 AIVKNIVEAHNGSITVHSRIDKGTTFSFYIPTKR 269 >ECs3107_1 [T] COG0642 Signal transduction histidine kinase Ecs Escherichia coli O157:H7 Length = 700 Score = 103 bits (257), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 73/234 (31%), Positives = 125/234 (53%), Gaps = 12/234 (5%) Query: 143 AAQASRAKDTFLAILGHDLRNPLATIALSSSLLGQPGMTKEGIALLAPRIKRSASMMNSM 202 A QAS++K FLA + H+LR PL I + LL + K G+ L + S+S++ + Sbjct: 447 AEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPK-GVDRLVTAMNNSSSLLLKI 505 Query: 203 INDLLEYARAELGGEM--PMSFADVDMLDICHA---AVVDASAVHAHCSFVVNAKEPVLG 257 I+D+L++++ E M P F+ ++++ A +V + +C + PV Sbjct: 506 ISDILDFSKIESEQLMIEPREFSPREVMNHITANYLPLVVRKQLGLYC--FIEPDVPVAL 563 Query: 258 CFDQIRLQQVFTNLLNNAAQYRGDEMPVTMTLSSDADSATISIQNSGALIPKEAIDAIFD 317 D +RLQQV +NLL+NA ++ D + + + +D D +I ++++G IP + + +FD Sbjct: 564 NGDPMRLQQVISNLLSNAIKF-TDTGCIVLHVRADGDYLSIRVRDTGVGIPAKEVVRLFD 622 Query: 318 PMVQLAIVPEQRERATTSLGLGLYIAKKIAEAHDGSIGVESRDSTGTTFTVVIP 371 P Q+ ++ + T GLGL I +K+ DG I V+S G+ FTV IP Sbjct: 623 PFFQVGTGVQRNFQGT---GLGLAICEKLISMMDGDISVDSEPGMGSQFTVRIP 673 >ZrcsC_1 [T] COG0642 Signal transduction histidine kinase EcZ Escherichia coli O157:H7 EDL933 Length = 700 Score = 103 bits (257), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 73/234 (31%), Positives = 125/234 (53%), Gaps = 12/234 (5%) Query: 143 AAQASRAKDTFLAILGHDLRNPLATIALSSSLLGQPGMTKEGIALLAPRIKRSASMMNSM 202 A QAS++K FLA + H+LR PL I + LL + K G+ L + S+S++ + Sbjct: 447 AEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPK-GVDRLVTAMNNSSSLLLKI 505 Query: 203 INDLLEYARAELGGEM--PMSFADVDMLDICHA---AVVDASAVHAHCSFVVNAKEPVLG 257 I+D+L++++ E M P F+ ++++ A +V + +C + PV Sbjct: 506 ISDILDFSKIESEQLMIEPREFSPREVMNHITANYLPLVVRKQLGLYC--FIEPDVPVAL 563 Query: 258 CFDQIRLQQVFTNLLNNAAQYRGDEMPVTMTLSSDADSATISIQNSGALIPKEAIDAIFD 317 D +RLQQV +NLL+NA ++ D + + + +D D +I ++++G IP + + +FD Sbjct: 564 NGDPMRLQQVISNLLSNAIKF-TDTGCIVLHVRADGDYLSIRVRDTGVGIPAKEVVRLFD 622 Query: 318 PMVQLAIVPEQRERATTSLGLGLYIAKKIAEAHDGSIGVESRDSTGTTFTVVIP 371 P Q+ ++ + T GLGL I +K+ DG I V+S G+ FTV IP Sbjct: 623 PFFQVGTGVQRNFQGT---GLGLAICEKLISMMDGDISVDSEPGMGSQFTVRIP 673