BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0298.p (434 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM0689 [GEPR] COG0477 Permeases of the major facilitator superf... 613 e-175 RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 562 e-160 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 535 e-152 PA5476 [GEPR] COG0477 Permeases of the major facilitator superfa... 491 e-138 RSp0536 [GEPR] COG0477 Permeases of the major facilitator superf... 258 1e-68 >STM0689 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 434 Score = 613 bits (1580), Expect = e-175, Method: Compositional matrix adjust. Identities = 297/415 (71%), Positives = 351/415 (84%) Query: 13 SSPPSKIGAVLRVTSGNFLEQFDFFLFGFYAHYISKVFFPVDSEFASLMLTFAVFGAGFL 72 +S GA+LRVTSGNFLEQFDFFLFGFYA YI++ FFP +SEFASLMLTFAVFG+GFL Sbjct: 8 TSRAGTFGAILRVTSGNFLEQFDFFLFGFYATYIARTFFPAESEFASLMLTFAVFGSGFL 67 Query: 73 MRPLGAIILGAYIDKVGRRKGLIVTLSIMASGTVLIACVPGYTSIGLLAPALVLIGRLLQ 132 MRP+GAI+LGAYID++GRRKGL+VTL+IM GT+LIA VPGY +IGL APALVL+GRLLQ Sbjct: 68 MRPVGAIVLGAYIDRIGRRKGLMVTLAIMGCGTLLIALVPGYQTIGLAAPALVLLGRLLQ 127 Query: 133 GFSAGAELGGVSVYLAEIATPGHKGFYTAWQSASQQVAIVMAAALGYGLNQLLLPAELAA 192 GFSAG ELGGVSVYL+EIATPG+KGFYT+WQSASQQVAIV+AA +GY LN L ++ Sbjct: 128 GFSAGVELGGVSVYLSEIATPGNKGFYTSWQSASQQVAIVVAALIGYSLNITLGHDAISE 187 Query: 193 WGWRIPFLIGCVIVPFIFILRRSLQETEEFQARRHHPDIREVFDSMLKNWRTVLTGMLFV 252 WGWRIPF IGC+I+P IF+LRRSLQETE F R+H PD RE+F ++ KNWR + G L V Sbjct: 188 WGWRIPFFIGCMIIPLIFVLRRSLQETEAFLQRKHRPDTREIFATIAKNWRIITAGTLLV 247 Query: 253 AMTTTTFYLITVYTPTFGRTVLHLSAADSLLVTLLVGLSNFAWLPIGGALSDRIGRKPIL 312 AMTTTTFY ITVYTPT+GRTVL+LSA DSL+VT+LVG+SNF WLPIGGA+SDRIGR+ +L Sbjct: 248 AMTTTTFYFITVYTPTYGRTVLNLSARDSLIVTMLVGVSNFIWLPIGGAISDRIGRRAVL 307 Query: 313 VGISLLALLTAYPAMSWLVANPSFGHLLTVLLVFSFYFGMYNGAMVVALTEVMPINVRVV 372 +GI+LLAL+T +P M WL A P F + VLL FSF+FGMYNGAMV ALTEVMP+ VR V Sbjct: 308 MGITLLALITTWPVMQWLTAAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVYVRTV 367 Query: 373 GFSLAFSLSTAVFGGFTPAISTYLIDLTANKAAPGLWMSFAALCGLAATLILYRR 427 GFSLAFSL+TA+FGG TPAIST L+ LT +K++PG W+ AALCGLAAT +L+ R Sbjct: 368 GFSLAFSLATAIFGGLTPAISTALVKLTGDKSSPGWWLMCAALCGLAATAMLFVR 422 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 562 bits (1448), Expect = e-160, Method: Compositional matrix adjust. Identities = 275/420 (65%), Positives = 332/420 (79%) Query: 10 DTVSSPPSKIGAVLRVTSGNFLEQFDFFLFGFYAHYISKVFFPVDSEFASLMLTFAVFGA 69 T + SK ++ RV SGNFLE +DF ++G+YA I+ FFP D+EF SLML+ FG Sbjct: 2 HTHNPNESKARSIFRVVSGNFLEMYDFMVYGYYAKAIADTFFPADNEFLSLMLSLVTFGV 61 Query: 70 GFLMRPLGAIILGAYIDKVGRRKGLIVTLSIMASGTVLIACVPGYTSIGLLAPALVLIGR 129 GFLMRPLGA+ILGAYID+ GRR GLI+TL +MA GT+LIA VPGY +IGL AP LVLIGR Sbjct: 62 GFLMRPLGALILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIGR 121 Query: 130 LLQGFSAGAELGGVSVYLAEIATPGHKGFYTAWQSASQQVAIVMAAALGYGLNQLLLPAE 189 LLQGFSAG ELGGVSVYLAEI+TPG KGF+ +WQSASQQVA++ AA LG L+ L P E Sbjct: 122 LLQGFSAGVELGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPKE 181 Query: 190 LAAWGWRIPFLIGCVIVPFIFILRRSLQETEEFQARRHHPDIREVFDSMLKNWRTVLTGM 249 + WGWR+PFL+GC+IVPF+F++RRSLQETEEF+ R+H P + E+F SM +NWR V G Sbjct: 182 MGEWGWRVPFLVGCLIVPFLFLIRRSLQETEEFKQRKHRPALGEIFRSMGENWRLVGAGT 241 Query: 250 LFVAMTTTTFYLITVYTPTFGRTVLHLSAADSLLVTLLVGLSNFAWLPIGGALSDRIGRK 309 L V MTT +FYLIT YTPTFG++VLHLS DSL+VTL VG SNF WLP+ G++SDRIGR+ Sbjct: 242 LLVVMTTVSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIGRR 301 Query: 310 PILVGISLLALLTAYPAMSWLVANPSFGHLLTVLLVFSFYFGMYNGAMVVALTEVMPINV 369 P+L+ + L LLTAYPAM WL+A PSFG LL V L SF +G YNGAMVV LTE+MP V Sbjct: 302 PLLITFTALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPPAV 361 Query: 370 RVVGFSLAFSLSTAVFGGFTPAISTYLIDLTANKAAPGLWMSFAALCGLAATLILYRRGG 429 R GFSLA+SL+TA+FGGFTPAI+T+LI T NKA PGLW+SFAA+CGL ATLI+ + G Sbjct: 362 RTTGFSLAYSLATAIFGGFTPAIATWLIHATGNKAMPGLWLSFAAICGLVATLIVVKPAG 421 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 535 bits (1378), Expect = e-152, Method: Compositional matrix adjust. Identities = 267/410 (65%), Positives = 317/410 (77%) Query: 17 SKIGAVLRVTSGNFLEQFDFFLFGFYAHYISKVFFPVDSEFASLMLTFAVFGAGFLMRPL 76 SK A+ RV SGNFLE FDF ++G+YA I+ FFP + F SLML+ FGAGFLMRPL Sbjct: 9 SKARAIFRVVSGNFLEMFDFMVYGYYATAIAATFFPAGNAFLSLMLSLMTFGAGFLMRPL 68 Query: 77 GAIILGAYIDKVGRRKGLIVTLSIMASGTVLIACVPGYTSIGLLAPALVLIGRLLQGFSA 136 GAI+LGAYID+ GRR GLI+TL +MA GT+LIA VPGY +IGL AP LVLIGRLLQGFSA Sbjct: 69 GAIVLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLIGRLLQGFSA 128 Query: 137 GAELGGVSVYLAEIATPGHKGFYTAWQSASQQVAIVMAAALGYGLNQLLLPAELAAWGWR 196 G E GGVSVYL+EIATPG KGFY +WQS SQQVA++ AA LG L+ L P E+ WGWR Sbjct: 129 GGEPGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSPKEMGEWGWR 188 Query: 197 IPFLIGCVIVPFIFILRRSLQETEEFQARRHHPDIREVFDSMLKNWRTVLTGMLFVAMTT 256 +PFLIGC+IVPF+F +RRSL+ETEEF+ R+H P + E+ SM +NWR G L MTT Sbjct: 189 VPFLIGCLIVPFLFFIRRSLRETEEFEQRKHRPTMGELLRSMGENWRLAGAGTLLAVMTT 248 Query: 257 TTFYLITVYTPTFGRTVLHLSAADSLLVTLLVGLSNFAWLPIGGALSDRIGRKPILVGIS 316 +FYLIT YTPTFGR VLH+S DSL+VTL VG SN WLP+ G+LSDRIGR+ L+ S Sbjct: 249 VSFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMGSLSDRIGRRTPLIVFS 308 Query: 317 LLALLTAYPAMSWLVANPSFGHLLTVLLVFSFYFGMYNGAMVVALTEVMPINVRVVGFSL 376 L LLTAYPAM+WL+A PSFG LL V L SF +G YNGAM+V LTE+MP +R GFSL Sbjct: 309 ALTLLTAYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIVTLTEIMPPQLRTTGFSL 368 Query: 377 AFSLSTAVFGGFTPAISTYLIDLTANKAAPGLWMSFAALCGLAATLILYR 426 A+SL+TA+FGGFTPAI+T LI T NKA PGLW+SFAA+CGL ATL + + Sbjct: 369 AYSLATAIFGGFTPAIATGLIHATGNKAMPGLWLSFAAICGLVATLTVVK 418 >PA5476 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 429 Score = 491 bits (1263), Expect = e-138, Method: Compositional matrix adjust. Identities = 272/418 (65%), Positives = 327/418 (78%) Query: 12 VSSPPSKIGAVLRVTSGNFLEQFDFFLFGFYAHYISKVFFPVDSEFASLMLTFAVFGAGF 71 ++S SK A+ RV SGNFLE +DF ++GFYA I+K FFP D+ FASLML+ A FGAGF Sbjct: 1 MASNKSKGVAIFRVVSGNFLEMYDFMVYGFYATAIAKTFFPGDNPFASLMLSLATFGAGF 60 Query: 72 LMRPLGAIILGAYIDKVGRRKGLIVTLSIMASGTVLIACVPGYTSIGLLAPALVLIGRLL 131 LMRPLGA+ LGAYID+ GRR+GLI+TL +MA GT+LIA VPGY ++G+ AP LVL GRLL Sbjct: 61 LMRPLGAVFLGAYIDRHGRRQGLIITLGLMAMGTLLIAFVPGYATLGVAAPLLVLFGRLL 120 Query: 132 QGFSAGAELGGVSVYLAEIATPGHKGFYTAWQSASQQVAIVMAAALGYGLNQLLLPAELA 191 QGFSAG ELGGVSVYL+EIATPG KGF+ +WQSASQQVA+V A LG LNQ L P ++ Sbjct: 121 QGFSAGVELGGVSVYLSEIATPGRKGFFVSWQSASQQVAVVFAGLLGVLLNQWLSPQDMG 180 Query: 192 AWGWRIPFLIGCVIVPFIFILRRSLQETEEFQARRHHPDIREVFDSMLKNWRTVLTGMLF 251 WGWR+PF IGC+IVP +F++RRSL+ET EF+AR H P + +V S+ +N+ VL G Sbjct: 181 EWGWRVPFFIGCLIVPALFVIRRSLEETPEFEARTHRPSLSQVLRSIGQNFGVVLAGTAM 240 Query: 252 VAMTTTTFYLITVYTPTFGRTVLHLSAADSLLVTLLVGLSNFAWLPIGGALSDRIGRKPI 311 V MTT +FYLIT YTPTFG+ L LS DSLLVT+ +GLSNF WLP+ GA SDRIGRKP+ Sbjct: 241 VVMTTVSFYLITAYTPTFGKNELQLSDLDSLLVTMCIGLSNFIWLPVMGAFSDRIGRKPL 300 Query: 312 LVGISLLALLTAYPAMSWLVANPSFGHLLTVLLVFSFYFGMYNGAMVVALTEVMPINVRV 371 L+G S LALLTAYPA+SWLV PSF LL V L SF + YNGAMVVALTEVMP +VR Sbjct: 301 LLGASALALLTAYPALSWLVREPSFAGLLGVELWLSFLYSSYNGAMVVALTEVMPADVRT 360 Query: 372 VGFSLAFSLSTAVFGGFTPAISTYLIDLTANKAAPGLWMSFAALCGLAATLILYRRGG 429 GFSLA+SL+TA FGGFTPA+ T+LI N+AAPG+W+S AAL GL ATL+L+RR G Sbjct: 361 TGFSLAYSLATATFGGFTPAVCTWLIHTLDNRAAPGIWLSGAALLGLLATLVLFRRRG 418 >RSp0536 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 441 Score = 258 bits (660), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 167/426 (39%), Positives = 232/426 (54%), Gaps = 10/426 (2%) Query: 13 SSPPSKIGAVLRVTSGNFLEQFDFFLFGFYAHYISKVFFPVDSEFASLMLTFAVFGAGFL 72 +S P + AV GN E FDF L+GF+A I+ V FP + F +L+L A FG GF+ Sbjct: 13 TSLPRQRHAVATAILGNAFEWFDFTLYGFFAPVIATVLFPSANPFTALLLAIATFGVGFV 72 Query: 73 MRPLGAIILGAYIDKVGRRKGLIVTLSIMASGTVLIACVPGYTSIGLLAPALVLIGRLLQ 132 RPLG I+LG Y D+ GRR L ++ +MA GT LIA P Y G+ AP + +I RLLQ Sbjct: 73 TRPLGGIVLGIYADRRGRRPALALSALLMALGTALIAIAPTYAQAGIAAPVIAVIARLLQ 132 Query: 133 GFSAGAELGGVSVYLAEIATPGHKGFYTAWQSASQQVAIVMAAALGYGLNQLLLPAELAA 192 GFSAG E+GG + YL EIA PG + FYT+W AS +AIV A LG LL L A Sbjct: 133 GFSAGGEMGGATAYLNEIAPPGKRAFYTSWIQASVGLAIVCGAMLGTLATSLLDAEALRA 192 Query: 193 WGWRIPFLIGCVIVPFIFILRRSLQETEEF-----QARRHHPDIREVFDSMLKNWRTVLT 247 WGWRIPF +G +I P +++R L ET F +AR P + + + ++ R VL Sbjct: 193 WGWRIPFALGVLIGPIGYVIRSRLDETPAFARAATEARADSP----LLEVVRRHRRAVLI 248 Query: 248 GMLFVAMTTTTFYLITVYTPTFGRTVLHLSAADSLLVTLLVGLSNFAWLPIGGALSDRIG 307 G V + T Y++ Y T+ VL L ++ ++ G++ P+ G L+DR+G Sbjct: 249 GASIVILWTVCTYVLLFYMQTYAIHVLKLPSSAGFAGSMASGVTMMLTAPLFGWLADRLG 308 Query: 308 RKPILVGISLLALLTAYPAMSWLVANPSFGHLLTVLLVFSFYFGMYNGAMVVALTEVMPI 367 + +L G +L L+ AYP ++L P+ G L+ V +VF Y G + VA ++ P Sbjct: 309 YQRVLSGAALAILVLAYPLYAYLNHAPAAGTLIGVQIVFGLLSAAYTGPIPVAFADLFPT 368 Query: 368 NVRVVGFSLAFSLSTAVFGGFTPAISTYLIDLTANKAAPGLWMSFAALCGLAATLILYRR 427 V G S A++L+ + GGF P T+L AP L++ AAL L TL L R Sbjct: 369 KVLSTGLSTAYNLTVMLIGGFAPFYLTWLSHAFDPMLAPVLYVMVAALVSLIGTLWL-RA 427 Query: 428 GGAARD 433 A R Sbjct: 428 AAADRS 433