BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0291.p (298 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGl2015 [K] COG0583 Transcriptional regulator Atu Agrobacterium ... 324 1e-88 PA3587 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 239 4e-63 VC1706 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae 223 5e-58 STM3964 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 206 5e-53 metR [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 205 8e-53 >AGl2015 [K] COG0583 Transcriptional regulator Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 295 Score = 324 bits (831), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 148/284 (52%), Positives = 209/284 (73%) Query: 10 SIVQEVEKQGSLTAAAGVLHVTQSALSHSMKKLEQQLGTDIWLREGRSLRLTQAGQYLLA 69 SI++EV++ GSLTAAA L+V+QSALSH+++KLE + G +W ++GR+LRLT AG+Y+L Sbjct: 8 SILREVDRMGSLTAAAERLNVSQSALSHTIRKLEDRYGVAMWEKDGRNLRLTDAGRYILT 67 Query: 70 VANRVLPQLNLAEERLQQFAQGERGALRIGMECHPCYQWLLKVVSPYLAAWPDVDVDVKQ 129 +A RVLPQ+ AE L + G+RG+L+IGMECHPC+QWL+ V PYL WPDV +++ Sbjct: 68 LAQRVLPQIERAENVLSDYRHGQRGSLKIGMECHPCHQWLMSVTKPYLMEWPDVGLELTT 127 Query: 130 KFQFGGIGALFGYEIDLLVTPDPLDKPGLVFEPVFDYEQVLVVAGGHKLAKEEYVKPKQL 189 F FGG+ AL GYEID+L+TPDP++ G+ + PVFDYE VL V H LA + + +P L Sbjct: 128 SFAFGGVAALAGYEIDILITPDPIEMAGVHYLPVFDYELVLAVPVDHPLALKRHAEPADL 187 Query: 190 SNEVLVTYPVPVDRLDIYSMFLTPAGITPKRHKPIETTDIMLQMVASGRGVAALPRWLVL 249 +E L TYPVP +RLD++S FL PA P+ H+ IETT++MLQ+VA+GRGV+A+P WLV Sbjct: 188 LDETLFTYPVPPERLDVFSQFLVPANCRPRHHRNIETTEMMLQLVAAGRGVSAIPDWLVR 247 Query: 250 EYADKMDVVPVRLGKNGIAKHIFLGARETDVSIDYLRAFIEQAK 293 A + V VR+G++GI K I LG R+ D ++D++ F+E ++ Sbjct: 248 REAAALGVRAVRIGQSGIQKSIHLGLRDGDDTVDFIAGFLETSR 291 >PA3587 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 306 Score = 239 bits (611), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 118/292 (40%), Positives = 177/292 (60%) Query: 7 KSTSIVQEVEKQGSLTAAAGVLHVTQSALSHSMKKLEQQLGTDIWLREGRSLRLTQAGQY 66 + + + + SL AA LH+TQSALSH K+LE++LG +++R+ + +R T AG Sbjct: 5 RHLKTLHALREADSLVEAAERLHLTQSALSHQFKELEERLGMQLFVRKTKPVRFTSAGLR 64 Query: 67 LLAVANRVLPQLNLAEERLQQFAQGERGALRIGMECHPCYQWLLKVVSPYLAAWPDVDVD 126 LL +A+ +LPQL AE L + A G G L + +ECH C+QWL+ + + AWP+V++D Sbjct: 65 LLQLADSLLPQLRTAERDLARLAGGTAGRLHMAIECHSCFQWLMPTIDQFRDAWPEVELD 124 Query: 127 VKQKFQFGGIGALFGYEIDLLVTPDPLDKPGLVFEPVFDYEQVLVVAGGHKLAKEEYVKP 186 + F F + AL ++DL+VT DP++ PG+ + P+F YE +L VA H LA YV P Sbjct: 125 LASGFSFAPLPALARGDLDLVVTADPVELPGITYVPLFTYEALLAVANQHALAGRPYVVP 184 Query: 187 KQLSNEVLVTYPVPVDRLDIYSMFLTPAGITPKRHKPIETTDIMLQMVASGRGVAALPRW 246 + L E L+TYPV DRLD+++ FL PA + P + + E T +M+Q+VASGRGV LP W Sbjct: 185 EDLERETLITYPVERDRLDVFTRFLDPADVEPAQVRIAELTVMMMQLVASGRGVCCLPNW 244 Query: 247 LVLEYADKMDVVPVRLGKNGIAKHIFLGARETDVSIDYLRAFIEQAKGPATA 298 + EY+ + V RLG+ G+ +F R ++R F+ AK + A Sbjct: 245 ALHEYSSRGYVTARRLGEKGLYCTLFAAIRTDMFDAPFMRDFLLTAKDTSFA 296 >VC1706 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae Length = 305 Score = 223 bits (567), Expect = 5e-58, Method: Compositional matrix adjust. Identities = 108/275 (39%), Positives = 171/275 (62%), Gaps = 1/275 (0%) Query: 19 GSLTAAAGVLHVTQSALSHSMKKLEQQLGTDIWLREGRSLRLTQAGQYLLAVANRVLPQL 78 GSLTA A LH+TQSALSH +K LE ++G ++LR+ R +R T G+ LL +A+ +LP++ Sbjct: 17 GSLTATATSLHLTQSALSHQIKDLEARIGGQLFLRKTRPVRFTAEGEILLRLADDILPKM 76 Query: 79 NLAEERLQQFAQGERGALRIGMECHPCYQWLLKVVSPYLAAWPDVDVDVKQKFQFGGIGA 138 + AE L + G L + +ECH C+QWL+ + Y +WP+V +D F F + A Sbjct: 77 SRAENELASLKEDVNGRLHMAIECHSCFQWLMPALREYQVSWPNVALDFSSGFGFEPLPA 136 Query: 139 LFGYEIDLLVTPDPLDKPGLVFEPVFDYEQVLVVAGGHKLAKEEYVKPKQLSNEVLVTYP 198 L E+DL++T D L + + +EP+FD+E L+ A H LA + ++P+ L+++ ++TYP Sbjct: 137 LLAGELDLVITSDILPRSEVHYEPLFDFEMRLITATNHPLADKAGIEPQDLADQTMLTYP 196 Query: 199 VPVDRLDIYSMFLTPAGITPKRHKPIETTDIMLQMVASGRGVAALPRWLVLEYADKMDVV 258 V RLD+ FL PAG+ P R K + T +++QMV++G GVAALP W + E++ + + Sbjct: 197 VQKQRLDVVKHFLQPAGVEPARWKQADNTLMLVQMVSAGLGVAALPNWAISEFSRQGLIT 256 Query: 259 PVRLGKNGIAKHIFLGARETDVSIDYLRAFIEQAK 293 LGK G+ + +F R ++ YL+AF A+ Sbjct: 257 SKPLGK-GLWRRLFAATRHSEKDKRYLQAFFATAR 290 >STM3964 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 317 Score = 206 bits (524), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 114/291 (39%), Positives = 171/291 (58%), Gaps = 5/291 (1%) Query: 7 KSTSIVQEVEKQGSLTAAAGVLHVTQSALSHSMKKLEQQLGTDIWLREGRSLRLTQAGQY 66 K +Q + GSL AAA VLH TQSALSH LEQ+LG +++R+ + LR T G+ Sbjct: 5 KHLKTLQALRNSGSLAAAAAVLHQTQSALSHQFSDLEQRLGFRLFVRKSQPLRFTPQGEV 64 Query: 67 LLAVANRVLPQLNLAEERLQQFAQGERGALRIGMECHPCYQWLLKVVSPYLAAWPDVDVD 126 LL +AN+VLPQ++ A LQ + ++ LRI +ECH C QWL + + A+WP V++D Sbjct: 65 LLQLANQVLPQISRA---LQACNEPQQTRLRIAIECHSCIQWLTPALENFRASWPQVEMD 121 Query: 127 VKQKFQFGGIGALFGYEIDLLVTPDPLDKPGLVFEPVFDYEQVLVVAGGHKLAKEEYVKP 186 F AL E+DL++T D L + GL + P+FD+E LV+A H LA + + P Sbjct: 122 FTSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFDFEVRLVLAPDHPLASKTQITP 181 Query: 187 KQLSNEVLVTYPVPVDRLDIYSMFLTPAGITPKRHKPIETTDIMLQMVASGRGVAALPRW 246 + L++E L+ YPV RLD++ FL PAGI+P K ++ T +++QMVA+ G+AALP W Sbjct: 182 EDLASETLLIYPVQRSRLDVWRHFLQPAGISPLL-KSVDNTLLLIQMVAARMGIAALPHW 240 Query: 247 LVLEYADKMDVVPVRLGKNGIAKHIFLGARETDVSIDYLRAFIEQAKGPAT 297 V+E ++ +V + +G+ ++ R+ D AFI + A Sbjct: 241 -VVESVERQGLVVTKTLGDGLWSRLYAAVRDGDQRQAVTEAFIRSTRDHAC 290 >metR [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 317 Score = 205 bits (522), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 115/291 (39%), Positives = 170/291 (58%), Gaps = 5/291 (1%) Query: 7 KSTSIVQEVEKQGSLTAAAGVLHVTQSALSHSMKKLEQQLGTDIWLREGRSLRLTQAGQY 66 K +Q + GSL AAA LH TQSALSH LEQ+LG +++R+ + LR T G+ Sbjct: 5 KHLKTLQALRNCGSLAAAAATLHQTQSALSHQFSDLEQRLGFRLFVRKSQPLRFTPQGEI 64 Query: 67 LLAVANRVLPQLNLAEERLQQFAQGERGALRIGMECHPCYQWLLKVVSPYLAAWPDVDVD 126 LL +AN+VLPQ++ A LQ + ++ LRI +ECH C QWL + + WP V++D Sbjct: 65 LLQLANQVLPQISQA---LQACNEPQQTRLRIAIECHSCIQWLTPALENFHKNWPQVEMD 121 Query: 127 VKQKFQFGGIGALFGYEIDLLVTPDPLDKPGLVFEPVFDYEQVLVVAGGHKLAKEEYVKP 186 K F AL E+DL++T D L + GL + P+FDYE LV+A H LA + + P Sbjct: 122 FKSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFDYEVRLVLAPDHPLAAKTRITP 181 Query: 187 KQLSNEVLVTYPVPVDRLDIYSMFLTPAGITPKRHKPIETTDIMLQMVASGRGVAALPRW 246 + L++E L+ YPV RLD++ FL PAG++P K ++ T +++QMVA+ G+AALP W Sbjct: 182 EDLASETLLIYPVQRSRLDVWRHFLQPAGVSPSL-KSVDNTLLLIQMVAARMGIAALPHW 240 Query: 247 LVLEYADKMDVVPVRLGKNGIAKHIFLGARETDVSIDYLRAFIEQAKGPAT 297 +V + + VV LG+ G+ ++ R+ + AFI A+ A Sbjct: 241 VVESFERQGLVVTKTLGE-GLWSRLYAAVRDGEQRQPVTEAFIRSARNHAC 290