BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0237.p (376 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC0137 Non COG 92 3e-18 VC1851 Non COG 91 4e-18 BS_yuxH [T] COG3434 Predicted signal transduction protein contai... 76 1e-13 aq_478 [T] COG3434 Predicted signal transduction protein contain... 64 7e-10 >VC0137 Non COG Length = 432 Score = 91.7 bits (226), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 83/309 (26%), Positives = 148/309 (47%), Gaps = 22/309 (7%) Query: 79 LERLTKMGYGLIADGI--PPRTALFPDFIESLSLDCSAGIPADASPWLTR------MRGP 130 ++ L++ GY L D P F +++ + +D A + D + R R Sbjct: 129 VQELSQRGYLLALDDFVYSPAWERFLPYVQIVKIDIMA-MGLDKACEFVRGRLAQGSRRR 187 Query: 131 HLAENVPDPVSFDACRAEGFRWFSGEYPLLPSSNVAQKDAISRGRLVKLL---ELVSHDA 187 LAE V F R GF +F G + P + ++ +S ++ + E+ + Sbjct: 188 FLAERVETEDEFHQARHAGFTFFQGYFFSKP--EIIKQRYVSPEHVIAMQLFREVCQPEV 245 Query: 188 DVHALEGLLKQDPALSYQLFKLVSSAAFGFSAHITNFTQAINLLGRRQLQRWLQLLLYAR 247 D +E L+ QD ALSY+L + V++ + S I++F QA+ LG+ +L+ ++ L + A Sbjct: 246 DYVRVERLVAQDIALSYKLLRFVNTMSDRISVSISSFRQALVYLGQDKLRIFVSLAV-AS 304 Query: 248 FPGDESANPLLPRAAARAAMMEAMCHQIDGDRDEQDRAFIVGMFSLLDVLLTMPLRLIIE 307 + + L + RA + M + +++AF++GMFS+LD LL + ++E Sbjct: 305 YISSKKPKELYNLSLQRAQFCQLMATHTHF-KAHREQAFLIGMFSVLDALLDTSIEQLVE 363 Query: 308 PLKLPQDILDALMQRRGRLGRLLDV---VERAEYGRIPLRHTDLAAAGVTPEGYCRALIQ 364 L L D+ AL +R G LG LLD+ E+A++ + +L G E + LI+ Sbjct: 364 QLPLADDVKLALREREGPLGTLLDLEECFEKADWQGVEQHCLEL---GFDLEDVRQELIE 420 Query: 365 AYRWASKVS 373 A RW+ ++ Sbjct: 421 AQRWSQDIN 429 >VC1851 Non COG Length = 404 Score = 91.3 bits (225), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 80/304 (26%), Positives = 148/304 (48%), Gaps = 21/304 (6%) Query: 79 LERLTKMGYGLIADGIPPRT---ALFPDFIESLSLDCSAGIPADASPWLTRMRG---PHL 132 ++++ ++GY + D P A P +I + D A ++ ++R L Sbjct: 103 IKKMAQLGYKIALDDFIPSNDWKAFLP-YISIIKFDIRLVPIPKAKLFINKLRSMKIEFL 161 Query: 133 AENVPDPVSFDACRAEGFRWFSGEYPLLPSSNVAQKDAI--SRGRLVKLLELVSH-DADV 189 AE V F+ + GF +F G + P + Q+ A+ S +V+LL+ V+ + D Sbjct: 162 AEKVETYEEFEQAKQAGFHYFQGYFFSKP--EIIQRKALQPSFLTIVQLLKEVAKPEVDF 219 Query: 190 HALEGLLKQDPALSYQLFKLVSSAAFGFSAHITNFTQAINLLGRRQLQRWLQLLLYARFP 249 +E ++ +D +LSY+L V+S+A S+ I +F QA+ LG+++L++++ L+ A Sbjct: 220 REIETIVAKDISLSYKLLTFVNSSA-TVSSKIQSFRQALVYLGQQKLRKFISLVAIAS-T 277 Query: 250 GDESANPLLPRAAARAAMMEAMCHQIDGDRDEQDRAFIVGMFSLLDVLLTMPLRLIIEPL 309 D + L A RA E + ++ + F+ GMFS+LD LL L I++ + Sbjct: 278 QDSKPDYLYNLAILRARFCEMLSERVPTNI-APGTGFLTGMFSVLDSLLDQSLDSIVKEM 336 Query: 310 KLPQDILDALMQRRGRLGRLL---DVVERAEYGRIPLRHTDLAAAGVTPEGYCRALIQAY 366 + +++ AL Q G LG++L E A++G++ T A + E I+A Sbjct: 337 PIEEEVKQALTQGSGTLGQILALNKAYEMADWGQV---VTLGQALNLPNEAPTECYIEAV 393 Query: 367 RWAS 370 +W + Sbjct: 394 KWTA 397 >BS_yuxH [T] COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains Bsu Bacillus subtilis Length = 409 Score = 76.3 bits (186), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 73/293 (24%), Positives = 131/293 (44%), Gaps = 19/293 (6%) Query: 60 QLILRVPVEYCADPARQPLLERLTKMGYGLIAD---GIPPRTA----LFPDFIESLSLDC 112 QL++ + + PA + L KMGY L D I P+ +I+ L +D Sbjct: 84 QLVIEILEDIPITPALISRCKELKKMGYMLALDDFYAINPQDEDLLEKLMSYIDILKIDF 143 Query: 113 SAGIPADASPWLTRM--RG-PHLAENVPDPVSFDACRAEGFRWFSGEY---PLLPSSNVA 166 + L RG LAE V + +GF+ F G + P + S + Sbjct: 144 LKTTRMERRTILQTYGCRGLIFLAEKVETRKEYKQAVQDGFQLFQGYFFSEPRIISGHDL 203 Query: 167 QKDAISRGRLVKLLELVSHDADVHALEGLLKQDPALSYQLFKLVSSAAFGFSAHITNFTQ 226 S L+ EL ++ + +++D +LSYQ+ K ++S+ S I + Q Sbjct: 204 STHFYSYYELLN--ELSKEQPNIKRVTEYIERDLSLSYQILKFLNSSHSRLSQKIESIQQ 261 Query: 227 AINLLGRRQLQRWLQLLLYARF--PGDESANPLLPRAAARAAMMEAMCHQIDGDRDEQDR 284 AI LLG +++RW+ +L + G S + ++ + RA + E + + R + Sbjct: 262 AIMLLGFNEIKRWIYILSFKDLSRKGHSSKHEIIKISLIRAKLCELLARK--TSRPQPAS 319 Query: 285 AFIVGMFSLLDVLLTMPLRLIIEPLKLPQDILDALMQRRGRLGRLLDVVERAE 337 ++GMFSL+D LL + I++ L L ++ AL+ + ++L++V+ E Sbjct: 320 YMLIGMFSLIDTLLHREIEEIVQELPLKDEVGQALLGHQNDYYQMLELVKLIE 372 >aq_478 [T] COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains Aae Aquifex aeolicus Length = 411 Score = 63.5 bits (153), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 43/163 (26%), Positives = 86/163 (52%), Gaps = 5/163 (3%) Query: 176 LVKLLELVSHDADVHALEGLLKQDPALSYQLFKLVSSAAFGFSAHITNFTQAINLLGRRQ 235 L++LL +S + + +++ D L+ + + V+SA F I + A++ +G Sbjct: 208 LLRLLNAISIARSLKEIADIIETDVGLAVKFLQFVNSAYFARRKKIESLEHAVSFVGMEN 267 Query: 236 LQRWLQLLLYARFPGDESANPLLPRAA-ARAAMMEAMCHQIDGDRDEQDRAFIVGMFSLL 294 +++++ L+ F E NP L R + RA + E + ++ + E +AF+VG+FSLL Sbjct: 268 IKKFVILVSMNEFLKVE--NPELWRKSLTRAFIAEELTNRYSPEVSE--KAFLVGLFSLL 323 Query: 295 DVLLTMPLRLIIEPLKLPQDILDALMQRRGRLGRLLDVVERAE 337 D +L + + + L + ++++ A + L +LL+VV R E Sbjct: 324 DKILEVDIPTFLRELNVDEEVVKAFEDKGSSLHKLLEVVSRLE 366