BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0202.p (749 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0875 [S] COG1289 Predicted membrane protein Pae Pseudomonas ae... 559 e-158 PA3893 [S] COG1289 Predicted membrane protein Pae Pseudomonas ae... 535 e-151 BMEII0531 [S] COG1289 Predicted membrane protein Bme Brucella me... 178 4e-44 mlr0902 Non COG 166 2e-40 PA3305 [S] COG1289 Predicted membrane protein Pae Pseudomonas ae... 166 3e-40 >PA0875 [S] COG1289 Predicted membrane protein Pae Pseudomonas aeruginosa Length = 731 Score = 559 bits (1440), Expect = e-158, Method: Compositional matrix adjust. Identities = 308/719 (42%), Positives = 430/719 (59%), Gaps = 11/719 (1%) Query: 16 PAPQSF---GRQLHDAAADWWQTDFPNWIYVFKMVFAGLLALGIGYALDLESPRSGLITV 72 PAP +F +L A +W ++D W++VFK + LAL + Y L+L P + L+TV Sbjct: 14 PAPLAFFPSPDELRRALLEWARSDGVAWVFVFKALLTASLALWLAYHLELPQPSTVLVTV 73 Query: 73 FIVMQPQSGMILAKSFYRVIGTLVGSAAVVVFVGLFAQTPELFLLATACWIGLCTVGSAH 132 FIVMQ QSG +LAKSFYR++GTL+G + +V + LFAQ LFL A W+GLCT G+A Sbjct: 74 FIVMQTQSGQVLAKSFYRIVGTLIGLSVMVTLIALFAQERVLFLACLALWVGLCTAGAAR 133 Query: 133 NRNFRSYGFVLSGYTVALIGIPAALNPALTFDSVMTRVTEITVGIVCAGVVSALVFPQAS 192 R+FR Y VL+GYT +IGIPA +P F + + RV EI++GI+C G VSA+ PQ S Sbjct: 134 YRDFRGYACVLAGYTATMIGIPATAHPEGAFMAALWRVLEISLGILCTGTVSAIFLPQTS 193 Query: 193 APGLVRIIRGRFTAFVDLIGNTLGGSADRKALEATNARFVGDIIGLEALRSSAIFEDPEI 252 L + GRF F L GS D + +ARFV +GLE LRS+ FEDP + Sbjct: 194 GAALRNTLYGRFRDFAGFAAEGLQGSLDGERFGELSARFVAQSVGLENLRSATTFEDPHM 253 Query: 253 RLRSGRLTRMNSEFMALSTRVHALHQLMNRLHDSRNPSAQLVIDAISPYFREVQPLLTRS 312 RLRSGRL R+N+EFM +++R H LH+L+ RL R AQ V++ ++P E+ LL Sbjct: 254 RLRSGRLIRLNNEFMVMTSRFHGLHRLLERL---RGRGAQNVLEVLAPCLAELAGLLA-P 309 Query: 313 GGEPVMTAIDAADAALKLESYKQELPRRVRATRDAHTRSQELDDDAVLDFDTASELLYRV 372 E T DAA A ++E+YK EL + +R R + ++D +LDF+TA+EL +R Sbjct: 310 IRERTPTDADAARLAERIEAYKPELMQNIRQARQRLVEQRPGEND-LLDFNTAAELAFRF 368 Query: 373 IEELHAYTLTYASLVQRRHEREQWEHVYAPKTSMVTASIAGARAAITLIGLSTFWILSGW 432 ++LH Y LT+ASL + H REQW+ + + + V A +AGAR+A+ + L TFWI + W Sbjct: 369 TDDLHNYALTHASLAEHHHAREQWKESFVARANPVAALVAGARSALMIGLLGTFWIQTSW 428 Query: 433 PSGDVAALNAAAFCAITSAAPDPAKATRTVTMGVALAVVLGYFYTFHIVPQLDGFWMLAA 492 P G AL A A++S +P+P + + +T+G G F +++P +DGF ML Sbjct: 429 PHGGTFALTAVLISALSSTSPNPGRLSLQLTLGTLAGACTGLFVLLYLLPHVDGFPMLLC 488 Query: 493 ALTPVLMLAVLLTTKPTLAGYGLGICIFFPFVAVPDNLAHFNAAGYLNESIALMLSLVVT 552 L PV + LL +P GYG+G+ ++F F ++P N+A ++A + NE +AL+LS+V+ Sbjct: 489 CLLPVFAVGALLLWRPQWNGYGVGLLVWFCFASLPANMARYDALAFFNEYLALLLSMVLA 548 Query: 553 TVAFMVLLPPTTNWTVRHLEKQLRKQVVQACFGKLAHLALQFESGTRDLMHQITMLTGSR 612 TVA MV+LPP W + LE LR++VV A GK L FESGTRDL++Q + R Sbjct: 549 TVAAMVILPPNRPWMWKRLEHDLRERVVFAISGKSKGLVSGFESGTRDLLNQAYTFSAGR 608 Query: 613 PALRKDAFGWMFATLEIGHAIIELRTELHGIRSGNPGLLSPAAYAALDRLR-EALPALFR 671 P +++ GWMF LE+G AIIELR E + P A+ RL AL LF Sbjct: 609 PDVQRRLLGWMFLVLEVGQAIIELRLEQQRL-PQEPCYAERTAWRRAIRLMGRALIRLFL 667 Query: 672 QPTPATLAAVLDANNRTIAEVQQAIGPHYRERSERHRLQRTLSYLHFIRTALLDPQSPL 730 QP P+ L A N+ I V+ A P + + L+R LSYLHFIR+ALLDPQSPL Sbjct: 668 QPGPSNRQRALHAVNQAIMAVRAAPEPRA-PQFDTSPLRRVLSYLHFIRSALLDPQSPL 725 >PA3893 [S] COG1289 Predicted membrane protein Pae Pseudomonas aeruginosa Length = 731 Score = 535 bits (1377), Expect = e-151, Method: Compositional matrix adjust. Identities = 308/728 (42%), Positives = 433/728 (59%), Gaps = 18/728 (2%) Query: 7 SATSATATTPAPQSFGRQLHDAAADWWQTDFPNWIYVFKMVFAGLLALGIGYALDLESPR 66 S SA P+ + R L A+W ++D WIYVFK++ A L L + L+L P Sbjct: 2 SGRSAGFALPSRDEWRRAL----AEWARSDGATWIYVFKVLCAAFLTLWLAMRLELPQPS 57 Query: 67 SGLITVFIVMQPQSGMILAKSFYRVIGTLVGSAAVVVFVGLFAQTPELFLLATACWIGLC 126 + ITVFIVMQPQSG + AKSFYR++GTLVG + +V + LFAQ LFLL++A WIGLC Sbjct: 58 TATITVFIVMQPQSGQVFAKSFYRILGTLVGLSVMVTLIALFAQERVLFLLSSAIWIGLC 117 Query: 127 TVGSAHNRNFRSYGFVLSGYTVALIGIPAALNPALTFDSVMTRVTEITVGIVCAGVVSAL 186 T G+A R+FRSY VL+GYT LIGIPA +P F + RV EI++ I+C+GVVSA+ Sbjct: 118 TAGAARYRDFRSYACVLAGYTATLIGIPATSHPEGAFMQAIWRVLEISLAILCSGVVSAV 177 Query: 187 VFPQASAPGLVRIIRGRFTAFVDLIGNTLGGSADRKALEATNARFVGDIIGLEALRSSAI 246 + PQ ++ + + RF F + ++L G R+ E++N F +GLE +R+++ Sbjct: 178 IMPQTTSAAMRNALYVRFGLFAAFVLDSLRGVGGRERFESSNVAFAAQAVGLETMRAASA 237 Query: 247 FEDPEIRLRSGRLTRMNSEFMALSTRVHALHQLMNRLHDSRNPSAQLVIDAISPYFREVQ 306 FEDP +RLR+GRL R++SEFMA++TR HALHQL+ RL R + V++A P E+ Sbjct: 238 FEDPHMRLRNGRLIRLSSEFMAMNTRFHALHQLLERL---RAQGSTQVLEAFEPCLEEIT 294 Query: 307 PLLTRSGGEPVMTAIDAADAALKLESYKQELPRRVRATRDAHTRSQELDDDAVLDFDTAS 366 LL G V T DA A +L ++ L R+R R ++E ++A LDF+TA+ Sbjct: 295 GLLEEIRGRAV-TDHDAERFAQRLADCRERLMARIRQAR-GELLAREPGEEARLDFNTAA 352 Query: 367 ELLYRVIEELHAYTLTYASLVQRRHEREQWEHVYAPKTSMVTASIAGARAAITLIGLSTF 426 ELLYR EE+H Y LT+ASL RHEREQW+ + K + V A++AG R + ++ F Sbjct: 353 ELLYRFAEEMHDYALTHASLAAHRHEREQWKDAFTAKANAVAAAVAGMRTGLMILLFGCF 412 Query: 427 WILSGWPSGDVAALNAAAFCAITSAAPDPAKATRTVTMGVALAVVLGYFYTFHIVPQLDG 486 WI S WPSG ALNA A A+ SAAP+P K + +G A +LG+ F + P +DG Sbjct: 413 WIYSTWPSGGTFALNAVAVSALASAAPNPKKVAMQMAIGTMAAALLGFSEMFFVYPHIDG 472 Query: 487 FWMLAAALTPVLMLAVLLTTKPTLAGYGLGICIFFPFVAVPDNLAHFNAAGYLNESIALM 546 F +L L PV L ++++P AGYGLG+ +FF F +VP NL ++ A +NE IAL+ Sbjct: 473 FPLLCLVLAPVFALGAFISSRPQWAGYGLGLLVFFCFGSVPANLTVYDPAHVINEYIALI 532 Query: 547 LSLVVTTVAFMVLLPPTTNWTVRHLEKQLRKQVVQACFGKLAHLALQFESGTRDLMHQIT 606 LS++++ A V+LPP + W + LE+ LR +VV A G+ L FESGTRDL++Q Sbjct: 533 LSMLLSAAAAAVILPPNSAWLWKRLERDLRMRVVFAISGRSRGLGSAFESGTRDLLNQAY 592 Query: 607 MLTGSRPALRKDAFGWMFATLEIGHAIIELRTELHGIRSGNPGLLSPAAY-AALDRLREA 665 + RP +++ WMF LE+GHAIIELR E + P + A+ + A Sbjct: 593 GVAAGRPDVQRGLLRWMFLVLEVGHAIIELRREQERL-PDEPCYAEAMPWRQAIRAMGRA 651 Query: 666 LPALFRQPTPATLAAVLDANNRTI---AEVQQAIGPHYRERSERHRLQRTLSYLHFIRTA 722 L LF +P L L A ++ I + PH+ + L+R SYLHFIR++ Sbjct: 652 LIRLFVRPGAENLERALAAVDQAIHAARHTDEPCAPHF----DSSPLRRVRSYLHFIRSS 707 Query: 723 LLDPQSPL 730 LL P SPL Sbjct: 708 LLAPTSPL 715 >BMEII0531 [S] COG1289 Predicted membrane protein Bme Brucella melitensis Length = 698 Score = 178 bits (451), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 175/686 (25%), Positives = 283/686 (41%), Gaps = 77/686 (11%) Query: 37 FPNWIYVFKMVFAGLLALGIGYALDLESPRSGLITVFIVMQPQSGMILAKSFYRVIGTLV 96 F + ++ K A +LAL IG +L +P + V+IV P SG +K FYR+IGT++ Sbjct: 11 FWDVVFSLKTFAAAMLALWIGLMANLPNPYWSVAAVYIVAHPLSGATTSKGFYRLIGTII 70 Query: 97 GSAAVVVFVGLFAQTPELFLLATACWIGLCTVGSAHNRNFRSYGFVLSGYTVALIGIPAA 156 G A VVFV +PE+ LA W+GLC V S + RSY F+L+GYTVA+ Sbjct: 71 GGAVTVVFVPHLVNSPEILTLAIGLWMGLCLVISLLDGTPRSYLFMLAGYTVAIASFAVV 130 Query: 157 LNPALTFDSVMTRVTEITVGIVCAGVVSALVFPQASAPGLVRIIRGRFTAFVDLIGNTLG 216 P TFD + RV EI VGI+CA VV+ LVF + S P LV I L ++ Sbjct: 131 QAPETTFDYALGRVEEIAVGIICAAVVNRLVFSRHSGPVLVGRIDNWLRDGSKLAVASMR 190 Query: 217 GSADRKALEATNARFVGDIIGLEALRSSAIFEDPEIRLRSGRLTRMNSEFMALSTRVHAL 276 G D R D + L L + ++ IR + L + +A+ + +L Sbjct: 191 GEGDSPEFRRDRQRLAADTLELRNLTTHVAYDTSSIRNVAPLLHVLQQRMVAVLPIISSL 250 Query: 277 HQLM----NRLHDSRNPSAQLVIDAISPYFREVQPLLTRSGGEPVMTAIDAADAALKLES 332 H ++ +P+ Q ++D + + + + LT + I+ D Sbjct: 251 HDVLLLKPGEGEKPWHPAVQQLLDEVCDWLQSGEN-LTEERRTVFLRLIEEID------- 302 Query: 333 YKQELPRRVRATRDAHTRSQELDDDAVLDFDTASELLYRVIEELHAYTLTYA-------- 384 R +RDA T + +L F+ ++ + R + ++ LT Sbjct: 303 ---------RHSRDASTWGE------LLPFNLSARI--RDLVQIWNDCLTLKQDISSGSR 345 Query: 385 -SLVQRRHEREQWEHVYAPKTSMVTASIAGARAAITLIGLSTFWILSGWPSGDVAALNAA 443 SL RR++ M A ++G + + + W+ SGW G AA+ A Sbjct: 346 HSLRWRRYDAHLKGRPMHRDYGM--ALLSGFSSFLATCVATALWVASGWAQGSAAAMMAG 403 Query: 444 AFCAITSAAPDPAKATRTVTMGVALAVVLGYFYTFHIVPQLDGFWMLAAALTPVLMLAVL 503 FC I + DP R + + + + + F ++P ++GF L L L+ A + Sbjct: 404 IFCCIFATMDDPVPVIRKFNWLLMVVIAAAFVFEFALLPLVNGFMPLVLVLGLFLVPAGM 463 Query: 504 LTTKPTLAGYGLGICIFFPFVAVPDNLAHFNAAGYLNESIALMLSLVVTTVAFMVLLPPT 563 L P+ G+ +C+ P + + + + + N ++A +L +V+ V ++ Sbjct: 464 LLVIPSQFLLGMVLCVNLPNMLMLQSHLTLDFPSFANANLATVLGIVIAAVVTSIVRSVG 523 Query: 564 TNWTVRHLEKQLRKQVVQACFGKLAHLALQFESGTRDLMHQITMLTGSRPALRKDAFGWM 623 W+VR L K +V A + + E R L+ I D G M Sbjct: 524 AEWSVRRLVKAGWSDIVLATERRPGR--YRREHMNRLLLRMI------------DRIGMM 569 Query: 624 FATLE-IGHAIIELRTELHGIRSGNPGLLSPAAYAALDRLREALPALFRQPTPATLAAVL 682 L I A + L +R+G + L + R LPA R+ Sbjct: 570 APRLALIPDADVAKVDLLRDLRNGMNTI-------DLQQYRAKLPAPCRE---------- 612 Query: 683 DANNRTIAEVQQAIGPHYRERSERHR 708 + EV +G HYR S + R Sbjct: 613 -----AVDEVLDGVGAHYRALSNKTR 633 >mlr0902 Non COG Length = 688 Score = 166 bits (420), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 166/620 (26%), Positives = 271/620 (43%), Gaps = 43/620 (6%) Query: 39 NWIYVFKMVFAGLLALGIGYALDLESPRSGLITVFIVMQPQSGMILAKSFYRVIGTLVGS 98 +WI+ + V AGL+AL YAL L+ P+ ++TVFIV QP +GM+LAK FYR++GTL G Sbjct: 24 DWIFALRTVSAGLIALLAAYALKLDHPQWAMMTVFIVAQPVAGMVLAKGFYRLLGTLAGG 83 Query: 99 AAVVVFVGLFAQTPELFLLATACWIGLCTVGSAHNRNFRSYGFVLSGYTVALIGIPAALN 158 A + +F P + + A WIG+CT S+ RN +YG L+GYT +IG+PA Sbjct: 84 LAAIGITTVFGTNPWVLVTVLAVWIGICTFVSSLLRNPEAYGAALAGYTAMIIGLPAFGQ 143 Query: 159 PALTFDSVMTRVTEITVGIVCAGVVSALVFPQASAPGLVRIIRGRFTAFVDLIGNTLGG- 217 P L D + R EI +GIVCAGV S L+ P+ ++ ++ ++ +DL G Sbjct: 144 PHLVVDLAVARCAEIVLGIVCAGVTSRLILPKLASDAIISRLK---RCILDLATYAAGAF 200 Query: 218 -SADRKALEATNARFVGDIIGLEALRSSAIFEDPEIRLRSGRLTRMNSEFMALSTRVHAL 276 D L A + + V D L +R+ A E P R+ + R + ++ + AL Sbjct: 201 SGGDTATLSALHRKLVADTQTLGEMRAYARLEAPSFAPRAHPVRRTIGQLLSALSAARAL 260 Query: 277 HQLMNRLHDSRNPSAQLVIDAISPYFREVQPLLTRSGGEPVMTAIDAADAALKLESYKQE 336 H H + +A + P ++Q L+ +P A+D D A +E Sbjct: 261 HS-----HAAPKNAALI------PVRSQLQALVGDLATKP--GALD--DTAPWVEQL-DA 304 Query: 337 LPRRVRATRDAHTRSQELDDDAV---------LDFDTASELLYRVIEELHAYTLTYASLV 387 + R R DA S + DD V DF +E L +V+ L A Sbjct: 305 ISARARQLPDA---SIDQGDDRVGTITRLTIAADF---AEALKQVLRGLDALRAPVTGTG 358 Query: 388 QRRHEREQWEHVYAPKTSMVTASIAGARAAITLIGLSTFWILSGWPSGDVAALNAAAFCA 447 + + H P AS RAA+ + ++ FW+ + W + A + Sbjct: 359 RAGRQPALVVHRDYPG-----ASRNAVRAALATLLVAAFWLTTKWSEAAGTVILVAVVSS 413 Query: 448 ITSAAPDPAKATRTVTMGVALAVVLGYFYTFHIVPQLDGFWMLAAALTPVLMLAVLLTTK 507 + +A PDP + + G LA+ + +P L GF + P+L+ L Sbjct: 414 LFAARPDPVQVSWGFFKGTLLALPFAFLIGQIALPALPGFGWFVLFVVPILVPTALGMAN 473 Query: 508 PTLAGYGLGICIFFPFVAVPDNLAHFNAAGYLNESIALMLSLVVTTVAFMVLLPPTTNWT 567 P G I F P ++ + S ++++ +++ F+V+LP Sbjct: 474 PRYVGIATAFAINFLAFLSPHQAMTYDPGPFFAGSASVLVGILLAIGVFIVVLPADPWLA 533 Query: 568 VRHLEKQLRKQVVQACFGKLAHLALQFESGTRDLMHQITMLTGSRPALRKDAFGWMFATL 627 + + +R+ + + C + FES D ++Q+ L + G A + Sbjct: 534 ANRIVRAMREDLARLCLHERVPRRSAFESLAYDRINQLMPLVQNSGRKGDAVLGGGVAAV 593 Query: 628 EIGHAIIELR--TELHGIRS 645 +G I+ LR ++ H I S Sbjct: 594 TVGLEILRLRGASQNHAIPS 613 >PA3305 [S] COG1289 Predicted membrane protein Pae Pseudomonas aeruginosa Length = 664 Score = 166 bits (419), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 94/222 (42%), Positives = 127/222 (57%), Gaps = 15/222 (6%) Query: 42 YVFKMVFAGLLALGIGYALDLESPRSGLITVFIVMQPQSGMILAKSFYRVIGTLVGSAAV 101 + K + AG LAL + DLE P+ L+TV IV QP SGM++AK +R++GTLVG+A Sbjct: 18 FAIKTLLAGGLALWCAFRFDLEQPQWALMTVLIVSQPLSGMVVAKGLFRLLGTLVGTAMS 77 Query: 102 VVFVGLFAQTPELFLLATACWIGLCTVGSAHNRNFRSYGFVLSGYTVALIGIPAALNPAL 161 V+ + LFAQ P LFLLA + W+GLCT S RN SY FVLSGYTVA+IG+PA P L Sbjct: 78 VLMIALFAQAPWLFLLAISLWLGLCTAASTSLRNHVSYAFVLSGYTVAIIGLPAVDQPLL 137 Query: 162 TFDSVMTRVTEITVGIVCAGVVSALVFPQASAPGLVRIIRGRFTAFVDLIGNTLGGSADR 221 F+ + R TEI +GI+CA VSA+++PQ L + + LG A R Sbjct: 138 VFEQAVARCTEICLGIICASAVSAILWPQRVEQNLDKQAHATW---------LLGMQAAR 188 Query: 222 KALEATNARFVG------DIIGLEALRSSAIFEDPEIRLRSG 257 ++ + G I+ ++A R A FE R R+G Sbjct: 189 GEIDPRQRQPQGLLNALSKIVEVDAQRDHAWFEGERGRRRAG 230 Score = 71.6 bits (174), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 67/257 (26%), Positives = 106/257 (41%), Gaps = 7/257 (2%) Query: 413 GARAAITLIGLSTFWILSGWPSGDVAALNAAAFCAITSAAPDPAKATRTVTMGVALAVVL 472 G R+A+ L+GLS +WI + WP+ A L AA C++ + + + G+ A+ Sbjct: 355 GTRSALALLGLSVYWIYTAWPAASGAMLLAAVVCSLFANRDNAVAIGLSFLRGIVYAIPA 414 Query: 473 GYFYTFHIVPQLDGFWMLAAALTPVLMLAVLLTTKPTLAGYGLGICIFFPFVAVPDNLAH 532 + ++PQ +GF +L A+ L A L P AG I F + P N Sbjct: 415 AMLVSQWLLPQWNGFPLLCLAMGVPLFFATLGMAVPVTAGTATSFAIHFIVLVAPRNQMD 474 Query: 533 FNAAGYLNESIALMLSLVVTTVAFMVL-LPPTTNWTVRHLEKQLRKQVVQACFGKLAHLA 591 +N A LN + +++ + V F +L L P W R L + + LA Sbjct: 475 YNLATLLNSAQGVLIGVGFAVVIFRLLTLRP--GWLTRRLLDATCVDLGRLTRRPLAQAE 532 Query: 592 LQFESGTRDLMHQITMLTGSRPALRKDAFGWMFATLEIGHAIIELRTELHGIRSGNPGLL 651 F D + ++ P + + L++G+ +I LR L G R G+L Sbjct: 533 NWFGGRMADRLLRLARHANLLPEQERRRWDDGLLALDLGNELIHLRACLEGAR----GVL 588 Query: 652 SPAAYAALDRLREALPA 668 A L L E L A Sbjct: 589 RKARDRFLGELGELLEA 605