BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0195.p (462 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2322 [GE] COG2610 H+/gluconate symporter and related permeases... 341 2e-93 SA2293 [GE] COG2610 H+/gluconate symporter and related permeases... 312 9e-85 RSp1189 Non COG 308 2e-83 YPO3954 [GE] COG2610 H+/gluconate symporter and related permease... 294 4e-79 BS_gntP [GE] COG2610 H+/gluconate symporter and related permease... 288 2e-77 >PA2322 [GE] COG2610 H+/gluconate symporter and related permeases Pae Pseudomonas aeruginosa Length = 450 Score = 341 bits (875), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 199/453 (43%), Positives = 289/453 (63%), Gaps = 20/453 (4%) Query: 13 QDTRLLLSVLIALIAIVVLISVLKIAPFLSILLGTFIAGTGGPGXAGLPLEKIASSFSKG 72 D LLL L+ +I ++VLI+ K+ PF+++++ G +G+P+EKI SF G Sbjct: 6 HDAYLLLDALVTIIGLIVLITRFKVHPFIALIIAAGFLGL----TSGMPVEKIVKSFQDG 61 Query: 73 AGSILGEAGIIIALGAMLGALMADSGAADKIVTTLLRYAKGAAIPWMMALVALVVGLPLF 132 G +LG G+I+ALG MLG LMADSG AD+I TL+R + W M L A +VG+PLF Sbjct: 62 FGGVLGFVGVILALGTMLGKLMADSGGADQIARTLIRAFGKERVHWSMMLAAFLVGIPLF 121 Query: 133 FEVGLVMMAPIIFVMARRSQQPILRVAIPALAGMTTLHALLPPHPGPLIAVSALHADLGT 192 FE+G +++ P++F++ARRS ++++ IP LAG++ +H L+PPHPGPL+A+ AD+G Sbjct: 122 FEIGFILLIPLVFIVARRSGVSLIKIGIPLLAGLSAVHGLVPPHPGPLLAIGVFGADIGK 181 Query: 193 TMLLGFVVAIPAVILAGPLYGMWLAPRMPIGEP-----EQIGALFKGQQAPELQ--PGFL 245 T+L G +VA+P +AGPL+G ++ +P G P EQI PE Q P F Sbjct: 182 TILYGLIVALPTAAIAGPLFGALVSRYIP-GTPSAELVEQIA------HEPETQDLPSFG 234 Query: 246 PSLITILLPVVLMLGRTVAKIWVMPETTLFEM-LNFFGEPIIALTVTVLFAVVVLGWSRG 304 +L T+LLPV LML +T A + P+ F ++ G PI AL + +L A+ G++RG Sbjct: 235 VTLATVLLPVFLMLLKTFADV-AFPDGHAFRAWMDMIGHPISALLLALLVALYTFGYARG 293 Query: 305 VSRTDVGAILRKALPPIAGLLLTIGAGGGLKQALLTAGISDTITKVATGTHVPLILLAWL 364 + +L ++L P A +++ IGAGGG KQ L+ +G+ D I +A + ILLAWL Sbjct: 294 FDSKKILRLLDQSLAPTAAIVMIIGAGGGFKQMLVASGVGDVIGHLAVNAQISPILLAWL 353 Query: 365 IAVALRQATGSATVATTATAGIVAPLVASLSGTHNALMALAIGAGSVFFCHVNDAGFWMV 424 +A +R ATGSATVAT AGIV P++ + G + L+ LA GAGS+ HVNDAGFW+V Sbjct: 354 VAAVIRIATGSATVATITGAGIVVPVIDLIPGVNRELLVLATGAGSLILSHVNDAGFWLV 413 Query: 425 KEYFGLDLKQTFATWSVIQTIVSVVGLVMTLLL 457 K+YF + + +TF TW+ ++TI+SVVGLV LLL Sbjct: 414 KQYFNMSVSETFKTWTAMETILSVVGLVFILLL 446 >SA2293 [GE] COG2610 H+/gluconate symporter and related permeases Sau Staphylococcus aureus N315 Length = 452 Score = 312 bits (800), Expect = 9e-85, Method: Compositional matrix adjust. Identities = 181/448 (40%), Positives = 273/448 (60%), Gaps = 15/448 (3%) Query: 18 LLSVLIALIAIVVLISVLKIAPFLSILLGTFIAGTGGPGXAGLPLEKIASSFSKGAGSIL 77 L+SV++ ++ ++VLI K+ F+S+++ + I G+PL KI + KG GS L Sbjct: 8 LISVVLGIVILLVLIIGFKLNTFISLIITSMITAL----MLGIPLTKIMETIEKGMGSTL 63 Query: 78 GEAGIIIALGAMLGALMADSGAADKIVTTLLRYAKGAAIPWMMALVALVVGLPLFFEVGL 137 G +I LGA+LG L+AD G A +I TL++ + W M + A +VG+ LFFEVGL Sbjct: 64 GHIALIFGLGAILGKLLADGGGATRIADTLIQKFGQKHVQWAMLVAAFIVGIALFFEVGL 123 Query: 138 VMMAPIIFVMARRSQQPILRVAIPALAGMTTLHALLPPHPGPLIAVSALHADLGTTMLLG 197 V++ P++F +A+R+ +L++ +P + ++ H LPPHPGP++ L A++G +L G Sbjct: 124 VLLIPLVFTVAKRANVSVLKLGLPMVTALSVTHGFLPPHPGPVVIAKELKANVGDVLLYG 183 Query: 198 FVVAIPAVILAGPLYGMWLAPRMPI-----GEPEQIGALFKGQQAPELQPGFLPSLITIL 252 ++AIP ++AGP++ +P G+ +GA + + + PGF SL+T Sbjct: 184 MIIAIPVTLIAGPIFNKVAQKMIPSAYTREGDISALGA--QKEFTDQEMPGFGMSLLTAT 241 Query: 253 LPVVLMLGRTVAKIWVMPE--TTLFE-MLNFFGEPIIALTVTVLFAVVVLGWSRGVSRTD 309 LPV+LML T+ ++ + T LFE ++ G A+ + VLFA+V +G R Sbjct: 242 LPVILMLVSTITQLVTGHDKPTNLFESIIYMIGTAGTAMLIAVLFAIVTMGLMRKRKMNH 301 Query: 310 VGAILRKALPPIAGLLLTIGAGGGLKQALLTAGISDTITKVATGTHVPLILLAWLIAVAL 369 + + A+ PI +LL IG GG KQ L+ G+ +TI K+ GT + ILLAW++A L Sbjct: 302 IMESVTNAIYPIGMMLLIIGGGGTFKQVLIDGGVGNTIAKMFEGTEMSPILLAWIVAAVL 361 Query: 370 RQATGSATVATTATAGIVAPLVASLSGTHNALMALAIGAGSVFFCHVNDAGFWMVKEYFG 429 R A GSATVA +T GIV PL+ S S + AL+ LAIGAGSV HVNDAGFWM KEYFG Sbjct: 362 RIALGSATVAAISTTGIVLPLLQS-SDVNVALVVLAIGAGSVILSHVNDAGFWMFKEYFG 420 Query: 430 LDLKQTFATWSVIQTIVSVVGLVMTLLL 457 L +K+TF TWS+++TI+SV G++ L + Sbjct: 421 LTVKETFLTWSLLETIISVSGIIFILFI 448 >RSp1189 Non COG Length = 450 Score = 308 bits (789), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 173/422 (40%), Positives = 254/422 (60%), Gaps = 5/422 (1%) Query: 29 VVLISVLKIAPFLSILLGTFIAGTGGPGXAGLPLEKIASSFSKGAGSILGEAGIIIALGA 88 + LI+V K+ PF+++++ + + G G+P+ I +F G G+ LG +++ LG Sbjct: 21 IYLIAVRKLNPFVTLIVVSLVLGVA----VGMPMGNIVKAFETGVGNTLGHIALVVGLGT 76 Query: 89 MLGALMADSGAADKIVTTLLRYAKGAAIPWMMALVALVVGLPLFFEVGLVMMAPIIFVMA 148 MLG +MA+SG A++I TL+R W M +VA ++GLP+FFEVG V++ PI F +A Sbjct: 77 MLGKMMAESGGAERIARTLIRAFGEKNAHWAMMVVAFIIGLPVFFEVGFVLLIPIAFNVA 136 Query: 149 RRSQQPILRVAIPALAGMTTLHALLPPHPGPLIAVSALHADLGTTMLLGFVVAIPAVILA 208 +R+ PIL V +P +AG++ +H L+PPHP L+AV+A AD+G T+L +V +P ILA Sbjct: 137 KRTGTPILMVGLPMVAGLSVVHGLIPPHPAALLAVTAYQADIGKTILYALIVGLPTAILA 196 Query: 209 GPLYGMWLAPRMPIGEPEQIGALFKGQQAPELQPGFLPSLITILLPVVLMLGRTVAKIWV 268 GPL+ M ++ + + F + P F +L TILLPVVLML + A + Sbjct: 197 GPLFAMLISRHVKPDPDNPLEKQFVEADSSRELPPFGITLFTILLPVVLMLIGSWADLLA 256 Query: 269 MPETTLFEMLNFFGEPIIALTVTVLFAVVVLGWSRGVSRTDVGAILRKALPPIAGLLLTI 328 P++ ++L G ++AL + L + G +RG SR + + L PIA + L + Sbjct: 257 APKSLANDLLKLAGNSVMALLIAALVSFYTFGRARGFSREAILKFTNECLAPIATITLVV 316 Query: 329 GAGGGLKQALLTAGISDTITKVATGTHVPLILLAWLIAVALRQATGSATVATTATAGIV- 387 GAGGG Q L +G+S I VA G + +LL W++AV +R ATGSATVA T GIV Sbjct: 317 GAGGGFGQILRDSGVSKAIVAVAMGASLSPLLLGWVVAVMIRIATGSATVAMTTACGIVA 376 Query: 388 APLVASLSGTHNALMALAIGAGSVFFCHVNDAGFWMVKEYFGLDLKQTFATWSVIQTIVS 447 AS + LM LA GAGS+ HVND GFW+VKEYF L + QTF TW+V++TI+S Sbjct: 377 PIAAASGAAVRPELMVLATGAGSLILSHVNDGGFWLVKEYFNLTVPQTFQTWTVLETIIS 436 Query: 448 VV 449 +V Sbjct: 437 IV 438 >YPO3954 [GE] COG2610 H+/gluconate symporter and related permeases Ype Yersinia pestis Length = 438 Score = 294 bits (752), Expect = 4e-79, Method: Compositional matrix adjust. Identities = 173/423 (40%), Positives = 245/423 (57%), Gaps = 10/423 (2%) Query: 36 KIAPFLSILLGTFIAGTGGPGXAGLPLEKIASSFSKGAGSILGEAGIIIALGAMLGALMA 95 K+ F+S++L G G+P++K+ S G G LG +I+ GAMLG L+A Sbjct: 21 KLNGFISLILVALAVGI----MQGMPIDKVVGSIKAGVGGTLGSLALIMGFGAMLGKLLA 76 Query: 96 DSGAADKIVTTLLRYAKGAAIPWMMALVALVVGLPLFFEVGLVMMAPIIFVMARRSQQPI 155 D G A +I TTL+ I W + L VG LF+EVG V++ P++F +A ++ P+ Sbjct: 77 DCGGAQRIATTLIEKFGQKHIQWAVVLTGFTVGFALFYEVGFVLLLPLVFSIAASARIPL 136 Query: 156 LRVAIPALAGMTTLHALLPPHPGPLIAVSALHADLGTTMLLGFVVAIPAVILAGPLYGMW 215 L V +P A ++ H LPPHPGP + +AD+G T+L G ++AIP VILAGP+Y + Sbjct: 137 LYVGVPMAAALSVTHGFLPPHPGPTAIATIFNADMGKTLLYGTLLAIPTVILAGPVYARF 196 Query: 216 LAP-RMPIGEPEQIGALFKGQQAPELQPGFLPSLITILLPVVLMLGRTVAKIWVMPETTL 274 L P+ E +F ++ P F S+ T L+PV+LM R VA++ + +L Sbjct: 197 LKGIDKPVPEGLYNPKIFTDKE----MPSFGVSVSTALVPVILMALRAVAEMILPKGHSL 252 Query: 275 FEMLNFFGEPIIALTVTVLFAVVVLGWSRGVSRTDVGAILRKALPPIAGLLLTIGAGGGL 334 FFG+P+IA + VL A+ G +RG S V L ++ IA +LL IG GG Sbjct: 253 LPYAEFFGDPVIATLIAVLIAIFTFGLNRGRSVESVMETLSDSIKIIAMMLLVIGGGGAF 312 Query: 335 KQALLTAGISDTITKVATGTHVPLILLAWLIAVALRQATGSATVATTATAGIVAPLVASL 394 KQ L+ +GI I + + IL+AW IA LR A GSATVA GIVAPL+A+ Sbjct: 313 KQVLVDSGIEQYIAGMMGNSGASPILMAWSIAALLRIALGSATVAAITAGGIVAPLIAT- 371 Query: 395 SGTHNALMALAIGAGSVFFCHVNDAGFWMVKEYFGLDLKQTFATWSVIQTIVSVVGLVMT 454 +G LM +A+G+GSV F HVND GFW+ KEYF L + +T +WSV++TI+SV GL+ Sbjct: 372 TGASPELMVIAVGSGSVIFSHVNDPGFWLFKEYFNLTIMETIKSWSVLETIISVCGLIGC 431 Query: 455 LLL 457 LLL Sbjct: 432 LLL 434 >BS_gntP [GE] COG2610 H+/gluconate symporter and related permeases Bsu Bacillus subtilis Length = 448 Score = 288 bits (736), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 178/449 (39%), Positives = 259/449 (57%), Gaps = 16/449 (3%) Query: 18 LLSVLIALIAIVVLISVLKIAPFLSILLGTFIAGTGGPGXAGLPLEKIASSFSKGAGSIL 77 L+ V + ++A++ LI LK+ F+S+L+ +F G G+P +K+ SS G G L Sbjct: 3 LIIVALGILALLFLIMGLKLNTFISLLVVSF----GVALALGMPFDKVVSSIEAGIGGTL 58 Query: 78 GEAGIIIALGAMLGALMADSGAADKIVTTLLRYAKGAAIPWMMALVALVVGLPLFFEVGL 137 G +I LGAMLG L+ADSG A +I TL+ I W + + + ++G+ LFFEVGL Sbjct: 59 GHIALIFGLGAMLGKLIADSGGAQRIAMTLVNKFGEKNIQWAVVIASFIIGIALFFEVGL 118 Query: 138 VMMAPIIFVMARRSQQPILRVAIPALAGMTTLHALLPPHPGPLIAVSALHADLGTTMLLG 197 V++ PI+F ++R + IL + IP +A ++ H LPPHPGP A++G +L G Sbjct: 119 VLLIPIVFAISRELKISILFLGIPMVAALSVTHGFLPPHPGPTAIAGEYGANIGEVLLYG 178 Query: 198 FVVAIPAVILAGPLYGMWLAPRMPIGEPEQIGALFKGQQAP---ELQPGFLPSLITILLP 254 F+VA+P V++AGPL+ + +P + G Q E PGF S+ T +LP Sbjct: 179 FIVAVPTVLIAGPLFTKFAKKIVPASFAKNGNIASLGTQKTFNLEETPGFGISVFTAMLP 238 Query: 255 VVLMLGRTVAKIWVMPETTLF------EMLNFFGEPIIALTVTVLFAVVVLGWSRGVSRT 308 +++M T+ I ++ ET F + G A+ +++L AV +G R + Sbjct: 239 IIIMSVATI--IDLLQETIGFADNGVLAFIRLIGNASTAMIISLLVAVYTMGIKRNIPVK 296 Query: 309 DVGAILRKALPPIAGLLLTIGAGGGLKQALLTAGISDTITKVATGTHVPLILLAWLIAVA 368 V A+ I +LL IG GG KQ L+ G+ D + + GT + I+LAWLIA Sbjct: 297 TVMDSCSTAISQIGMMLLIIGGGGAFKQVLINGGVGDYVADLFKGTALSPIILAWLIAAI 356 Query: 369 LRQATGSATVATTATAGIVAPLVASLSGTHNALMALAIGAGSVFFCHVNDAGFWMVKEYF 428 LR + GSATVA +T G+V PL+ S + AL+ LA GAGSV HVNDAGFWM KEYF Sbjct: 357 LRISLGSATVAALSTTGLVIPLLGH-SDVNLALVVLATGAGSVIASHVNDAGFWMFKEYF 415 Query: 429 GLDLKQTFATWSVIQTIVSVVGLVMTLLL 457 GL +K+TFATW++++TI+SV GL LLL Sbjct: 416 GLSMKETFATWTLLETIISVAGLGFILLL 444