BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0189.p (388 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0989 [KE] COG1167 Transcriptional regulators containing a DNA... 285 2e-76 PA5283 [KE] COG1167 Transcriptional regulators containing a DNA-... 269 9e-72 RSp1057 [KE] COG1167 Transcriptional regulators containing a DNA... 256 5e-68 BMEI0169 [KE] COG1167 Transcriptional regulators containing a DN... 255 1e-67 AGc398 [KE] COG1167 Transcriptional regulators containing a DNA-... 246 4e-65 >RSc0989 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Rso Ralstonia solanacearum Length = 490 Score = 285 bits (728), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 148/371 (39%), Positives = 224/371 (60%), Gaps = 8/371 (2%) Query: 16 RAMDVVWLMREQLKSDPEHLRLGDGFPPVDWLNEVRLDKFHQKVVRTGLGALFGYGSRFG 75 R +DV WL+R S G GF P WL+ + + + R +G+ G Sbjct: 117 RKIDVAWLLRNMFHSAEPRKAPGIGFLPNGWLDGELIANALRALGRQNGNQFLAWGTPQG 176 Query: 76 YQPLRQHLVHRLANHGIDASASQIVLTHGANQALDIVIRNFVKPGDRVLVDEPGYYMLFG 135 + PLRQ L RLA I A QIV+T G Q+LD++ R +V+PGD VLV +P ++++FG Sbjct: 177 FLPLRQQLQTRLAELEIGARPDQIVMTSGITQSLDLIARQYVQPGDTVLVGDPAWFLMFG 236 Query: 136 KLKLGGARIVGIPRLADGPDLEALERELKIGKPCLFFTQTLAHNPTGSDTSPHKAHKILQ 195 + GA+++G+P +GPDL ALE +++ +P L ++ HNPTG+ S KA ++L+ Sbjct: 237 RFAAQGAQVIGVPYTTEGPDLVALEGLVQVRRPKLLVINSVLHNPTGTSLSAAKAFQLLR 296 Query: 196 LADRYNAIVVENDTFADFKPNAAP--RISTLDQLRRTIYVGSFSKSVSAALRVGFLACHR 253 LA++Y ++VE+D + D P P R+++LDQLRR IY+GSFSK+++A LRVGF+ACH Sbjct: 297 LAEQYGFLIVEDDIYGDLAPPGHPATRLASLDQLRRVIYLGSFSKTLAANLRVGFIACHP 356 Query: 254 DLASDLADIKMLVHVSSSEYCERTLDVILSEGHYSRHAARLRDRLTQATESSRRLLENMG 313 +LA +L D K+L +++ E ER L +L+EG Y +H R+R RL +A + +R LE +G Sbjct: 357 ELAKNLTDGKLLAGLATPEINERVLYKVLTEGQYRKHVERVRARLDRARDGVQRSLERLG 416 Query: 314 AELFCSPAQSMYLWAAMPGYPDSKALAQALMRQNIVTAPGSIFHIDTEAPSRWSRYNVGL 373 +LF M++WA D+ A+A+A + V APGS+F ++ PS W R+N+ Sbjct: 417 LKLFAQQGAGMFIWADTG--RDTNAIARAGHEEGYVFAPGSLFS-PSQMPSTWMRFNIAT 473 Query: 374 LGDP---RFAA 381 DP RF A Sbjct: 474 STDPEMLRFLA 484 >PA5283 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Pae Pseudomonas aeruginosa Length = 458 Score = 269 bits (687), Expect = 9e-72, Method: Compositional matrix adjust. Identities = 142/360 (39%), Positives = 209/360 (58%), Gaps = 2/360 (0%) Query: 27 QLKSDPEHLRLGDGFPPVDWLNEVRLDKFHQKVVRTGLGALFGYGSRFGYQPLRQHLVHR 86 Q L+LG G+ P W L ++V R+ L LF Y + G LRQH+ R Sbjct: 100 QFSGSSTKLKLGCGWIPDSWREVEELSYAIRQVARSELAGLFDYSTPLGLPALRQHIQKR 159 Query: 87 LANHGIDASASQIVLTHGANQALDIVIRNFVKPGDRVLVDEPGYYMLFGKLKLGGARIVG 146 L I QI+ T GA+ ALD+++R +KPGD V+V+ PGYY LF LK G +++G Sbjct: 160 LRLIDIHVDPEQILTTTGASHALDLLVRTLLKPGDVVVVENPGYYNLFNLLKFHGVKMLG 219 Query: 147 IPRLADGPDLEALERELKIGKPCLFFTQTLAHNPTGSDTSPHKAHKILQLADRYNAIVVE 206 +PR GPD ALE L+ KP FT ++ HNPTG+ SP AH++LQLA++++ +VE Sbjct: 220 VPRTRHGPDTAALETILRAHKPKFLFTNSMYHNPTGTSLSPSVAHRVLQLAEQHDFHIVE 279 Query: 207 NDTFADFKPNAAPRISTLDQLRRTIYVGSFSKSVSAALRVGFLACHRDLASDLADIKMLV 266 +D +ADF+ + R++TLD LRR IY+ SFSK++S +LRVG+L +L LAD+KM Sbjct: 280 DDIYADFQNGPSTRLATLDSLRRVIYLASFSKTLSCSLRVGYLIAGPELIRRLADVKMYT 339 Query: 267 HVSSSEYCERTLDVILSEGHYSRHAARLRDRLTQATESSRRLLENMGAELFCSPAQSMYL 326 + S + E + +L+ G Y + RLR RLT+ ++ R+L + G E+F P M++ Sbjct: 340 SIGSQRFAECVVSTMLANGSYRKLVQRLRQRLTRQMAATLRVLGDNGWEVFAEPVGGMFV 399 Query: 327 WAAMPGYPDSKALAQALMRQNIVTAPGSIFHIDTEAPSRWSRYNVGLLGDPRFAAAMQGL 386 WA + YP ++ A A R +++ +PGS F + E S W R N+ DPR A + Sbjct: 400 WARIGDYPFAELQAVA-TRLDVLLSPGSGFSPEGEE-SDWLRINIAYASDPRALAFFEAF 457 >RSp1057 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Rso Ralstonia solanacearum Length = 471 Score = 256 bits (655), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 141/383 (36%), Positives = 214/383 (55%), Gaps = 11/383 (2%) Query: 5 TAASAPMKPXS-------RAMDVVWLMREQLKSDPEHLRLGDGFPPVDWLNEVRLDKFHQ 57 AA AP++P A++ WL+ + ++ G G+ P DWL+E + + + Sbjct: 81 VAARAPVQPVPVAPRWEPPALNAAWLLSDVFADRSIAIKPGCGWLPNDWLDERGVQEAMR 140 Query: 58 KVVRTGLGALFGYGSRFGYQPLRQHLVHRLANHGIDASASQIVLTHGANQALDIVIRNFV 117 V R + GYG +GY PL +++ LA G+ +Q++LT GA QALD+++R Sbjct: 141 MVSRVSALRVAGYGHPWGYAPLGEYVAQSLALRGLPVERAQVLLTSGATQALDLIVRTLF 200 Query: 118 KPGDRVLVDEPGYYMLFGKLKLGGARIVGIPRLADGPDLEALE---RELKIGKPCLFFTQ 174 K GD V V++P Y + LKL G R+VG+PR +G D ALE R+ + +P F Sbjct: 201 KAGDVVAVEDPVYCNVLQVLKLAGLRVVGVPRTPEGLDTAALETVLRQDEASRPRALFVS 260 Query: 175 TLAHNPTGSDTSPHKAHKILQLADRYNAIVVENDTFADFKPNAAPRISTLDQLRRTIYVG 234 T+ NPTGS + A+++LQLA+++ +VE+D + AAP ++ LD LRRT+YV Sbjct: 261 TVLQNPTGSSMTAQNAYRVLQLAEQHGLWIVEDDLHRELADPAAPMLAALDGLRRTLYVS 320 Query: 235 SFSKSVSAALRVGFLACHRDLASDLADIKMLVHVSSSEYCERTLDVILSEGHYSRHAARL 294 FSK++S +LR G++ + +LA KM V ++SSE ER + ++ Y+ H ARL Sbjct: 321 GFSKTISPSLRAGYVVADAAITRELARTKMAVALTSSEITERIVHAFVTRPAYAEHVARL 380 Query: 295 RDRLTQATESSRRLLENMGAELFCSPAQSMYLWAAMPGYPDSKALAQALMRQNIVTAPGS 354 RL A + GA +F +P + ++LWA +PG+ D+ ALA +R NI APG Sbjct: 381 NARLGAAHAGVEATMREHGAVVFDTPGRGLFLWARLPGHADASALADRAIRGNIWLAPGQ 440 Query: 355 IFHIDTEAPSRWSRYNVGLLGDP 377 F D +A S W R+NV GDP Sbjct: 441 YFRPD-DAASPWLRFNVAYSGDP 462 >BMEI0169 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Bme Brucella melitensis Length = 484 Score = 255 bits (651), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 135/382 (35%), Positives = 210/382 (54%), Gaps = 3/382 (0%) Query: 3 ISTAASAPMKPXSRAMDVVWLMREQLKSDPEHLRLGDGFPPVDWLNEVRLDKFHQKVVRT 62 S AA+AP K R +D W+MR+ L+++ L+ G G+ P WL + L + + + R Sbjct: 98 FSLAATAPHK--DRQIDPFWVMRQSLEAESRTLKPGCGWLPDGWLPQEALRRALRTIARD 155 Query: 63 GLGALFGYGSRFGYQPLRQHLVHRLANHGIDASASQIVLTHGANQALDIVIRNFVKPGDR 122 L YG G++PLRQHL HRL GID + +I+LT QA+D++ R ++PGD Sbjct: 156 DQSNLTTYGEPLGFRPLRQHLAHRLGEQGIDIAGGEILLTDSGTQAIDLICRYLLQPGDT 215 Query: 123 VLVDEPGYYMLFGKLKLGGARIVGIPRLADGPDLEALERELKIGKPCLFFTQTLAHNPTG 182 VLVD+P Y+ L ++VG+P GPDL+A P L+ + HNPTG Sbjct: 216 VLVDDPCYFNFQAVLLTHRVKLVGVPYTHSGPDLDAFANAATEHAPKLYISNAGLHNPTG 275 Query: 183 SDTSPHKAHKILQLADRYNAIVVENDTFADFKPNAAPRISTLDQLRRTIYVGSFSKSVSA 242 +P AH++L+LA+ + +VE++ F DF P+ P ++ LD R +++GSFSK++SA Sbjct: 276 GIMTPATAHRLLKLAEAHGITLVEDNIFGDFHPSPTPLLAELDGFERVLHIGSFSKTLSA 335 Query: 243 ALRVGFLACHRDLASDLADIKMLVHVSSSEYCERTLDVILSEGHYSRHAARLRDRLTQAT 302 A RVG++A RD L D+K+ + + + +L +G Y RH LR RL A Sbjct: 336 AARVGYIAGRRDWIEGLTDLKLATSFGCNALSPQIVHALLIDGTYRRHIESLRTRLADAM 395 Query: 303 ESSRRLLENMGAELFCSPAQSMYLWAAMPGYPDSKALAQALMRQNIVTAPGSIFHIDTEA 362 + L+ G +L+ P M+LWA +P DS +A+ + + +V APG++F A Sbjct: 396 TLTANRLKATGLDLWTKPQGGMFLWARLPDGMDSGPVARHALEKGVVLAPGNVFSPSCTA 455 Query: 363 PSRWSRYNVGLLGDPRFAAAMQ 384 + + R+NV DP A ++ Sbjct: 456 -AGFLRFNVAQSADPYIYAVLR 476 >AGc398 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 449 Score = 246 bits (629), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 130/363 (35%), Positives = 202/363 (55%), Gaps = 1/363 (0%) Query: 16 RAMDVVWLMREQLKSDPEHLRLGDGFPPVDWLNEVRLDKFHQKVVRTGLGALFGYGSRFG 75 RA+D +W+ R+ L + G G+ P W+ + L + + + R L YGS G Sbjct: 78 RAVDPLWVSRQALDDGSALAKPGCGWLPASWMPQEALRRAMRGLARADDALLTDYGSPMG 137 Query: 76 YQPLRQHLVHRLANHGIDASASQIVLTHGANQALDIVIRNFVKPGDRVLVDEPGYYMLFG 135 PLRQ L RLA HG+ A ASQI+LT QA+D++ R ++PGD V+VD+P Y+ Sbjct: 138 LLPLRQLLSRRLAEHGVQAGASQIMLTDSGTQAIDLLCRFLLQPGDTVVVDDPCYFNFHA 197 Query: 136 KLKLGGARIVGIPRLADGPDLEALERELKIGKPCLFFTQTLAHNPTGSDTSPHKAHKILQ 195 L+ +IVG+P GPDL E+ LK +P L+ T + HNPTG+ S AH++L Sbjct: 198 LLRAHRVKIVGVPYTPAGPDLPLFEQALKEHQPRLYITNSAIHNPTGARLSAVSAHRLLM 257 Query: 196 LADRYNAIVVENDTFADFKPNAAPRISTLDQLRRTIYVGSFSKSVSAALRVGFLACHRDL 255 LA++ ++E+D FADF+ AAPR++ D L R + +GSFSK++SA++R GF+A R Sbjct: 258 LAEQPGLTIIEDDIFADFETQAAPRLAAFDGLNRVVQIGSFSKTLSASVRCGFIAAPRAW 317 Query: 256 ASDLADIKMLVHVSSSEYCERTLDVILSEGHYSRHAARLRDRLTQATESSRRLLENMGAE 315 L D+K+ + + + +L++G Y +H LR RL A + L ++G Sbjct: 318 VEALTDLKIATAFGGTHFSAALVLSLLTDGSYRKHVEALRQRLAAAVPEAATRLRSIGCM 377 Query: 316 LFCSPAQSMYLWAAMPGYPDSKALAQALMRQNIVTAPGSIFHIDTEAPSRWSRYNVGLLG 375 + P M+LW +P D+ +AQ + + +V APG++F A S + R+NV + Sbjct: 378 PWIEPQAGMFLWCRLPEGTDAADVAQRALARQVVLAPGNVFSSSQNA-SGFMRFNVSQMV 436 Query: 376 DPR 378 P+ Sbjct: 437 GPQ 439