BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0184.p (763 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1927 [E] COG0620 Methionine synthase II (cobalamin-independent... 910 0.0 YPO3788 [E] COG0620 Methionine synthase II (cobalamin-independen... 892 0.0 metE [E] COG0620 Methionine synthase II (cobalamin-independent) ... 887 0.0 ZmetE [E] COG0620 Methionine synthase II (cobalamin-independent)... 887 0.0 ECs4759 [E] COG0620 Methionine synthase II (cobalamin-independen... 887 0.0 >PA1927 [E] COG0620 Methionine synthase II (cobalamin-independent) Pae Pseudomonas aeruginosa Length = 766 Score = 910 bits (2353), Expect = 0.0, Method: Compositional matrix adjust. Identities = 467/767 (60%), Positives = 566/767 (73%), Gaps = 14/767 (1%) Query: 1 MTTIHNLGFPRIGAKRELKFALESYWKGESSRDELKNLGAQLRQRHWDNQ--AGLDFVPV 58 M H LGFPRIG RELK A E++WKGE L+ +G QLR HW Q AG+ +PV Sbjct: 1 MALAHTLGFPRIGRDRELKKAQEAFWKGELDEAGLRAVGRQLRAAHWQVQKDAGIQLLPV 60 Query: 59 GDFAFYDQVLDMSFTLGNLPERVRDFHGD---TLDNYFRVARGRSAQGAEDHGACCAGVA 115 GDFA+YDQVL S T G +PER R HG+ TL F +ARG S +CC G Sbjct: 61 GDFAWYDQVLTHSLTFGVIPERFRA-HGEAGPTLHTLFGMARGVS------DDSCCGGAH 113 Query: 116 AGEMTKWFDTNYHYIVPEFTASTEFKLDTSRLLTQLAEAKAQGIKAKPVIVGPVTYLALG 175 A EMTKWFDTNYHY+VPEF+A +F+L +L ++ EA+A G + KPV++GP+TYL LG Sbjct: 114 AQEMTKWFDTNYHYLVPEFSADQQFQLSWEQLFEEVDEARALGHQVKPVLIGPLTYLWLG 173 Query: 176 KAKD-DSDKLALLPRLLPVYVQLLDALAAQGIEWVQIDEPVLVTELDAAWKNAFNTAYAA 234 KAK + D+L LL RLLP+Y Q+ LA QG+EWVQIDEP+LV +L AWKNAF AY Sbjct: 174 KAKGAEFDRLDLLDRLLPLYGQIFRRLAGQGVEWVQIDEPILVLDLPQAWKNAFERAYNL 233 Query: 235 LKNSGVKLLLATYFGELLENQKLAASLPVAGLHIDAINGRNDVLPLIELLAADKVLSLGV 294 L++ +K L+ATYFG L +N LAA+LPV GLHID + +++ L A KV+SLG+ Sbjct: 234 LQSEPLKKLVATYFGGLEDNLGLAANLPVDGLHIDLVRAPEQYPSILDRLPAYKVVSLGL 293 Query: 295 INGRNIWKTDLSAVLDWLEPLANRLGERLWVAPSCSLLHVPVDLNSEQKLDGEIKSWLAY 354 +NGRN+W+ DL L+ + RLGERLWVAPSCSLLH PVDL E LD E+KSWLA+ Sbjct: 294 VNGRNVWRCDLEKALEVVRHARERLGERLWVAPSCSLLHSPVDLEREDGLDAELKSWLAF 353 Query: 355 AQQKLDELRLLGKALRQGRDA-VKAELAANQAALAARRASPRVNDPAVQAAVAGIDSQLG 413 A QK E+ +L +A + A V A L ++A A+R +SPR++ PAVQA +A I + Sbjct: 354 AVQKCREVAVLARAATEPEAAEVLAALEESRAVQASRASSPRIHKPAVQARLAAIKASDA 413 Query: 414 RRANVYQQRAVRQAALLKLPAYPTTTIGSFPQTPEIRHARSEFKAGRLDNAGYKTAMQAE 473 +R + + +R RQ A L LPA+PTTTIGSFPQT IR AR FK G+L A Y AM +E Sbjct: 414 QRRSPFAERIARQRAGLDLPAFPTTTIGSFPQTSSIRLARQSFKQGKLSEAEYIEAMHSE 473 Query: 474 IQRSVREQETLGLDVLVHGEAERNDMVEYFGEQLQGYAFSQFGWVQSYGSRCVKPPILFG 533 I+ +V+ QE LGLDVLVHGEAERNDMVEYF EQL GY F++FGWVQSYGSRCVKP +++G Sbjct: 474 IRHAVQIQEQLGLDVLVHGEAERNDMVEYFAEQLDGYVFTRFGWVQSYGSRCVKPAVIYG 533 Query: 534 DISRPQAMTVEWITYAQSLTAKPMKGMLTGPVTILNWSFVRDDQPRSVSCKQLALAIRDE 593 D+SRP+AMTVEWI YAQSLT K MKGMLTGPVT+L WSF R+D R V +QLALAIRDE Sbjct: 534 DLSRPRAMTVEWIRYAQSLTDKVMKGMLTGPVTMLMWSFPREDVSREVQARQLALAIRDE 593 Query: 594 VLDLEKAGVRIIQIDEAALREGLPLRKSQWKEYLDWAVESFRITANGVGDETQIHTHMCY 653 V+DLE AG+RI+QIDEAA REGLPLR++ W YL+WA E+FR+ A+GV DETQIHTHMCY Sbjct: 594 VVDLEAAGIRIVQIDEAAFREGLPLRRNAWPHYLEWATEAFRLCASGVRDETQIHTHMCY 653 Query: 654 SEFNDIIASIADMDADVITIETSRSDMELLDAFDNFNYPNEIGPGVYDIHSPNIPTQEHI 713 SEFND+I SIA MDADVITIETSRSDMELL+AF+ F+YPNEIGPGVYDIHSP +P++E I Sbjct: 654 SEFNDVIESIAAMDADVITIETSRSDMELLEAFEQFDYPNEIGPGVYDIHSPRVPSREEI 713 Query: 714 VQLMKKAAERIPVERLWVNPDCGLKTRQWAEVLPALGNMVAAARTLR 760 V L++KAA RIP ERLWVNPDCGLKTR W E AL NMVAAAR LR Sbjct: 714 VALLRKAARRIPAERLWVNPDCGLKTRAWPETEAALVNMVAAARELR 760 >YPO3788 [E] COG0620 Methionine synthase II (cobalamin-independent) Ype Yersinia pestis Length = 758 Score = 892 bits (2306), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/765 (59%), Positives = 553/765 (72%), Gaps = 16/765 (2%) Query: 1 MTTI-HNLGFPRIGAKRELKFALESYWKGESSRDELKNLGAQLRQRHWDNQ--AGLDFVP 57 MT + H LGFPR+G KRELK A ESYW G S+++EL N+G +LR RHW Q AG+D VP Sbjct: 1 MTILNHTLGFPRVGLKRELKKAQESYWAGNSTQEELLNVGRELRARHWQQQQQAGVDLVP 60 Query: 58 VGDFAFYDQVLDMSFTLGNLPERVRDFHGDT-LDNYFRVARGRSAQGAEDHGACCAGVAA 116 VGDFA+YD VL S LGN+PER ++ G +D FR+ RGR+ G AA Sbjct: 61 VGDFAWYDHVLTTSLLLGNVPERHQNADGSIDIDTLFRIGRGRAPTGKP--------AAA 112 Query: 117 GEMTKWFDTNYHYIVPEFTASTEFKLDTSRLLTQLAEAKAQGIKAKPVIVGPVTYLALGK 176 EMTKWF+TNYHY+VPEF +FKL ++LL ++ EA A G K KPV++GP+TYL LGK Sbjct: 113 AEMTKWFNTNYHYMVPEFQQGQQFKLGWTQLLDEVDEALALGHKIKPVLLGPITYLWLGK 172 Query: 177 AKDDS-DKLALLPRLLPVYVQLLDALAAQGIEWVQIDEPVLVTELDAAWKNAFNTAYAAL 235 K + D+L+LL +LPVY Q+L LA +GIEWVQIDEP LV EL W +A+ AY AL Sbjct: 173 VKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQEWLDAYQPAYQAL 232 Query: 236 KNSGVKLLLATYFGELLENQKLAASLPVAGLHIDAINGRNDVLPLIELLAADKVLSLGVI 295 + VKLLL TYF + N +LPV GLH+D + G +D+ L + L + +LSLGVI Sbjct: 233 QGQ-VKLLLTTYFDSIGHNIDTIRALPVQGLHVDVVTGHDDLAVLNKNLPKEWLLSLGVI 291 Query: 296 NGRNIWKTDLSAVLDWLEPLANRLGERLWVAPSCSLLHVPVDLNSEQKLDGEIKSWLAYA 355 NGRN+W+ DLS+ + L+PL N LW+ SCSLLH P+DLN E +LD E+KSW A+A Sbjct: 292 NGRNVWRADLSSWFERLQPLVN--SRPLWLGSSCSLLHSPIDLNEETRLDAEVKSWFAFA 349 Query: 356 QQKLDELRLLGKALRQGRDAVKAELAANQAALAARRASPRVNDPAVQAAVAGIDSQLGRR 415 QK EL LL +AL DA AELAA A + ARR+S RV++ V+ +A I SQ R Sbjct: 350 LQKCAELALLTQALNAPNDAKLAELAAYSAPIRARRSSSRVHNAQVEQRLAAITSQDIER 409 Query: 416 ANVYQQRAVRQAALLKLPAYPTTTIGSFPQTPEIRHARSEFKAGRLDNAGYKTAMQAEIQ 475 Y+ RA Q LPA+PTTTIGSFPQT EIR R +FK GRLD Y+T + I+ Sbjct: 410 QLPYEARAETQRKRFNLPAWPTTTIGSFPQTTEIRGLRLDFKQGRLDGKNYRTGISEHIK 469 Query: 476 RSVREQETLGLDVLVHGEAERNDMVEYFGEQLQGYAFSQFGWVQSYGSRCVKPPILFGDI 535 ++ EQE LGLDVLVHGEAERNDMVEYFGE L G+ F+Q GWVQSYGSRCVKPP++ GDI Sbjct: 470 HAIAEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVIIGDI 529 Query: 536 SRPQAMTVEWITYAQSLTAKPMKGMLTGPVTILNWSFVRDDQPRSVSCKQLALAIRDEVL 595 SRP+A+TVEW YAQSLT KP+KGMLTGPVTIL WSF R+D R KQ+ALA+RDEV Sbjct: 530 SRPEAITVEWAKYAQSLTEKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVE 589 Query: 596 DLEKAGVRIIQIDEAALREGLPLRKSQWKEYLDWAVESFRITANGVGDETQIHTHMCYSE 655 DLEKAG+ IIQIDE ALREGLPLR++ W+ YL WAV++F++ A ++TQIHTHMCY E Sbjct: 590 DLEKAGIGIIQIDEPALREGLPLRRADWQAYLQWAVDAFKLNAAVAQNDTQIHTHMCYCE 649 Query: 656 FNDIIASIADMDADVITIETSRSDMELLDAFDNFNYPNEIGPGVYDIHSPNIPTQEHIVQ 715 FNDI+ SIA +DADVITIETSRSDMELL++F++F YPNEIGPGVYDIHSPN+P+ E I Sbjct: 650 FNDIMDSIAALDADVITIETSRSDMELLESFEDFAYPNEIGPGVYDIHSPNVPSVEWIEA 709 Query: 716 LMKKAAERIPVERLWVNPDCGLKTRQWAEVLPALGNMVAAARTLR 760 L++KAA+RIP ERLWVNPDCGLKTR W E AL NMV AA+ LR Sbjct: 710 LLRKAAQRIPAERLWVNPDCGLKTRGWPETRQALANMVLAAQRLR 754 >metE [E] COG0620 Methionine synthase II (cobalamin-independent) Eco Escherichia coli K12 Length = 753 Score = 887 bits (2292), Expect = 0.0, Method: Compositional matrix adjust. Identities = 456/766 (59%), Positives = 555/766 (72%), Gaps = 21/766 (2%) Query: 1 MTTI-HNLGFPRIGAKRELKFALESYWKGESSRDELKNLGAQLRQRHWD--NQAGLDFVP 57 MT + H LGFPR+G +RELK A ESYW G S+R+EL +G +LR RHWD QAG+D +P Sbjct: 1 MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLP 60 Query: 58 VGDFAFYDQVLDMSFTLGNLPERVRDFHGDT-LDNYFRVARGRSAQGAEDHGACCAGVAA 116 VGDFA+YD VL S LGN+P R ++ G +D FR+ RGR+ G AA Sbjct: 61 VGDFAWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRGRAPTGEP--------AAA 112 Query: 117 GEMTKWFDTNYHYIVPEFTASTEFKLDTSRLLTQLAEAKAQGIKAKPVIVGPVTYLALGK 176 EMTKWF+TNYHY+VPEF +FKL ++LL ++ EA A G K KPV++GPVT+L LGK Sbjct: 113 AEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPVLLGPVTWLWLGK 172 Query: 177 AKDDS-DKLALLPRLLPVYVQLLDALAAQGIEWVQIDEPVLVTELDAAWKNAFNTAYAAL 235 K + D+L+LL +LPVY Q+L LA +GIEWVQIDEP LV EL AW +A+ AY AL Sbjct: 173 VKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDAL 232 Query: 236 KNSGVKLLLATYFGELLENQKLAASLPVAGLHIDAINGRNDVLPLIELLAADKVLSLGVI 295 + VKLLL TYF + N +LPV GLH+D ++G++DV L + L +D +LS G+I Sbjct: 233 QGQ-VKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAELHKRLPSDWLLSAGLI 291 Query: 296 NGRNIWKTDLSAVLDWLEPLANRLGER-LWVAPSCSLLHVPVDLNSEQKLDGEIKSWLAY 354 NGRN+W+ DL+ ++ + +G+R LWVA SCSLLH P+DL+ E +LD E+KSW A+ Sbjct: 292 NGRNVWRADLTEKYAQIKDI---VGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAF 348 Query: 355 AQQKLDELRLLGKALRQGRDAVKAELAANQAALAARRASPRVNDPAVQAAVAGIDSQLGR 414 A QK EL LL AL G A AE +A + ARR S RV++PAV+ +A I +Q + Sbjct: 349 ALQKCHELALLRDALNSGDTAALAEWSA---PIQARRHSTRVHNPAVEKRLAAITAQDSQ 405 Query: 415 RANVYQQRAVRQAALLKLPAYPTTTIGSFPQTPEIRHARSEFKAGRLDNAGYKTAMQAEI 474 RANVY+ RA Q A KLPA+PTTTIGSFPQT EIR R +FK G LD Y+T + I Sbjct: 406 RANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHI 465 Query: 475 QRSVREQETLGLDVLVHGEAERNDMVEYFGEQLQGYAFSQFGWVQSYGSRCVKPPILFGD 534 ++++ EQE LGLDVLVHGEAERNDMVEYFGE L G+ F+Q GWVQSYGSRCVKPPI+ GD Sbjct: 466 KQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGD 525 Query: 535 ISRPQAMTVEWITYAQSLTAKPMKGMLTGPVTILNWSFVRDDQPRSVSCKQLALAIRDEV 594 ISRP +TVEW YAQSLT KP+KGMLTGPVTIL WSF R+D R KQ+ALA+RDEV Sbjct: 526 ISRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEV 585 Query: 595 LDLEKAGVRIIQIDEAALREGLPLRKSQWKEYLDWAVESFRITANGVGDETQIHTHMCYS 654 DLE AG+ IIQIDE ALREGLPLR+S W YL W VE+FRI A D+TQIHTHMCY Sbjct: 586 ADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYC 645 Query: 655 EFNDIIASIADMDADVITIETSRSDMELLDAFDNFNYPNEIGPGVYDIHSPNIPTQEHIV 714 EFNDI+ SIA +DADVITIETSRSDMELL++F+ F+YPNEIGPGVYDIHSPN+P+ E I Sbjct: 646 EFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIE 705 Query: 715 QLMKKAAERIPVERLWVNPDCGLKTRQWAEVLPALGNMVAAARTLR 760 L+KKAA+RIP ERLWVNPDCGLKTR W E AL NMV AA+ LR Sbjct: 706 ALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLR 751 >ZmetE [E] COG0620 Methionine synthase II (cobalamin-independent) EcZ Escherichia coli O157:H7 EDL933 Length = 753 Score = 887 bits (2291), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/766 (59%), Positives = 556/766 (72%), Gaps = 21/766 (2%) Query: 1 MTTI-HNLGFPRIGAKRELKFALESYWKGESSRDELKNLGAQLRQRHWD--NQAGLDFVP 57 MT + H LGFPR+G +RELK A ESYW G S+R+EL +G +LR RHWD QAG+D +P Sbjct: 1 MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLP 60 Query: 58 VGDFAFYDQVLDMSFTLGNLPERVRDFHGDT-LDNYFRVARGRSAQGAEDHGACCAGVAA 116 VGDFA+YD VL S LGN+P R ++ G +D FR+ RGR+ G AA Sbjct: 61 VGDFAWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRGRAPTGEP--------AAA 112 Query: 117 GEMTKWFDTNYHYIVPEFTASTEFKLDTSRLLTQLAEAKAQGIKAKPVIVGPVTYLALGK 176 EMTKWF+TNYHY+VPEF +FKL ++LL ++ EA A G K KPV++GP+T+L LGK Sbjct: 113 AEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPVLLGPITWLWLGK 172 Query: 177 AKDDS-DKLALLPRLLPVYVQLLDALAAQGIEWVQIDEPVLVTELDAAWKNAFNTAYAAL 235 K + D+L+LL +LPVY Q+L LA +GIEWVQIDEP LV EL AW +A+ AY AL Sbjct: 173 VKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDAL 232 Query: 236 KNSGVKLLLATYFGELLENQKLAASLPVAGLHIDAINGRNDVLPLIELLAADKVLSLGVI 295 + VKLLL TYF + N +LPV GLH+D ++G++DV+ L + L +D +LS G+I Sbjct: 233 QGQ-VKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVVELHKRLPSDWLLSAGLI 291 Query: 296 NGRNIWKTDLSAVLDWLEPLANRLGER-LWVAPSCSLLHVPVDLNSEQKLDGEIKSWLAY 354 NGRN+W+ DL+ ++ + +G+R LWVA SCSLLH P+DL+ E +LD E+KSW A+ Sbjct: 292 NGRNVWRADLTEKYVQIKDI---VGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAF 348 Query: 355 AQQKLDELRLLGKALRQGRDAVKAELAANQAALAARRASPRVNDPAVQAAVAGIDSQLGR 414 A QK EL LL AL G A AE +A + ARR S RV++PAV+ +A I +Q + Sbjct: 349 ALQKCHELALLCDALNSGDTAALAEWSA---PIQARRHSTRVHNPAVEKRLAAITAQDSQ 405 Query: 415 RANVYQQRAVRQAALLKLPAYPTTTIGSFPQTPEIRHARSEFKAGRLDNAGYKTAMQAEI 474 RANVY+ RA Q A KLPA+PTTTIGSFPQT EIR R +FK G LD Y+T + I Sbjct: 406 RANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHI 465 Query: 475 QRSVREQETLGLDVLVHGEAERNDMVEYFGEQLQGYAFSQFGWVQSYGSRCVKPPILFGD 534 ++++ EQE LGLDVLVHGEAERNDMVEYFGE L G+ F+Q GWVQSYGSRCVKPPI+ GD Sbjct: 466 RQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGD 525 Query: 535 ISRPQAMTVEWITYAQSLTAKPMKGMLTGPVTILNWSFVRDDQPRSVSCKQLALAIRDEV 594 +SRP +TVEW YAQS+T KP+KGMLTGPVTIL WSF R+D R KQ+ALA+RDEV Sbjct: 526 VSRPAPITVEWAKYAQSMTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEV 585 Query: 595 LDLEKAGVRIIQIDEAALREGLPLRKSQWKEYLDWAVESFRITANGVGDETQIHTHMCYS 654 DLE AG+ IIQIDE ALREGLPLR+S W YL W VE+FRI A D+TQIHTHMCY Sbjct: 586 ADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYC 645 Query: 655 EFNDIIASIADMDADVITIETSRSDMELLDAFDNFNYPNEIGPGVYDIHSPNIPTQEHIV 714 EFNDI+ SIA +DADVITIETSRSDMELL++F+ F+YPNEIGPGVYDIHSPN+P+ E I Sbjct: 646 EFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIE 705 Query: 715 QLMKKAAERIPVERLWVNPDCGLKTRQWAEVLPALGNMVAAARTLR 760 L+KKAA+RIP ERLWVNPDCGLKTR W E AL NMV AA+ LR Sbjct: 706 ALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLR 751 >ECs4759 [E] COG0620 Methionine synthase II (cobalamin-independent) Ecs Escherichia coli O157:H7 Length = 753 Score = 887 bits (2291), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/766 (59%), Positives = 556/766 (72%), Gaps = 21/766 (2%) Query: 1 MTTI-HNLGFPRIGAKRELKFALESYWKGESSRDELKNLGAQLRQRHWD--NQAGLDFVP 57 MT + H LGFPR+G +RELK A ESYW G S+R+EL +G +LR RHWD QAG+D +P Sbjct: 1 MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLP 60 Query: 58 VGDFAFYDQVLDMSFTLGNLPERVRDFHGDT-LDNYFRVARGRSAQGAEDHGACCAGVAA 116 VGDFA+YD VL S LGN+P R ++ G +D FR+ RGR+ G AA Sbjct: 61 VGDFAWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRGRAPTGEP--------AAA 112 Query: 117 GEMTKWFDTNYHYIVPEFTASTEFKLDTSRLLTQLAEAKAQGIKAKPVIVGPVTYLALGK 176 EMTKWF+TNYHY+VPEF +FKL ++LL ++ EA A G K KPV++GP+T+L LGK Sbjct: 113 AEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPVLLGPITWLWLGK 172 Query: 177 AKDDS-DKLALLPRLLPVYVQLLDALAAQGIEWVQIDEPVLVTELDAAWKNAFNTAYAAL 235 K + D+L+LL +LPVY Q+L LA +GIEWVQIDEP LV EL AW +A+ AY AL Sbjct: 173 VKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDAL 232 Query: 236 KNSGVKLLLATYFGELLENQKLAASLPVAGLHIDAINGRNDVLPLIELLAADKVLSLGVI 295 + VKLLL TYF + N +LPV GLH+D ++G++DV+ L + L +D +LS G+I Sbjct: 233 QGQ-VKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVVELHKRLPSDWLLSAGLI 291 Query: 296 NGRNIWKTDLSAVLDWLEPLANRLGER-LWVAPSCSLLHVPVDLNSEQKLDGEIKSWLAY 354 NGRN+W+ DL+ ++ + +G+R LWVA SCSLLH P+DL+ E +LD E+KSW A+ Sbjct: 292 NGRNVWRADLTEKYVQIKDI---VGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAF 348 Query: 355 AQQKLDELRLLGKALRQGRDAVKAELAANQAALAARRASPRVNDPAVQAAVAGIDSQLGR 414 A QK EL LL AL G A AE +A + ARR S RV++PAV+ +A I +Q + Sbjct: 349 ALQKCHELALLCDALNSGDTAALAEWSA---PIQARRHSTRVHNPAVEKRLAAITAQDSQ 405 Query: 415 RANVYQQRAVRQAALLKLPAYPTTTIGSFPQTPEIRHARSEFKAGRLDNAGYKTAMQAEI 474 RANVY+ RA Q A KLPA+PTTTIGSFPQT EIR R +FK G LD Y+T + I Sbjct: 406 RANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHI 465 Query: 475 QRSVREQETLGLDVLVHGEAERNDMVEYFGEQLQGYAFSQFGWVQSYGSRCVKPPILFGD 534 ++++ EQE LGLDVLVHGEAERNDMVEYFGE L G+ F+Q GWVQSYGSRCVKPPI+ GD Sbjct: 466 RQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGD 525 Query: 535 ISRPQAMTVEWITYAQSLTAKPMKGMLTGPVTILNWSFVRDDQPRSVSCKQLALAIRDEV 594 +SRP +TVEW YAQS+T KP+KGMLTGPVTIL WSF R+D R KQ+ALA+RDEV Sbjct: 526 VSRPAPITVEWAKYAQSMTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEV 585 Query: 595 LDLEKAGVRIIQIDEAALREGLPLRKSQWKEYLDWAVESFRITANGVGDETQIHTHMCYS 654 DLE AG+ IIQIDE ALREGLPLR+S W YL W VE+FRI A D+TQIHTHMCY Sbjct: 586 ADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYC 645 Query: 655 EFNDIIASIADMDADVITIETSRSDMELLDAFDNFNYPNEIGPGVYDIHSPNIPTQEHIV 714 EFNDI+ SIA +DADVITIETSRSDMELL++F+ F+YPNEIGPGVYDIHSPN+P+ E I Sbjct: 646 EFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIE 705 Query: 715 QLMKKAAERIPVERLWVNPDCGLKTRQWAEVLPALGNMVAAARTLR 760 L+KKAA+RIP ERLWVNPDCGLKTR W E AL NMV AA+ LR Sbjct: 706 ALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLR 751