BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0005.0108.p         (146 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

PA5249 [E] COG1280 Putative threonine efflux protein Pae Pseudom...   102   2e-22
VC0136 [E] COG1280 Putative threonine efflux protein Vch Vibrio ...    98   6e-21
YPO3831 [E] COG1280 Putative threonine efflux protein Ype Yersin...    97   9e-21
ECs4754 [E] COG1280 Putative threonine efflux protein Ecs Escher...    96   4e-20
ZyigK [E] COG1280 Putative threonine efflux protein EcZ Escheric...    95   4e-20

>PA5249 [E] COG1280 Putative threonine efflux protein Pae Pseudomonas
           aeruginosa
          Length = 209

 Score =  102 bits (254), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 58/147 (39%), Positives = 81/147 (55%), Gaps = 10/147 (6%)

Query: 3   SEAAFNTIKILGAAYLIYLGWSQWRSPVHVDEAQAARPAAPAAWWQRTVT----GFLTNA 58
           S  AF+ IK  G AYL+YL   QW++P         RP        R +T    GFL NA
Sbjct: 68  SALAFSLIKWFGVAYLVYLAVRQWQAPPQALSTDGERPLG------RPLTLVLRGFLVNA 121

Query: 59  TNPKGIVFMVAVLPQFINHERSLWLQLLLMAITMVAVDLVVMHGYAFAASRMQRFFRDAK 118
           +NPK ++FM+AVLPQFI+  + L  Q L+M  TM+ VDL+VM GY   A+R+ R  R  +
Sbjct: 122 SNPKAVIFMLAVLPQFIDPHQPLLAQYLIMGGTMIVVDLIVMAGYTGLAARVLRVLRSPR 181

Query: 119 AVRMQNRFFGGVLMLVGAGLFFFKRSP 145
             ++ NR F  + +     L   +R+P
Sbjct: 182 QQKLVNRTFASLFVGAAGLLATVRRAP 208


>VC0136 [E] COG1280 Putative threonine efflux protein Vch Vibrio cholerae
          Length = 205

 Score = 98.2 bits (243), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 53/138 (38%), Positives = 77/138 (55%), Gaps = 5/138 (3%)

Query: 3   SEAAFNTIKILGAAYLIYLGWSQWRSPVHVDEAQAARPAAPAAWWQRTVTGFLTNATNPK 62
           S  AF  IK +GAAYL++LG  +WR    +     +   + AA  ++ V   L N TNPK
Sbjct: 68  SALAFTLIKWIGAAYLVWLGIQKWRDRAPLTATTTSHELSQAALLRKAV---LINLTNPK 124

Query: 63  GIVFMVAVLPQFINHERSLWLQLLLMAITMVAVDLVVMHGYAFAASRMQRFFRDAKAVRM 122
            IVF+VA+ PQFI+  R  W Q L++ IT V +D +VM GY   A+++ R+ R    +  
Sbjct: 125 SIVFLVALFPQFIDPTRDHWPQFLVLGITTVTIDAIVMFGYTALAAQLGRYIRSPNIMTR 184

Query: 123 QNRFFGGVLMLVGAGLFF 140
            N+ FG   M +G G+  
Sbjct: 185 MNKLFGS--MFMGCGMLL 200


>YPO3831 [E] COG1280 Putative threonine efflux protein Ype Yersinia pestis
          Length = 206

 Score = 97.4 bits (241), Expect = 9e-21,   Method: Compositional matrix adjust.
 Identities = 55/134 (41%), Positives = 80/134 (59%), Gaps = 3/134 (2%)

Query: 3   SEAAFNTIKILGAAYLIYLGWSQWRSPVHVDEAQAARPAAPAAWWQRTVTGFLTNATNPK 62
           S  AF  +K LGAAYLI+LG  QWR+   +D    A        ++R V     N TNPK
Sbjct: 68  SLLAFEILKWLGAAYLIWLGIQQWRAAGSLDLHALANSMPRRKLFKRAV---FVNLTNPK 124

Query: 63  GIVFMVAVLPQFINHERSLWLQLLLMAITMVAVDLVVMHGYAFAASRMQRFFRDAKAVRM 122
            IVF+ A+ PQF+  ++    Q L++  T V VD++VM GYA  A+R+ R+ +  + +++
Sbjct: 125 SIVFLAALFPQFVLPQQPQVAQYLILGSTSVIVDIIVMIGYATLATRIARWIKSPQQMKL 184

Query: 123 QNRFFGGVLMLVGA 136
            NR FGG+ ML+GA
Sbjct: 185 LNRIFGGLFMLIGA 198


>ECs4754 [E] COG1280 Putative threonine efflux protein Ecs Escherichia coli
           O157:H7
          Length = 206

 Score = 95.5 bits (236), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 53/134 (39%), Positives = 78/134 (58%), Gaps = 3/134 (2%)

Query: 3   SEAAFNTIKILGAAYLIYLGWSQWRSPVHVDEAQAARPAAPAAWWQRTVTGFLTNATNPK 62
           S  AF  +K  GAAYLI+LG  QWR+   +D    A   +    +QR V     N TNPK
Sbjct: 68  SVIAFEVLKWAGAAYLIWLGIQQWRAAGAIDLKSLASTQSRRHLFQRAV---FVNLTNPK 124

Query: 63  GIVFMVAVLPQFINHERSLWLQLLLMAITMVAVDLVVMHGYAFAASRMQRFFRDAKAVRM 122
            IVF+ A+ PQFI  ++   +Q +++ +T + VD++VM GYA  A R+  + +  K ++ 
Sbjct: 125 SIVFLAALFPQFIMPQQPQLMQYIVLGVTTIVVDIIVMIGYATLAQRIALWIKGPKQMKA 184

Query: 123 QNRFFGGVLMLVGA 136
            N+ FG + MLVGA
Sbjct: 185 LNKIFGSLFMLVGA 198


>ZyigK [E] COG1280 Putative threonine efflux protein EcZ Escherichia coli
           O157:H7 EDL933
          Length = 138

 Score = 95.1 bits (235), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 53/133 (39%), Positives = 78/133 (58%), Gaps = 3/133 (2%)

Query: 6   AFNTIKILGAAYLIYLGWSQWRSPVHVDEAQAARPAAPAAWWQRTVTGFLTNATNPKGIV 65
           AF  +K  GAAYLI+LG  QWR+   +D    A   +    +QR V     N TNPK IV
Sbjct: 3   AFEVLKWAGAAYLIWLGIQQWRAAGAIDLKSLASTQSRRHLFQRAV---FVNLTNPKSIV 59

Query: 66  FMVAVLPQFINHERSLWLQLLLMAITMVAVDLVVMHGYAFAASRMQRFFRDAKAVRMQNR 125
           F+ A+ PQFI  ++   +Q +++ +T + VD++VM GYA  A R+  + +  K ++  N+
Sbjct: 60  FLAALFPQFIMPQQPQLMQYIVLGVTTIVVDIIVMIGYATLAQRIALWIKGPKQMKALNK 119

Query: 126 FFGGVLMLVGAGL 138
            FG + MLVGA L
Sbjct: 120 IFGSLFMLVGALL 132