BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0077.p (294 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1223 [O] COG0330 Membrane protease subunits, stomatin/prohibi... 367 e-101 HI0150 [O] COG0330 Membrane protease subunits, stomatin/prohibit... 222 8e-58 PA4941 [O] COG0330 Membrane protease subunits, stomatin/prohibit... 221 2e-57 PM0118 [O] COG0330 Membrane protease subunits, stomatin/prohibit... 219 5e-57 XF0453 [O] COG0330 Membrane protease subunits, stomatin/prohibit... 204 2e-52 >RSc1223 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Rso Ralstonia solanacearum Length = 304 Score = 367 bits (942), Expect = e-101, Method: Compositional matrix adjust. Identities = 169/286 (59%), Positives = 231/286 (80%) Query: 1 MSRLITSIIAAVIAIWLVSTTIFVVEQRQSAIVFALGEVKQVVTEPGLHFKLPPPFQNVI 60 M+RLI++++A VIA+ ++S+ +FVV+QRQ A+VFA GE+KQV+ EPGLHFKLPPP QNVI Sbjct: 1 MNRLISALVALVIALAVLSSVVFVVDQRQYAVVFAFGEIKQVIKEPGLHFKLPPPLQNVI 60 Query: 61 YIDKRIQTLDTPDADRFITAEKKNVLVDSFVKWRIVDPRLYFISFGGDERRAQDRLSQIV 120 ++DKR+ T+D ADRFITAEKKN+LVD FVKWR+ DPRL+++SF GD R AQD ++Q + Sbjct: 61 FMDKRLMTIDVAGADRFITAEKKNLLVDWFVKWRVSDPRLFYVSFKGDNRLAQDSMTQKI 120 Query: 121 KAALNEEITKRTVREVISGERGKVMDAIQRKVATEAKQIGAEIIDVRLRRVDYVDQINNS 180 + +E +RTV +V+S +R VM +I + V + +G +IIDVRL+RVD + + S Sbjct: 121 NSIARDEFARRTVSDVVSTDREAVMQSILKGVQEYGRSVGVDIIDVRLKRVDLLASVTES 180 Query: 181 VYDRMKSERARVANELRSTGAAESEKIRADADRQRVVLLAEAYRDAEKIRGAGDAKASQV 240 VY RM++ER RVANELRSTGAAE EKIRADADRQR V+LA+AYR+A+KI+G GDA+A+ + Sbjct: 181 VYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLADAYREAQKIKGEGDARAADI 240 Query: 241 YAQAFGQNPEFFKFYRSLEAYRASFKNRHDLMVVDPNSEFFKYFKG 286 YA AFG++P+F F+RS+EAYRASF++R D+MV+ P S+FFK+ +G Sbjct: 241 YADAFGRDPQFAAFWRSMEAYRASFRDRKDVMVLQPGSDFFKFMRG 286 >HI0150 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Hin Haemophilus influenzae Length = 295 Score = 222 bits (565), Expect = 8e-58, Method: Compositional matrix adjust. Identities = 118/295 (40%), Positives = 195/295 (66%), Gaps = 14/295 (4%) Query: 1 MSRLITSIIAAVIAIWLVSTTIFVVEQRQSAIVFALGEV------KQVVTEPGLHFKLPP 54 M R + +I + A+ V ++I VV + I+ +V K VV EPGLHFK+P Sbjct: 1 MRRFLLPVIFVIAAV--VYSSIVVVTEGTRGIMLRFNKVQRDADNKVVVYEPGLHFKVPL 58 Query: 55 PFQNVIYIDKRIQTLDTPDADRFITAEKKNVLVDSFVKWRIVD-PRLYFISFGGDERRAQ 113 ++ +D RI+TLD A RF+T EKK++LVDS+VKW+I D R Y + GGD +A Sbjct: 59 -IDSIKVLDARIRTLDGS-ATRFVTVEKKDLLVDSYVKWKISDFGRFYTSTGGGDYAQAA 116 Query: 114 DRLSQIVKAALNEEITKRTVREVISGERGKVMDAIQRKVAT---EAKQIGAEIIDVRLRR 170 + LS+ V L EI RT+++++SG RG++M+ ++ +++ ++G E+IDVR+++ Sbjct: 117 NLLSRKVNDRLRSEIGSRTIKDIVSGTRGELMEGAKKALSSGQDSTAELGIEVIDVRVKQ 176 Query: 171 VDYVDQINNSVYDRMKSERARVANELRSTGAAESEKIRADADRQRVVLLAEAYRDAEKIR 230 ++ D++++S+Y RM++ER VA E RS G ++ I+AD DR+ ++LA A + A+++R Sbjct: 177 INLPDEVSSSIYQRMRAERDAVAREHRSQGKEKAAFIQADVDRKVTLILANANKTAQELR 236 Query: 231 GAGDAKASQVYAQAFGQNPEFFKFYRSLEAYRASFKNRHDLMVVDPNSEFFKYFK 285 G+GDA A+++Y+ AF Q P+FF F RSL+AY ASF N ++M++ P+S+FF++ + Sbjct: 237 GSGDAAAAKLYSDAFAQEPQFFTFVRSLKAYEASFANSDNIMILKPDSDFFRFMQ 291 >PA4941 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Pae Pseudomonas aeruginosa Length = 289 Score = 221 bits (562), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 127/282 (45%), Positives = 195/282 (69%), Gaps = 7/282 (2%) Query: 4 LITSIIAAVIAIWLVSTTIFVVEQRQSAIVFALGEVKQVVTEPGLHFKLPPPFQNVIYID 63 LI ++AA++ +W +++VV+Q + A++ G V + +PGLHFK+P Q V D Sbjct: 9 LIVGVVAAIV-LW---NSVYVVQQTERAVMLRFGRVVESDVKPGLHFKIPYVNQ-VRKFD 63 Query: 64 KRIQTLDTPDADRFITAEKKNVLVDSFVKWRIVDPRLYFISFGGDERRAQDRLSQIVKAA 123 R+ TLD P RF+T EKK V+VD++ KWR+ D ++ + G ++ A +RLS+ ++A Sbjct: 64 ARLLTLDAP-TQRFLTLEKKAVMVDAYAKWRVADAERFYTATSGLKQIADERLSRRLEAG 122 Query: 124 LNEEITKRTVREVISGERGKVMDAIQRKVATEA-KQIGAEIIDVRLRRVDYVDQINNSVY 182 L ++ KRT+ EV+SGER +M I + A K++G E+IDVR++ +D ++N SV+ Sbjct: 123 LRDQFGKRTLHEVVSGERDALMGDITASLNRMAQKELGIEVIDVRVKAIDLPKEVNRSVF 182 Query: 183 DRMKSERARVANELRSTGAAESEKIRADADRQRVVLLAEAYRDAEKIRGAGDAKASQVYA 242 +RM +ER R A E R+ G +E IRADADRQR V++AEAYR++E+ RG GD+KA+ +YA Sbjct: 183 ERMSTEREREAREHRAKGRELAEGIRADADRQRRVIVAEAYRESEETRGDGDSKAAAIYA 242 Query: 243 QAFGQNPEFFKFYRSLEAYRASFKNRHDLMVVDPNSEFFKYF 284 +A+ Q+PEF+ FYRSL+AYR SF + D++V+DP+SEFF+Y Sbjct: 243 KAYNQDPEFYSFYRSLKAYRESFAEKRDVLVLDPSSEFFRYL 284 >PM0118 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Pmu Pasteurella multocida Length = 295 Score = 219 bits (558), Expect = 5e-57, Method: Compositional matrix adjust. Identities = 118/296 (39%), Positives = 194/296 (65%), Gaps = 16/296 (5%) Query: 1 MSRLITSIIAAVIAIWLVSTTIFVVEQRQSAIVFALGEV------KQVVTEPGLHFKLPP 54 M + +T +I + AI + ++I +V + I+ +V K VV PGLHFK+P Sbjct: 1 MRKFLTPVIVVIAAI--LYSSIVIVSEGTRGIMLRFSKVHRDADNKVVVYNPGLHFKIP- 57 Query: 55 PFQNVIYI-DKRIQTLDTPDADRFITAEKKNVLVDSFVKWRIVD-PRLYFISFGGDERRA 112 F + I I D RI+TLD ADRF+T EKK++LVDS+VKWRI D R Y + GGD +A Sbjct: 58 -FIDSIKILDARIRTLDG-QADRFVTVEKKDLLVDSYVKWRISDFGRFYTATGGGDYAQA 115 Query: 113 QDRLSQIVKAALNEEITKRTVREVISGERGKVMDAIQRKVAT---EAKQIGAEIIDVRLR 169 + L + V L E RT+++++SG RG++M+ ++ + T ++G E++DVR++ Sbjct: 116 SNLLRRKVNDRLRSETGSRTIKDIVSGTRGELMEGARKALNTGPDSTAELGIEVVDVRVK 175 Query: 170 RVDYVDQINNSVYDRMKSERARVANELRSTGAAESEKIRADADRQRVVLLAEAYRDAEKI 229 +++ D++++S+Y RM++ER VA E RS G ++ I+AD DR+ ++LA A R A+++ Sbjct: 176 QINLPDEVSSSIYQRMRAERDAVAREHRSQGREKAAFIQADVDRKVTLILANANRTAQEL 235 Query: 230 RGAGDAKASQVYAQAFGQNPEFFKFYRSLEAYRASFKNRHDLMVVDPNSEFFKYFK 285 RG+GDA A++V++ AF Q P+F+ F RSL+AY +SF N ++M++ P+S+FF++ + Sbjct: 236 RGSGDATAAKVFSDAFSQEPQFYSFLRSLKAYESSFANSDNMMILKPDSDFFRFMQ 291 >XF0453 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Xfa Xylella fastidiosa 9a5c Length = 287 Score = 204 bits (519), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 115/287 (40%), Positives = 185/287 (64%), Gaps = 5/287 (1%) Query: 1 MSRLITSIIAAVIAIWLVSTTIFVVEQRQSAIVFALGEVKQVVTEPGLHFKLPPPFQNVI 60 M + ++ AV+ + L S+ IFVV + Q+A+V LG V + + GLHFK+P ++V Sbjct: 1 MKNYLWIVVTAVLFLSLFSS-IFVVREDQTAMVINLGRVVRYDLKSGLHFKIPL-VESVR 58 Query: 61 YIDKRIQTLDTPDADRFITAEKKNVLVDSFVKWRIVDPRLYFISFGGDERRAQDRLSQIV 120 D+R + + T A R+ TAE+K+V VD F I D R ++ + GGDE +A RL+ I+ Sbjct: 59 LFDRRFKVMATEPA-RYFTAEQKDVSVDFFAIGYIEDVRSFYRATGGDESQAAARLAPII 117 Query: 121 KAALNEEITKRTVREVISGERGKVMDAIQRKVATEAKQIGAEIIDVRLRRVDY-VD-QIN 178 +L +I RT++E++SG+R +++ + + K +G I+D+R+++++ VD Q+ Sbjct: 118 TDSLRNQINSRTLQELVSGDRSELIAGQLKSINAATKGLGVHIVDLRIKQIELPVDSQVI 177 Query: 179 NSVYDRMKSERARVANELRSTGAAESEKIRADADRQRVVLLAEAYRDAEKIRGAGDAKAS 238 + VY+RM+++R + A +LR+ G S IRA ADR+ VL+A+A RDA+K+RG GDA+A+ Sbjct: 178 SDVYERMRAQRKQEAAKLRAEGEERSLSIRAQADRESTVLIADAERDAQKLRGEGDAEAA 237 Query: 239 QVYAQAFGQNPEFFKFYRSLEAYRASFKNRHDLMVVDPNSEFFKYFK 285 +VY QA +P F+ FYRSLEAYR + + ++V+D N F KYFK Sbjct: 238 RVYGQAGANDPAFYAFYRSLEAYRNGMADGNGVIVLDKNDPFLKYFK 284