BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0072.p (170 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1219 [R] COG1160 Predicted GTPases Rso Ralstonia solanacearum 273 1e-73 NMB0852 [R] COG1160 Predicted GTPases Nme Neisseria meningitidis... 233 2e-61 NMA1063 [R] COG1160 Predicted GTPases NmA Neisseria meningitidis... 232 3e-61 VC0763 [R] COG1160 Predicted GTPases Vch Vibrio cholerae 182 3e-46 YPO2875 [R] COG1160 Predicted GTPases Ype Yersinia pestis 170 2e-42 >RSc1219 [R] COG1160 Predicted GTPases Rso Ralstonia solanacearum Length = 447 Score = 273 bits (699), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 131/159 (82%), Positives = 143/159 (89%) Query: 1 MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPFLVIDTGGF 60 MKPVIALVGRPNVGKSTLFNRLTRSRDALVAD+PGLTRDRHYGEGRVGERPF+ IDTGGF Sbjct: 1 MKPVIALVGRPNVGKSTLFNRLTRSRDALVADMPGLTRDRHYGEGRVGERPFIAIDTGGF 60 Query: 61 EPVAKEGIMFEMAKQTKQAVVEADVVIFIVDGRQGLTPHDKTITDFLRKSGRSVMLVVNK 120 EPVAKEGI+ EMAKQT+QAVVEADVVIFIVDGR GL P D+ I D+LRK+GR ++L VNK Sbjct: 61 EPVAKEGIVAEMAKQTRQAVVEADVVIFIVDGRLGLAPQDRVIADYLRKTGRRILLAVNK 120 Query: 121 AEGMKYTSVTADFYELGLGDPYVISAAHGDGVADLVXRA 159 AEGMKYT+V DFYELGLGDP IS+AHGDGV +LV A Sbjct: 121 AEGMKYTAVATDFYELGLGDPRAISSAHGDGVRELVDEA 159 Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 48/125 (38%), Positives = 76/125 (60%), Gaps = 8/125 (6%) Query: 5 IALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPFLVIDTGGFEPVA 64 IA+VGRPNVGKSTL N L + D+PG TRD Y + +P+ +IDT G Sbjct: 183 IAIVGRPNVGKSTLVNALIGEERVIAFDMPGTTRDAIYVDFERNGKPYTLIDTAGLR--- 239 Query: 65 KEGIMFEMAK-----QTKQAVVEADVVIFIVDGRQGLTPHDKTITDFLRKSGRSVMLVVN 119 K G +FE + +T Q++ +A+VV+ ++D +Q ++ D I F+ +SGR++++ VN Sbjct: 240 KRGKVFEAIEKFSVVKTLQSIADANVVVLLLDAQQDISDQDAHIAGFIVESGRALVIGVN 299 Query: 120 KAEGM 124 K +G+ Sbjct: 300 KWDGL 304 >NMB0852 [R] COG1160 Predicted GTPases Nme Neisseria meningitidis MC58 Length = 485 Score = 233 bits (593), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 114/165 (69%), Positives = 127/165 (76%) Query: 1 MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPFLVIDTGGF 60 MKP IALVGRPNVGKSTLFNRLTR++DALV DLPGLTRDRHYG G+VG +P+LVIDTGGF Sbjct: 1 MKPTIALVGRPNVGKSTLFNRLTRTKDALVHDLPGLTRDRHYGHGKVGSKPYLVIDTGGF 60 Query: 61 EPVAKEGIMFEMAKQTKQAVVEADVVIFIVDGRQGLTPHDKTITDFLRKSGRSVMLVVNK 120 EPV GI+ EMAKQT QAV EAD V+F+VDGR GLTP DK I D LR+S R V L VNK Sbjct: 61 EPVVDSGILHEMAKQTLQAVDEADAVVFLVDGRTGLTPQDKIIADRLRQSPRPVYLAVNK 120 Query: 121 AEGMKYTSVTADFYELGLGDPYVISAAHGDGVADLVXRAASRSPS 165 EG + A+FYEL LGDPYVIS AHGDGV L+ + P Sbjct: 121 GEGGNRAVLAAEFYELALGDPYVISGAHGDGVYYLIEDILEKFPE 165 Score = 78.2 bits (191), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 54/182 (29%), Positives = 87/182 (47%), Gaps = 19/182 (10%) Query: 3 PVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPFLVIDTGGF-- 60 PV A++GRPNVGKSTL N + + D+ G TRD + + +PF +IDT G Sbjct: 176 PVFAVIGRPNVGKSTLVNAILGEERVITFDMAGTTRDSIHIDFEREGKPFTIIDTAGVRR 235 Query: 61 -----EPVAKEGIMFEMAKQTKQAVVEADVVIFIVDGRQGLTPHDKTITDFLRKSGRSVM 115 E V K ++ M QAV A+V + ++D +Q + D TI F ++GR+++ Sbjct: 236 RGKVDEAVEKFSVIKAM-----QAVEAANVAVLVLDAQQDIADQDATIAGFALEAGRALV 290 Query: 116 LVVNKAEGMKYT-------SVTADFYELGLGDPYVISAAHGDGVADLVXRAASRSPSSAV 168 + VNK +G+ + Y L + ISA G+ L + ++ + Sbjct: 291 VAVNKWDGISEERREQVKRDINRKLYFLDFAKFHFISALKERGIDGLFDSIQAAYNAAMI 350 Query: 169 RM 170 +M Sbjct: 351 KM 352 >NMA1063 [R] COG1160 Predicted GTPases NmA Neisseria meningitidis Z2491 Length = 485 Score = 232 bits (591), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 113/156 (72%), Positives = 125/156 (80%) Query: 1 MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPFLVIDTGGF 60 MKP IALVGRPNVGKSTLFNRLTR++DALV DLPGLTRDRHYG G+VG +P+LVIDTGGF Sbjct: 1 MKPTIALVGRPNVGKSTLFNRLTRTKDALVHDLPGLTRDRHYGHGKVGSKPYLVIDTGGF 60 Query: 61 EPVAKEGIMFEMAKQTKQAVVEADVVIFIVDGRQGLTPHDKTITDFLRKSGRSVMLVVNK 120 EPV GI+ EMAKQT QAV EAD V+F+VDGR GLTP DK I D LR+S R V L VNK Sbjct: 61 EPVVDSGILHEMAKQTLQAVDEADAVVFLVDGRTGLTPQDKIIADRLRQSPRPVYLAVNK 120 Query: 121 AEGMKYTSVTADFYELGLGDPYVISAAHGDGVADLV 156 EG + A+FYEL LGDPYVIS AHGDGV L+ Sbjct: 121 GEGGNRAVLAAEFYELALGDPYVISGAHGDGVYYLI 156 Score = 78.2 bits (191), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 54/182 (29%), Positives = 87/182 (47%), Gaps = 19/182 (10%) Query: 3 PVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPFLVIDTGGF-- 60 PV A++GRPNVGKSTL N + + D+ G TRD + + +PF +IDT G Sbjct: 176 PVFAVIGRPNVGKSTLVNAILGEERVIAFDMAGTTRDSIHIDFEREGKPFTIIDTAGVRR 235 Query: 61 -----EPVAKEGIMFEMAKQTKQAVVEADVVIFIVDGRQGLTPHDKTITDFLRKSGRSVM 115 E V K ++ M QAV A+V + ++D +Q + D TI F ++GR+++ Sbjct: 236 RGKVDEAVEKFSVIKAM-----QAVEAANVAVLVLDAQQDIADQDATIAGFALEAGRALV 290 Query: 116 LVVNKAEGMKYT-------SVTADFYELGLGDPYVISAAHGDGVADLVXRAASRSPSSAV 168 + VNK +G+ + Y L + ISA G+ L + ++ + Sbjct: 291 VAVNKWDGISEERREQVKRDINRKLYFLDFAKFHFISALKERGIDGLFDSIQAAYNAAMI 350 Query: 169 RM 170 +M Sbjct: 351 KM 352 >VC0763 [R] COG1160 Predicted GTPases Vch Vibrio cholerae Length = 494 Score = 182 bits (462), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 90/158 (56%), Positives = 120/158 (75%), Gaps = 1/158 (0%) Query: 1 MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPFLVIDTGGF 60 M PV+ALVGRPNVGKSTLFNRLTR+RDALVAD PGLTRDR YG+ ++GE F+VIDTGG Sbjct: 1 MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGQAKLGEHEFIVIDTGGI 60 Query: 61 EPVAKEGIMFEMAKQTKQAVVEADVVIFIVDGRQGLTPHDKTITDFLRKSGRSVMLVVNK 120 + ++EG+ +MA+Q+ A+ EADVV+F+VDGR GLT D+ I LR+ + +LVVNK Sbjct: 61 DG-SEEGVETKMAQQSLAAIDEADVVLFMVDGRAGLTVADEAIAQHLRRIEKPAILVVNK 119 Query: 121 AEGMKYTSVTADFYELGLGDPYVISAAHGDGVADLVXR 158 +G+ + +A+F++LG+ Y I+AAHG GV L+ R Sbjct: 120 VDGIDADAASAEFWQLGMDQMYQIAAAHGRGVGALIDR 157 Score = 95.1 bits (235), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 67/180 (37%), Positives = 99/180 (55%), Gaps = 21/180 (11%) Query: 5 IALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPFLVIDTGGF---- 60 +A++GRPNVGKSTL NR+ +V D+PG TRD Y + ER +++IDT G Sbjct: 208 LAIIGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMKRDEREYVLIDTAGVRRRK 267 Query: 61 ---EPVAKEGIMFEMAKQTKQAVVEADVVIFIVDGRQGLTPHDKTITDFLRKSGRSVMLV 117 E V K F + K T QA+ +A+VV+ +VD R+ ++ D ++ F SGRS+++ Sbjct: 268 RINETVEK----FSVVK-TLQAIEDANVVLLVVDARENISDQDLSLLGFALNSGRSIVIA 322 Query: 118 VNKAEGMKY---TSVTADF-YELGLGD---PYVISAAHGDGVADLVX--RAASRSPSSAV 168 VNK +G+ + V + LG D + ISA HG GV L + A RS ++ V Sbjct: 323 VNKWDGLSFDVKEHVKKELDRRLGFVDFARIHFISALHGTGVGHLFESVQEAYRSATTRV 382 >YPO2875 [R] COG1160 Predicted GTPases Ype Yersinia pestis Length = 495 Score = 170 bits (430), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 86/156 (55%), Positives = 110/156 (70%), Gaps = 1/156 (0%) Query: 1 MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPFLVIDTGGF 60 M PVIALVGRPNVGKSTLFNRLT +RDALVAD PGLTRDR YG V F+V+DTGG Sbjct: 1 MIPVIALVGRPNVGKSTLFNRLTHTRDALVADFPGLTRDRKYGRAEVEGHEFIVVDTGGI 60 Query: 61 EPVAKEGIMFEMAKQTKQAVVEADVVIFIVDGRQGLTPHDKTITDFLRKSGRSVMLVVNK 120 + ++G+ +MA Q+ A+ EAD+V+F+VD R GL P D+ I LR ++ LV NK Sbjct: 61 DG-TEDGVETKMAGQSLLAIEEADIVLFMVDARAGLMPADQGIAQHLRSREKATFLVANK 119 Query: 121 AEGMKYTSVTADFYELGLGDPYVISAAHGDGVADLV 156 +G+ + TADFY LGLG+ + I+A+HG GV L+ Sbjct: 120 TDGIDPDTATADFYSLGLGEVHAIAASHGRGVTQLI 155 Score = 98.2 bits (243), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 62/163 (38%), Positives = 95/163 (58%), Gaps = 15/163 (9%) Query: 5 IALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPFLVIDTGGFEPVA 64 +A+VGRPNVGKSTL NR+ +V D+PG TRD Y +R +++IDT G V Sbjct: 210 LAIVGRPNVGKSTLTNRILGEDRVVVYDMPGTTRDSIYIPMTRDDREYILIDTAG---VR 266 Query: 65 KEGIMFEMAK-----QTKQAVVEADVVIFIVDGRQGLTPHDKTITDFLRKSGRSVMLVVN 119 K G + E + +T QA+ +++VV+ ++D R G++ D ++ F+ SGRS+++ VN Sbjct: 267 KRGKITETVEKFSVIKTLQAIEDSNVVLLVIDARDGISDQDLSLLGFILNSGRSLVIAVN 326 Query: 120 KAEGM--KYTSVTADFYELGLG-----DPYVISAAHGDGVADL 155 K +GM + + D +L LG + ISA HG GV +L Sbjct: 327 KWDGMTEEARAQVKDMLDLRLGFVDFARIHFISALHGSGVGNL 369