BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0068.p (422 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1215 [I] COG0821 Enzyme involved in the deoxyxylulose pathway... 705 0.0 NMA1524 [I] COG0821 Enzyme involved in the deoxyxylulose pathway... 577 e-164 NMB1310 [I] COG0821 Enzyme involved in the deoxyxylulose pathway... 577 e-164 XF2575 [I] COG0821 Enzyme involved in the deoxyxylulose pathway ... 556 e-158 BMEI0269 [I] COG0821 Enzyme involved in the deoxyxylulose pathwa... 550 e-156 >RSc1215 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Rso Ralstonia solanacearum Length = 431 Score = 705 bits (1819), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/411 (83%), Positives = 370/411 (90%) Query: 7 PIASGPLGRRQSRRAVIRYGEREVAVGGGAPVMVQSMTNTDTADAIGTAIQIKDLARAGS 66 P GPL RR SR A IR+GER V VGG APV VQSMTNTDTADAIGTAIQ+K+LAR GS Sbjct: 11 PALPGPLPRRHSRAAEIRWGERLVRVGGDAPVCVQSMTNTDTADAIGTAIQVKELARTGS 70 Query: 67 EVVRITVNSPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLNDYPDCAKALSKYRIN 126 E+VRITVN+PEAAAAVPAIREQLDRMG+DVPLVGDFHYNGH LL D+P CA+ALSKYRIN Sbjct: 71 ELVRITVNTPEAAAAVPAIREQLDRMGIDVPLVGDFHYNGHKLLQDHPACAEALSKYRIN 130 Query: 127 PGNVGKGAKRDSQFAQMIEAACRYDKPVRIGVNWGSLDQALLARIMDENAGRAEPWPAQA 186 PGNVG+GAKRD+QFAQMIE ACRY KPVRIGVNWGSLDQ LLARIMDENA RA PW A+A Sbjct: 131 PGNVGQGAKRDTQFAQMIETACRYGKPVRIGVNWGSLDQDLLARIMDENAQRAAPWDARA 190 Query: 187 VMYEALVTSAIENAQRAEELGLAGDKIILSCKVSGVQDLIAVYRELARRCDYPLHLGLTE 246 VM EAL+TSAIE+A++AEE+GL G +IILSCKVS VQDLIAVYRELARRCDY LHLGLTE Sbjct: 191 VMIEALITSAIESARKAEEIGLPGSQIILSCKVSAVQDLIAVYRELARRCDYALHLGLTE 250 Query: 247 AGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQTMGLRKFTP 306 AGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPG R +EVIV QEILQTMGLR FTP Sbjct: 251 AGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGAPREKEVIVAQEILQTMGLRNFTP 310 Query: 307 MVIACPGCGRTTSTVFQDLADKIQTYLREQMPQWKGVYPGVESMNVAVMGCIVNGPGESK 366 MVIACPGCGRTTSTVFQ+LA +IQ+YLREQMP WK YPGVE MNVAVMGCIVNGPGESK Sbjct: 311 MVIACPGCGRTTSTVFQELAARIQSYLREQMPVWKTQYPGVEDMNVAVMGCIVNGPGESK 370 Query: 367 HANIGISLPGTGESPAAPVFIDGEKRMTLRGERIAEEFQTIVLDYVQTHYG 417 HANIGISLPGTGESPAAPVF+DG K TLRGERIAE+FQ IV +YV+THYG Sbjct: 371 HANIGISLPGTGESPAAPVFVDGVKVKTLRGERIAEDFQVIVDEYVRTHYG 421 >NMA1524 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis NmA Neisseria meningitidis Z2491 Length = 421 Score = 577 bits (1488), Expect = e-164, Method: Compositional matrix adjust. Identities = 279/407 (68%), Positives = 330/407 (81%), Gaps = 4/407 (0%) Query: 13 LGRRQSRRAVIRYGEREVAVGGGAPVMVQSMTNTDTADAIGTAIQIKDLARAGSEVVRIT 72 L RR++ + I + + VG APV++QSMTNTDTADA TA+QIK+L+ AGSE+VRIT Sbjct: 4 LQRRKTHQVRIDH----ITVGSEAPVVIQSMTNTDTADAKATALQIKELSDAGSEMVRIT 59 Query: 73 VNSPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLNDYPDCAKALSKYRINPGNVGK 132 VNSPEAA+ V IR +LD MG PL+GDFH+NG LL ++P+C KALSKYRINPGNVGK Sbjct: 60 VNSPEAASKVAEIRRRLDDMGYATPLIGDFHFNGERLLAEFPECGKALSKYRINPGNVGK 119 Query: 133 GAKRDSQFAQMIEAACRYDKPVRIGVNWGSLDQALLARIMDENAGRAEPWPAQAVMYEAL 192 G K D +FA MI A DK VRIGVNWGSLDQ+L R+MD N + P P + V EAL Sbjct: 120 GVKGDEKFAFMIRTAAENDKAVRIGVNWGSLDQSLAKRMMDANLASSAPKPPEEVTKEAL 179 Query: 193 VTSAIENAQRAEELGLAGDKIILSCKVSGVQDLIAVYRELARRCDYPLHLGLTEAGMGSK 252 + SA+E+A++A LGL DKIILSCKVS VQDLI VYREL RC YPLHLGLTEAGMGSK Sbjct: 180 IVSALESAEKAVLLGLPEDKIILSCKVSAVQDLIQVYRELGSRCAYPLHLGLTEAGMGSK 239 Query: 253 GIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQTMGLRKFTPMVIACP 312 GIVASTAALSVLLQEGIGDTIRISLTPEPG RT+EV+VGQEILQTMGLR FTPMV ACP Sbjct: 240 GIVASTAALSVLLQEGIGDTIRISLTPEPGSPRTQEVVVGQEILQTMGLRSFTPMVTACP 299 Query: 313 GCGRTTSTVFQDLADKIQTYLREQMPQWKGVYPGVESMNVAVMGCIVNGPGESKHANIGI 372 GCGRTTSTVFQ+LA +Q YLR++M W+ +YPGVES+NVAVMGC+VNGPGESK A+IGI Sbjct: 300 GCGRTTSTVFQELAQDVQNYLRQKMSIWRTLYPGVESLNVAVMGCVVNGPGESKLADIGI 359 Query: 373 SLPGTGESPAAPVFIDGEKRMTLRGERIAEEFQTIVLDYVQTHYGKQ 419 SLPGTGE+P APV++DGE+++TL+G+ IA EF IV +YV+T+YG+ Sbjct: 360 SLPGTGETPVAPVYVDGERKVTLKGDNIATEFLAIVEEYVKTNYGEN 406 >NMB1310 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Nme Neisseria meningitidis MC58 Length = 421 Score = 577 bits (1486), Expect = e-164, Method: Compositional matrix adjust. Identities = 279/407 (68%), Positives = 330/407 (81%), Gaps = 4/407 (0%) Query: 13 LGRRQSRRAVIRYGEREVAVGGGAPVMVQSMTNTDTADAIGTAIQIKDLARAGSEVVRIT 72 L RR++ + I + + VG APV++QSMTNTDTADA TA+QIK+L+ AGSE+VRIT Sbjct: 4 LQRRKTHQVRIDH----ITVGSEAPVVIQSMTNTDTADAKATALQIKELSDAGSEMVRIT 59 Query: 73 VNSPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLNDYPDCAKALSKYRINPGNVGK 132 VNSPEAA+ V IR +LD MG PL+GDFH+NG LL ++P+C KALSKYRINPGNVGK Sbjct: 60 VNSPEAASKVAEIRRRLDDMGYATPLIGDFHFNGERLLAEFPECGKALSKYRINPGNVGK 119 Query: 133 GAKRDSQFAQMIEAACRYDKPVRIGVNWGSLDQALLARIMDENAGRAEPWPAQAVMYEAL 192 G K D +FA MI A DK VRIGVNWGSLDQ+L R+MD N + P P + V EAL Sbjct: 120 GVKGDEKFAFMIRTAAENDKAVRIGVNWGSLDQSLAKRMMDANLASSAPKPPEEVTKEAL 179 Query: 193 VTSAIENAQRAEELGLAGDKIILSCKVSGVQDLIAVYRELARRCDYPLHLGLTEAGMGSK 252 + SA+E+A++A LGL DKIILSCKVS VQDLI VYREL RC YPLHLGLTEAGMGSK Sbjct: 180 IVSALESAEKAVLLGLPEDKIILSCKVSAVQDLIQVYRELGSRCAYPLHLGLTEAGMGSK 239 Query: 253 GIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQTMGLRKFTPMVIACP 312 GIVASTAALSVLLQEGIGDTIRISLTPEPG RT+EV+VGQEILQTMGLR FTPMV ACP Sbjct: 240 GIVASTAALSVLLQEGIGDTIRISLTPEPGSPRTQEVVVGQEILQTMGLRSFTPMVTACP 299 Query: 313 GCGRTTSTVFQDLADKIQTYLREQMPQWKGVYPGVESMNVAVMGCIVNGPGESKHANIGI 372 GCGRTTSTVFQ+LA +Q YLR++M W+ +YPGVES+NVAVMGC+VNGPGESK A+IGI Sbjct: 300 GCGRTTSTVFQELAQDVQNYLRQKMSIWRTLYPGVESLNVAVMGCVVNGPGESKLADIGI 359 Query: 373 SLPGTGESPAAPVFIDGEKRMTLRGERIAEEFQTIVLDYVQTHYGKQ 419 SLPGTGE+P APV++DGE+++TL+G+ IA EF IV +YV+T+YG+ Sbjct: 360 SLPGTGETPVAPVYVDGERKVTLKGDNIATEFLAIVEEYVKTNYGEN 406 >XF2575 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Xfa Xylella fastidiosa 9a5c Length = 417 Score = 556 bits (1432), Expect = e-158, Method: Compositional matrix adjust. Identities = 267/407 (65%), Positives = 325/407 (79%), Gaps = 4/407 (0%) Query: 12 PLGRRQSRRAVIRYGEREVAVGGGAPVMVQSMTNTDTADAIGTAIQIKDLARAGSEVVRI 71 P RR+++ I + V VGGG PV+VQSMTNTDTAD + + Q+ +L RAGSE+VR+ Sbjct: 12 PWPRRRTQAVNIGH----VTVGGGHPVVVQSMTNTDTADVVASTKQVAELWRAGSEMVRL 67 Query: 72 TVNSPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLNDYPDCAKALSKYRINPGNVG 131 TVN+ ++AAA+P I E+L MG+DVPL+GDFHYNGH LL D P CA+ L+KYRINPGNVG Sbjct: 68 TVNNAQSAAAIPRIAERLAMMGIDVPLIGDFHYNGHQLLADEPACAEVLAKYRINPGNVG 127 Query: 132 KGAKRDSQFAQMIEAACRYDKPVRIGVNWGSLDQALLARIMDENAGRAEPWPAQAVMYEA 191 G KRD QF Q+IE A RY KP+RIG NWGSLDQ L A++MDEN R +PW A V+ E Sbjct: 128 FGKKRDLQFGQLIECAIRYGKPIRIGANWGSLDQMLAAQLMDENNRRKQPWDAAQVLREV 187 Query: 192 LVTSAIENAQRAEELGLAGDKIILSCKVSGVQDLIAVYRELARRCDYPLHLGLTEAGMGS 251 L+ SA+ +A+RA ELGL D+I+LS KVSGVQ+LIAVYR++A RCD+ LHLGLTEAG+GS Sbjct: 188 LICSAVGSAERAVELGLPRDRIVLSAKVSGVQELIAVYRDMAARCDFALHLGLTEAGIGS 247 Query: 252 KGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQTMGLRKFTPMVIAC 311 KGIVAS+AAL+VLLQEGIGDTIRISLTPEPG RT+EVIV QE+LQT G R FTPMV AC Sbjct: 248 KGIVASSAALAVLLQEGIGDTIRISLTPEPGQSRTQEVIVAQELLQTTGHRAFTPMVTAC 307 Query: 312 PGCGRTTSTVFQDLADKIQTYLREQMPQWKGVYPGVESMNVAVMGCIVNGPGESKHANIG 371 PGCGRTTS FQ+LA +Q ++R++M WK +PG E+M +AVMGC+VNGPGES+HANIG Sbjct: 308 PGCGRTTSEFFQELAKTVQQHVRDKMQVWKITHPGAETMTLAVMGCVVNGPGESRHANIG 367 Query: 372 ISLPGTGESPAAPVFIDGEKRMTLRGERIAEEFQTIVLDYVQTHYGK 418 ISLPGTGE P APVFIDGEK +TLRGE IA++F +V DYV+ Y + Sbjct: 368 ISLPGTGEMPVAPVFIDGEKSVTLRGENIAQDFIALVDDYVERRYAR 414 >BMEI0269 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Bme Brucella melitensis Length = 437 Score = 550 bits (1416), Expect = e-156, Method: Compositional matrix adjust. Identities = 274/417 (65%), Positives = 322/417 (77%), Gaps = 4/417 (0%) Query: 1 MSSSPFPIASGPLGRRQSRRAVIRYGEREVAVGGGAPVMVQSMTNTDTADAIGTAIQIKD 60 MSS S P RRQS + + APV+VQSMTNTDTAD T Q+ Sbjct: 18 MSSETVSYFSHPFPRRQSVGVSVGGVIVGGS----APVVVQSMTNTDTADVDSTVAQVAA 73 Query: 61 LARAGSEVVRITVNSPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLNDYPDCAKAL 120 L RAGSE+VRITV+ E+AAAVP IRE+L+R+G DVPLVGDFHY GH LL D+P CA+AL Sbjct: 74 LHRAGSEIVRITVDRDESAAAVPKIRERLERLGHDVPLVGDFHYIGHKLLADHPACAEAL 133 Query: 121 SKYRINPGNVGKGAKRDSQFAQMIEAACRYDKPVRIGVNWGSLDQALLARIMDENAGRAE 180 +KYRINPGNVG K+D QFA ++E A RYDKPVRIGVNWGSLDQ LL +MD N Sbjct: 134 AKYRINPGNVGFKDKKDKQFADIVEMAIRYDKPVRIGVNWGSLDQELLTTLMDRNQAEGA 193 Query: 181 PWPAQAVMYEALVTSAIENAQRAEELGLAGDKIILSCKVSGVQDLIAVYRELARRCDYPL 240 P AQ VM EA+V SA+ +A AEE+GL DKIILS KVS VQDLIAVY LA+R ++ L Sbjct: 194 PLSAQDVMREAIVQSALISANLAEEIGLGRDKIILSAKVSQVQDLIAVYTMLAQRSNHAL 253 Query: 241 HLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQTMG 300 HLGLTEAGMG+KGIVAS+AA+ +LLQ+GIGDTIRISLTPEPGGDRTREV V QE+LQTMG Sbjct: 254 HLGLTEAGMGTKGIVASSAAMGILLQQGIGDTIRISLTPEPGGDRTREVQVAQELLQTMG 313 Query: 301 LRKFTPMVIACPGCGRTTSTVFQDLADKIQTYLREQMPQWKGVYPGVESMNVAVMGCIVN 360 R+F P+V ACPGCGRTTSTVFQ+LA IQ +R MP W+ YPGVE+++VAVMGCIVN Sbjct: 314 FRQFVPIVAACPGCGRTTSTVFQELAQTIQEDIRRNMPLWREKYPGVEALSVAVMGCIVN 373 Query: 361 GPGESKHANIGISLPGTGESPAAPVFIDGEKRMTLRGERIAEEFQTIVLDYVQTHYG 417 GPGESKHA+IGISLPGTGE+P+APVF+DG+K TLRG IAE+FQ +V DY++ +G Sbjct: 374 GPGESKHADIGISLPGTGETPSAPVFVDGKKVTTLRGPGIAEDFQKMVADYIENRFG 430