BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0166.p (643 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll2589 [GEPR] COG0477 Permeases of the major facilitator superf... 384 e-106 AGl781 [GEPR] COG0477 Permeases of the major facilitator superfa... 267 7e-71 BMEII1119 [GEPR] COG0477 Permeases of the major facilitator supe... 265 2e-70 mll2590 [V] COG1566 Multidrug resistance efflux pump Mlo Mesorhi... 263 9e-70 mlr4819 [GEPR] COG0477 Permeases of the major facilitator superf... 261 3e-69 >mll2589 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 518 Score = 384 bits (987), Expect = e-106, Method: Compositional matrix adjust. Identities = 179/303 (59%), Positives = 225/303 (74%) Query: 327 IVQRXGWLARVMSTRWLFSASAVGFTIASMLCGLAWDINSMIFFRALQGFLGGSMIPMVF 386 ++ GWL RV STRWLF+ SA GFT+ASMLCG AW I SMI FRALQG LG SMIP VF Sbjct: 64 VIPLSGWLTRVFSTRWLFTISAAGFTLASMLCGFAWSIESMIVFRALQGLLGASMIPTVF 123 Query: 387 TSAFFYFSGHQRVIAAATVGALSSLAPTLGPTVGGWITSNYSWHWLFFINLAPGIFVAVV 446 TS+F YF G +RV AAA VG+++S+APTLGP +GGWIT +WHWLF++N+ PG + ++ Sbjct: 124 TSSFHYFQGPRRVYAAAVVGSIASIAPTLGPVIGGWITDTLNWHWLFYVNVIPGTIITIL 183 Query: 447 VPMLVRIDKPNLSLLRGADYLGMILLAASLGCLEYSLEEGPRLGWMGDDIIRTTVWIAIV 506 V +LV+IDK + SLL+GADY+G++L+A SLG EY LEEG R W D IR +A + Sbjct: 184 VAVLVKIDKADPSLLKGADYIGIVLMAVSLGTAEYVLEEGSRWNWFDDATIRNGAIVAGI 243 Query: 507 AGVGFIWRSLAYDNPVVDLRALKDRNFALGCFFSFVTGIGIFATVYLTPVFLAHVRGFSA 566 V F+ RSL Y PVVD RA +RNFA+GCF SFVTGIGIFAT+YLTP+FL +VRG+ A Sbjct: 244 TMVLFVIRSLTYSQPVVDFRAFGNRNFAIGCFLSFVTGIGIFATIYLTPLFLGYVRGYDA 303 Query: 567 LDIGLAIFATGLFQICAIPFYTYLGRRVDLRWLMMFGMACFALSMWNFTPITHDWGWREL 626 L GLA+F+TG+ + +P Y +L +R D RWLMMFG+A F SMW+F+ IT WG EL Sbjct: 304 LQTGLAVFSTGVASMVGVPVYIFLAKRFDTRWLMMFGLASFGASMWSFSAITSQWGAAEL 363 Query: 627 LLP 629 L+P Sbjct: 364 LIP 366 >AGl781 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 527 Score = 267 bits (682), Expect = 7e-71, Method: Compositional matrix adjust. Identities = 132/303 (43%), Positives = 188/303 (62%) Query: 327 IVQRXGWLARVMSTRWLFSASAVGFTIASMLCGLAWDINSMIFFRALQGFLGGSMIPMVF 386 ++ G LAR++STR LF+ A GFT++S LC A +I+ MI +RA+QGF+GG MIP VF Sbjct: 76 MIPLSGTLARILSTRVLFATCAAGFTLSSALCATATNIDQMIVYRAIQGFIGGGMIPSVF 135 Query: 387 TSAFFYFSGHQRVIAAATVGALSSLAPTLGPTVGGWITSNYSWHWLFFINLAPGIFVAVV 446 +AF F +R + + +G +++LAPT+GPTVGG++++ +SWHWLF +N+ PGI V ++ Sbjct: 136 AAAFTIFPPSKRSVVSPIIGLVATLAPTIGPTVGGYLSNAFSWHWLFLVNIIPGIIVTIL 195 Query: 447 VPMLVRIDKPNLSLLRGADYLGMILLAASLGCLEYSLEEGPRLGWMGDDIIRTTVWIAIV 506 L+ DKP SL + D+ G+I +A LG LEY LEEG W D+ I ++ Sbjct: 196 TWSLIDFDKPETSLWKKFDWWGLISMAVFLGSLEYVLEEGNNKDWFNDEHIVIGSVAMVI 255 Query: 507 AGVGFIWRSLAYDNPVVDLRALKDRNFALGCFFSFVTGIGIFATVYLTPVFLAHVRGFSA 566 V F WR+ D PVVD+RA DRNF++G FSFV GIG++ YL P++L VRG+ A Sbjct: 256 GAVVFFWRAFKVDFPVVDIRAFADRNFSIGSLFSFVMGIGLYGLTYLYPLYLGRVRGYDA 315 Query: 567 LDIGLAIFATGLFQICAIPFYTYLGRRVDLRWLMMFGMACFALSMWNFTPITHDWGWREL 626 L IG +F +GL P + ++D R +M G F W T +T DW + EL Sbjct: 316 LMIGETMFVSGLAMFFTAPIAGKVSTKLDPRVMMAIGFISFGCGTWIMTYVTTDWDFYEL 375 Query: 627 LLP 629 L+P Sbjct: 376 LIP 378 >BMEII1119 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 525 Score = 265 bits (678), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 134/303 (44%), Positives = 187/303 (61%), Gaps = 4/303 (1%) Query: 327 IVQRXGWLARVMSTRWLFSASAVGFTIASMLCGLAWDINSMIFFRALQGFLGGSMIPMVF 386 ++ G+L R++STR LF+ SA GFT+ASMLC A +I MI +RA+QGF+GG MIP VF Sbjct: 77 MIPLSGFLGRLLSTRVLFTISATGFTLASMLCATATNIEQMIVYRAIQGFIGGGMIPSVF 136 Query: 387 TSAFFYFSGHQRVIAAATVGALSSLAPTLGPTVGGWITSNYSWHWLFFINLAPGIFVAVV 446 +AF F +R I + +G L TL PT+GG+++ +SWHWLF +N+ PGI V + Sbjct: 137 AAAFTIFPPSKRSIVSPMIG----LVATLAPTIGGYLSHAFSWHWLFLVNVGPGILVTIA 192 Query: 447 VPMLVRIDKPNLSLLRGADYLGMILLAASLGCLEYSLEEGPRLGWMGDDIIRTTVWIAIV 506 L+ D+ +LSLL D+ G+ +AA LG LEY LEEGPR W+ D I I V Sbjct: 193 AWNLIDFDEGDLSLLDKFDWWGLFGMAAFLGSLEYVLEEGPRNDWLQDHTIFIMSIILTV 252 Query: 507 AGVGFIWRSLAYDNPVVDLRALKDRNFALGCFFSFVTGIGIFATVYLTPVFLAHVRGFSA 566 + F +R + P+VD RA ++ NFA G FSFV G+G++ YL P++L+ +RG+ A Sbjct: 253 GAIVFFYRVFTAEQPIVDFRAFRNMNFAFGSLFSFVMGVGLYGLTYLYPLYLSMIRGYDA 312 Query: 567 LDIGLAIFATGLFQICAIPFYTYLGRRVDLRWLMMFGMACFALSMWNFTPITHDWGWREL 626 L IG A+F +GL P +L R+D R +MM G FA+ W T +T DW + EL Sbjct: 313 LMIGEALFVSGLAMFFTAPVAGFLSNRMDPRLMMMIGFVGFAIGTWLVTGLTADWDFNEL 372 Query: 627 LLP 629 L+P Sbjct: 373 LMP 375 >mll2590 [V] COG1566 Multidrug resistance efflux pump Mlo Mesorhizobium loti Length = 367 Score = 263 bits (672), Expect = 9e-70, Method: Compositional matrix adjust. Identities = 146/314 (46%), Positives = 210/314 (66%), Gaps = 1/314 (0%) Query: 18 APKGKKRFIKFAVPALVLLAVAA-YLVYWFAEGRHWEHTDDAYVGGDITVIAPKVPGNIV 76 AP +R + A + + VA Y W+ GR TDDAYVGG++T +AP+V G+I Sbjct: 22 APAKSRRKPIVMLGAAIAIGVAGWYGFQWWQAGRFVMSTDDAYVGGNVTPLAPRVAGHID 81 Query: 77 KVLVADNQRVKAGDLLVKIDDRDYVAVLNKLDAAVQAQQAALANIDAERRLQEAVIEQGK 136 ++LV DNQ V AG L+++IDDR + A + + A+VQ QQ+AL N+ A+ LQ ++IEQ + Sbjct: 82 QILVEDNQHVDAGQLIIRIDDRPFKAAVERARASVQQQQSALDNLRAQVSLQNSLIEQAE 141 Query: 137 AGVAASNADLTRTRDDQTRYQSLSSRAAVSVQSFQKADADYKQAQANGQKAQAGLLAAQR 196 A + A +A T T D RY+ L+S A S Q Q++ A QA+A+ ++AGL AA++ Sbjct: 142 ADLEAKSAAATFTTQDAKRYEVLASTRAGSQQDAQRSLAADGQAKASVSASRAGLAAARQ 201 Query: 197 QLDVLATQKQKVQAAMQQAIAERNLAQLNVGYTELRAPVDGVVGNRRARTGAYAATGAQL 256 QLDVL TQ + AA+ A A+ + A+L++G+T++RAP+DG+VGNR A+ G Y + G+ L Sbjct: 202 QLDVLNTQISEATAAVLAAKADLDTAELDLGFTQIRAPIDGLVGNRLAQVGTYVSPGSYL 261 Query: 257 LSVVPAEGLWVDANFKESQIAHFQSGMTVKIKADVLPGETFQGHVASIAPATGAQFSILP 316 L++VP GLWVDANFKE Q+ G + D+ P + +GHV+S+ PATGA FS++P Sbjct: 262 LTIVPQSGLWVDANFKEDQLRRMADGQAATVYTDIAPDQPLKGHVSSLGPATGAIFSVIP 321 Query: 317 AENATGNFTKIVQR 330 A+NATGNFTKIVQR Sbjct: 322 AQNATGNFTKIVQR 335 >mlr4819 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 531 Score = 261 bits (668), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 136/303 (44%), Positives = 190/303 (62%) Query: 327 IVQRXGWLARVMSTRWLFSASAVGFTIASMLCGLAWDINSMIFFRALQGFLGGSMIPMVF 386 ++ G+L+R++STR LF+ +A GFT AS L A +I+ MI +RA+QGF+GG MIP VF Sbjct: 78 MIPLSGFLSRMLSTRVLFTIAAAGFTAASALAATATNIDQMIVYRAVQGFIGGGMIPSVF 137 Query: 387 TSAFFYFSGHQRVIAAATVGALSSLAPTLGPTVGGWITSNYSWHWLFFINLAPGIFVAVV 446 +AF F +R + + +G +++LAPT+GPTVGG+I+ +SWHWLF +N+ PGI VA Sbjct: 138 AAAFTIFPPSKRAVVSPMIGLVATLAPTIGPTVGGYISHAFSWHWLFLVNVVPGILVATA 197 Query: 447 VPMLVRIDKPNLSLLRGADYLGMILLAASLGCLEYSLEEGPRLGWMGDDIIRTTVWIAIV 506 L+ DKPNL L D+ G+ +AA LGC+EY LEEGP W+ D + + + Sbjct: 198 AWSLIDFDKPNLKLFNKFDWWGLAGMAAFLGCMEYVLEEGPNNDWLQDQGVFICAIVMTI 257 Query: 507 AGVGFIWRSLAYDNPVVDLRALKDRNFALGCFFSFVTGIGIFATVYLTPVFLAHVRGFSA 566 V F WR + P+VDLRA + NFA G FSFV GIG++ YL PVFL +RG+ + Sbjct: 258 GAVIFFWRVFTAEEPIVDLRAFSNVNFAFGSLFSFVIGIGLYGLTYLYPVFLGRIRGYDS 317 Query: 567 LDIGLAIFATGLFQICAIPFYTYLGRRVDLRWLMMFGMACFALSMWNFTPITHDWGWREL 626 + IG A+F +GL P +L ++DLR +MM G FA W T +T DW + EL Sbjct: 318 MMIGEALFVSGLAMFVTAPISGFLSSKIDLRLMMMIGFFGFATGTWWMTHLTADWDFYEL 377 Query: 627 LLP 629 L+P Sbjct: 378 LIP 380