BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0155.p (480 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC1411 [GEPR] COG0477 Permeases of the major facilitator superfa... 655 0.0 RSc1852 [GEPR] COG0477 Permeases of the major facilitator superf... 627 e-179 RSc1292 [GEPR] COG0477 Permeases of the major facilitator superf... 422 e-118 YPO3268 [GEPR] COG0477 Permeases of the major facilitator superf... 400 e-111 emrB [GEPR] COG0477 Permeases of the major facilitator superfami... 383 e-106 >VC1411 [GEPR] COG0477 Permeases of the major facilitator superfamily Vch Vibrio cholerae Length = 511 Score = 655 bits (1689), Expect = 0.0, Method: Compositional matrix adjust. Identities = 311/480 (64%), Positives = 382/480 (79%) Query: 1 VLDTTIANVSVSTISGALGASSSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFITSM 60 +LDTTIANVSVS I+G+LG S+SQGTYVITSYAVAEAI+VPLTGWLA+RFG++RVF+T Sbjct: 32 ILDTTIANVSVSNIAGSLGTSTSQGTYVITSYAVAEAISVPLTGWLASRFGSIRVFVTCF 91 Query: 61 ILFGVFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAAAAVGLWAMT 120 +LFGVFS LCG+ANS+ L+ FRVL G GGPLMPLSQTL++RIFPK K+ AA+G+W+MT Sbjct: 92 LLFGVFSLLCGLANSMSTLVMFRVLLGFVGGPLMPLSQTLMIRIFPKNKSHAAIGIWSMT 151 Query: 121 TLIAPIAGPILGGVLCDQYSWPYIFFINVPVALICGYMGWKMLKRYESPLLKLPIDKVGL 180 TL+API GPILGGVLCDQ SWPYIFFI +P A+ + WK+LK++E+ IDKVGL Sbjct: 152 TLVAPIMGPILGGVLCDQLSWPYIFFIKMPFAIAAALLCWKLLKKFETKTTHSKIDKVGL 211 Query: 181 ILMVIWVAALQLMLDEGKEKDWFASTEIVVLALIAAAGFIAFLIWELTERNPIVDLRVFR 240 L+V+WVAALQLMLDEGK+ DWF S+ IV LA+IA GFIAFLIWELTERNP+VDL+VFR Sbjct: 212 ALLVVWVAALQLMLDEGKDHDWFESSRIVFLAVIAVIGFIAFLIWELTERNPVVDLKVFR 271 Query: 241 HRGYTASVTTICLAFGAFFGATVLTPLWLQGYMGYTATHSGETTALTGILAVLTAPFVAK 300 HRGY+ S+ T+ LAFGAFF +V+TPLWLQ YMGYTAT SG TA GILAV AP VA Sbjct: 272 HRGYSISMVTLSLAFGAFFSISVVTPLWLQIYMGYTATISGHATASMGILAVFLAPIVAN 331 Query: 301 LSTRVDPRKLVFIGVMWLGAVTLFRSFNTTDMSNFQIGWPLLMLGIGLPLFFVPLTGLAL 360 LS++ DPR VF GVMWLG T R FNT DM+ QI WPL GIG+PLFFVPLT +AL Sbjct: 332 LSSKFDPRPFVFAGVMWLGLWTFMRGFNTVDMTFSQISWPLFFQGIGMPLFFVPLTAIAL 391 Query: 361 SSVEESETASAAGLMSFCRTMSGAIATSLVNTSWENKSIYYHAELAGMVDQFGDVSNTLA 420 SV+ E SAAGLM+F RT+SGA ATS++NTSWE+++ Y HAELAG+ D+ G + + Sbjct: 392 GSVKPHEMESAAGLMNFIRTLSGAFATSMINTSWEHETRYVHAELAGLTDKAGVATQAMQ 451 Query: 421 QAGMSLDQARANMEQMLQSQSIMLSTNHIFMMAAISFGLAAAAVWFAPKPKRVADTSAAH 480 +GMS +Q R+ M+ +LQ+QS+M++TN +F++ A+ F AA +WFAPKPK+ DTSA H Sbjct: 452 NSGMSAEQTRSAMDWILQNQSVMVATNQLFIVIALIFVFAACMIWFAPKPKQAVDTSAVH 511 >RSc1852 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 512 Score = 627 bits (1616), Expect = e-179, Method: Compositional matrix adjust. Identities = 305/481 (63%), Positives = 381/481 (79%), Gaps = 1/481 (0%) Query: 1 VLDTTIANVSVSTISGALGASSSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFITSM 60 VLD TIANVSV ISG LG S+SQGT+VITSYAVAEAI VPLTGWLA+RFGTVRVF +M Sbjct: 32 VLDMTIANVSVPNISGNLGVSTSQGTWVITSYAVAEAILVPLTGWLASRFGTVRVFAVAM 91 Query: 61 ILFGVFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAAAAVGLWAMT 120 FG+FSALCG+A SLGML+A R+ QGLAGGPLMPLSQTLLLRIFPKEKA AA+GLW+MT Sbjct: 92 GCFGLFSALCGLALSLGMLVAARICQGLAGGPLMPLSQTLLLRIFPKEKAGAAIGLWSMT 151 Query: 121 TLIAPIAGPILGGVLCDQYSWPYIFFINVPVALICGYMGWKMLKRYESPLLKLPIDKVGL 180 T++AP+ GPILGG LCD+YSWP+IF+IN+P+A+ C + WKML RYESP+ + PIDKVGL Sbjct: 152 TIVAPVLGPILGGYLCDEYSWPWIFYINLPIAVGCAWAAWKMLARYESPIARNPIDKVGL 211 Query: 181 ILMVIWVAALQLMLDEGKEKDWFASTEIVVLALIAAAGFIAFLIWELTERNPIVDLRVFR 240 L+V+WV +LQ+MLDEGK+ DWFAS+ I LA++AA GF AFLIWEL +P V+LRVFR Sbjct: 212 ALLVLWVGSLQIMLDEGKQLDWFASSTIAGLAVVAAIGFAAFLIWELHAEHPAVNLRVFR 271 Query: 241 HRGYTASVTTICLAFGAFFGATVLTPLWLQGYMGYTATHSGETTALTGILAVLTAPFVAK 300 HRG++ASV TI LAFGAFFGA VLTP WLQ +MGYTA +G+TTA +G A+ AP A Sbjct: 272 HRGFSASVLTISLAFGAFFGANVLTPQWLQSFMGYTALEAGKTTAWSGFFALFAAPIAAG 331 Query: 301 LSTRVDPRKLVFIGVMWLGAVTLFRSFNTTDMSNFQIGWPLLMLGIGLPLFFVPLTGLAL 360 L +VD RKLVF GV+WLG +TL+R+ TTDM+ +Q+ PL+ +G+G+P FFVP TGLA+ Sbjct: 332 LGGKVDARKLVFGGVIWLGIITLWRTVATTDMTYWQVAVPLMAMGLGIPFFFVPTTGLAM 391 Query: 361 SSVEESETASAAGLMSFCRTMSGAIATSLVNTSWENKSIYYHAELAGMVDQFGDVSNTLA 420 +SV+E E ASAAGLM+F RT+SGA ATSL+ T W++++ +HAEL G+ D G V L Sbjct: 392 ASVDEEEMASAAGLMNFLRTLSGAFATSLITTLWDDRATLHHAELVGVSDGDGSVRTMLE 451 Query: 421 QAGMSLDQARANMEQMLQSQSIMLSTNHIFMMAAISFGLAAAAVWFAPKPKR-VADTSAA 479 AG +LD +++Q+L SQS+ML+TN I ++F LAA+A+W APKP+R VA + Sbjct: 452 GAGSTLDAINQSIDQLLTSQSVMLATNDIMAWVGVAFVLAASAIWLAPKPRRTVAPGTGG 511 Query: 480 H 480 H Sbjct: 512 H 512 >RSc1292 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 518 Score = 422 bits (1085), Expect = e-118, Method: Compositional matrix adjust. Identities = 214/476 (44%), Positives = 305/476 (64%), Gaps = 5/476 (1%) Query: 1 VLDTTIANVSVSTISGALGASSSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFITSM 60 VLD++IANVS+ ISG LG + +QGT+VITS+AVA AI+VPLTGWL RFG VR+F+TS+ Sbjct: 32 VLDSSIANVSIPAISGDLGVAPNQGTWVITSFAVANAISVPLTGWLTQRFGQVRLFVTSI 91 Query: 61 ILFGVFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAAAAVGLWAMT 120 +LF + S CG+A ++G LIA R+LQG GP++PLSQ+LLL +P K++ A+ LW MT Sbjct: 92 LLFVLSSWACGLAPNMGTLIAARILQGAVAGPMIPLSQSLLLSTYPPAKSSMALALWGMT 151 Query: 121 TLIAPIAGPILGGVLCDQYSWPYIFFINVPVALICGYMGWKMLKRYESPLLKLPIDKVGL 180 TL+API GPI GG + D +WP+IF+IN+PV ++ Y W + K ESP LPID++GL Sbjct: 152 TLVAPIMGPIFGGWISDNMTWPWIFYINIPVGILAAYATWVIYKDRESPTRALPIDRIGL 211 Query: 181 ILMVIWVAALQLMLDEGKEKDWFASTEIVVLALIAAAGFIAFLIWELTERNPIVDLRVFR 240 L+VIWV +LQLMLD GKE DWF S EIV L ++A GF FL+WELTE +P+VDL +F+ Sbjct: 212 ALLVIWVGSLQLMLDRGKELDWFNSAEIVTLTVVAVVGFAFFLVWELTEDHPVVDLTLFK 271 Query: 241 HRGYTASVTTICLAFGAFFGATVLTPLWLQGYMGYTATHSGETTALTGILAVLTAPFVAK 300 R ++A V I +A+G FFG V+ PLWLQ +GYTAT +G A GI A+L +P + K Sbjct: 272 GRNFSAGVVAISVAYGLFFGNLVILPLWLQTIVGYTATDAGLVMAPVGIFAILLSPVIGK 331 Query: 301 LSTRVDPRKLVFIGVMWLGAVTLFRSFNTTDMSNFQIGWPLLMLGIGLPLFFVPLTGLAL 360 ++D R + + V RS T + + + P L+ G + +FF+PLT + L Sbjct: 332 NLPKMDARWVATTAFITFALVFWMRSRFTIQVDTWTLMVPTLIQGAAMAMFFIPLTSIIL 391 Query: 361 SSVEESETASAAGLMSFCRTMSGAIATSLVNTSWENKSIYYHAELAGMVDQFGDVSNT-- 418 S + +A+GL +F R M G I S+ T W+N+S +HA+L + + + Sbjct: 392 SGLRPERIPAASGLSNFVRIMFGGIGASISTTVWDNRSALHHAQLVERANPYNPAYASSL 451 Query: 419 --LAQAGMSLDQARANMEQMLQSQSIMLSTNHIFMMAAISFGLAAAAVWFAPKPKR 472 Q GM QA +E+++ Q+ M+ N IF ++A+ F + A +W +P + Sbjct: 452 GDYTQMGMPSLQANGAIERIISQQAAMMGANDIFWISAVLFIVLIALIWLT-RPAK 506 >YPO3268 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 511 Score = 400 bits (1028), Expect = e-111, Method: Compositional matrix adjust. Identities = 208/475 (43%), Positives = 302/475 (63%), Gaps = 5/475 (1%) Query: 1 VLDTTIANVSVSTISGALGASSSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFITSM 60 VLD+TIANV++ TI+G LG+S+SQGT+VITS+ VA AI++P+TGWLA R G VR+F+ S Sbjct: 26 VLDSTIANVAIPTIAGDLGSSNSQGTWVITSFGVANAISIPVTGWLAKRVGEVRLFLWST 85 Query: 61 ILFGVFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAAAAVGLWAMT 120 LF + S LCGM+NSLGMLI FRV+QGL GPL+PLSQ+LLL +P K + A+ LW+MT Sbjct: 86 GLFVLASWLCGMSNSLGMLIFFRVIQGLVAGPLIPLSQSLLLNNYPPAKRSMALALWSMT 145 Query: 121 TLIAPIAGPILGGVLCDQYSWPYIFFINVPVALICGYMGWKMLKRYESPLLKLPIDKVGL 180 ++API GPILGG + D Y W +IFFIN+P+ L+ + LK E+ PID +GL Sbjct: 146 IVVAPIFGPILGGYISDNYHWGWIFFINIPIGLVVVLLAGSTLKGRETKTEIRPIDTIGL 205 Query: 181 ILMVIWVAALQLMLDEGKEKDWFASTEIVVLALIAAAGFIAFLIWELTERNPIVDLRVFR 240 +L+V+ + ALQ+MLD+GKE DWF STEI+VL ++A ++WELT+ +P++DL +F+ Sbjct: 206 VLLVVGIGALQIMLDQGKELDWFNSTEIIVLTVVAVVAITFLIVWELTDDHPVIDLSLFK 265 Query: 241 HRGYTASVTTICLAFGAFFGATVLTPLWLQGYMGYTATHSGETTALTGILAVLTAPFVAK 300 R +T + LA+ +FGA VL P LQ GYTAT +G +A GIL VL +P + + Sbjct: 266 SRNFTIGCLCLSLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGILPVLLSPLIGR 325 Query: 301 LSTRVDPRKLVFIGVMWLGAVTLFRSFNTTDMSNF-QIGWPLLMLGIGLPLFFVPLTGLA 359 + R+D R+LV + +R++ +F WP G + FF+PLT + Sbjct: 326 FAHRIDMRQLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFFQGFAIACFFMPLTTIT 385 Query: 360 LSSVEESETASAAGLMSFCRTMSGAIATSLVNTSWENKSIYYHAELAGMVDQFG----DV 415 LS + A+A+ L +F RT++G+I TS+ T W + +HA+L V+ + Sbjct: 386 LSGLPPERMAAASSLSNFMRTLAGSIGTSITTTLWTQRESLHHAQLTEFVNPYNPNATQA 445 Query: 416 SNTLAQAGMSLDQARANMEQMLQSQSIMLSTNHIFMMAAISFGLAAAAVWFAPKP 470 L + GMS QA A + + + +Q +++S N IF ++A F + A +WFA P Sbjct: 446 YQELEKLGMSQQQASAYLAREITNQGLIISANEIFWLSAGVFLMLLALIWFARPP 500 >emrB [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 512 Score = 383 bits (984), Expect = e-106, Method: Compositional matrix adjust. Identities = 204/475 (42%), Positives = 298/475 (62%), Gaps = 5/475 (1%) Query: 1 VLDTTIANVSVSTISGALGASSSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFITSM 60 VLD+TIANV++ TI+G LG+S SQGT+VITS+ VA AI++PLTGWLA R G V++F+ S Sbjct: 27 VLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAISIPLTGWLAKRVGEVKLFLWST 86 Query: 61 ILFGVFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAAAAVGLWAMT 120 I F + S CG+++SL MLI FRV+QG+ GPL+PLSQ+LLL +P K + A+ LW+MT Sbjct: 87 IAFAIASWACGVSSSLNMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAKRSIALALWSMT 146 Query: 121 TLIAPIAGPILGGVLCDQYSWPYIFFINVPVALICGYMGWKMLKRYESPLLKLPIDKVGL 180 ++API GPILGG + D Y W +IFFINVP+ + M + L+ E+ + ID VGL Sbjct: 147 VIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETRTERRRIDAVGL 206 Query: 181 ILMVIWVAALQLMLDEGKEKDWFASTEIVVLALIAAAGFIAFLIWELTERNPIVDLRVFR 240 L+VI + +LQ+MLD GKE DWF+S EI++L ++A ++WELT+ NPIVDL +F+ Sbjct: 207 ALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTDDNPIVDLSLFK 266 Query: 241 HRGYTASVTTICLAFGAFFGATVLTPLWLQGYMGYTATHSGETTALTGILAVLTAPFVAK 300 R +T I LA+ +FGA VL P LQ GYTAT +G +A GI+ V+ +P + + Sbjct: 267 SRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGIIPVILSPIIGR 326 Query: 301 LSTRVDPRKLVFIGVMWLGAVTLFRSFNTTDMSNFQI-GWPLLMLGIGLPLFFVPLTGLA 359 + ++D R+LV + +R++ +F WP + G + FF+PLT + Sbjct: 327 FAHKLDMRRLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGFAVACFFMPLTTIT 386 Query: 360 LSSVEESETASAAGLMSFCRTMSGAIATSLVNTSWENKSIYYHAELAGMVDQFGD----V 415 LS + A+A+ L +F RT++G+I TS+ T W N+ +HA+L V+ F + Sbjct: 387 LSGLPPERLAAASSLSNFTRTLAGSIGTSITTTMWTNRESMHHAQLTESVNPFNPNAQAM 446 Query: 416 SNTLAQAGMSLDQARANMEQMLQSQSIMLSTNHIFMMAAISFGLAAAAVWFAPKP 470 + L GM+ QA + Q + +Q +++S N IF M+A F + VWFA P Sbjct: 447 YSQLEGLGMTQQQASGWIAQQITNQGLIISANEIFWMSAGIFLVLLGLVWFAKPP 501