BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0004.0154.p         (97 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc1293 [V] COG1566 Multidrug resistance efflux pump Rso Ralston...   115   2e-26
VC1410 [V] COG1566 Multidrug resistance efflux pump Vch Vibrio c...   112   1e-25
RSc1853 [V] COG1566 Multidrug resistance efflux pump Rso Ralston...   112   2e-25
PA5159 [V] COG1566 Multidrug resistance efflux pump Pae Pseudomo...   108   2e-24
ZemrA [V] COG1566 Multidrug resistance efflux pump EcZ Escherich...   107   1e-23

>RSc1293 [V] COG1566 Multidrug resistance efflux pump Rso Ralstonia
           solanacearum
          Length = 428

 Score =  115 bits (289), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 51/85 (60%), Positives = 66/85 (77%)

Query: 1   MKADIYGSAIEYHGTVVGVAGGTGSAFAVIPAQNATGNWIKVVQRLPVRISIDRKELAEK 60
           + AD+YGS++ YHG VVG + GTGSAF+++PAQNATGNWIKVVQRLPVR+S+D KEL + 
Sbjct: 285 LVADVYGSSVTYHGKVVGFSAGTGSAFSLLPAQNATGNWIKVVQRLPVRVSLDPKELKDH 344

Query: 61  PLSVGLSMDVSIDTRGKSGSGSENT 85
           PL VGLSM+  +D   + G    +T
Sbjct: 345 PLRVGLSMEARVDIHDEGGQSLAST 369


>VC1410 [V] COG1566 Multidrug resistance efflux pump Vch Vibrio cholerae
          Length = 406

 Score =  112 bits (281), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 54/93 (58%), Positives = 67/93 (72%), Gaps = 3/93 (3%)

Query: 1   MKADIYGSAIEYHGTVVGVAGGTGSAFAVIPAQNATGNWIKVVQRLPVRISIDRKELAEK 60
           + AD+YG  + YHG V G +GGTGSAF++IPAQNATGNWIKVVQRLP+RI +D K+L   
Sbjct: 312 LTADLYGDDVTYHGVVAGFSGGTGSAFSMIPAQNATGNWIKVVQRLPIRIELDPKDLQAY 371

Query: 61  PLSVGLSMDVSIDTRGKSGSGSENTAMNSSAAK 93
           PL VGLSM  +IDT   +G+    T +   AAK
Sbjct: 372 PLQVGLSMVATIDT---AGTTDPQTLVQYRAAK 401


>RSc1853 [V] COG1566 Multidrug resistance efflux pump Rso Ralstonia
           solanacearum
          Length = 385

 Score =  112 bits (281), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 56/85 (65%), Positives = 65/85 (76%), Gaps = 3/85 (3%)

Query: 1   MKADIYGSAIEYHGTVVGVAGGTGSAFAVIPAQNATGNWIKVVQRLPVRISIDRKELAEK 60
           +KADIYG +  Y G V G +GG+G+AFA IPAQNATGNWIKVVQRLPVRI +D  EL + 
Sbjct: 300 VKADIYGGSASYRGVVEGFSGGSGAAFAAIPAQNATGNWIKVVQRLPVRIKLDAAELEKH 359

Query: 61  PLSVGLSMDVSIDTRGKSGSGSENT 85
           PL VGLSM V+IDT   S SGS+ T
Sbjct: 360 PLKVGLSMVVTIDT---SASGSQAT 381


>PA5159 [V] COG1566 Multidrug resistance efflux pump Pae Pseudomonas
           aeruginosa
          Length = 394

 Score =  108 bits (271), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 47/79 (59%), Positives = 63/79 (79%)

Query: 1   MKADIYGSAIEYHGTVVGVAGGTGSAFAVIPAQNATGNWIKVVQRLPVRISIDRKELAEK 60
           +++D+YGS + Y GTV  +  GTGSAF+++PAQNATGNWIK+VQR+PVRI ID +EL + 
Sbjct: 269 IRSDLYGSDVRYSGTVDSLGVGTGSAFSLLPAQNATGNWIKIVQRVPVRIHIDPQELQKH 328

Query: 61  PLSVGLSMDVSIDTRGKSG 79
           PL +GLSMDV +D   +SG
Sbjct: 329 PLRIGLSMDVKVDLHDQSG 347


>ZemrA [V] COG1566 Multidrug resistance efflux pump EcZ Escherichia coli
           O157:H7 EDL933
          Length = 390

 Score =  107 bits (266), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 50/91 (54%), Positives = 66/91 (72%)

Query: 4   DIYGSAIEYHGTVVGVAGGTGSAFAVIPAQNATGNWIKVVQRLPVRISIDRKELAEKPLS 63
           DIYG  ++Y G VVG+  GTGSAF+++PAQNATGNWIKVVQRLPVRI +D+K+L + PL 
Sbjct: 277 DIYGDDVKYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLPVRIELDQKQLEQYPLR 336

Query: 64  VGLSMDVSIDTRGKSGSGSENTAMNSSAAKS 94
           +GLS  VS++T  + G    N   ++  A S
Sbjct: 337 IGLSTLVSVNTTNRDGQVLANKVRSTPVAVS 367