BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0145.p (576 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0536 [GEPR] COG0477 Permeases of the major facilitator superf... 382 e-106 PA4343 [GEPR] COG0477 Permeases of the major facilitator superfa... 275 2e-73 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 233 6e-61 RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 232 2e-60 STM0689 [GEPR] COG0477 Permeases of the major facilitator superf... 225 2e-58 >RSp0536 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 441 Score = 382 bits (982), Expect = e-106, Method: Compositional matrix adjust. Identities = 204/344 (59%), Positives = 256/344 (74%), Gaps = 2/344 (0%) Query: 226 DAGGRKAALSLTILLMAAGTTLIGIAPTYEQIGLFAPLIIVVARLLQGFSAGGEMGSATA 285 D GR+ AL+L+ LLMA GT LI IAPTY Q G+ AP+I V+ARLLQGFSAGGEMG ATA Sbjct: 86 DRRGRRPALALSALLMALGTALIAIAPTYAQAGIAAPVIAVIARLLQGFSAGGEMGGATA 145 Query: 286 FLTEYAPVRERAFYSSWIQASIGVAVLLGAAVGSYVTSSLSPEALASWGWRLPFLLGIII 345 +L E AP +RAFY+SWIQAS+G+A++ GA +G+ TS L EAL +WGWR+PF LG++I Sbjct: 146 YLNEIAPPGKRAFYTSWIQASVGLAIVCGAMLGTLATSLLDAEALRAWGWRIPFALGVLI 205 Query: 346 GPVGYYIRHHLDETPAFLEA--KDKTDSPLKEIIRNYPRETTASFSMVILWTVCTYVLLF 403 GP+GY IR LDETPAF A + + DSPL E++R + R S+VILWTVCTYVLLF Sbjct: 206 GPIGYVIRSRLDETPAFARAATEARADSPLLEVVRRHRRAVLIGASIVILWTVCTYVLLF 265 Query: 404 YMPTYSIKVLKLPQSTGFIAGMVGGLCIMVFAPVVGRIADRYGRRGLLSGAALLILLLAY 463 YM TY+I VLKLP S GF M G+ +M+ AP+ G +ADR G + +LSGAAL IL+LAY Sbjct: 266 YMQTYAIHVLKLPSSAGFAGSMASGVTMMLTAPLFGWLADRLGYQRVLSGAALAILVLAY 325 Query: 464 PMFAYINHAPGLGSLLVFQLVFGILIATYTGPILAAFSELFPAKVLSTGLSVAYNLAVTI 523 P++AY+NHAP G+L+ Q+VFG+L A YTGPI AF++LFP KVLSTGLS AYNL V + Sbjct: 326 PLYAYLNHAPAAGTLIGVQIVFGLLSAAYTGPIPVAFADLFPTKVLSTGLSTAYNLTVML 385 Query: 524 FGGFASFIITGLIAATGSTMAPAFYVMIAAAISLVGTRFVREPA 567 GGFA F +T L A +AP YVM+AA +SL+GT ++R A Sbjct: 386 IGGFAPFYLTWLSHAFDPMLAPVLYVMVAALVSLIGTLWLRAAA 429 >PA4343 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 439 Score = 275 bits (704), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 164/344 (47%), Positives = 215/344 (62%), Gaps = 2/344 (0%) Query: 226 DAGGRKAALSLTILLMAAGTTLIGIAPTYEQIGLFAPLIIVVARLLQGFSAGGEMGSATA 285 D GRKAA+ L ILLM +I APTY IG+ APL+IV+AR+LQGF+ GGE SATA Sbjct: 78 DRRGRKAAMQLIILLMTLSIAMIAFAPTYAAIGVGAPLLIVIARMLQGFATGGEYASATA 137 Query: 286 FLTEYAPVRERAFYSSWIQASIGVAVLLGAAVGSYVTSSLSPEALASWGWRLPFLLGIII 345 FL E AP R Y SW +AV GA +G+ VT L EAL SWGWR+PFL G++I Sbjct: 138 FLVESAPPHRRGLYGSWQLFGQCLAVFAGAGMGALVTHCLDAEALESWGWRVPFLFGLLI 197 Query: 346 GPVGYYIRHHLDETPAFLEA--KDKTDSPLKEIIRNYPRETTASFSMVILWTVCTYVLLF 403 GPVG +IR ++ ET AFLEA + L ++R Y R S + ++ TV YV+L Sbjct: 198 GPVGLWIRRYMGETEAFLEAIREPGERQGLLGVLREYRRSVLVSMGLTVVGTVSFYVVLV 257 Query: 404 YMPTYSIKVLKLPQSTGFIAGMVGGLCIMVFAPVVGRIADRYGRRGLLSGAALLILLLAY 463 MPT++ K L LP F+ M + + P+ G ++DR GRR +L A L +L+ Y Sbjct: 258 NMPTFAHKQLGLPLDEVFMVQMAAVALMTLVIPLAGGLSDRVGRRPVLLVATLAFMLMVY 317 Query: 464 PMFAYINHAPGLGSLLVFQLVFGILIATYTGPILAAFSELFPAKVLSTGLSVAYNLAVTI 523 P+FA++ AP LG LL+ QL+ I + GP A +E FP +V STGL+VAYNLAV + Sbjct: 318 PLFAWVAAAPSLGRLLLMQLLLCTAIGGFFGPAPTAVAEQFPVRVRSTGLAVAYNLAVML 377 Query: 524 FGGFASFIITGLIAATGSTMAPAFYVMIAAAISLVGTRFVREPA 567 FGGFA FI+T L GS +APAFYV+ AA + L+ T ++RE A Sbjct: 378 FGGFAPFIVTWLTEVGGSPVAPAFYVLGAAFLGLLATLYLREGA 421 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 233 bits (595), Expect = 6e-61, Method: Compositional matrix adjust. Identities = 138/352 (39%), Positives = 198/352 (56%), Gaps = 3/352 (0%) Query: 217 GAXTLMADLDAGGRKAALSLTILLMAAGTTLIGIAPTYEQIGLFAPLIIVVARLLQGFSA 276 GA L A +D GR+A L LT++LMA GT LI + P Y IGL APL++++ RLLQGFSA Sbjct: 69 GAIVLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLIGRLLQGFSA 128 Query: 277 GGEMGSATAFLTEYAPVRERAFYSSWIQASIGVAVLLGAAVGSYVTSSLSPEALASWGWR 336 GGE G + +L+E A + FY SW S VAV+ A +G ++ LSP+ + WGWR Sbjct: 129 GGEPGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSPKEMGEWGWR 188 Query: 337 LPFLLGIIIGPVGYYIRHHLDETPAFLEAKDK--TDSPLKEIIRNYPRETTASFSMVILW 394 +PFL+G +I P ++IR L ET F + K + L+ + N+ R A + ++ Sbjct: 189 VPFLIGCLIVPFLFFIRRSLRETEEFEQRKHRPTMGELLRSMGENW-RLAGAGTLLAVMT 247 Query: 395 TVCTYVLLFYMPTYSIKVLKLPQSTGFIAGMVGGLCIMVFAPVVGRIADRYGRRGLLSGA 454 TV Y++ Y PT+ VL + I + G +++ PV+G ++DR GRR L Sbjct: 248 TVSFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMGSLSDRIGRRTPLIVF 307 Query: 455 ALLILLLAYPMFAYINHAPGLGSLLVFQLVFGILIATYTGPILAAFSELFPAKVLSTGLS 514 + L LL AYP ++ P G LL +L L Y G ++ +E+ P ++ +TG S Sbjct: 308 SALTLLTAYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIVTLTEIMPPQLRTTGFS 367 Query: 515 VAYNLAVTIFGGFASFIITGLIAATGSTMAPAFYVMIAAAISLVGTRFVREP 566 +AY+LA IFGGF I TGLI ATG+ P ++ AA LV T V +P Sbjct: 368 LAYSLATAIFGGFTPAIATGLIHATGNKAMPGLWLSFAAICGLVATLTVVKP 419 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 232 bits (591), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 143/355 (40%), Positives = 196/355 (55%), Gaps = 7/355 (1%) Query: 217 GAXTLMADLDAGGRKAALSLTILLMAAGTTLIGIAPTYEQIGLFAPLIIVVARLLQGFSA 276 GA L A +D GR+A L LT+ LMA GT LI + P Y IGL APL++++ RLLQGFSA Sbjct: 69 GALILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIGRLLQGFSA 128 Query: 277 GGEMGSATAFLTEYAPVRERAFYSSWIQASIGVAVLLGAAVGSYVTSSLSPEALASWGWR 336 G E+G + +L E + + F+ SW AS VAV+ A +G ++ LSP+ + WGWR Sbjct: 129 GVELGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPKEMGEWGWR 188 Query: 337 LPFLLGIIIGPVGYYIRHHLDETPAFLEAKDKTDSPLKEIIR----NYPRETTASFSMVI 392 +PFL+G +I P + IR L ET F + K + L EI R N+ R A +V+ Sbjct: 189 VPFLVGCLIVPFLFLIRRSLQETEEFKQRKHR--PALGEIFRSMGENW-RLVGAGTLLVV 245 Query: 393 LWTVCTYVLLFYMPTYSIKVLKLPQSTGFIAGMVGGLCIMVFAPVVGRIADRYGRRGLLS 452 + TV Y++ Y PT+ VL L I + G + PV+G ++DR GRR LL Sbjct: 246 MTTVSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIGRRPLLI 305 Query: 453 GAALLILLLAYPMFAYINHAPGLGSLLVFQLVFGILIATYTGPILAAFSELFPAKVLSTG 512 L LL AYP ++ P G LL +L L +Y G ++ +E+ P V +TG Sbjct: 306 TFTALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPPAVRTTG 365 Query: 513 LSVAYNLAVTIFGGFASFIITGLIAATGSTMAPAFYVMIAAAISLVGTRFVREPA 567 S+AY+LA IFGGF I T LI ATG+ P ++ AA LV T V +PA Sbjct: 366 FSLAYSLATAIFGGFTPAIATWLIHATGNKAMPGLWLSFAAICGLVATLIVVKPA 420 >STM0689 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 434 Score = 225 bits (574), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 131/352 (37%), Positives = 198/352 (56%), Gaps = 5/352 (1%) Query: 217 GAXTLMADLDAGGRKAALSLTILLMAAGTTLIGIAPTYEQIGLFAPLIIVVARLLQGFSA 276 GA L A +D GR+ L +T+ +M GT LI + P Y+ IGL AP ++++ RLLQGFSA Sbjct: 72 GAIVLGAYIDRIGRRKGLMVTLAIMGCGTLLIALVPGYQTIGLAAPALVLLGRLLQGFSA 131 Query: 277 GGEMGSATAFLTEYAPVRERAFYSSWIQASIGVAVLLGAAVGSYVTSSLSPEALASWGWR 336 G E+G + +L+E A + FY+SW AS VA+++ A +G + +L +A++ WGWR Sbjct: 132 GVELGGVSVYLSEIATPGNKGFYTSWQSASQQVAIVVAALIGYSLNITLGHDAISEWGWR 191 Query: 337 LPFLLGIIIGPVGYYIRHHLDETPAFLEAKDKTDSP--LKEIIRNYPRETTASFSMVILW 394 +PF +G +I P+ + +R L ET AFL+ K + D+ I +N+ R TA +V + Sbjct: 192 IPFFIGCMIIPLIFVLRRSLQETEAFLQRKHRPDTREIFATIAKNW-RIITAGTLLVAMT 250 Query: 395 TVCTYVLLFYMPTYSIKVLKLPQSTGFIAGMVGGLCIMVFAPVVGRIADRYGRRGLLSGA 454 T Y + Y PTY VL L I M+ G+ ++ P+ G I+DR GRR +L G Sbjct: 251 TTTFYFITVYTPTYGRTVLNLSARDSLIVTMLVGVSNFIWLPIGGAISDRIGRRAVLMGI 310 Query: 455 ALLILLLAYPMFAYINHAPGLGSLLVFQLVFGILIATYTGPILAAFSELFPAKVLSTGLS 514 LL L+ +P+ ++ AP + + L F Y G ++AA +E+ P V + G S Sbjct: 311 TLLALITTWPVMQWLTAAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVYVRTVGFS 370 Query: 515 VAYNLAVTIFGGFASFIITGLIAATGSTMAPAFYVMIAAAISLVGTR--FVR 564 +A++LA IFGG I T L+ TG +P +++M AA L T FVR Sbjct: 371 LAFSLATAIFGGLTPAISTALVKLTGDKSSPGWWLMCAALCGLAATAMLFVR 422