BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0004.0140.p         (162 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc0468 [LR] COG0494 NTP pyrophosphohydrolases including oxidati...   177   6e-45
NMB0642 [LR] COG0494 NTP pyrophosphohydrolases including oxidati...   142   3e-34
NMA0852 [LR] COG0494 NTP pyrophosphohydrolases including oxidati...   138   4e-33
YPO2054 [LR] COG0494 NTP pyrophosphohydrolases including oxidati...    96   2e-20
ntpA [LR] COG0494 NTP pyrophosphohydrolases including oxidative ...    85   5e-17

>RSc0468 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage
           repair enzymes Rso Ralstonia solanacearum
          Length = 162

 Score =  177 bits (450), Expect = 6e-45,   Method: Compositional matrix adjust.
 Identities = 97/156 (62%), Positives = 109/156 (69%), Gaps = 14/156 (8%)

Query: 4   PFKIPESVLVVIYTAALDVLLIERTDKAGYWQSVTGSKDTPDEPLMLTARREVGEETGIV 63
           P KIP SVLVVI+T  L VL++ER D  G+WQSVTGS DTPDE L  TARREV EETGI 
Sbjct: 7   PHKIPVSVLVVIHTPDLQVLVMERADHPGFWQSVTGSCDTPDELLAETARREVLEETGI- 65

Query: 64  ISDEISVSPTVPNRVPCDHLSDWKLSNDYEIYPVWRHRYAPGVTRNIEHVFGLLVPQGIP 123
                    T+ +R     L DW    +YEIYP WRHRYAPGVTRN EH FGLLV   +P
Sbjct: 66  --------DTMQHR-----LIDWGHHIEYEIYPRWRHRYAPGVTRNTEHWFGLLVGGEVP 112

Query: 124 VTLAPREHTRYQWLPYRAAADQCFSPSNAEAILQLP 159
           V L+PREH + +WLPYR AA +CFS SN EAILQLP
Sbjct: 113 VRLSPREHLQAEWLPYREAAARCFSRSNGEAILQLP 148


>NMB0642 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage
           repair enzymes Nme Neisseria meningitidis MC58
          Length = 152

 Score =  142 bits (358), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 76/162 (46%), Positives = 95/162 (58%), Gaps = 15/162 (9%)

Query: 1   MNRPFKIPESVLVVIYTAALDVLLIERTDKAGYWQSVTGSKDTPDEPLMLTARREVGEET 60
           M +P K P S LVV+Y+    +LLIERT   G+WQSVTGS + P E +  TARREV EET
Sbjct: 3   MAKPLKYPVSALVVLYSGDGGILLIERTHPEGFWQSVTGSLE-PGETVAQTARREVWEET 61

Query: 61  GIVISDEISVSPTVPNRVPCDHLSDWKLSNDYEIYPVWRHRYAPGVTRNIEHVFGLLVPQ 120
           GI+++D                L DW  S  YEIY  WRHRY  GV  N EH+F   +P+
Sbjct: 62  GILLAD--------------GQLQDWHDSTVYEIYHHWRHRYPKGVFENREHLFSAEIPR 107

Query: 121 GIPVTLAPREHTRYQWLPYRAAADQCFSPSNAEAILQLPRYI 162
             P+ L P EH  Y W     AA++ FSPSN  AIL+L R++
Sbjct: 108 DTPIALQPEEHVSYGWFDMEEAAEKVFSPSNRRAILELGRFL 149


>NMA0852 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage
           repair enzymes NmA Neisseria meningitidis Z2491
          Length = 152

 Score =  138 bits (348), Expect = 4e-33,   Method: Compositional matrix adjust.
 Identities = 75/162 (46%), Positives = 94/162 (58%), Gaps = 15/162 (9%)

Query: 1   MNRPFKIPESVLVVIYTAALDVLLIERTDKAGYWQSVTGSKDTPDEPLMLTARREVGEET 60
           M +P K P S LVV+Y+    +LLIERT   G+WQSVTGS + P E +  TARREV EET
Sbjct: 3   MAKPLKYPVSALVVLYSGDGGILLIERTHPKGFWQSVTGSLE-PGETVAQTARREVWEET 61

Query: 61  GIVISDEISVSPTVPNRVPCDHLSDWKLSNDYEIYPVWRHRYAPGVTRNIEHVFGLLVPQ 120
           GI+++D                L DW  S  YEIY  WRHRY  GV  N EH+F   +P+
Sbjct: 62  GILLAD--------------GQLQDWHDSTVYEIYHHWRHRYPKGVFENREHLFSAEIPR 107

Query: 121 GIPVTLAPREHTRYQWLPYRAAADQCFSPSNAEAILQLPRYI 162
             P+ L P EH  Y W     AA++ FS SN  AIL+L R++
Sbjct: 108 DTPIVLQPEEHVSYGWFDMEEAAEKVFSSSNRCAILELGRFL 149


>YPO2054 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage
           repair enzymes Ype Yersinia pestis
          Length = 147

 Score = 96.3 bits (238), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 65/152 (42%), Positives = 86/152 (56%), Gaps = 16/152 (10%)

Query: 5   FKIPESVLVVIYT-AALDVLLIERTDKAGYWQSVTGSKDTPDEPLMLTARREVGEETGIV 63
           +K PESVLVVIY  ++  VL+++R D   +WQSVTGS +  + PL  TA+REV EE GI 
Sbjct: 3   YKRPESVLVVIYAKSSGRVLMLQRRDDPDFWQSVTGSLEEGEAPLQ-TAQREVKEEVGID 61

Query: 64  ISDEISVSPTVPNRVPCDHLSDWKLSNDYEIYPVWRHRYAPGVTRNIEHVFGLLVPQGIP 123
           I  E  V            L D +   ++E++   R RYAPG+TRN EH F L +P+   
Sbjct: 62  ILGENLV------------LLDCQRCVEFELFAHLRRRYAPGITRNKEHWFCLALPEERD 109

Query: 124 VTLAPREHTRYQWLPYRAAADQCFSPSNAEAI 155
           + +   EH  YQWL    AA    S SN +AI
Sbjct: 110 IVIT--EHLAYQWLDAAEAAVLTKSWSNQQAI 139


>ntpA [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage
           repair enzymes Eco Escherichia coli K12
          Length = 150

 Score = 85.1 bits (209), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 61/159 (38%), Positives = 85/159 (53%), Gaps = 18/159 (11%)

Query: 2   NRPFKIPESVLVVIYTAALD-VLLIERTDKAGYWQSVTGSKDTPDEPLMLTARREVGEET 60
           ++ +K P S+LVVIY      VL+++R D   +WQSVTGS +   E     A REV EE 
Sbjct: 3   DKVYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVE-EGETAPQAAMREVKEEV 61

Query: 61  GI-VISDEISVSPTVPNRVPCDHLSDWKLSNDYEIYPVWRHRYAPGVTRNIEHVFGLLVP 119
            I V++++++             L D + + ++EI+   RHRYAPGVTRN E  F L +P
Sbjct: 62  TIDVVAEQLT-------------LIDCQRTVEFEIFSHLRHRYAPGVTRNTESWFCLALP 108

Query: 120 QGIPVTLAPREHTRYQWLPYRAAADQCFSPSNAEAILQL 158
               +     EH  Y+WL   AAA    S SN +AI Q 
Sbjct: 109 HERQIVFT--EHLAYKWLDAPAAAALTKSWSNRQAIEQF 145