BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0124.p (230 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0275 [T] COG0664 cAMP-binding proteins - catabolite gene activ... 82 1e-15 SMa1067 [T] COG0664 cAMP-binding proteins - catabolite gene acti... 79 1e-14 RSp0805 [T] COG0664 cAMP-binding proteins - catabolite gene acti... 73 4e-13 SMc02175 [T] COG0664 cAMP-binding proteins - catabolite gene act... 71 2e-12 slr0449 [T] COG0664 cAMP-binding proteins - catabolite gene acti... 66 7e-11 >PA0275 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Pae Pseudomonas aeruginosa Length = 228 Score = 81.6 bits (200), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 60/217 (27%), Positives = 96/217 (44%) Query: 11 LNKSRWPAELTEDQMERLRQNIFEKSFASGTIIYPRGTPADHWFGLIEGMIKVDTVSQDG 70 L RW L E L + G ++ RG + ++EG I++ VS++G Sbjct: 11 LQAGRWFQGLPEALQTHLLALAQPRQLPPGQRLFARGDAPCGLYCVVEGAIRISAVSENG 70 Query: 71 RSTTFAGVPGGAWFGEGAVLKNEPRPYSIVAIRDSKLAFVPKQTFEWLLSQSTSFSRFVI 130 + V WFGE A+ + R + A ++L VP+ LL + + R V Sbjct: 71 KEALLILVEAPHWFGEIALFDGQARTHDAYAEGHTQLLQVPQAALLELLRREPHYWRDVA 130 Query: 131 DQLNWRCGYYVALIENRRLREASARVAFCLSELFNPQLYPSTEQALPLSQEEIGRLSGLS 190 ++ + +E L A+ R+A L L + Q L L QE++ + LS Sbjct: 131 LLMSHKLRLAFIALEEMALLPAAQRLARRLLMLAEGYDNSRSRQVLHLPQEQLALMLSLS 190 Query: 191 RQNTNRALRELADMKLLSVEYGSVVILDLSRLREFAH 227 RQ TN+ L++L +L + YG + ILDL+ LR H Sbjct: 191 RQTTNQILKDLEAQGILQLSYGGIEILDLAGLRAATH 227 >SMa1067 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Sme Sinorhizobium meliloti Length = 248 Score = 78.6 bits (192), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 55/217 (25%), Positives = 97/217 (44%), Gaps = 7/217 (3%) Query: 11 LNKSRWPAELTEDQMERLRQNIFEKSFASGTIIYPRGTPADHWFGLIEGMIKVDTVSQDG 70 + + W A +TE L ++ + FA ++Y G +GL+ G + +++ D Sbjct: 31 MRRGPWLASMTEPFRTELLRHAHLQKFAPDQVVYRHGDAVGGMYGLVAGSLTINSAPPDA 90 Query: 71 RSTTFA-GVPGGAWFGEGAVLKNEPRPYSIVAIRDSKLAFVPKQTFEWLLSQSTSFSRFV 129 S G+PG AW GEG L +PR + A+ + + VP E ++++ SR + Sbjct: 91 ASRLIHLGMPG-AWTGEGPFLTGQPRRVELRALGGAWMMHVPLDALEQMMARDPGVSRAI 149 Query: 130 IDQLNWRCGYYVALIENRRLREASARVAFCLSELFNPQLYPSTEQALPLSQEEIGRLSGL 189 + + +I + + R R+A L P +PLSQ ++G ++ Sbjct: 150 AMNTVFTVDVLLRIIHDLQKRAVGRRIASVLQRASWVGDMP-----IPLSQTDLGIMANA 204 Query: 190 SRQNTNRALRELADMKLLSVEYGSVVILDLSRLREFA 226 SRQ N A++ A +S Y SV + + LR F+ Sbjct: 205 SRQQVNTAMQRFARAGWVSYTYRSVTVSNSQALRRFS 241 >RSp0805 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Rso Ralstonia solanacearum Length = 239 Score = 73.2 bits (178), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 57/219 (26%), Positives = 98/219 (44%), Gaps = 4/219 (1%) Query: 11 LNKSRWPAELTEDQMERLRQNIFEKSFASGTIIYPRGTPADHWFGLIEGMIKVDTVSQDG 70 L+ S W L + L + G +++ RG P+D + ++EG I++ S +G Sbjct: 20 LHASSWFGALGTPLQDALIGMAVVRRLGGGDMLFRRGDPSDGLYCVVEGAIRIGATSAEG 79 Query: 71 RSTTFAGVPGGAWFGEGAVLKNEPRPYSIVAIRDSKLAFVPKQTFEWLLSQSTSFSRFVI 130 R + A + WFGE VL + R + A + L +P+ LL + + R Sbjct: 80 RESLLAVLEPVNWFGEIGVLDRQARTHDARADDGALLLHMPQAPLVALLDSAPASLRAFA 139 Query: 131 DQLNWRCGYYVALIENRRLREASARVA---FCLSELFNPQLYPSTEQALPLSQEEIGRLS 187 L + ++E L + RVA +++ + L T + L + QE++ L Sbjct: 140 LLLTHKLRLTFTVLEETALLPTAERVARRLLLMADGYG-DLRLGTRRVLRVPQEQLALLL 198 Query: 188 GLSRQNTNRALRELADMKLLSVEYGSVVILDLSRLREFA 226 LSRQ N+ L++ LL + YG + +LD + LR A Sbjct: 199 ALSRQTVNQVLKDFEARGLLRLAYGEIELLDFAGLRALA 237 >SMc02175 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Sme Sinorhizobium meliloti Length = 234 Score = 70.9 bits (172), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 54/200 (27%), Positives = 92/200 (46%), Gaps = 5/200 (2%) Query: 35 KSFASGTIIYPRGTPADHWFGLIEGMIKVDTVSQDGRSTTFAGVPGGAWFGEGAVLKNEP 94 + +++GT+I+ RG D+ ++ G IK+ + GR GA FGE A+L +P Sbjct: 35 RKWSAGTVIFQRGDQGDYMIVVVSGRIKLSLFTPQGRELMLRQHEAGALFGEMALLDGQP 94 Query: 95 RPYSIVAIRDSKLAFVPKQTFEWLLSQSTSFSRFVIDQLNWRCGYYVALIENRRLREASA 154 R A+ ++ + K+ F L++Q + VI L + +E L + +A Sbjct: 95 RSADATAVTAAEGYVIGKKDFLALITQRPKTAEAVIRFLCAQLRDTTDRLETIALYDLNA 154 Query: 155 RVA----FCLSELFNPQLYPSTEQALPLSQEEIGRLSGLSRQNTNRALRELADMKLLSVE 210 RVA L ++ ++ S L LSQ +I + G SR NRA+ L + + Sbjct: 155 RVARFFLATLRQIHGSEMPQSANLRLTLSQTDIASILGASRPKVNRAILSLEESGAIKRA 214 Query: 211 YGSVVILDLSRLREFAHHEE 230 G ++ ++ RL A EE Sbjct: 215 DG-IICCNVGRLLSIADPEE 233 >slr0449 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Syn Synechocystis Length = 238 Score = 65.9 bits (159), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 51/230 (22%), Positives = 99/230 (43%), Gaps = 4/230 (1%) Query: 1 MPLSPELIAFLNKSRWPAELTEDQMERLRQNIFEKSFASGTIIYPRGTPADHWFGLIEGM 60 M ++P+L +L+K+ + +E + KS+ G +++ G +F + G Sbjct: 1 MTVAPDLALWLSKTLMFQNIDSHHLEMITAIAQVKSYGKGDVVFKEGDKPKGFFIVRSGR 60 Query: 61 IKVDTVSQDGRSTTFAGVPGGAWFGEGAVLKNEPRPYSIVAIRDSKLAFVPKQTFEWLLS 120 +K+ ++ G+ G F E AV N P P S + +++ F P+ F +L+ Sbjct: 61 VKIYKIAPGGKEQILRIFHRGEHFAEIAVFDNLPFPASAATLDQAEMIFFPRSPFLEMLA 120 Query: 121 QSTSFSRFVIDQLNWRCGYYVALIENRRLREASARVAFCLSELFNPQL----YPSTEQAL 176 Q + + ++ L+ + A+IE ++ R+A L L S L Sbjct: 121 QHPTLALNMLSSLSRHLRHLTAVIEELSFKDVPQRLASYLLRLGGVDTGTVEVLSLWVTL 180 Query: 177 PLSQEEIGRLSGLSRQNTNRALRELADMKLLSVEYGSVVILDLSRLREFA 226 L + ++ G +RA +L + L++V+ + +LD RLR A Sbjct: 181 DLPKSQLAAQLGTIPATLSRAFYQLKNEDLIAVKGAEIQLLDCDRLRALA 230