BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0076.p (282 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value DRA0336 [K] COG0583 Transcriptional regulator Dra Deinococcus ra... 120 2e-27 PA5029 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 120 4e-27 YPO1929 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 114 4e-25 VC1588 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae 111 2e-24 PA3594 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 110 3e-24 >DRA0336 [K] COG0583 Transcriptional regulator Dra Deinococcus radiodurans Length = 316 Score = 120 bits (302), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 77/234 (32%), Positives = 124/234 (52%), Gaps = 4/234 (1%) Query: 1 VAEAARKLNIVQPALSRQIHDLEEQLGTQLFQRSIRGTQLTVAGVQFMKDCSKLLIDLED 60 V AA +L I QP LS+QI +LE ++GT LF R RG +LT AG F++ + +E Sbjct: 34 VTRAAARLGIQQPPLSQQIRELEREIGTPLFHRVPRGVELTEAGHTFLRLVQSIPAQVEG 93 Query: 61 AKKRALRAASGKLGSLRIGISPNHTAHPELLKRLRRFREICPDVALMLEPALSPRQLLDV 120 A A RA G+ G LR+G + + +P++ LRR+R++ PDV L L + L ++ Sbjct: 94 ATHEARRAGRGETGELRVGFTGAASINPQVQGLLRRYRDLYPDVRLTLTEKNTVTLLDEL 153 Query: 121 KEERMDGGFIAFRDLADK--QLSGIKVLRSGLMLAVSSDHKYAEQPPDRLSEMKDEPCVW 178 + ++D + R L L+ V R ++ V H A+ P L ++DE + Sbjct: 154 RSHQLDA--VLARPLPQHLGDLTLTLVAREPMVAVVPRGHPAAQTRPLPLERLRDETFIT 211 Query: 179 FPRDRAPEYHDYLIQQCMAAGLTPKQILVGTDVGTTLGMVAAGMGYSIVSEASK 232 PR+ P +D + Q C AAG P+ + + + + +VAAG+G S+V +A + Sbjct: 212 TPREFGPLIYDTVWQACRAAGFEPRLGQLAPQMLSIVSLVAAGLGVSLVPDAMR 265 >PA5029 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 301 Score = 120 bits (300), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 86/275 (31%), Positives = 148/275 (53%), Gaps = 7/275 (2%) Query: 4 AARKLNIVQPALSRQIHDLEEQLGTQLFQRSIRGTQLTVAGVQFMKDCSKLLIDLEDAKK 63 AA +L I QP LS+QI LEE++G +LF+R+ R +LT AG F+ + ++L ++ A Sbjct: 21 AAERLGISQPPLSQQIQALEEEIGARLFERTNRRVELTDAGRLFLDESRQVLAQVDKAVL 80 Query: 64 RALRAASGKLGSLRIGISPNHTAHPELLKRLRRFREICPDVALMLEPALSPRQLLD-VKE 122 A RA G+LG L+IG + + + + FR+ PDV L L+ +S RQ+L + E Sbjct: 81 LARRAHLGELGELKIGFTSSAPFTSTIPSSIHAFRKAYPDVHLDLQ-EMSSRQVLKALLE 139 Query: 123 ERMDGGFIAFRDLADKQLSGIKVLRSGLMLAVSSDHKYAEQPPDRL--SEMKDEPCVWFP 180 E + G I L D + +++ R L+ + +DH A D L + + +EP V+FP Sbjct: 140 ESLQVGVIRPLALPDA-VHWVELFREPLVAVLRADHPLAAGSEDGLAIAALAEEPFVFFP 198 Query: 181 RDRAPEYHDYLIQQCMAAGLTPKQILVGTDVGTTLGMVAAGMGYSIVSEASKYNSPNGVV 240 R +D +I AG +P+ ++ T +G+V+AG+G SI+ + + +GVV Sbjct: 199 RSYGTGLYDQVIALTRQAGFSPRIAQEASEAMTIIGLVSAGLGVSILPASFRRTRVDGVV 258 Query: 241 LHQHADIPDIHDVEFIFLSEND-SPILRAFAEVMN 274 +D P+ ++ +N+ SP+ +F +++ Sbjct: 259 YRTLSD-PEATTAVWLVRRQNEGSPLALSFIDLVT 292 >YPO1929 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 292 Score = 114 bits (284), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 84/267 (31%), Positives = 131/267 (49%), Gaps = 2/267 (0%) Query: 4 AARKLNIVQPALSRQIHDLEEQLGTQLFQRSIRGTQLTVAGVQFMKDCSKLLIDLEDAKK 63 AA +L I QP LS+QI DLE +LG LF+R G +LT AG+ F+ ++ + E A + Sbjct: 21 AAARLGIGQPPLSQQIKDLERELGALLFRRVSYGAELTEAGIAFLDVVKEIPVMAERAAQ 80 Query: 64 RALRAASGKLGSLRIGISPNHTAHPELLKRLRRFREICPDVALMLEPALSPRQLLDVKEE 123 A RA G+LG LR+G + + + + +R FR PDV L LE + R + E Sbjct: 81 AAQRAVRGELGVLRVGFTASSAFNSVVPTAIRAFRRAYPDVRLQLEEDNTTRLADGLNEG 140 Query: 124 RMDGGFIAFRDLADKQLSGIKVL-RSGLMLAVSSDHKYAEQPPDRLSEMKDEPCVWFPRD 182 +D F+ A + +++L +M+ ++ +H A LS +DE + FPR+ Sbjct: 141 SLDVAFLR-PGFAGSERFHLRMLSEEPMMIVMAENHPAASYEEISLSAFRDETFLLFPRE 199 Query: 183 RAPEYHDYLIQQCMAAGLTPKQILVGTDVGTTLGMVAAGMGYSIVSEASKYNSPNGVVLH 242 +D +I+ C AG P + + + + +VAA MG SIV + GVV Sbjct: 200 IGLTLYDSVIESCRTAGFEPTIGQLAPQIASVINLVAAEMGVSIVPASMSQVKVIGVVYR 259 Query: 243 QHADIPDIHDVEFIFLSENDSPILRAF 269 AD + + + SP+LR F Sbjct: 260 HIADQTPTAKLALAYRRGDTSPVLRNF 286 >VC1588 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae Length = 293 Score = 111 bits (277), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 75/263 (28%), Positives = 130/263 (49%) Query: 4 AARKLNIVQPALSRQIHDLEEQLGTQLFQRSIRGTQLTVAGVQFMKDCSKLLIDLEDAKK 63 AA +L I QP LS+QI LEE+LG LF+R RG +LT AG F +D + +L +E AK Sbjct: 22 AAEQLGIAQPPLSQQIKKLEEELGVNLFKRLSRGVELTPAGELFYQDATSILQQVERAKD 81 Query: 64 RALRAASGKLGSLRIGISPNHTAHPELLKRLRRFREICPDVALMLEPALSPRQLLDVKEE 123 R + A G+ LR+G + + + +L+++R+ E PD+ L+ P ++E+ Sbjct: 82 RVRQRARGEHLELRLGFAASTASSSVVLEKVRQLHETIPDLQLIAVEHPMPELARMIQEK 141 Query: 124 RMDGGFIAFRDLADKQLSGIKVLRSGLMLAVSSDHKYAEQPPDRLSEMKDEPCVWFPRDR 183 ++D F+ A + L + + + + H AE +L ++ E + FPR+ Sbjct: 142 QLDIAFMRLPCYASEALRRKILFDDPFVAVIPAVHTLAEVEKIQLIQLNHENVLMFPREV 201 Query: 184 APEYHDYLIQQCMAAGLTPKQILVGTDVGTTLGMVAAGMGYSIVSEASKYNSPNGVVLHQ 243 P +D + AAG+ + + T + M AG G +IV + + + VV+ Sbjct: 202 GPALYDNIEAAFSAAGVNIARSYAAPQLRTAITMAQAGFGIAIVPLSLTDHLDHSVVVKT 261 Query: 244 HADIPDIHDVEFIFLSENDSPIL 266 D+P + V + + + P+L Sbjct: 262 IQDMPFVSQVAIVSDAGHHHPLL 284 >PA3594 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 295 Score = 110 bits (275), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 73/226 (32%), Positives = 118/226 (52%), Gaps = 2/226 (0%) Query: 4 AARKLNIVQPALSRQIHDLEEQLGTQLFQRSIRGTQLTVAGVQFMKDCSKLLIDLEDAKK 63 AA +L I QPALS I LEEQLGTQL R+ + +LT AG + + LL+ E K+ Sbjct: 21 AAARLFISQPALSFDIKKLEEQLGTQLLLRNNKSVKLTGAGQVLLVEARNLLLQAEKVKR 80 Query: 64 RALRAASGKLGSLRIGISPNHTAHPELLKRLRRFREICPDVALMLEPALSPRQLLDVKEE 123 +A G +G LR+G N + L + + RF P++ ++L S Q ++ Sbjct: 81 LTQLSAEGDVGQLRVGFV-NSMLYRGLPRAMSRFEREHPNMEVVLGEMNSAEQAQALQRG 139 Query: 124 RMDGGFIAFRDLADKQLSGIKVLRSGLMLAVSSDHKYAEQPPDRLSEMKDEPCVWFPRDR 183 ++D GF+ + L + +S ++ + + + H+ A Q L+E++DE + FPR Sbjct: 140 QIDLGFVHWGRLPAEIVSE-PLISDPFLCCLPAGHRLAGQARLDLAELRDEDFILFPRHV 198 Query: 184 APEYHDYLIQQCMAAGLTPKQILVGTDVGTTLGMVAAGMGYSIVSE 229 +P YHD +I +C+ AG +P+ T MV GMG +++ E Sbjct: 199 SPHYHDLIIARCVDAGFSPRIRHEARLWQTVAAMVGLGMGVALIPE 244