BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0070.p (452 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0177 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransf... 640 0.0 PA5552 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransfe... 539 e-153 VC2762 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransfe... 521 e-148 YPO4119 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransf... 516 e-146 HI0642 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransfe... 516 e-146 >RSc0177 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Rso Ralstonia solanacearum Length = 455 Score = 640 bits (1651), Expect = 0.0, Method: Compositional matrix adjust. Identities = 311/453 (68%), Positives = 370/453 (81%), Gaps = 1/453 (0%) Query: 1 MNIVILAAGMGKRMQSALPKVLHPIAGKPLLRHVVDTAKVLAPTKLCVVYGHGGDAVPSS 60 MNIVILAAG+GKRM+SALPKVLHP+AGKPLL HV++TA+ L+PT+L VV GHGGD V Sbjct: 1 MNIVILAAGLGKRMRSALPKVLHPLAGKPLLAHVIETARSLSPTRLVVVVGHGGDRVRDM 60 Query: 61 FADNTLSFALQEPQLGTGHAVAQALPFIDDNAPTLVLYGDVPLTTPATLQRLLAAAGEDK 120 ++FA Q+ QLGTGHAV QAL +DD PTLVLYGDVPLT TL L+ AAG+D Sbjct: 61 VGAPDVTFATQDQQLGTGHAVMQALDQLDDTVPTLVLYGDVPLTRAETLNALVGAAGQDH 120 Query: 121 LAVLTITVADPTGYGRIVRE-DGKITRIVEQKDASEAERAISEINTGIIAAPTARLRAWL 179 L VLT+ + DPTGYGRIVR+ G+ITRIVEQKDA+E + AI E+NTGI+ PTARL+ WL Sbjct: 121 LGVLTVHLDDPTGYGRIVRDATGRITRIVEQKDANETQLAIHEVNTGILVCPTARLKTWL 180 Query: 180 AALSNDNAQGEYYLTDVIAAAVADGVEVVSANPVDITETLGVNSKVQLAELERAYQRRVA 239 A L NDNAQGEYYLTDVI A ++G+ + SA+P+ ETLGVNSKVQLAELER +QR +A Sbjct: 181 ATLRNDNAQGEYYLTDVIERAASEGLPITSAHPLAEWETLGVNSKVQLAELERIHQRNLA 240 Query: 240 NTLLEQGVTLLDPARLDVRGTLSCGRDVSIDVNCIFEGKVEIEDGASIGANCVVKDARIG 299 LLE GVTL+DPAR+D+RG L+CGRDV ID++CIFEG V + DG IGA+ V++DA I Sbjct: 241 QQLLEDGVTLIDPARIDIRGRLTCGRDVVIDIDCIFEGNVTLGDGVRIGAHAVIRDAAIQ 300 Query: 300 KGAQIKPFSHIDGAVVGAAAQVGPYARLRPGAELGEEVHIGNFVEVKKSRIAARSKANHL 359 GA+I PF HI+ A VGA +++GPYARLRPG EL E+VHIGNFVEVK S+IAA SKANHL Sbjct: 301 AGAEILPFCHIEQATVGAQSRIGPYARLRPGTELAEDVHIGNFVEVKNSQIAAHSKANHL 360 Query: 360 AYIGDAVIGSGVNVGAGVITCNYDGVNKFETVIEDDAFIGSDSQLVAPVRVGKGATIGAG 419 AY+GDA +GS VN+GAG ITCNYDG NKF T+IEDDAFIGSD+QLVAPVRVG+GAT+GAG Sbjct: 361 AYVGDATVGSRVNIGAGTITCNYDGANKFRTIIEDDAFIGSDTQLVAPVRVGRGATLGAG 420 Query: 420 TTLTKDAPAGQLTLSRAKQLSLPGWTRPVKVKK 452 TTLTKDAP GQLT+SRA+Q ++ GW RPVK KK Sbjct: 421 TTLTKDAPEGQLTVSRARQTTVNGWQRPVKQKK 453 >PA5552 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Pae Pseudomonas aeruginosa Length = 454 Score = 539 bits (1388), Expect = e-153, Method: Compositional matrix adjust. Identities = 267/453 (58%), Positives = 330/453 (72%), Gaps = 2/453 (0%) Query: 1 MNIVILAAGMGKRMQSALPKVLHPIAGKPLLRHVVDTAKVLAPTKLCVVYGHGGDAVPSS 60 + IVILAAG G RM+SALPKVLHPIAGKP+L HV+D A+ L P ++ VV GHG D V Sbjct: 3 LEIVILAAGQGTRMRSALPKVLHPIAGKPMLGHVIDCARQLQPERIHVVIGHGADLVRER 62 Query: 61 FADNTLSFALQEPQLGTGHAVAQALPFIDDNAPTLVLYGDVPLTTPATLQRLLAAAGEDK 120 A + L+F LQ QLGTGHAVAQALPF+ + L+LYGDVPL TLQRLLA D+ Sbjct: 63 MAADDLNFVLQAEQLGTGHAVAQALPFLSADQ-VLILYGDVPLIQLDTLQRLLAQVTPDQ 121 Query: 121 LAVLTITVADPTGYGRIVRED-GKITRIVEQKDASEAERAISEINTGIIAAPTARLRAWL 179 L++LT+ + DPTGYGRIVR+D G + IVE KDA+ A+R I EINTGI+A P RL WL Sbjct: 122 LSLLTVDMLDPTGYGRIVRDDQGAVQAIVEHKDATPAQRQIGEINTGILAVPGKRLADWL 181 Query: 180 AALSNDNAQGEYYLTDVIAAAVADGVEVVSANPVDITETLGVNSKVQLAELERAYQRRVA 239 LSNDNAQGEYYLTDVIA AV DG+ V SA P+D E GVN ++Q A+LER YQR A Sbjct: 182 GRLSNDNAQGEYYLTDVIAMAVGDGLVVASAQPLDAMEVQGVNDRMQQAQLERHYQRLRA 241 Query: 240 NTLLEQGVTLLDPARLDVRGTLSCGRDVSIDVNCIFEGKVEIEDGASIGANCVVKDARIG 299 L+ QGVTLLDP RLDVRG +S GRDV IDVN + EG+V IED IG NCV++D+ + Sbjct: 242 EELMRQGVTLLDPQRLDVRGEISVGRDVLIDVNVVLEGRVVIEDDVRIGPNCVIRDSVLR 301 Query: 300 KGAQIKPFSHIDGAVVGAAAQVGPYARLRPGAELGEEVHIGNFVEVKKSRIAARSKANHL 359 +GA IK SH++GA +G + GP+ARLRPG+ LG H+GNFVE+K +R+ SKA HL Sbjct: 302 RGAVIKANSHLEGAELGEGSDAGPFARLRPGSVLGARAHVGNFVELKNARLGEGSKAGHL 361 Query: 360 AYIGDAVIGSGVNVGAGVITCNYDGVNKFETVIEDDAFIGSDSQLVAPVRVGKGATIGAG 419 +Y+GDA +G+ N+GAG ITCNYDG NKF T + DD FIGS++ LVAP+++G GAT AG Sbjct: 362 SYLGDAELGANCNIGAGTITCNYDGANKFRTELGDDVFIGSNNSLVAPLKIGDGATTAAG 421 Query: 420 TTLTKDAPAGQLTLSRAKQLSLPGWTRPVKVKK 452 +T+T + PA L RA+Q +L W RP K+KK Sbjct: 422 STITHEVPAKNLAFGRARQKNLENWKRPEKIKK 454 >VC2762 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Vch Vibrio cholerae Length = 453 Score = 521 bits (1343), Expect = e-148, Method: Compositional matrix adjust. Identities = 256/451 (56%), Positives = 319/451 (70%) Query: 1 MNIVILAAGMGKRMQSALPKVLHPIAGKPLLRHVVDTAKVLAPTKLCVVYGHGGDAVPSS 60 + VILAAG G RM S +PKVLH +AGKP+++HV+DT L + +VYGHGGD + + Sbjct: 3 FSTVILAAGKGTRMHSNMPKVLHTLAGKPMVKHVIDTCNNLGAQNIHLVYGHGGDQMQQA 62 Query: 61 FADNTLSFALQEPQLGTGHAVAQALPFIDDNAPTLVLYGDVPLTTPATLQRLLAAAGEDK 120 A+ +++ LQ QLGTGHAV QA P D+ LVLYGDVPL + T++ LL A D Sbjct: 63 LANENVNWVLQAQQLGTGHAVDQASPHFQDDEKILVLYGDVPLISEDTIESLLEAQPTDG 122 Query: 121 LAVLTITVADPTGYGRIVREDGKITRIVEQKDASEAERAISEINTGIIAAPTARLRAWLA 180 +A+LT+ + DPTGYGRIVR+ G + IVEQKDASE ++ I E+NTG++ A L+ WLA Sbjct: 123 IALLTVVLEDPTGYGRIVRKRGPVVAIVEQKDASEEQKLIKEVNTGVLVATGRDLKRWLA 182 Query: 181 ALSNDNAQGEYYLTDVIAAAVADGVEVVSANPVDITETLGVNSKVQLAELERAYQRRVAN 240 L+N+NAQGEYYLTDVIAAA +G V + +P E GVN ++QLA LERA+Q R A Sbjct: 183 GLNNNNAQGEYYLTDVIAAAHDEGRAVEAVHPSHSIEVEGVNDRIQLARLERAFQARQAK 242 Query: 241 TLLEQGVTLLDPARLDVRGTLSCGRDVSIDVNCIFEGKVEIEDGASIGANCVVKDARIGK 300 LLEQGV L DPAR D+RGTL CG DV IDVN I EG V I + IGA ++KD I Sbjct: 243 KLLEQGVMLRDPARFDLRGTLQCGSDVEIDVNVIIEGNVSIGNNVVIGAGSILKDCEIDD 302 Query: 301 GAQIKPFSHIDGAVVGAAAQVGPYARLRPGAELGEEVHIGNFVEVKKSRIAARSKANHLA 360 I+P+S I+GA VG VGP+ RLRPGAEL ++ H+GNFVE+K +R+ SKANHL Sbjct: 303 NTVIRPYSVIEGATVGENCTVGPFTRLRPGAELRDDAHVGNFVEMKNARLGEGSKANHLT 362 Query: 361 YIGDAVIGSGVNVGAGVITCNYDGVNKFETVIEDDAFIGSDSQLVAPVRVGKGATIGAGT 420 Y+GDA IG GVNVGAGVITCNYDG NK +TVI DD F+GSD QLVAPV +G GATIGAGT Sbjct: 363 YLGDAEIGKGVNVGAGVITCNYDGANKHKTVIGDDVFVGSDCQLVAPVTIGNGATIGAGT 422 Query: 421 TLTKDAPAGQLTLSRAKQLSLPGWTRPVKVK 451 TLTK+ G+L ++RA + + GW RP K K Sbjct: 423 TLTKNVAEGELVITRAPERKIAGWQRPAKKK 453 >YPO4119 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Ype Yersinia pestis Length = 456 Score = 516 bits (1330), Expect = e-146, Method: Compositional matrix adjust. Identities = 248/451 (54%), Positives = 330/451 (73%) Query: 1 MNIVILAAGMGKRMQSALPKVLHPIAGKPLLRHVVDTAKVLAPTKLCVVYGHGGDAVPSS 60 M++VILAAG G RM S LPKVLHP+AGKP+++HV+D A L + +VYGHGG+ + + Sbjct: 6 MSVVILAAGKGTRMYSDLPKVLHPLAGKPMVQHVIDAAMKLGAQHVHLVYGHGGELLKKT 65 Query: 61 FADNTLSFALQEPQLGTGHAVAQALPFIDDNAPTLVLYGDVPLTTPATLQRLLAAAGEDK 120 AD +L++ LQ QLGTGHA+ QA P D+ L+LYGDVPL + TLQRLLAA E Sbjct: 66 LADPSLNWVLQAEQLGTGHAMQQAAPHFADDEDILMLYGDVPLISVDTLQRLLAAKPEGG 125 Query: 121 LAVLTITVADPTGYGRIVREDGKITRIVEQKDASEAERAISEINTGIIAAPTARLRAWLA 180 + +LT+ + +P+GYGRIVRE+G + IVE KDAS+A+R I+EINTGI+ A L+ WL+ Sbjct: 126 IGLLTVKLDNPSGYGRIVRENGDVVGIVEHKDASDAQREINEINTGILVANGRDLKRWLS 185 Query: 181 ALSNDNAQGEYYLTDVIAAAVADGVEVVSANPVDITETLGVNSKVQLAELERAYQRRVAN 240 L N+NAQGE+Y+TD+IA A ADG ++ + +P ++E GVN+++QL+ LER +Q A Sbjct: 186 LLDNNNAQGEFYITDIIALAHADGKKIATVHPTRLSEVEGVNNRLQLSALERVFQTEQAE 245 Query: 241 TLLEQGVTLLDPARLDVRGTLSCGRDVSIDVNCIFEGKVEIEDGASIGANCVVKDARIGK 300 LL GV LLDP+R D+RG L+ GRD++ID N I EG V + D IG CV+K+ IG Sbjct: 246 KLLLAGVMLLDPSRFDLRGELTHGRDITIDTNVIIEGHVILGDRVRIGTGCVLKNCVIGD 305 Query: 301 GAQIKPFSHIDGAVVGAAAQVGPYARLRPGAELGEEVHIGNFVEVKKSRIAARSKANHLA 360 ++I P++ ++ A + A VGP+ARLRPGAEL E H+GNFVE+KK+R+ SKA HL+ Sbjct: 306 DSEISPYTVLEDARLDANCTVGPFARLRPGAELAEGAHVGNFVEIKKARLGKGSKAGHLS 365 Query: 361 YIGDAVIGSGVNVGAGVITCNYDGVNKFETVIEDDAFIGSDSQLVAPVRVGKGATIGAGT 420 Y+GDA IG+GVN+GAG ITCNYDG NKF+T+I DD F+GSD+QLVAPV V GATIGAGT Sbjct: 366 YLGDAEIGAGVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVANGATIGAGT 425 Query: 421 TLTKDAPAGQLTLSRAKQLSLPGWTRPVKVK 451 T+T+D +L +SR KQ+ + GW RPVK K Sbjct: 426 TVTRDVAENELVISRVKQVHIQGWKRPVKKK 456 >HI0642 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Hin Haemophilus influenzae Length = 456 Score = 516 bits (1330), Expect = e-146, Method: Compositional matrix adjust. Identities = 240/451 (53%), Positives = 322/451 (71%) Query: 1 MNIVILAAGMGKRMQSALPKVLHPIAGKPLLRHVVDTAKVLAPTKLCVVYGHGGDAVPSS 60 ++ VILAAG G RM S LPKVLH IAGKP+++HV+DTA L + ++YGHGGD + + Sbjct: 6 LSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGSENIHLIYGHGGDLMRTH 65 Query: 61 FADNTLSFALQEPQLGTGHAVAQALPFIDDNAPTLVLYGDVPLTTPATLQRLLAAAGEDK 120 A+ +++ LQ QLGT HAV QA PF DN +VLYGD PL T TL++L+ A E+ Sbjct: 66 LANEQVNWVLQTEQLGTAHAVQQAAPFFKDNENIVVLYGDAPLITKETLEKLIEAKPENG 125 Query: 121 LAVLTITVADPTGYGRIVREDGKITRIVEQKDASEAERAISEINTGIIAAPTARLRAWLA 180 +A+LT+ + +PTGYGRI+RE+G + IVEQKDA+ + I E+NTG++ + A + WLA Sbjct: 126 IALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANAEQLNIKEVNTGVMVSDGASFKKWLA 185 Query: 181 ALSNDNAQGEYYLTDVIAAAVADGVEVVSANPVDITETLGVNSKVQLAELERAYQRRVAN 240 + N+NAQGEYYLTD+IA A D +VV+ D+ E G N+++QLA LER +Q + A+ Sbjct: 186 RVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYFQNKQAS 245 Query: 241 TLLEQGVTLLDPARLDVRGTLSCGRDVSIDVNCIFEGKVEIEDGASIGANCVVKDARIGK 300 LL +GV + DPAR D+RGTL G+DV IDVN I EG V++ D IG CV+K+ IG Sbjct: 246 KLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGTGCVLKNVVIGN 305 Query: 301 GAQIKPFSHIDGAVVGAAAQVGPYARLRPGAELGEEVHIGNFVEVKKSRIAARSKANHLA 360 +IKP+S ++ ++VG A +GP++RLRPGAEL E H+GNFVE+KKS + SK NHL Sbjct: 306 DVEIKPYSVLEDSIVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSKVNHLT 365 Query: 361 YIGDAVIGSGVNVGAGVITCNYDGVNKFETVIEDDAFIGSDSQLVAPVRVGKGATIGAGT 420 Y+GD+ IGS N+GAGVITCNYDG NKF+T+I DD F+GSD+QLVAPV+V GATIGAGT Sbjct: 366 YVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDDVFVGSDTQLVAPVKVANGATIGAGT 425 Query: 421 TLTKDAPAGQLTLSRAKQLSLPGWTRPVKVK 451 T+T+D +L ++R Q + GW RP+K K Sbjct: 426 TITRDVGENELVITRVAQRHIQGWQRPIKKK 456